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Molecular Cancer Therapeutics

1535-7163 · American Association for Cancer Research (AACR)

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Systematic Evaluation of Combination Strategies with Rezatapopt in p53 Y220C–Mutant Cancer Models

2026 · 0 citations

ABL209 (NEOK002): Designing an EGFR × MUC1 Bispecific TOP1i ADC with Promising Antitumor Activity and Enhanced Therapeutic Window

2026 · 0 citations

Mutant-Selective T-cell Receptor Therapy for Solid Tumors

2026 · 0 citations

Oncolytic Herpes Virus G47Δ Potentiates ADCC-Inducing Molecular Targeted Therapy via Coordinated Activation of Innate and Adaptive Immune Responses

2026 · 0 citations

HDAC Inhibition Unlocks Tumor Plasticity and Enhances Immunotherapy Response in Myc-Driven Small Cell Lung Cancer

2026 · 0 citations

YB-1 Inhibition Suppresses Osteosarcoma Growth and Reverses Tumor Immunosuppression

2026 · 0 citations

TRPM4 Expression as a Predictive Biomarker and a Mechanistic Driver of Acetalax Activity in Prostate Cancer: Preclinical Efficacy Studies

2026 · 0 citations

NAPRT Expression and Epigenetic Regulation in Pediatric Rhabdomyosarcoma as a Potential Biomarker for NAMPT Inhibition

2026 · 0 citations

An Integrin β6–Targeted Antibody–Drug Conjugate Optimized for Intravesical Delivery to Treat Non–Muscle-Invasive Bladder Cancer

2026 · 0 citations

Targeting the Chromatin-Modifying Enzyme, KDM5C, Enhances AKT Inhibition Response in ER+ Breast Cancer

2026 · 0 citations

Targeting NDUFS4 Disrupts Oxidative Phosphorylation and Induces Ferroptosis in Olaparib-Resistant Prostate Cancer

2026 · 0 citations

Identification of CD74-Positive Antigen-Presenting Glioma Cells in Primary Human Tumors and Murine Models of NF1 High-Grade Glioma

2026 · 0 citations

Bortezomib Restores Venetoclax Sensitivity in Acute Myeloid Leukemia Cell Lines with Intrinsic and Acquired Resistance

2026 · 0 citations

Balancing the Dual Mechanisms of Anti-VISTA mAbs for Antitumor Activity: CD8+ T-cell Responses and Fc-Dependent Depletion of VISTA-Expressing Immune Cells

2026 · 0 citations

JNJ-79032421, a Novel Membrane-Restricted Mesothelin-Targeting T Cell–Engaging Bispecific Antibody for the Treatment of Mesothelin-Positive Cancers

2026 · 0 citations

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