Research graph
References from Postural Orthostatic Tachycardia Syndrome (POTS). Local targets link to admitted publications; unresolved targets remain external evidence.
Postural tachycardia syndrome: reversal of sympathetic hyperresponsiveness and clinical improvement during sodium loading.
10.1016/0002-9343(82)90559-9 · 1982 · External reference
Idiopathic postural orthostatic tachycardia syndrome: an attenuated form of acute pandysautonomia?
10.1212/wnl.43.1_part_1.132 · 1993 · External reference
The face of postural tachycardia syndrome—insights from a large cross-sectional online community-based survey.
10.1111/joim.12895 · 2019 · External reference
Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss.
10.1111/joim.13245 · 2021 · External reference
Chronic autonomic symptom burden in long-COVID: a follow-up cohort study.
10.1007/s10286-025-01111-1 · 2025 · External reference
Epidemiology of postural orthostatic tachycardia syndrome.
10.1016/j.mayocp.2025.04.027 · 2025 · External reference
Cardiac origins of the postural orthostatic tachycardia syndrome.
10.1016/j.jacc.2010.02.043 · 2010 · External reference
Insights from invasive cardiopulmonary exercise testing of patients with myalgic encephalomyelitis/chronic fatigue syndrome.
10.1016/j.chest.2021.01.082 · 2021 · External reference
Regional blood volume and peripheral blood flow in postural tachycardia syndrome.
10.1152/ajpheart.00086.2004 · 2004 · External reference
Oscillatory cerebral blood flow is associated with impaired neurocognition and functional hyperemia in postural tachycardia syndrome during graded tilt.
10.1161/hypertensionaha.114.04576 · 2015 · External reference
Reduced stroke volume and brain perfusion drive postural hyperventilation in postural orthostatic tachycardia syndrome.
10.1016/j.jacbts.2024.04.011 · 2024 · External reference
Cognitive dysfunction in postural tachycardia syndrome.
10.1042/cs20140251 · 2015 · External reference
Mechanisms of tilt-induced vasovagal syncope in healthy volunteers and postural tachycardia syndrome patients without past history of syncope.
10.14814/phy2.14148 · 2019 · External reference
Comparison of the postural tachycardia syndrome (POTS) with orthostatic hypotension due to autonomic failure.
10.1016/0165-1838(94)90008-6 · 1994 · External reference
Mechanisms of blood pressure alterations in response to the Valsalva maneuver in postural tachycardia syndrome.
10.1007/bf02291382 · 2000 · External reference
The neuropathic postural tachycardia syndrome.
10.1056/nejm200010053431404 · 2000 · External reference
Vagal and sympathetic function in neuropathic postural tachycardia syndrome.
10.1161/hypertensionaha.118.11803 · 2019 · External reference
Small fiber neuropathy in children, adolescents, and young adults with chronic orthostatic intolerance and postural orthostatic tachycardia syndrome: a retrospective study.
10.1016/j.autneu.2024.103163 · 2024 · External reference
Small-fiber neuropathy with cardiac denervation in postural tachycardia syndrome.
10.1002/mus.24245 · 2014 · External reference
A prospective, 1-year follow-up study of postural tachycardia syndrome.
10.1016/j.mayocp.2012.02.020 · 2012 · External reference
Postural orthostatic tachycardia syndrome: the Mayo clinic experience.
10.1016/s0025-6196(11)61027-6 · 2007 · External reference
Autoimmune basis for postural tachycardia syndrome.
10.1161/jaha.113.000755 · 2014 · External reference
Postural orthostatic tachycardia syndrome is associated with elevated G-protein coupled receptor autoantibodies.
10.1161/jaha.119.013602 · 2019 · External reference
A functional cell-based bioassay for assessing adrenergic autoantibody activity in postural tachycardia syndrome.
10.1016/j.jtauto.2019.100006 · 2019 · External reference
Short-term exercise training improves the cardiovascular response to exercise in the postural orthostatic tachycardia syndrome.
10.1113/jphysiol.2012.233858 · 2012 · External reference
Cardiac atrophy after bed-rest deconditioning: a nonneural mechanism for orthostatic intolerance.
