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References from Depression and SSRI Treatment During Pregnancy—Prioritizing Maternal Mental Health. Local targets link to admitted publications; unresolved targets remain external evidence.
The international prevalence of antidepressant use before, during, and after pregnancy: a systematic review and meta-analysis of timing, type of prescriptions and geographical variability.
10.1016/j.jad.2019.12.014 · 2020 · External reference
Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United States.
10.1016/j.jad.2011.07.004 · 2011 · External reference
The genetics of major depressive disorder: current insights.
2024 · External reference
The neurobiology of major depressive disorder: updates and perspectives from proteomics.
10.1016/j.pneurobio.2025.102855 · 2025 · External reference
Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety.
10.1038/s41591-024-03057-9 · 2024 · External reference
Neurochemical and energetic alterations in depression: a narrative review of potential PET biomarkers.
10.3390/ijms27031267 · 2026 · External reference
Magnetic resonance imaging connectivity features associated with response to transcranial magnetic stimulation in major depressive disorder.
10.1016/j.pscychresns.2024.111846 · 2024 · External reference
Effect of depression and serotonin reuptake inhibitors antidepressant treatment during pregnancy on protein expression in the human placenta: a quantitative proteomics analysis.
10.1371/journal.pone.0322090 · 2025 · External reference
Pathophysiological mechanisms implicated in postpartum depression.
10.1016/j.yfrne.2018.12.001 · 2019 · External reference
Neural correlates of peripartum depression: a systematic review, meta-analysis and comparison to major depressive disorder.
10.1038/s41380-025-03227-2 · 2025 · External reference
Current pharmacotherapy approaches and novel GABAergic antidepressant development in postpartum depression.
10.1080/19585969.2023.2262464 · 2023 · External reference
The persisting effect of maternal mood in pregnancy on childhood psychopathology.
10.1017/s0954579414000029 · 2014 · External reference
Prioritizing maternal mental health in addressing morbidity and mortality.
10.1001/jamapsychiatry.2023.5648 · 2024 · External reference
Meta-analysis of antenatal depression and adverse birth outcomes in US populations, 2010-20.
10.1377/hlthaff.2021.00801 · 2021 · External reference
Association between hyperemesis gravidarum and depression: a national register-based controlled study in Finland.
10.1016/s2215-0366(25)00271-8 · 2025 · External reference
Depression and anxiety in early pregnancy and risk for preeclampsia.
10.1016/s0029-7844(99)00602-x · 2000 · External reference
Alterations in amygdala-prefrontal circuits in infants exposed to prenatal maternal depression.
10.1038/tp.2016.146 · 2016 · External reference
Maternal stress during pregnancy alters fetal cortico-cerebellar connectivity in utero and increases child sleep problems after birth.
10.1038/s41598-021-81681-y · 2021 · External reference
Associations of maternal prenatal stress and depressive symptoms with childhood neurobehavioral outcomes in the ECHO cohort of the NICHD fetal growth studies: fetal growth velocity as a potential mediator.
10.1016/j.jaac.2022.03.021 · 2022 · External reference
Independent prediction of child psychiatric symptoms by maternal mental health and child polygenic risk scores.
10.1016/j.jaac.2023.08.018 · 2024 · External reference
Association of prenatal maternal psychological distress with fetal brain growth, metabolism, and cortical maturation.
10.1001/jamanetworkopen.2019.19940 · 2020 · External reference
Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: implications for fetal programming.
10.1002/dev.20549 · 2011 · External reference
Could a phase model help to improve translational animal research?
10.1002/ame2.12284 · 2022 · External reference
Relevance of rodent models of depression in clinical practice: can we overcome the obstacles in translational neuropsychiatry?
10.1093/ijnp/pyy037 · 2018 · External reference
Tianeptine, but not fluoxetine, decreases avoidant behavior in a mouse model of early developmental exposure to fluoxetine.
