Research graph
References from Interventions for treatment of herpes labialis (cold sores on the lips). Local targets link to admitted publications; unresolved targets remain external evidence.
Recurrent herpes labialis in the pediatric population: prevalence, therapeutic studies, and associated complications
10.1111/pde.13978 · 2019 · External reference
Recurrent herpes labialis among health school students in Kahramanmaras, Turkey: a cross-sectional survey
10.1016/j.dsi.2012.10.004 · 2013 · External reference
Natural history, management and complications of herpes labialis
10.1002/jmv.1890410506 · 1993 · External reference
Immune, stress, and mood markers related to recurrent oral herpes outbreaks
10.1016/s1079-2104(98)90149-4 · 1998 · External reference
Penciclovir cream for the treatment of herpes simplex labialis. A randomized, multicenter, double-blind, placebo-controlled trial
1997 · External reference
Risk factors of herpes simplex type 1 (HSV-1) infection and lifestyle factors associated with HSV-1 manifestations
10.1023/a:1015652713971 · 2001 · External reference
Patients' profile, burden of disease and quality of life in recurrent herpes labialis: a survey conducted in USA and France
10.1111/j.1468-3083.2011.04348.x · 2012 · External reference
Erythema multiforme and latent herpes simplex infection
1992 · External reference
Erythema multiforme associated with herpes labialis
2013 · External reference
Prospects for control of herpes simplex virus disease through immunization
10.1086/313687 · 2000 · External reference
Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis
10.1002/14651858.cd002898.pub5 · 2015 · External reference
Oral and perioral herpes simplex virus type 1 (HSV-1) infection: review of its management
2006 · External reference
Interventions for prevention of herpes simplex labialis (cold sores on the lips)
10.1002/14651858.cd010095.pub2 · 2015 · External reference
Inhibition of herpes simplex virus-induced DNA polymerase activity and viral DNA replication by 9-(2-hydroxyethoxymethyl)guanine and its triphosphate
10.1128/jvi.32.1.72-77.1979 · 1979 · External reference
New strategies against drug resistance to herpes simplex virus
10.1038/ijos.2016.3 · 2016 · External reference
Penciclovir cream for the treatment of sunlight-induced herpes simplex labialis: a randomized, double-blind, placebo-controlled trial. Penciclovir Cream Herpes Labialis Study Group
10.1016/s0149-2918(00)87979-5 · 2000 · External reference
Efficacy and safety of nucleoside antiviral drugs for treatment of recurrent herpes labialis: a systematic review and meta-analysis
10.1111/jop.12534 · 2017 · External reference
Herpes simplex virus infection
10.1053/spid.2002.29752 · 2002 · External reference
Single-day treatment for orolabial and genital herpes: a brief review of pathogenesis and pharmacology
10.2147/tcrm.s1664 · 2008 · External reference
Tromantadine inhibits a late step in herpes simplex virus type 1 replication and syncytium formation
10.1016/0166-3542(90)90045-9 · 1990 · External reference
Efficacy of tromantadine and aciclovir in the topical treatment of recurrent herpes orofacialis. Comparison in a clinical trial
1993 · External reference
Profiles on new drugs
2001 · External reference
Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial
10.1136/bmjopen-2018-026201 · 2019 · External reference
Treatment of herpes simplex by zinc sulphate
2005 · External reference
Honey and its nutritional and anti-inflammatory value
10.1186/s12906-020-03170-5 · 2021 · External reference
The role of zinc in antiviral immunity
10.1093/advances/nmz013 · 2019 · External reference
Efficacy of photodynamic therapy on the treatment of herpes labialis: a systematic review
10.1016/j.pdpdt.2019.08.018 · 2020 · External reference
Mechanisms of photodynamic inactivation of herpes simplex viruses: comparison between methylene blue, light plus electricity, and hematoporhyrin plus light
10.1172/jci109686 · 1980 · External reference
Efficacy of low-level laser therapy in management of recurrent herpes labialis: a systematic review
10.1007/s10103-018-2542-5 · 2018 · External reference
Photobiomodulation in oral medicine: a review
10.1111/jicd.12148 · 2016 · External reference
Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis
10.4317/jced.53679 · 2017 · External reference
Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: a multicenter, randomized, placebo-controlled trial
10.1067/mjd.2001.116215 · 2001 · External reference
Interventions for treatment of herpes simplex labialis (cold sores on the lips)
10.1002/14651858.cd009375 · 2011 · External reference
Interventions for treatment of herpes labialis (cold sores on the lips)
10.1002/14651858.cd015216 · 2022 · External reference
Measurement of health status. Ascertaining the minimal clinically important difference
10.1016/0197-2456(89)90005-6 · 1989 · External reference
Interventions for bacterial folliculitis and boils (furuncles and carbuncles)
10.1002/14651858.cd013099 · 2018 · External reference