10.1161/01.cir.96.2.517 · 1997 · External reference
Cardiac atrophy after bed rest and spaceflight.
10.1152/jappl.2001.91.2.645 · 2001 · External reference
Cardiac atrophy in women following bed rest.
10.1152/japplphysiol.01162.2006 · 2007 · External reference
Renin-aldosterone paradox and perturbed blood volume regulation underlying postural tachycardia syndrome.
10.1161/01.cir.0000160356.97313.5d · 2005 · External reference
Increased plasma angiotensin II in postural tachycardia syndrome (POTS) is related to reduced blood flow and blood volume.
10.1042/cs20050254 · 2006 · External reference
Abnormalities of angiotensin regulation in postural tachycardia syndrome.
10.1016/j.hrthm.2010.11.009 · 2011 · External reference
Evidence for impaired renin activity in postural orthostatic tachycardia syndrome.
10.3390/jcm12144660 · 2023 · External reference
Decreased upright cerebral blood flow and cerebral autoregulation in normocapnic postural tachycardia syndrome.
10.1152/ajpheart.00138.2009 · 2009 · External reference
Stroke volume reduction impairs cerebrovascular regulation through ETCO2 in postural orthostatic tachycardia syndrome.
10.1007/s10286-025-01181-1 · 2026 · External reference
Direct vasodilator effect of hyperventilation-induced hypocarbia in autonomic failure patients.
10.1097/00000441-199105000-00002 · 1991 · External reference
Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019 National Institutes of Health expert consensus meeting—part 1.
10.1016/j.autneu.2021.102828 · 2021 · External reference
Long-term POTS outcomes survey: diagnosis, therapy, and clinical outcomes.
10.1161/jaha.123.033485 · 2024 · External reference
Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome.
10.1016/j.autneu.2011.02.004 · 2011 · External reference
Pooled rates and demographics of POTS following SARS-CoV-2 infection versus COVID-19 vaccination: systematic review and meta-analysis.
10.1016/j.autneu.2023.103132 · 2023 · External reference
Apparent risks of postural orthostatic tachycardia syndrome diagnoses after COVID-19 vaccination and SARS-Cov-2 Infection.
10.1038/s44161-022-00177-8 · 2022 · External reference
Canadian Cardiovascular Society position statement on postural orthostatic tachycardia syndrome (POTS) and related disorders of chronic orthostatic intolerance.
10.1016/j.cjca.2019.12.024 · 2020 · External reference
Cognitive function, health-related quality of life, and symptoms of depression and anxiety sensitivity are impaired in patients with the postural orthostatic tachycardia syndrome (POTS).
10.3389/fphys.2014.00230 · 2014 · External reference
Increasing orthostatic stress impairs neurocognitive functioning in chronic fatigue syndrome with postural tachycardia syndrome.
10.1042/cs20110241 · 2012 · External reference
Exercise and heart failure: a statement from the American Heart Association committee on exercise, rehabilitation, and prevention.
10.1161/01.cir.0000055013.92097.40 · 2003 · External reference
2015 Heart Rhythm Society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.
10.1016/j.hrthm.2015.03.029 · 2015 · External reference
Tilt table testing.
10.1001/jama.2024.0004 · 2024 · External reference
Diagnosis and management of postural orthostatic tachycardia syndrome.
10.1503/cmaj.211373 · 2022 · External reference
Effects of norepinephrine reuptake inhibition on postural tachycardia syndrome.
10.1161/jaha.113.000395 · 2013 · External reference
The prevalence of headache disorders in postural tachycardia syndrome: a systematic review and meta-analysis of the literature.
10.1177/03331024221095153 · 2022 · External reference
Orthostatic and non-orthostatic headache in postural tachycardia syndrome.
10.1177/0333102410382792 · 2011 · External reference
Gastrointestinal symptoms in patients with postural orthostatic tachycardia syndrome in relation to hemodynamic findings and immunological factors.
10.3389/fphys.2024.1342351 · 2024 · External reference
Prevalence of hypermobile Ehlers-Danlos syndrome in postural orthostatic tachycardia syndrome.