10.1038/s41598-021-02074-9 · 2021 · External reference
In utero exposure to citalopram mitigates maternal stress effects on fetal brain development.
10.1021/acschemneuro.9b00180 · 2019 · External reference
Enabling pregnant women and their physicians to make informed medication decisions using artificial intelligence.
10.1007/s10928-020-09685-1 · 2020 · External reference
Trajectories of depressive and anxiety symptoms across pregnancy and postpartum in selective serotonin reuptake inhibitor-treated women.
10.1176/appi.prcp.20210034 · 2022 · External reference
Onset timing, thoughts of self-harm, and diagnoses in postpartum women with screen-positive depression findings.
10.1001/jamapsychiatry.2013.87 · 2013 · External reference
Social determinants of health associated with perinatal health outcomes in different racial/ethnic groups: a narrative review of reviews.
10.1177/15409996261418118 · 2026 · External reference
First-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects.
10.1056/nejmoa067407 · 2007 · External reference
Use of selective serotonin-reuptake inhibitors in pregnancy and the risk of birth defects.
10.1056/nejmoa066584 · 2007 · External reference
Antidepressant use in pregnancy and the risk of cardiac defects.
10.1056/nejmoa1312828 · 2014 · External reference
Association of antidepressant use during pregnancy with risk of neurodevelopmental disorders in children.
10.1001/jamainternmed.2022.4268 · 2022 · External reference
Maternal use of specific antidepressant medications during early pregnancy and the risk of selected birth defects.
10.1001/jamapsychiatry.2020.2453 · 2020 · External reference
Untangling the risks of antidepressants in pregnancy.
10.1056/nejmp2511434 · 2025 · External reference
Different psychological interventions for perinatal depression: a systematic review and meta-analysis of randomized controlled trials.
10.1186/s12888-025-07462-3 · 2025 · External reference
Perinatal psychiatry: balancing maternal-fetal exposures to mental disorders and drug treatments.
10.1016/j.semperi.2025.152076 · 2025 · External reference
Antidepressants for preventing postnatal depression.
10.1002/14651858.cd004363.pub3 · 2018 · External reference
Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment.
10.1001/jama.295.5.499 · 2006 · External reference
Antidepressant discontinuation before or during pregnancy and risk of psychiatric emergency in Denmark: a population-based propensity score-matched cohort study.
10.1371/journal.pmed.1003895 · 2022 · External reference
Does antidepressant use attenuate the risk of a major depressive episode in pregnancy?
10.1097/ede.0b013e3182306847 · 2011 · External reference
The risk of relapse of depression during pregnancy after discontinuation of antidepressants: a systematic review and meta-analysis.
10.4088/jcp.19r13134 · 2020 · External reference
Lasting income costs of mental and physical illness.
10.1001/jamahealthforum.2026.0196 · 2026 · External reference
Exposure to selective serotonin reuptake inhibitors in early pregnancy and the risk of miscarriage.
10.1097/aog.0000000000000447 · 2014 · External reference
SSRI use during pregnancy and risk of stillbirth and neonatal mortality.
10.1176/appi.ajp.2012.11081251 · 2013 · External reference
Impact of antidepressant treatment during pregnancy on obstetric outcomes among women previously treated for depression: an observational cohort study.
10.1038/jp.2017.92 · 2017 · External reference
Antidepressant use late in pregnancy and risk of persistent pulmonary hypertension of the newborn.
10.1001/jama.2015.5605 · 2015 · External reference
Re: SSRI use during pregnancy and risk for postpartum haemorrhage: a national register-based cohort study in Sweden: this registry-based large study of postpartum haemorrhage with SSRI usage, despite crucial limitations, shows any increased risk to be reassuringly low and clinically non-significant.
10.1111/1471-0528.16586 · 2021 · External reference
Preterm birth and antidepressant medication use during pregnancy: a systematic review and meta-analysis.
