Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Silymarin Protects Against Daunorubicin‐Induced DNA Damage in an In Vivo Comet Assay. Local targets link to admitted publications; unresolved targets remain external evidence.
Time‐Dependent Response of Daunorubicin on Cytotoxicity, Cell Cycle, and DNA Repair in Acute Lymphoblastic Leukaemia
10.1186/s12885-019-5377-y · 2019 · External reference
Improving Prediction of Blood Cancer Using Leukemia Microarray Gene Data and Chi2 Features With a Weighted Convolutional Neural Network
10.1038/s41598-024-65315-7 · 2024 · External reference
10.5772/intechopen.91507
10.5772/intechopen.91507 · 2021 · External reference
DNA Repair: Monitoring by the Comet Assay
2009 · External reference
10.5812/mejrh‐141053
10.5812/mejrh‐141053 · External reference
Therapy‐Related Myelodysplasia and Acute Myeloid Leukemia
2013 · External reference
Effect of the Flavanolignans of Silybum marianum L. on Lipid Peroxidation in Rat Liver Microsomes and Freshly Isolated Hepatocytes
10.1016/1043-6618(92)91383-r · 1992 · External reference
Fourth International Workgroup on Genotoxicity Testing: Results of the In Vivo Comet Assay Workgroup
10.1016/j.mrgentox.2006.08.011 · 2007 · External reference
Silybin Dihemisuccinate Protects Against Glutathione Depletion and Lipid Peroxidation Induced by Acetaminophen in the Rat Liver
10.1055/s-2006-962055 · 2008 · External reference
Protective Effects of Silymarin Against Doxorubicin‐Induced Toxicity
2011 · External reference
Measuring DNA Modifications With the Comet Assay: A Compendium of Protocols
10.1038/s41596-022-00754-y · 2023 · External reference
Oxidative DNA Damage, Antioxidants, and Cancer
10.1002/(sici)1521-1878(199903)21:3<238::aid-bies8>3.0.co;2-3 · 1999 · External reference
Controlling Variation in the Comet Assay
10.3389/fgene.2014.00359 · 2014 · External reference
Role of Hydrogen Peroxide and Hydroxyl Radical Formation in the Killing of Ehrlich Tumor Cells by Anticancer Quinones
10.1073/pnas.83.12.4514 · 1986 · External reference
Unresolved reference
2018 · External reference
Mapping Genes That Contribute to Daunorubicin‐Induced Cytotoxicity
10.1158/0008-5472.can-06-4431 · 2007 · External reference
Protection Against Oxidative Damage of Erythrocyte Membrane by Silymarin
2001 · External reference
Unresolved reference
2018 · External reference
10.5772/35079
10.5772/35079 · 2012 · External reference
10.1002/9780470571224
10.1002/9780470571224 · 2010 · External reference
A Critical Evaluation of the Mechanisms of Action Proposed for the Antitumor Effects of the Anthracycline Antibiotics Adriamycin and Daunorubicin
10.1016/s0006-2952(98)00307-4 · 1999 · External reference
Biochemistry of Multidrug Resistance Mediated by the Multidrug Transporter
10.1146/annurev.bi.62.070193.002125 · 1993 · External reference
Antineoplastic Drugs and Their Analysis: A State‐Of‐The‐Art Review
10.1039/c7an00367f · 2017 · External reference
Use of Human Peripheral Blood Lymphocytes to Measure DNA‐Binding Capacity of Chemical Carcinogens
10.1073/pnas.85.10.3513 · 1988 · External reference
An Emerging Trend of Rapid Increase of Leukemia, but Not All Cancers, in the Aging Population in the United States
10.1038/s41598-019-48445-1 · 2019 · External reference
An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes Through Antioxidant Response Elements
10.1006/bbrc.1997.6943 · 1997 · External reference
Silymarin and Skin Cancer Prevention: Anti‐Inflammatory, Antioxidant, and Immunomodulatory Effects
2005 · External reference
Silymarin and Epithelial Cancer Chemoprevention: How Close Are We to Bedside?
