Research graph
References from Scn1a ‐mediated developmental regulation of prefrontal cortex plasticity and cognition. Local targets link to admitted publications; unresolved targets remain external evidence.
Sodium channelopathies of skeletal muscle and brain
10.1152/physrev.00025.2020 · 2021 · External reference
Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy
10.1038/nn1754 · 2006 · External reference
Sodium channelopathies in neurodevelopmental disorders
10.1038/s41583-020-00418-4 · 2021 · External reference
Nav1.1‐overexpressing interneuron transplants restore brain rhythms and cognition in a mouse model of Alzheimer's disease
10.1016/j.neuron.2018.02.029 · 2018 · External reference
Focal and generalized seizure activity after local hippocampal or cortical ablation of NaV 1.1 channels in mice
10.1111/epi.16482 · 2020 · External reference
Focal Scn1a knockdown induces cognitive impairment without seizures
10.1016/j.nbd.2012.12.021 · 2013 · External reference
Cognitive deficits associated with Nav1.1 alterations: involvement of neuronal firing dynamics and oscillations
10.1371/journal.pone.0151538 · 2016 · External reference
Hippocampal deletion of NaV1.1 channels in mice causes thermal seizures and cognitive deficit characteristic of Dravet syndrome
10.1073/pnas.1906833116 · 2019 · External reference
Temporal manipulation of the Scn1a gene reveals its essential role in adult brain function
10.1093/brain/awad350 · 2024 · External reference
Mechanisms contributing to prefrontal cortex maturation during adolescence
10.1016/j.neubiorev.2016.05.013 · 2016 · External reference
GABAergic function as a limiting factor for prefrontal maturation during adolescence
10.1016/j.tins.2016.04.010 · 2016 · External reference
Scn1a haploinsufficiency in the prefrontal cortex leads to cognitive impairment and depressive phenotype
10.1093/brain/awae167 · 2024 · External reference
The impact of studying brain plasticity
10.3389/fncel.2019.00066 · 2019 · External reference
The yin and Yang of GABAergic and glutamatergic synaptic plasticity: opposites in balance by Crosstalking mechanisms
10.3389/fnsyn.2022.911020 · 2022 · External reference
Early developmental alterations of CA1 pyramidal cells in Dravet syndrome
10.1016/j.nbd.2024.106688 · 2024 · External reference
Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders
10.1186/s13073-019-0678-y · 2019 · External reference
10.1002/epi.70185
10.1002/epi.70185 · External reference
Kainate receptor‐mediated depression of glutamatergic transmission involving protein kinase a in the lateral amygdala
10.1111/j.1471-4159.2012.07665.x · 2012 · External reference
Prefrontal‐hippocampal interactions in episodic memory
10.1038/nrn.2017.74 · 2017 · External reference
Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model
10.1038/s41380-019-0615-x · 2020 · External reference
The medial prefrontal cortex in the rat: evidence for a dorso‐ventral distinction based upon functional and anatomical characteristics
10.1016/j.neubiorev.2003.09.003 · 2003 · External reference
Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses
10.1016/j.neuron.2012.08.038 · 2012 · External reference
Sleep impairment and reduced interneuron excitability in a mouse model of Dravet syndrome
10.1016/j.nbd.2015.02.016 · 2015 · External reference
EEG coherences of the fronto‐limbic circuit between patients with major depressive disorder and healthy controls
10.1016/j.jad.2023.03.055 · 2023 · External reference
Gamma oscillations correlate with working memory load in humans
10.1093/cercor/bhg084 · 2003 · External reference
Neural oscillations associated with item and temporal order maintenance in working memory
10.1523/jneurosci.0828-11.2011 · 2011 · External reference
Gamma and Beta bursts underlie working memory
10.1016/j.neuron.2016.02.028 · 2016 · External reference
Working memory 2.0
10.1016/j.neuron.2018.09.023 · 2018 · External reference
Prefrontal cortical‐specific differences in behavior and synaptic plasticity between adolescent and adult mice
10.1152/jn.00189.2017 · 2018 · External reference
Differences in stress‐induced changes in extinction and prefrontal plasticity in postweanling and adult animals
10.1016/j.biopsych.2014.10.004 · 2015 · External reference
Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum
10.1152/physrev.00063.2021 · 2023 · External reference
Interplay of epilepsy and long‐term potentiation: implications for memory
10.3389/fnins.2024.1451740 · 2024 · External reference
Chronic partial TrkB activation reduces seizures and mortality in a mouse model of Dravet syndrome
10.1073/pnas.2022726119 · 2022 · External reference
Scn1a‐GFP transgenic mouse revealed Nav1.1 expression in neocortical pyramidal tract projection neurons
10.7554/elife.87495 · 2023 · External reference
Impaired excitability of somatostatin‐ and parvalbumin‐expressing cortical interneurons in a mouse model of Dravet syndrome
2014 · External reference
Antisense oligonucleotides restore excitability, GABA signalling and sodium current density in a Dravet syndrome model
10.1093/brain/awad349 · 2024 · External reference
Developmental alterations in firing properties of hippocampal CA1 inhibitory and excitatory neurons in a mouse model of Dravet syndrome
10.1016/j.nbd.2020.105209 · 2021 · External reference
