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References from Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking. Local targets link to admitted publications; unresolved targets remain external evidence.
Cognitive Deficits in Bipolar Disorders: Implications for Emotion
10.1016/j.cpr.2017.11.006 · 2018 · External reference
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 Guidelines for the Management of Patients With Bipolar Disorder
10.1111/bdi.12609 · 2018 · External reference
Suicidality in Bipolar Compared to Unipolar Depressed Inpatients
10.1007/s004060070016 · 2000 · External reference
Prevalence of Suicide Attempts in Bipolar Disorder: A Systematic Review and Meta‐Analysis of Observational Studies
10.1017/s2045796019000593 · 2019 · External reference
Annual Costs of Bipolar Disorders in Germany
2004 · External reference
The Economic Burden of Bipolar Disorder in the United States: A Systematic Literature Review
10.2147/ceor.s259338 · 2020 · External reference
Bipolar Affective Disorder, Lithium Carbonate and ca++ ATPase
10.1016/0165-0327(81)90032-x · 1981 · External reference
Cognitive Impairment in Patients With Bipolar Disorder: Impact of Pharmacological Treatment
10.1007/s40263-019-00688-2 · 2020 · External reference
A Review for Lithium: Pharmacokinetics, Drug Design, and Toxicity
10.2174/1871527318666191114095249 · 2019 · External reference
Extrapyramidal Side Effects With Atypical Neuroleptics in Bipolar Disorder
10.1016/j.pnpbp.2005.10.014 · 2006 · External reference
Disturbed Calcium Metabolism in a Patient With Bipolar Disorder and Impaired Renal Function
10.1093/ndt/gfh797 · 2005 · External reference
A Population‐Based Heritability Estimate of Bipolar Disorder In a Swedish Twin Sample
10.1016/j.psychres.2019.06.010 · 2019 · External reference
Twin Studies for the Investigation of the Relationships Between Genetic Factors and Brain Abnormalities in Bipolar Disorder
10.1017/s2045796016000615 · 2016 · External reference
Modeling Protein‐Protein Interactions in Axon Initial Segment to Understand Their Potential Impact on Action Potential Initiation
10.4103/1673-5374.295332 · 2021 · External reference
Translational Genomics and Beyond in Bipolar Disorder
10.1038/s41380-020-0782-9 · 2021 · External reference
The Axon Initial Segment: An Updated Viewpoint
10.1523/jneurosci.1922-17.2018 · 2018 · External reference
Rare Variants in Neuronal Excitability Genes Influence Risk for Bipolar Disorder
10.1073/pnas.1424958112 · 2015 · External reference
Genetic Disruption of Ankyrin‐G in Adult Mouse Forebrain Causes Cortical Synapse Alteration and Behavior Reminiscent of Bipolar Disorder
10.1073/pnas.1700689114 · 2017 · External reference
Usage Patterns of Traditional Chinese Medicine for Patients With Bipolar Disorder: A Population‐Based Study in Taiwan
10.3390/healthcare12040490 · 2024 · External reference
TCMSP: A Database of Systems Pharmacology for Drug Discovery From Herbal Medicines
10.1186/1758-2946-6-13 · 2014 · External reference
UniProt: The Universal Protein Knowledgebase in 2021
2021 · External reference
Cytoscape Automation: Empowering Workflow‐Based Network Analysis
10.1186/s13059-019-1758-4 · 2019 · External reference
OMIM.Org: Online Mendelian Inheritance in Man (OMIM(R)), an Online Catalog of Human Genes and Genetic Disorders
10.1093/nar/gku1205 · 2015 · External reference
GeneCards Version 3: The Human Gene Integrator
10.1093/database/baq020 · 2010 · External reference
DrugBank 5.0: A Major Update to the DrugBank Database for 2018
10.1093/nar/gkx1037 · 2018 · External reference
Therapeutic Target Database Update 2022: Facilitating Drug Discovery With Enriched Comparative Data of Targeted Agents
10.1093/nar/gkab953 · 2022 · External reference
The DisGeNET Knowledge Platform for Disease Genomics: 2019 Update
2020 · External reference
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10.1093/nar/gky1131 · 2019 · External reference
Metascape Provides a Biologist‐Oriented Resource for the Analysis of Systems‐Level Datasets
10.1038/s41467-019-09234-6 · 2019 · External reference
RCSB Protein Data Bank: Enabling Biomedical Research and Drug Discovery
10.1002/pro.3730 · 2020 · External reference
AutoDock Vina: Improving the Speed and Accuracy of Docking With a New Scoring Function, Efficient Optimization, and Multithreading
10.1002/jcc.21334 · 2010 · External reference
Xiaoyaosan Improves Antibiotic‐Induced Depressive‐Like and Anxiety‐Like Behavior in Mice Through Modulating the Gut Microbiota and Regulating the NLRP3 Inflammasome in the Colon
10.3389/fphar.2021.619103 · 2021 · External reference
