Research graph
References from Metabolic Signatures for Liver Cancer Diagnosis and Mechanistic Insights: A Large‐Scale, Multicenter Study. Local targets link to admitted publications; unresolved targets remain external evidence.
The Lancet Commission on Addressing the Global Hepatocellular Carcinoma Burden: Comprehensive Strategies From Prevention to Treatment
10.1016/s0140-6736(25)01042-6 · 2025 · External reference
The Global, Regional, and National Burden of Cancer, 1990–2023, With Forecasts to 2050: A Systematic Analysis for the Global Burden of Disease Study 2023
10.1016/s0140-6736(25)01635-6 · 2025 · External reference
Cancer Survival Statistics in china 2019‐2021: A Multicenter, Population‐Based Study
2024 · External reference
Metabolic Rearrangements in Primary Liver Cancers: Cause and Consequences
10.1038/s41575-019-0217-8 · 2019 · External reference
Metabolic Reprogramming in the Tumor Microenvironment of Liver Cancer
10.1186/s13045-024-01527-8 · 2024 · External reference
Performance and Effectiveness of Hepatocellular Carcinoma Screening in Individuals With Hbsag Seropositivity in china: A Multicenter Prospective Study
10.1038/s43018-023-00618-8 · 2023 · External reference
Metabolomics in Cancer Research and Emerging Applications in Clinical Oncology
2021 · External reference
A Large‐Scale, Multicenter Serum Metabolite Biomarker Identification Study for the Early Detection of Hepatocellular Carcinoma
10.1002/hep.29561 · 2018 · External reference
Metabonomic Profiles Discriminate Hepatocellular Carcinoma From Liver Cirrhosis by Ultraperformance Liquid Chromatography–Mass Spectrometry
10.1021/pr2009252 · 2012 · External reference
Serum and Urine Metabolite Profiling Reveals Potential Biomarkers of Human Hepatocellular Carcinoma
10.1074/mcp.m110.004945 · 2011 · External reference
Power of Metabolomics in Diagnosis and Biomarker Discovery of Hepatocellular Carcinoma
10.1002/hep.26130 · 2013 · External reference
Plasma Metabolomic Profiling for Hepatocellular Carcinoma Diagnosis and Microvascular Invasion Prediction
10.1002/ijc.70055 · 2025 · External reference
Metabolomic Profiles for Hbv Related Hepatocellular Carcinoma Including Alpha‐fetoproteins Positive and Negative Subtypes
10.3389/fonc.2019.01069 · 2019 · External reference
Qcomics: Recommendations and Guidelines for Robust, Easily Implementable and Reportable Quality Control of Metabolomics Data
10.1021/acs.analchem.3c03660 · 2024 · External reference
Metabolic Signatures for Gastric Cancer Diagnosis and Mechanistic Insights: A Multicenter Study
10.1038/s44321-025-00325-0 · 2025 · External reference
GSTZ1‐1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone
10.15252/embj.2019101964 · 2019 · External reference
Longitudinal Change of Metabolite Profile and Its Relation to Multiple Risk Factors for the Risk of Developing Hepatitis B‐Related Hepatocellular Carcinoma
10.1002/mc.23255 · 2020 · External reference
Prediagnostic Plasma Metabolite Concentrations and Liver Cancer Risk: A Population‐Based Study of chinese Men
10.1016/j.ebiom.2024.104990 · 2024 · External reference
Loss of Carbamoyl Phosphate Synthetase 1 Potentiates Hepatocellular Carcinoma Metastasis by Reducing Aspartate Level
10.1002/advs.202402703 · 2024 · External reference
Regulation and Destabilization of HIF‐1α by ARD1‐Mediated Acetylation
10.1016/s0092-8674(02)01085-1 · 2002 · External reference
Hbx Mediated Increase of sirt1 Contributes to Hbv‐Related Hepatocellular Carcinoma Tumorigenesis
10.7150/ijms.43491 · 2020 · External reference
Nuclear Hbx Binds the Hbv Minichromosome and Modifies the Epigenetic Regulation of Cccdna Function
10.1073/pnas.0908365106 · 2009 · External reference
Sirtuin 1 Regulates hepatitis b Virus Transcription and Replication by Targeting Transcription Factor Ap‐1
10.1128/jvi.02861-13 · 2014 · External reference
α‐Fetoprotein, Des‐γ Carboxyprothrombin, and Lectin‐Bound α‐Fetoprotein in Early Hepatocellular Carcinoma
10.1053/j.gastro.2009.04.005 · 2009 · External reference
Afp‐l3 for the Diagnosis of Early Hepatocellular Carcinoma: A Meta‐Analysis
10.1097/md.0000000000027673 · 2021 · External reference