10.1016/j.autneu.2020.102637 · 2020 · External reference
Postural tachycardia in hypermobile Ehlers-Danlos syndrome: a distinct subtype?
10.1016/j.autneu.2017.10.001 · 2017 · External reference
Ehlers-Danlos syndrome and postural tachycardia syndrome: a relationship study.
10.1016/j.jns.2014.03.002 · 2014 · External reference
Patient characteristics of a telemedicine clinic for pediatric and young adult postural orthostatic tachycardia syndrome.
10.3390/jcm15041626 · 2026 · External reference
Association of postural orthostatic tachycardia syndrome, hypermobility spectrum disorders, and mast cell activation syndrome in young patients; prevalence, overlap and response to therapy depends on the definition.
10.3389/fneur.2025.1513199 · 2025 · External reference
Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort.
10.1111/joim.12161 · 2014 · External reference
Clinical characteristics of a novel subgroup of chronic fatigue syndrome patients with postural orthostatic tachycardia syndrome.
10.1111/joim.12022 · 2013 · External reference
Use of time-frequency analysis to investigate temporal patterns of cardiac autonomic response during head-up tilt in chronic fatigue syndrome.
10.1016/j.autneu.2004.05.001 · 2004 · External reference
Evaluation of the relationship between mast cell activation and postural orthostatic tachycardia syndrome in children and adolescents.
10.14744/nci.2023.64920 · 2024 · External reference
mast cell activation disorder and postural orthostatic tachycardia syndrome: a clinical association.
10.1161/jaha.121.021002 · 2021 · External reference
Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS).
10.1177/0961203315587566 · 2015 · External reference
Utility of salivary gland biopsy in diagnosing Sjogren’s syndrome in a POTS patient population.
10.1016/j.autneu.2020.102694 · 2020 · External reference
Dry eye syndrome and sicca complex are commonly found in patients with postural orthostatic tachycardia syndrome.
10.2147/opth.s279520 · 2020 · External reference
Prevalence of orthostatic intolerance in long COVID clinic patients and healthy volunteers: a multicenter study.
10.1002/jmv.29486 · 2024 · External reference
Prospective evaluation of autonomic dysfunction in post-acute sequela of COVID-19.
10.1016/j.jacc.2022.03.357 · 2022 · External reference
Autonomic dysfunction in post-COVID patients with and without neurological symptoms: a prospective multidomain observational study.
10.1007/s00415-021-10735-y · 2022 · External reference
Objective hemodynamic cardiovascular autonomic abnormalities in post-acute sequelae of COVID-19.
10.1016/j.cjca.2022.12.002 · 2023 · External reference
Autonomic nerve involvement in post-acute sequelae of SARS-CoV-2 syndrome (PASC).
10.3390/jcm12010073 · 2022 · External reference
High incidence of autonomic dysfunction and postural orthostatic tachycardia syndrome in patients with long COVID: implications for management and health care planning.
10.1016/j.amjmed.2023.06.010 · 2025 · External reference
Screening for postural orthostatic tachycardia syndrome using 24-hour electrocardiogram recording in patients with long coronavirus disease.
10.1016/j.hroo.2025.04.011 · 2025 · External reference
Characterization of postural orthostatic tachycardia syndrome in long COVID: self-reported data from the LISTEN study.
10.1016/j.jacadv.2025.101873 · 2025 · External reference
Prevalence and clinical impact of postural orthostatic tachycardia syndrome in highly symptomatic long COVID.
10.1161/circep.124.013629 · 2025 · External reference
Postural orthostatic tachycardia syndrome and orthostatic hypotension post COVID-19.
10.2174/1871526522666220610143504 · 2023 · External reference
Exercise training versus propranolol in the treatment of the postural orthostatic tachycardia syndrome.
10.1161/hypertensionaha.111.172262 · 2011 · External reference
Semi-supervised exercise training program more effective for individuals with postural orthostatic tachycardia syndrome in randomized controlled trial.
10.1007/s10286-023-00970-w · 2023 · External reference
Effect of high dietary sodium intake in patients with postural tachycardia syndrome.
10.1016/j.jacc.2021.03.005 · 2021 · External reference
Compression garment reduces orthostatic tachycardia and symptoms in patients with postural orthostatic tachycardia syndrome.