Gut Dysbiosis Induces the Development of Depression‐Like Behavior Through Abnormal Synapse Pruning in Microglia‐Mediated by Complement C3
10.1186/s40168-024-01756-6 · 2024 · External reference
The ANK3 Bipolar Disorder Gene Regulates Psychiatric‐Related Behaviors That Are Modulated by Lithium and Stress
10.1016/j.biopsych.2012.10.016 · 2013 · External reference
An Integrated Pharmacology‐Based Analysis for Antidepressant Mechanism of Chinese Herbal Formula Xiao‐Yao‐San
10.3389/fphar.2020.00284 · 2020 · External reference
A Standardized Protocol for Repeated Social Defeat Stress in Mice
10.1038/nprot.2011.361 · 2011 · External reference
Activation of BDNF by Transcription Factor Nrf2 Contributes to Antidepressant‐Like Actions in Rodents
10.1038/s41398-021-01261-6 · 2021 · External reference
Traditional Chinese Medicine Network Pharmacology: Theory, Methodology and Application
10.1016/s1875-5364(13)60037-0 · 2013 · External reference
Bioactive Compounds From Huashi Baidu Decoction Possess Both Antiviral and Anti‐Inflammatory Effects Against COVID‐19
10.1073/pnas.2301775120 · 2023 · External reference
Exploring the Efficacious Constituents and Underlying Mechanisms of Sini Decoction for Sepsis Treatment Through Network Pharmacology and Multi‐Omics
10.1016/j.phymed.2023.155212 · 2024 · External reference
Antidepressant Effects of the Traditional Chinese Herbal Formula Xiao‐Yao‐San and Its Bioactive Ingredients
10.1016/j.phymed.2022.154558 · 2023 · External reference
Corrigendum to ‘Carthami Flos Extract Against Carbon Tetrachloride‐Induced Liver Fibrosis via Alleviating Angiogenesis in Mice’ Volume 108
10.1016/j.phymed.2023.154719 · 2024 · External reference
The Potential of Flavonoids and Flavonoid Metabolites in the Treatment of Neurodegenerative Pathology in Disorders of Cognitive Decline
10.3390/antiox12030663 · 2023 · External reference
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review
10.3389/fphar.2020.565700 · 2020 · External reference
Advance in the Pharmacological Effects of Quercetin in Modulating Oxidative Stress and Inflammation Related Disorders
10.1002/ptr.7966 · 2023 · External reference
Beta‐Sitosterol as a Promising Anticancer Agent for Chemoprevention and Chemotherapy: Mechanisms of Action and Future Prospects
10.1016/j.advnut.2023.05.013 · 2023 · External reference
Stress, Serotonin, and Hippocampal Neurogenesis in Relation to Depression and Antidepressant Effects
10.1016/j.neubiorev.2013.11.009 · 2014 · External reference
Distinct Proteomic, Transcriptomic, and Epigenetic Stress Responses in Dorsal and Ventral Hippocampus
10.1016/j.biopsych.2018.02.003 · 2018 · External reference
Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder
10.1016/j.biopsych.2019.09.018 · 2020 · External reference
Mapping the Scientific Research on Bipolar Disorder: A Scientometric Study of Hotspots, Bursts, and Trends
10.1016/j.jad.2023.08.069 · 2023 · External reference
Effects and Mechanisms of Xiaochaihu Tang Against Liver Fibrosis: An Integration of Network Pharmacology, Molecular Docking and Experimental Validation
10.1016/j.jep.2022.116053 · 2023 · External reference
Exploring the Mechanism of Buxue Yimu Pill on Hemorrhagic Anemia Through Molecular Docking, Network Pharmacology and Experimental Validation
10.1016/s1875-5364(21)60104-8 · 2021 · External reference
Inflammatory Signaling Mechanisms in Bipolar Disorder
10.1186/s12929-021-00742-6 · 2021 · External reference
The Differential Levels of Inflammatory Cytokines and BDNF Among Bipolar Spectrum Disorders
10.1093/ijnp/pyw012 · 2016 · External reference
Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient‐Derived Astrocytes
10.1016/j.stemcr.2021.02.004 · 2021 · External reference
Nrf2‐SHP Cascade‐Mediated STAT3 Inactivation Contributes to AMPK‐Driven Protection Against Endotoxic Inflammation
10.3389/fimmu.2020.00414 · 2020 · External reference
Liver‐Specific siRNA‐Mediated Stat3 or C3 Knockdown Improves the Outcome of Experimental Autoimmune Myocarditis
10.1016/j.omtm.2020.05.023 · 2020 · External reference
Targeting STAT3 Signaling in COL1+ Fibroblasts Controls Colitis‐Associated Cancer in Mice
10.3390/cancers14061472 · 2022 · External reference
ISOC1 Modulates Inflammatory Responses in Macrophages Through the AKT1/PEX11B/Peroxisome Pathway
10.3390/molecules27185896 · 2022 · External reference
IL‐6 in Inflammation, Autoimmunity and Cancer
10.1093/intimm/dxaa078 · 2021 · External reference
Network Pharmacology Prediction and Molecular Docking‐Based Strategy to Discover the Potential Pharmacological Mechanism of Huai Hua San Against Ulcerative Colitis
10.2147/dddt.s319786 · 2021 · External reference