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Practical methods for incorporating summary time-to-event data into meta-analysis
10.1186/1745-6215-8-16 · 2007 · External reference
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A simple method for the analysis of clustered binary data
10.2307/2532311 · 1992 · External reference
Multiarm studies and how to handle them in a meta-analysis: A tutorial
10.1002/cesm.12033 · 2023 · External reference
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Synthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline
10.1136/bmj.l6890 · 2020 · External reference
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2008 · External reference
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Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials
10.1128/aac.46.7.2238–2243.2002 · 2002 · External reference
Acyclovir cream for treatment of herpes simplex labialis: results of two randomized, double-blind, vehicle-controlled, multicenter clinical trials
10.1128/aac.46.7.2238–2243.2002 · 2002 · External reference
High-dose, short-duration, early valacyclovir therapy for episodic treatment of cold sores: results of two randomized, placebo-controlled, multicenter studies
10.1128/aac.47.3.1072-1080.2003 · 2003 · External reference
High-dose, short-duration, early valacyclovir therapy for episodic treatment of cold sores: results of two randomized, placebo-controlled, multicenter studies
10.1128/aac.47.3.1072-1080.2003 · 2003 · External reference
N-docosanol 10% cream in the treatment of recurrent herpes labialis: a randomised, double-blind, placebo-controlled study
10.2340/0001555576479481 · 1996 · External reference
A clinical evaluation of a novel liposomal carrier for acyclovir in the topical treatment of recurrent herpes labialis
10.1016/s1079-2104(99)70164-2 · 1999 · External reference
Uncaria tomentosa in the treatment of the herpes labialis: randomized double-blind trial
2010 · External reference
Topical acyclovir in the management of recurrent herpes labialis
10.1111/j.1365-2133.1983.tb03548.x · 1983 · External reference
Randomised controlled trial of topical kanuka honey for the treatment of cold sores
10.1016/j.aimed.2014.09.001 · 2014 · External reference
Can clinical trials requiring frequent participant contact be conducted over the Internet? Results from an online randomized controlled trial evaluating a topical ointment for herpes labialis
2004 · External reference
Failure of acyclovir cream in treatment of recurrent herpes labialis
10.1136/bmj.291.6487.7 · 1985 · External reference
Effective treatment of herpes simplex labialis with penciclovir cream: combined results of two trials
10.14219/jada.archive.2002.0169 · 2002 · External reference
Melaleuca alternifolia (tea tree) oil gel (6%) for the treatment of recurrent herpes labialis
10.1093/jac/48.3.450 · 2001 · External reference
Iontophoresis of vidarabine monophosphate for herpes orolabialis
10.1093/infdis/154.6.930 · 1986 · External reference
Herpes simplex virus-1 and hand sanitizer: a pilot study
2024 · External reference
A randomised double-blind study comparing the effect of 1072-nm light against placebo for the treatment of herpes labialis
10.1111/j.1365-2230.2006.02191.x · 2006 · External reference
Determining therapeutic efficacy in recurrent herpes labialis by lesion size analysis
10.1016/0030-4220(91)90160-e · 1991 · External reference
Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores
10.1111/jop.13647 · 2012 · External reference
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Efficacy of adjuvant photobiomodulation therapy in recurrent herpes labialis, a randomized clinical trial study
10.1016/j.pdpdt.2024.104282 · 2024 · External reference
Combination treatment with famciclovir and a topical corticosteroid gel versus famciclovir alone for experimental ultraviolet radiation-induced herpes simplex labialis: a pilot study
10.1086/315528 · 2000 · External reference
Efficacy of a topical herbal and mineral formulation (Dynamiclear) for the treatment of herpes simplex labialis in the community setting: study protocol for a randomised, double-blind placebo-controlled trial
10.1136/bmjopen-2019-031876 · 2020 · External reference
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Comparative study with a lip balm containing 0.5% propolis special extract GH 2002 versus 5% aciclovir cream in patients with herpes labialis in the papular/erythematous stage: a single-blind, randomized, two-arm study
10.1016/j.curtheres.2017.10.004 · 2018 · External reference
Efficacy and safety of aciclovir mucoadhesive buccal tablet in immunocompetent patients with labial herpes (LIP Trial): a double-blind, placebo-controlled, self-initiated trial
2014 · External reference
Penciclovir cream for the treatment of sunlight-induced herpes simplex labialis: a randomized, double-blind, placebo-controlled trial. Penciclovir Cream Herpes Labialis Study Group
10.1016/s0149-2918(00)87979-5 · 2000 · External reference
