Research graph
References from Improved Method for Obtaining Patient‐Derived Glioblastoma Organoid and Primary Cells: A Generic and Simplified Approach for Intracranial Tumor With Minimized Input. Local targets link to admitted publications; unresolved targets remain external evidence.
Glioblastoma and Other Primary Brain Malignancies in Adults
10.1001/jama.2023.0023 · 2023 · External reference
Survival in Glioblastoma: A Review on the Impact of Treatment Modalities
10.1007/s12094-016-1497-x · 2016 · External reference
Malignant Astrocytic Glioma: Genetics, Biology, and Paths to Treatment
10.1101/gad.1596707 · 2007 · External reference
Current Trends in the Surgical Management and Treatment of Adult Glioblastoma
2015 · External reference
High‐Grade Glioma: ESMO Clinical Practice Guidelines for Diagnosis, Treatment and Follow‐Up
10.1093/annonc/mdu050 · 2014 · External reference
The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma
10.3390/cells10030484 · 2021 · External reference
Reciprocal Signaling Between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
10.1016/j.stem.2018.03.011 · 2018 · External reference
Hypoxia and Metabolism. Hypoxia, DNA Repair and Genetic Instability
10.1038/nrc2344 · 2008 · External reference
U‐251 Revisited: Genetic Drift and Phenotypic Consequences of Long‐Term Cultures of Glioblastoma Cells
10.1002/cam4.219 · 2014 · External reference
Patient‐Derived Tumour Xenografts as Models for Oncology Drug Development
10.1038/nrclinonc.2012.61 · 2012 · External reference
Challenges to Curing Primary Brain Tumours
10.1038/s41571-019-0177-5 · 2019 · External reference
Genetically Engineered Cerebral Organoids Model Brain Tumor Formation
10.1038/s41592-018-0070-7 · 2018 · External reference
Organogenesis in a Dish: Modeling Development and Disease Using Organoid Technologies
10.1126/science.1247125 · 2014 · External reference
Cerebral Organoids Model Human Brain Development and Microcephaly
10.1038/nature12517 · 2013 · External reference
Functional Cortical Neurons and Astrocytes From Human Pluripotent Stem Cells in 3D Culture
10.1038/nmeth.3415 · 2015 · External reference
Brain‐Region‐Specific Organoids Using Mini‐Bioreactors for Modeling ZIKV Exposure
10.1016/j.cell.2016.04.032 · 2016 · External reference
Organoids in Cancer Research
10.1038/s41568-018-0007-6 · 2018 · External reference
Progress and Potential in Organoid Research
10.1038/s41576-018-0051-9 · 2018 · External reference
Glioma Cancer Stem Cells Secrete Gremlin1 to Promote Their Maintenance Within the Tumor Hierarchy
10.1101/gad.235515.113 · 2014 · External reference
Glioblastoma Model Using Human Cerebral Organoids
10.1016/j.celrep.2018.03.105 · 2018 · External reference
Modeling Patient‐Derived Glioblastoma With Cerebral Organoids
10.1016/j.celrep.2019.02.063 · 2019 · External reference
Designer Matrices for Intestinal Stem Cell and Organoid Culture
10.1038/nature20168 · 2016 · External reference
Modeling Development and Disease With Organoids
10.1016/j.cell.2016.05.082 · 2016 · External reference
A Three‐Dimensional Organoid Culture System Derived From Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
10.1158/0008-5472.can-15-2402 · 2016 · External reference
The Brain Tumor Microenvironment
10.1002/glia.21264 · 2012 · External reference
Organoid Modeling of the Tumor Immune Microenvironment
10.1016/j.cell.2018.11.021 · 2018 · External reference
A Human Co‐Culture Cell Model Incorporating Microglia Supports Glioblastoma Growth and Migration, and Confers Resistance to Cytotoxics
10.1096/fj.201901858rr · 2020 · External reference
Astrocytes Enhance Glioblastoma Growth
10.1002/glia.23718 · 2020 · External reference
Pre‐Clinical Drug Testing in 2D and 3D Human In Vitro Models of Glioblastoma Incorporating Non‐Neoplastic Astrocytes: Tunneling Nano Tubules and Mitochondrial Transfer Modulates Cell Behavior and Therapeutic Response
10.3390/ijms20236017 · 2019 · External reference
A Patient‐Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter‐ and Intra‐Tumoral Heterogeneity
10.1016/j.cell.2019.11.036 · 2020 · External reference
Brain and Other Central Nervous System Tumor Statistics, 2021
2021 · External reference
Human Organoids: Model Systems for Human Biology and Medicine
10.1038/s41580-020-0259-3 · 2020 · External reference
Modeling Nervous System Tumors With Human Stem Cells and Organoids
10.1186/s13619-022-00150-7 · 2023 · External reference
Glioma Stem Cells Promote Radioresistance by Preferential Activation of the DNA Damage Response
10.1038/nature05236 · 2006 · External reference
Biomarkers for Glioma Immunotherapy: The Next Generation
10.1007/s11060-015-1746-9 · 2015 · External reference
Tackling the Many Facets of Glioblastoma Heterogeneity
10.1016/j.stem.2020.02.005 · 2020 · External reference
A Novel Integrated System Using Patient‐Derived Glioma Cerebral Organoids and Xenografts for Disease Modeling and Drug Screening
10.1016/j.canlet.2020.12.013 · 2021 · External reference
Patient‐Derived Tumor Organoids as a Platform of Precision Treatment for Malignant Brain Tumors
10.1038/s41598-022-20487-y · 2022 · External reference
Protocol for Derivation of Organoids and Patient‐Derived Orthotopic Xenografts from Glioma Patient Tumors
10.1016/j.xpro.2021.100534 · 2021 · External reference
Brain Tumoroids: Treatment Prediction and Drug Development for Brain Tumors With Fast, Reproducible, and Easy‐to‐Use Personalized Models
10.1093/neuonc/noae184 · 2025 · External reference
Establishment of Patient‐Derived Organoid Models of Lower‐Grade Glioma
10.1093/neuonc/noab273 · 2022 · External reference
Individualized Patient Tumor Organoids Faithfully Preserve Human Brain Tumor Ecosystems and Predict Patient Response to Therapy
10.1016/j.stem.2025.01.002 · 2025 · External reference
Patient‐Derived Tumor Organoid Predicts Drugs Response in Glioblastoma: A Step Forward in Personalized Cancer Therapy?
10.1016/j.jocn.2020.04.107 · 2020 · External reference
Engineering of Human Brain Organoids With a Functional Vascular‐Like System
10.1038/s41592-019-0586-5 · 2019 · External reference
Generation of Human Vascularized Brain Organoids
10.1097/wnr.0000000000001014 · 2018 · External reference