The Performance of afp, afp‐3, dcp as Biomarkers for Detection of Hepatocellular Carcinoma (hcc): A Phase 3 Biomarker Study in the united states
10.1016/j.cgh.2022.01.047 · 2023 · External reference
The Detection of Hepatocellular Carcinoma Using a Prospectively Developed and Validated Model Based on Serological Biomarkers
10.1158/1055-9965.epi-13-0870 · 2014 · External reference
Role of the Galad and Balad‐2 Serologic Models in Diagnosis of Hepatocellular Carcinoma and Prediction of Survival in Patients
10.1016/j.cgh.2015.12.042 · 2016 · External reference
Novel Biomarkers for Early Detection of Hepatocellular Carcinoma
10.3390/diagnostics14202278 · 2024 · External reference
Lung Cancer Scrna‐seq and Lipidomics Reveal Aberrant Lipid Metabolism for Early‐Stage Diagnosis
10.1126/scitranslmed.abk2756 · 2022 · External reference
Integrative Plasma and Fecal Metabolomics Identify Functional Metabolites in Adenoma‐Colorectal Cancer Progression and as Early Diagnostic Biomarkers
10.1016/j.ccell.2024.07.005 · 2024 · External reference
A Sustainable Approach to Universal Metabolic Cancer Diagnosis
10.1038/s41893-024-01323-9 · 2024 · External reference
Integrative Metabolomic Characterisation Identifies Altered Portal Vein Serum Metabolome Contributing to human Hepatocellular Carcinoma
10.1136/gutjnl-2021-325189 · 2022 · External reference
Discovery of a Carbamoyl Phosphate Synthetase 1–Deficient HCC Subtype With Therapeutic Potential Through Integrative Genomic and Experimental Analysis
10.1002/hep.32088 · 2021 · External reference
Loss of Bcaa Catabolism During Carcinogenesis Enhances mtorc1 Activity and Promotes Tumor Development and Progression
10.1016/j.cmet.2018.12.020 · 2019 · External reference
The Effect of Green Green Tea Consumption on Body Mass Index, Lipoprotein, Liver Enzymes, and Liver Cancer: An Updated Systemic Review Incorporating a Meta‐analysis
10.1080/10408398.2022.2113360 · 2024 · External reference
Coffee Drinking and Reduced Risk of Liver Cancer: Update on Epidemiological Findings and Potential Mechanisms
10.1007/s13668-019-0274-1 · 2019 · External reference
Coffee Consumption by Type and Risk of Digestive Cancer: A Large Prospective Cohort Study
10.1038/s41416-019-0465-y · 2019 · External reference
Tea Consumption and Liver Cancer: A Population‐based Case‐Control Study in Eastern china
10.3390/nu17162647 · 2025 · External reference
Nicotinamide for Skin‐cancer Chemoprevention in Transplant Recipients
10.1056/nejmoa2203086 · 2023 · External reference
Nicotinamide Is an Inhibitor of sirt1 in Vitro, but Can be a Stimulator in Cells
10.1007/s00018-017-2527-8 · 2017 · External reference
Emerging Roles and the Regulation of Aerobic Glycolysis in Hepatocellular Carcinoma
10.1186/s13046-020-01629-4 · 2020 · External reference
Orange: Data Mining Toolbox in Python
2013 · External reference
Efficient Plasma Metabolic Fingerprinting as a Novel Tool for Diagnosis and Prognosis of Gastric Cancer: A Large‐scale, Multicentre Study
10.1136/gutjnl-2023-330045 · 2023 · External reference
Genomic Atlas of the Plasma Metabolome Prioritizes Metabolites Implicated in human Diseases
10.1038/s41588-022-01270-1 · 2023 · External reference
Diversity and Scale: Genetic Architecture of 2068 Traits in the va million Veteran Program
10.1126/science.adj1182 · 2024 · External reference
Instrumental Variable Estimation of Causal Risk Ratios and Causal Odds Ratios in Mendelian Randomization Analyses
10.1093/aje/kwr026 · 2011 · External reference
10.1093/ije/dyv080
10.1093/ije/dyv080 · External reference
Assessing the Suitability of Summary Data for Two‐Sample Mendelian Randomization Analyses Using MR‐Egger Regression: The Role of the I2 Statistic
2016 · External reference
Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
10.1002/gepi.21758 · 2013 · External reference
Immunodetection of Proteins by Western Blotting
1992 · External reference
Sample Size Determinationfor Diagnostic Accuracy Studies Involving Binormal Roc Curve Indices
10.1002/(sici)1097-0258(19970715)16:13<1529::aid-sim565>3.0.co;2-h · 1997 · External reference