10.1371/journal.pone.0092778 · 2014 · External reference
Pregnancy complications following prenatal exposure to SSRIs or maternal psychiatric disorders: results from population-based national register data.
10.1176/appi.ajp.2015.14121575 · 2015 · External reference
Neonatal withdrawal syndrome following late in utero exposure to selective serotonin reuptake inhibitors: a systematic review and meta-analysis of observational studies.
10.1159/000516031 · 2021 · External reference
Neonatal morbidity after maternal use of antidepressant drugs during pregnancy.
10.1542/peds.2016-0181 · 2016 · External reference
Neonatal outcome and adaption after in utero exposure to antidepressants: a systematic review and meta-analysis.
10.1111/acps.13367 · 2022 · External reference
The roles of maternal depression, serotonin reuptake inhibitor treatment, and concomitant benzodiazepine use on infant neurobehavioral functioning over the first postnatal month.
10.1176/appi.ajp.2015.14080989 · 2016 · External reference
Consensus panel recommendations for the pharmacological management of pregnant women with depressive disorders.
10.3390/ijerph20166565 · 2023 · External reference
Depression and anxiety during pregnancy: a risk factor for obstetric, fetal and neonatal outcome? a critical review of the literature.
10.1080/14767050701209560 · 2007 · External reference
Untreated depression during pregnancy: short- and long-term effects in offspring. a systematic review.
10.1016/j.neuroscience.2015.09.001 · 2017 · External reference
Prenatal antidepressant exposure and offspring brain morphologic trajectory.
10.1001/jamapsychiatry.2023.3161 · 2023 · External reference
Prenatal selective serotonin reuptake inhibitor exposure, depression, and brain morphology in middle childhood: results from the ABCD study.
10.1016/j.bpsgos.2022.02.005 · 2022 · External reference
Maternal depression, prenatal SSRI exposure, and brain trajectories in childhood.
10.1001/jamapsychiatry.2023.2664 · 2023 · External reference
Antidepressant use during pregnancy and psychiatric disorders in offspring: Danish nationwide register based cohort study.
10.1136/bmj.j3668 · 2017 · External reference
Prenatal antidepressant exposure and risk of depression and anxiety disorders: an electronic health records-based cohort study.
10.1016/j.jaac.2025.03.026 · 2026 · External reference
Associations between maternal depressive symptoms and selective serotonin reuptake inhibitor antidepressant treatment on internalising and anxiety behaviours in children: 12-year longitudinal study.
10.1192/bjo.2022.623 · 2023 · External reference
Long-term prenatal effects of antidepressant use on the risk of affective disorders in the offspring: a register-based cohort study.
10.1038/s41386-021-01005-6 · 2021 · External reference
Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data.
10.1001/archpsyc.63.8.898 · 2006 · External reference
Risk-benefit decision making for treatment of depression during pregnancy.
10.1176/appi.ajp.157.12.1933 · 2000 · External reference
Canadian Network for Mood and Anxiety Treatments 2024 clinical practice guideline for the management of perinatal mood, anxiety, and related disorders: guide de pratique 2024 du Canadian Network for Mood and Anxiety Treatments pour le traitement des troubles de l’humeur, des troubles anxieux et des troubles connexes périnatals.
10.1177/07067437241303031 · 2025 · External reference
Synthesizing cohort study results to promote knowledge transfer of safety data regarding gestational antidepressant exposure and offspring congenital anomalies: a test of concept.
10.1002/bdr2.2496 · 2025 · External reference
Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment.
10.1001/jama.295.5.499 · 2006 · External reference
The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials.
10.1038/s41398-021-01638-7 · 2021 · External reference
Changes in sertraline plasma concentrations across pregnancy and postpartum.
10.1002/cpt.2746 · 2022 · External reference
Relevance of pharmacogenetic analyses and therapeutic drug monitoring of antidepressants for an individualized treatment of peripartum psychopathology.
10.1097/yic.0000000000000520 · 2024 · External reference
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