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References from Breath Signatures of Antiseizure Medication Response and Tolerability in Adults With Epilepsy. Local targets link to admitted publications; unresolved targets remain external evidence.
Difficulties in Treatment and Management of Epilepsy and Challenges in New Drug Development
10.3390/ph3072090 · 2010 · External reference
Overview of Therapeutic Drug Monitoring
10.3904/kjim.2009.24.1.1 · 2009 · External reference
Host Factors Affecting Antiepileptic Drug Delivery‐Pharmacokinetic Variability
10.1016/j.addr.2011.10.003 · 2012 · External reference
Antiepileptic Drug Treatment in Pregnancy: Changes in Drug Disposition and Their Clinical Implications
10.1111/epi.12109 · 2013 · External reference
Oral Contraceptives Induce Lamotrigine Metabolism: Evidence From a Double‐Blind, Placebo‐Controlled Trial
10.1111/j.1528-1167.2007.00997.x · 2007 · External reference
Clinical Utility of Therapeutic Drug Monitoring of Antiepileptic Drugs: Systematic Review
2020 · External reference
Pharmacological Aspects of Antiseizure Medications: From Basic Mechanisms to Clinical Considerations of Drug Interactions and Use of Therapeutic Drug Monitoring
10.1002/epd2.20069 · 2023 · External reference
Correlation of Levetiracetam Concentration in Peripheral Blood Mononuclear Cells With Clinical Efficacy: A Sensitive Monitoring Biomarker in Patients With Epilepsy
10.1016/j.seizure.2020.03.009 · 2020 · External reference
Therapeutic Drug Monitoring of Lacosamide Among Children: Is It Helpful?
10.3389/fphar.2023.1164902 · 2023 · External reference
New Perspectives on ‘Breathomics’: Metabolomic Profiling of Non‐Volatile Organic Compounds in Exhaled Breath Using DI‐FT‐ICR‐MS
10.1038/s42003-024-05943-x · 2024 · External reference
Breath Analysis for Medical Diagnosis and Therapeutic Monitoring
2005 · External reference
Pharmacometabolomics via Real‐Time Breath Analysis Captures Metabotypes of Asthmatic Children Associated With Salbutamol Responsiveness
10.1016/j.isci.2024.111446 · 2024 · External reference
Acetazolamide: Old Drug, New Evidence?
10.1002/epi4.12619 · 2022 · External reference
Valproate Inhibits Mitochondrial Bioenergetics and Increases Glycolysis in Saccharomyces cerevisiae
10.1038/s41598-020-68725-5 · 2020 · External reference
Personalised Therapeutic Management of Epileptic Patients Guided by Pathway‐Driven Breath Metabolomics
10.1038/s43856-021-00021-3 · 2021 · External reference
Basal Ganglia Involvement in Temporal Lobe Epilepsy: A Functional and Morphologic Study
10.1212/01.wnl.0000297514.47695.48 · 2008 · External reference
NMR‐Based Metabolomics in Pediatric Drug Resistant Epilepsy – Preliminary Results
10.1038/s41598-019-51337-z · 2019 · External reference
Metabolomics as a Tool for the Characterization of Drug‐Resistant Epilepsy
10.3389/fneur.2017.00459 · 2017 · External reference
The Role of Dopamine Signaling in Epileptogenesis
10.3389/fncel.2013.00157 · 2013 · External reference
Monoamines and Their Metabolites in Cerebrospinal Fluid and Temporal Cortex of Epileptic Patients
10.1016/0920-1211(96)00030-7 · 1996 · External reference
Involvement of the Basal Ganglia in Refractory Epilepsy: An 18F‐Fluoro‐L‐DOPA PET Study Using 2 Methods of Analysis
2005 · External reference
Monoamine Metabolites in the CSF of Epileptic Patients
10.1212/wnl.29.8.1157 · 1979 · External reference
Secondary Neurotransmitter Deficiencies in Epilepsy Caused by Voltage‐Gated Sodium Channelopathies: A Potential Treatment Target?
10.1016/j.ymgme.2015.11.008 · 2016 · External reference
RNA‐Seq Analysis of Hippocampal Tissues Reveals Novel Candidate Genes for Drug Refractory Epilepsy in Patients With MTLE‐HS
10.1016/j.ygeno.2016.04.001 · 2016 · External reference
The Metabolic Basis of Epilepsy
10.1038/s41582-022-00651-8 · 2022 · External reference
The Effect of Antiepileptic Drugs on Mitochondrial Activity: A Pilot Study
10.1177/0883073809352888 · 2010 · External reference
Impairments in Oxidative Glucose Metabolism in Epilepsy and Metabolic Treatments Thereof
10.3389/fncel.2018.00274 · 2018 · External reference
Mitochondria and Oxidative Stress in Epilepsy: Advances in Antioxidant Therapy
2025 · External reference
Effects of Antiepileptic Drugs on Mitochondrial Functions, Morphology, Kinetics, Biogenesis, and Survival
10.1016/j.eplepsyres.2017.07.003 · 2017 · External reference
Metabolic Concerns Associated With Antiepileptic Medications
2004 · External reference
Carnitine in the Treatment of Valproic Acid‐Induced Toxicity
10.1080/15563650902752376 · 2009 · External reference
Kynurenine Pathway of Tryptophan Metabolism in Neuropsychiatric Disorders: Pathophysiologic and Therapeutic Considerations
10.9758/cpn.2020.18.4.507 · 2020 · External reference
Branched‐Chain Amino Acids and Brain Metabolism
10.1007/s11064-017-2261-5 · 2017 · External reference
Psychiatric and Cognitive Aspects of Phenylketonuria: The Limitations of Diet and Promise of New Treatments
10.3389/fpsyt.2019.00561 · 2019 · External reference
Insights From Animal Models on the Pathophysiology of Hyperphenylalaninemia: Role of Mitochondrial Dysfunction, Oxidative Stress and Inflammation
10.1007/s12035-021-02304-1 · 2021 · External reference
The Role of Mitochondria in Mood Disorders: From Physiology to Pathophysiology and to Treatment
10.3389/fpsyt.2021.546801 · 2021 · External reference
GABA and Glutamate in the Human Brain
10.1177/1073858402238515 · 2002 · External reference
Aerobic Glycolysis in the Human Brain Is Associated With Development and Neotenous Gene Expression
10.1016/j.cmet.2013.11.020 · 2014 · External reference
Identification of Gene Regulatory Networks Affected Across Drug‐Resistant Epilepsies
10.1038/s41467-024-46592-2 · 2024 · External reference
Taking Your Breath Away: Metabolomics Breathes Life in to Personalized Medicine
10.1016/j.tibtech.2014.08.003 · 2014 · External reference
The Potential of Metabolomics in Biomedical Applications
10.3390/metabo12020194 · 2022 · External reference
The Human Volatilome: Volatile Organic Compounds (VOCs) in Exhaled Breath, Skin Emanations, Urine, Feces and Saliva
10.1088/1752-7155/8/3/034001 · 2014 · External reference