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References from The Pragmatic Clinical Trial—Reconciling Intention, Design, and State of Mind. Local targets link to admitted publications; unresolved targets remain external evidence.
Explanatory and pragmatic attitudes in therapeutical trials.
10.1016/0021-9681(67)90041-0 · 1967 · External reference
Making pragmatic clinical trials more pragmatic.
10.1001/jama.2024.19528 · 2024 · External reference
The PRECIS-2 tool: designing trials that are fit for purpose.
10.1136/bmj.h2147 · 2015 · External reference
A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers.
10.1016/j.jclinepi.2008.12.011 · 2009 · External reference
Improving the reporting of pragmatic trials: an extension of the CONSORT statement.
10.1136/bmj.a2390 · 2008 · External reference
Protocol for a SPIRIT extension for reporting pragmatic and explanatory trial protocols designed using the PRECIS tool (SPIRIT-PRECIS).
10.1016/j.jclinepi.2026.112380 · 2026 · External reference
Pragmatic evidence and the nature of randomized trials.
10.1016/j.jclinepi.2025.111961 · 2025 · External reference
Real-world evidence: How pragmatic are randomized controlled trials labeled as pragmatic?
10.1186/s12916-018-1038-2 · 2018 · External reference
An analysis of published trials found that current use of pragmatic trial labels is uninformative.
10.1016/j.jclinepi.2022.08.007 · 2022 · External reference
Thoughtful selection and use of scientific terms in clinical research: the case of ‘pragmatic’ trials.
10.1136/jim-2021-001789 · 2021 · External reference
Opportunities for pragmatic design elements in surgical trials.
10.1001/jamasurg.2025.3041 · 2025 · External reference
Symptom-based dosing for neonatal opioid withdrawal: the OPTimize NOW randomized clinical trial.
10.1001/jama.2026.5782 · 2026 · External reference
Sequenced care pathway vs pain navigator pathway for veterans with low back pain: the AIM-Back cluster randomized clinical trial.
10.1001/jamanetworkopen.2026.4421 · 2026 · External reference
Risk-based vs annual breast cancer screening: the WISDOM randomized clinical trial.
10.1001/jama.2025.24784 · 2026 · External reference
Home-based prehabilitation for older surgical patients with frailty: a randomized clinical trial.
10.1001/jamasurg.2025.5288 · 2026 · External reference
Per-protocol analyses of pragmatic trials.
10.1056/nejmsm1605385 · 2017 · External reference