Sage leaves and rhubarb roots versus aciclovir in treating Herpes labialis
10.1055/s-2005-925482 · 2005 · External reference
Valaciclovir as a single dose during prodrome of herpes facialis: a pilot randomized double-blind clinical trial
10.1046/j.1365-2133.2003.05062.x · 2003 · External reference
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution
10.1016/0166-3542(95)00010 · 1995 · External reference
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Early treatment of cold sores with topical ME-609 decreases the frequency of ulcerative lesions: a randomized, double-blind, placebo-controlled, patient-initiated clinical trial
10.1016/j.jaad.2010.08.012 · 2011 · External reference
Antiherpetic effects of Gynura procumbens
10.1155/2013/394865 · 2013 · External reference
Lip creams with propolis special extract GH 2002 0.5% versus aciclovir 5.0% for herpes labialis (vesicular stage): randomized, controlled double-blind study
10.1007/s10354-018-0667-6 · 2019 · External reference
A double-blind, placebo-controlled study of topical tetracaine in the treatment of herpes labialis
10.1016/s0190-9622(99)70260-4 · 1999 · External reference
Randomized clinical study comparing Compeed cold sore patch to acyclovir cream 5% in the treatment of herpes simplex labialis
10.1111/j.1468-3083.2008.02761.x · 2008 · External reference
Single-day, patient-initiated Famciclovir treatment for recurrent herpes simplex: A randomized, placebo-controlled, double-blind, parallel-group, multicenter phase 3 study
10.3812/jocd.35.488 · 2018 · External reference
A phase 3, randomized, double-blind, placebo-controlled study evaluating a single, patient-initiated dose of amenamevir for recurrent herpes labialis
10.1111/1346-8138.16608 · 2023 · External reference
Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores
2012 · External reference
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Efficacy and safety of foscarnet for recurrent orolabial herpes: a multicentre randomized double-blind study
1988 · External reference
Topical application of penciclovir cream for the treatment of herpes simplex facialis/labialis: A randomized, double-blind, multicentre, aciclovir-controlled trial
10.1080/095466302317584412 · 2002 · External reference
Topical iontophoretic administration of acyclovir for the episodic treatment of herpes labialis: a randomized, double-blind, placebo-controlled, clinic-initiated trial
10.1086/505872 · 2006 · External reference
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Clinical efficacy of topical docosanol 10% cream for herpes simplex labialis: a multicenter, randomized, placebo-controlled trial
10.1067/mjd.2001.116215 · 2001 · External reference
Combined herbal preparation for topical treatment of herpes labialis
10.1159/000057255 · 2001 · External reference
Kanuka honey versus aciclovir for the topical treatment of herpes simplex labialis: a randomised controlled trial
10.1136/bmjopen-2018-026201 · 2019 · External reference
Topical undecylenic acid for herpes simplex labialis: A multicenter, placebo-controlled trial
10.1086/514042 · 1997 · External reference
A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis
10.1111/j.1600-0714.2011.01037.x · 2012 · External reference
Topical 5 percent acyclovir in polyethylene glycol for herpes simplex labialis. Antiviral effect without clinical benefit
10.1016/0002-9343(82)90115-2 · 1982 · External reference
Early, patient-initiated treatment of herpes labialis with topical 10% acyclovir
10.1128/aac.25.5.553 · External reference
Early application of topical 15% idoxuridine in dimethyl sulfoxide shortens the course of herpes simplex labialis: a multicenter placebo-controlled trial
10.1093/infdis/161.2.191 · 1990 · External reference
Treatment of recurrent herpes simplex labialis with oral acyclovir
10.1093/infdis/161.2.185 · 1990 · External reference
Single-dose, patient-initiated famciclovir: a randomized, double-blind, placebo-controlled trial for episodic treatment of herpes labialis
10.1016/j.jaad.2006.02.031 · 2006 · External reference
Topical acyclovir therapy in patients with recurrent orofacial herpessimplex infections
10.1093/jac/12.suppl_b.89 · 1983 · External reference
Topical lipophilic epigallocatechin-3-gallate on herpes labialis: a phase II clinical trial of AverTeaX formula
10.1016/j.oooo.2015.08.018 · 2015 · External reference
Comparison of the effectiveness of mellisan gel and acyclovir 5% cream in the improvement of recurrent herpes labialis
10.22088/jbums.17.7.15 · 2015 · External reference
Efficacy of photobiomodulation therapy in recurrent herpes labialis management: a randomized controlled trial
10.1007/s00784-024-05541-5 · 2024 · External reference
Evaluating the effectiveness of topical olive leaf extract emulgel in managing recurrent herpes labialis: a randomized controlled clinical study
10.1038/s41598-024-81805-0 · 2024 · External reference