10.1016/j.taap.2006.11.011 · 2007 · External reference
Effect of the Anticancer Drug Doxorubicin (Adriamycin) on Antioxidant Studies and Ultrastructural Investigation in the Liver, Kidney, and Heart Tissues of Male Rats
10.13005/bbra/3089 · 2023 · External reference
Milk Thistle Nomenclature: Why It Matters in Cancer Research and Pharmacokinetic Studies
10.1177/1534735407301825 · 2007 · External reference
The Current Situation and Future Trend of Leukemia Mortality by Sex and Area in China
10.3389/fpubh.2020.598215 · 2020 · External reference
Silybin and the Liver: From Basic Research to Clinical Practice
10.3748/wjg.v17.i18.2288 · 2011 · External reference
Acute Myeloid Leukemia
10.1056/nejm199909303411407 · 1999 · External reference
Anti‐Cancer Alternative Therapies: From Inorganic Nanoparticles to Tumor‐Killing Bacteria
10.25083/rbl/27.2/3416.3421 · 2022 · External reference
High Micronucleus Frequency in Peripheral Blood Lymphocytes of Untreated Cancer Patients Irrespective of Gender, Smoking, and Cancer Sites
10.1620/tjem.220.115 · 2010 · External reference
Minimum Information for Reporting on the Comet Assay (MIRCA): Recommendations for Describing Comet Assay Procedures and Results
10.1038/s41596-020-0398-1 · 2020 · External reference
10.20944/preprints202105.0429.v1
10.20944/preprints202105.0429.v1 · External reference
Association of Chemotherapy for Solid Tumors With Development of Therapy‐Related Myelodysplasia and Acute Myeloid Leukemia in the Modern Era
2013 · External reference
Nrf2‐Keap1 Defines a Physiologically Important Stress Response Mechanism
10.1016/j.molmed.2004.09.003 · 2004 · External reference
Effect of Silimarin (Legalon) Therapy on the Antioxidant Defense Mechanism and Lipid Peroxidation in Alcoholic Liver Disease (Double Blind Protocol)
1990 · External reference
The Use of Isolated Peripheral Lymphocytes and Human Whole Blood in the Comet Assay
10.1038/protex.2016.076 · 2016 · External reference
Targeting DNA Topoisomerase II in Cancer Chemotherapy
10.1038/nrc2607 · 2009 · External reference
10.1787/9789264264885-en
10.1787/9789264264885-en · 2016 · External reference
Classification of Anticancer Drugs: An Update With FDA‐ and EMA‐Approved Drugs
10.1007/s10555-024-10188-5 · 2024 · External reference
Antioxidant Activity of Silybin In Vivo During Long‐Term Iron Overload in Rats
2002 · External reference
DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
10.1016/j.chembiol.2010.04.012 · 2010 · External reference
Treatment of Acute Lymphoblastic Leukemia
10.1056/nejmra052603 · 2006 · External reference
Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents
10.5530/pres.16.4.82 · 2024 · External reference
A Comprehensive Review on Unravelling the Complexity of Blood Cancer
2024 · External reference
The Use of Silymarin in the Treatment of Liver Diseases
10.2165/00003495-200161140-00003 · 2001 · External reference
Silymarin as a Phytopharmaceutical Agent: Advances in Mechanistic Insights, Formulation Strategies, and Pre‐Clinical Applications
10.3389/fphar.2025.1711653 · 2025 · External reference
Differences in the Disposition of Silymarin Between Patients With Nonalcoholic Fatty Liver Disease and Chronic Hepatitis C
10.1124/dmd.111.040212 · 2011 · External reference
Unresolved reference
2020 · External reference
Doxorubicin‐Induced Cardiomyopathy
10.1056/nejm199809243391307 · 1998 · External reference
Mechanisms of Action of Silibinin in Cancer Chemoprevention
2006 · External reference
Anthracycline‐Induced Cardiotoxicity and Renin‐Angiotensin‐Aldosterone System: From Molecular Mechanisms to Therapeutic Applications
10.1007/s10741-020-09977-1 · 2022 · External reference
Congestive Heart Failure in Patients Treated With Doxorubicin: A Retrospective Analysis of Three Trials
10.1002/cncr.11407 · 2003 · External reference
Single Cell Gel/Comet Assay: Guidelines for In Vitro and In Vivo Genetic Toxicology Testing
10.1002/(sici)1098-2280(2000)35:3<206::aid-em8>3.0.co;2-j · 2000 · External reference
Chronic Liver Disease and Silymarin: A Biochemical and Clinical Review
10.14218/jcth.2020.00012 · 2020 · External reference
Synergistic Anti‐Cancer Effects of Silibinin With Conventional Cytotoxic Agents Doxorubicin, Cisplatin, and Carboplatin Against Human Breast Carcinoma MCF‐7 and MDA‐MB468 Cells
2002 · External reference
Antioxidant Properties of the Flavonoids Silybin and (+)‐Cyanidanol‐3: Comparison With Butylated Hydroxyanisole and Butylated Hydroxytoluene
10.1055/s-2007-969247 · 1986 · External reference
Hepatoprotective Effect of Silymarin
10.4254/wjh.v6.i3.144 · 2014 · External reference
Mechanistic Insights Into the Pharmacological Significance of Silymarin
10.3390/molecules27165327 · 2022 · External reference