10.1016/j.jacc.2020.11.040 · 2021 · External reference
A community-based trial of commercially available compression tights in patients with postural orthostatic tachycardia syndrome.
10.1016/j.jacep.2024.09.033 · 2025 · External reference
Abdominal-only compression garments reduce orthostatic tachycardia and improve symptoms in patients with postural orthostatic tachycardia syndrome.
10.1016/j.cjca.2025.11.038 · 2026 · External reference
Acetylcholinesterase inhibition improves tachycardia in postural tachycardia syndrome.
10.1161/circulationaha.104.497594 · 2005 · External reference
Body mass index (BMI) is associated with the therapeutic response to oral rehydration solution in children with postural tachycardia syndrome.
10.1007/s00246-016-1436-1 · 2016 · External reference
Hemocytometric measures predict the efficacy of oral rehydration for children with postural tachycardia syndrome.
10.1016/j.jpeds.2017.04.034 · 2017 · External reference
The benefits of oral rehydration on orthostatic intolerance in children with postural tachycardia syndrome.
10.1016/j.jpeds.2019.07.041 · 2019 · External reference
Postural orthostatic tachycardia syndrome: JACC focus seminar.
10.1016/j.jacc.2018.11.059 · 2019 · External reference
Acute volume loading and exercise capacity in postural tachycardia syndrome.
10.1152/japplphysiol.00367.2014 · 2014 · External reference
Hemodynamic and symptomatic effects of acute interventions on tilt in patients with postural tachycardia syndrome.
10.1007/bf02291387 · 2000 · External reference
Effects of intermittent intravenous saline infusions in patients with medication-refractory postural tachycardia syndrome.
10.1007/s10840-017-0225-y · 2017 · External reference
Evaluation of abdominal compression band for pediatric postural tachycardia syndrome: a crossover study.
10.3389/fped.2025.1573091 · 2025 · External reference
Effects of passive heating on central blood volume and ventricular dimensions in humans.
10.1113/jphysiol.2007.143057 · 2008 · External reference
Worsening postural tachycardia syndrome is associated with increased glucose-dependent insulinotropic polypeptide secretion.
10.1161/hypertensionaha.121.17852 · 2022 · External reference
A double-blind placebo-controlled cross-over study of the vascular effects of midodrine in neuropathic compared with hyperadrenergic postural tachycardia syndrome.
10.1042/cs20130222 · 2014 · External reference
Neurogenic orthostatic hypotension: a double-blind, placebo-controlled study with midodrine.
10.1016/0002-9343(93)90230-m · 1993 · External reference
Propranolol decreases tachycardia and improves symptoms in the postural tachycardia syndrome: less is more.
10.1161/circulationaha.108.846501 · 2009 · External reference
Low-dose propranolol and exercise capacity in postural tachycardia syndrome: a randomized study.
10.1212/wnl.0b013e318293e310 · 2013 · External reference
Randomized trial of ivabradine in patients with hyperadrenergic postural orthostatic tachycardia syndrome.
10.1016/j.jacc.2020.12.029 · 2021 · External reference
Ivabradine, propranolol, and placebo for postural orthostatic tachycardia syndrome (POTS): a randomized crossover trial.
10.1016/j.jacc.2026.03.167 · 2026 · External reference
Efficacy of propranolol, bisoprolol, and pyridostigmine for postural tachycardia syndrome: a randomized clinical trial.
10.1007/s13311-018-0612-9 · 2018 · External reference
Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome.
10.1016/j.hrthm.2012.05.002 · 2012 · External reference
Using clonidine for neuromodulation in patients with postural orthostatic tachycardia syndrome.
10.1016/j.hrthm.2025.05.003 · 2025 · External reference
Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.
10.1001/jama.2009.351 · 2009 · External reference
Hemodynamic profiles and tolerability of modafinil in the treatment of postural tachycardia syndrome: a randomized, placebo-controlled trial.
10.1097/jcp.0000000000000221 · 2014 · External reference
Long-term outcomes in patients with postural orthostatic tachycardia syndrome with an average follow-up of over 20 years.
10.1111/joim.70104 · 2026 · External reference