Effect of combined antimicrobial photodynamic therapy and photobiomodulation therapy in the management of recurrent herpes labialis: a randomized controlled trial
10.1038/s41598-025-01331-5 · 2025 · External reference
Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis
10.1186/s12903-024-04948-6 · 2024 · External reference
Effectiveness of photodynamic therapy as an adjunct to topical antiviral therapy in the treatment of herpes labialis: A randomized controlled clinical trial
10.1016/j.pdpdt.2021.102302 · 2021 · External reference
Clinical study on the effectiveness of three products in the treatment of herpes simplex labialis
10.1038/s41598-020-63530-6 · 2020 · External reference
A pilot study of treatment of herpes labialis with 1072 nm narrow waveband light
10.1046/j.1365-2230.2001.00783.x · 2001 · External reference
Evaluation of the efficacy of low-level light therapy using 1072 nm infrared light for the treatment of herpes simplex labialis
10.1111/ced.12069 · 2013 · External reference
Unresolved reference
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Successful treatment of herpes labialis with topical acyclovir
10.1136/bmj.286.6379.1699 · 1983 · External reference
Treatment of recurrent herpes simplex labialis with topical butylated hydroxytoluene
10.1038/clpt.1985.134 · 1985 · External reference
A novel drug delivery system using acyclovir nanofiber patch for topical treatment of recurrent herpes labialis: a randomized clinical trial
10.1002/cre2.512 · 2022 · External reference
Topical foscarnet therapy in recurrent orolabial herpes simplex. Controlled clinical study on efficacy
1996 · External reference
Topical ether and herpes simplex labialis
1980 · External reference
Efficacy and tolerability of propolis special extract GH 2002 as a lip balm against herpes labialis: A randomized, double-blind three-arm dose-finding study
10.4236/health.2011.31010 · 2011 · External reference
Comparing the effect of diode laser against acyclovir cream for the treatment of herpes labialis
10.4317/jced.53679 · 2017 · External reference
Valacyclovir and topical clobetasol gel for the episodic treatment of herpes labialis: a patient-initiated, double-blind, placebo-controlled pilot trial
10.1111/j.1468-3083.2008.03047.x · 2009 · External reference
Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial
10.1111/j.1468-3083.2011.04269.x · 2012 · External reference
Evaluation of the efficacy and safety of a CS20® protective barrier gel containing OGT compared with topical aciclovir and placebo on functional and objective symptoms of labial herpes recurrences: a randomized clinical trial
10.1111/j.1468-3083.2011.04269.x · 2012 · External reference
Evaluation of Zovirax 5% cream in subjects with recurrent herpes labialis
2000 · External reference
Failure of lysine treatment in recurrent herpes simplex labialis
10.1016/s0140-6736(78)91658-6 · 1978 · External reference
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Oral acyclovir and herpes labialis: a randomized, double-blind, placebo-controlled study
10.14219/jada.archive.1987.0211 · 1987 · External reference
Herpes labialis treatment with acyclovir 5% modified aqueous cream: a double-blind randomized trial
10.1016/0030-4220(89)90007-8 · 1989 · External reference
Photodynamic therapy and acyclovir in the treatment of recurrent herpes labialis: A controlled randomized clinical trial
10.1016/j.pdpdt.2020.102093 · 2021 · External reference
Lip balm efficacy in the treatment of recurrent herpes labialis
10.1177/0022034590069s101 · 1990 · External reference
Treatment of recurrent herpes simplex labialis with levamisole
10.1128/aac.15.5.662 · 1979 · External reference
Clinical effect observation of Nd: YAG laser combined with acyclovir in the treatment of herpes labialis
10.12016/j.issn.2096⁃1456.2022.02.008 · 2022 · External reference
The effects of Herstat (3% propolis ointment ACF) application in cold sores: a double-blind placebo-controlled clinical trial
2001 · External reference
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Silica gel is as effective as acyclovir cream in patients with recurrent herpes labialis: results of a randomized, open-label trial
10.1080/09546630701593457 · 2008 · External reference
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A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine
2001 · External reference
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Comparative efficacy of antiviral agents for prevention and management of herpes labialis: a systematic review and network meta-analysis
10.1016/j.jebdp.2022.101778 · 2023 · External reference
Is low-level laser therapy effective in the treatment of herpes labialis? Systematic review and meta-analysis
10.1007/s10103-022-03653-6 · 2022 · External reference
Association of photodynamic therapy and photobiomodulation as a promising treatment of herpes labialis: a systematic review
10.1089/photob.2021.0186 · 2022 · External reference
Herpes virus, oral clinical signs and QoL: Systematic review of recent data
10.3390/v11050463 · 2019 · External reference
