Research graph
References from Cyproconazole‐Induced Systemic Neuro‐Immunotoxicity: An Integrated In Vivo and In Silico Study of Oxidative Stress, NLRP3‐Related Inflammatory Signaling, and Cholinergic Disruption. Local targets link to admitted publications; unresolved targets remain external evidence.
Neuroprotective Effect of Withania somnifera Leaves Extract Nanoemulsion Against Penconazole‐Induced Neurotoxicity in Albino Rats via Modulating TGF‐β1/Smad2 Signaling Pathway
10.1007/s10787-024-01461-8 · 2024 · External reference
Thiobencarb Induces Phenotypic Abnormalities, Apoptosis, and Cardiovascular Toxicity in Zebrafish Embryos Through Oxidative Stress and Inflammation
10.1016/j.cbpc.2022.109440 · 2022 · External reference
Evaluation of Hepatotoxicity and Nephrotoxicity Induced by Fenpyroximate in Subchronic‐Orally Exposed Wistar Rats
10.1080/1354750x.2022.2096928 · 2022 · External reference
Subchronic Exposure to Fenpyroximate Causes Multiorgan Toxicity in Wistar Rats by Disrupting Lipid Profile, Inducing Oxidative Stress and DNA Damage
10.1080/1354750x.2024.2313663 · 2024 · External reference
Cutting Edge: NF‐Kappa Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NRLP3 Expression
10.4049/jimmunol.0901363 · 2009 · External reference
A Rapid and Sensitive Method for the Quantification of Microgram Quantities of Protein Utilizing the Principle of Protein‐Dye Binding
10.1016/0003-2697(76)90527-3 · 1976 · External reference
10.1373/clinchem.2008.112797
10.1373/clinchem.2008.112797 · External reference
Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin‐Induced Cell and Mouse Models of Parkinson's Disease
10.3390/ijms24032642 · 2023 · External reference
Unresolved reference
1985 · External reference
Oxidative Damage to DNA: Do We Have a Reliable Biomarker? Environ
10.1289/ehp.96104s3465 · 1996 · External reference
Automatic Neural Regulation of Immunity
10.1111/j.1365-2796.2004.01442.x · 2005 · External reference
Acetylcholinesterase and Butyrylcholiesterase as Possible as Markers of Low‐Grade Systemic Inflammation
2007 · External reference
Conclusion on the Peer Review of the Pesticide Risk Assessment of the Active Substance Cyproconazole
2010 · External reference
A New and Rapid Coloremtric Determination of Acethylcholinesterase Activity
10.1016/0006-2952(61)90145-9 · 1961 · External reference
Mechanisms Regarding Respiratory Toxicity Triggered by Accumulation of ROS in Carp Exposed to Difenoconazole
10.1016/j.pestbp.2023.105343 · 2023 · External reference
Unresolved reference
2009 · External reference
Assays of Glutathione Peroxidase
10.1016/s0076-6879(84)05015-1 · 1984 · External reference
Effect of Turfgrass on Soil Mobility and Dissipation of Cyproconazole
10.2135/cropsci2000.4051333x · 2000 · External reference
Unresolved reference
2020 · External reference
Glutathione S‐Transferases, the First Enzymatic Step in Mercapturic Acid Formation
1974 · External reference
10.1016/j.chemosphere
10.1016/j.chemosphere · External reference
Stereostructure‐Activity Mechanism of Cyproconazole by Cytochrome P450 in Rat Liver Microsomes: A Combined Experimental and Computational Study
10.1016/j.jhazmat.2021.125764 · 2021 · External reference
Targeted and Untargeted Analysis of Triazole Fungicides and Their Metabolites in Fruits and Vegetables by UHPLC‐Orbitrap‐MS (2)
10.1016/j.foodchem.2021.130860 · 2022 · External reference
NLRP3 Inflammasome Activation and Cell Death
10.1038/s41423-021-00740-6 · 2021 · External reference
Unresolved reference
2012 · External reference
Unresolved reference
2011 · External reference
The Lymphotic Cholinergic System and Its Contribution to the Regulation of Immune Activity
10.1016/j.lfs.2003.09.037 · 2003 · External reference
Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System
10.3390/ijms23042030 · 2022 · External reference
Difenoconazole Disrupts the Blood‐Brain Barrier and Results in Neurotoxicity in Carp by Inhibiting the Nrf2 Pathway Mediated ROS Accumulation
10.1016/j.ecoenv.2022.114081 · 2022 · External reference
Analysis of Relative Gene Expression Data Using Real Time Quantitative PCR and the 2‐DDCT Methods
10.1006/meth.2001.1262 · 2001 · External reference
α7nAChR on B Cells Directs T Cell Differentiation to Prevent Viral Myocarditis
10.1172/jci.insight.189323 · 2025 · External reference
Adverse Outcome Pathway‐Driven Analysis of Liver Steatosis in Vitro: A Case Study With Cyproconazole
10.1021/acs.chemrestox.8b00112 · 2018 · External reference
Effect of Propiconazole on Neutrophil Extracellular Traps Formation: Assessing the Role of Autophagyy
2022 · External reference
Development Toxicity of Cyproconazole, an Inhibitor of Fungal Ergosterol Biosynthesis in the Rat
10.1007/bf00195106 · 1995 · External reference
Aggravation of TGFβ1‐Smad Pathway and Autoimmune Myocarditis by Fungicide (Tebuconazole) Exposure
10.3390/ijms241411510 · 2023 · External reference
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
10.1111/j.1432-1033.1974.tb03714.x · 1974 · External reference
Hepatotoxic Effects of Cyproconazole and Prochloraz in Wild‐Type and hCAR/hPXR Mice
10.1007/s00204-016-1925-2 · 2017 · External reference
The NLRP3 Inflammasome in Ischemic Stroke
2024 · External reference
Lipid and Protein Oxidation In Vitro, and Antioxidant Potential in Meat From Charolais Cows Finished on Pasture or Mixed Diet
10.1016/s0309-1740(03)00135-9 · 2004 · External reference
Rationale for LDH‐Targeted Cancer Immunotherapy
10.1016/j.ejca.2022.11.032 · 2023 · External reference
The Ameliorative Effect of N‐Acetylcysteine Against Penconazole Induced Neurodegenerative and Neuroinflammatory Disorders in Rats
10.1002/jbt.22884 · 2021 · External reference
AutoDck4 and AutoDockTools4: Automated Docking With Selective Receptor Flexibilty
10.1002/jcc.21256 · 2009 · External reference
Neuroimmune Communication in the Kidney
10.31662/jmaj.2020-0024 · 2020 · External reference
Unresolved reference
2008 · External reference
Assay for Lipid Peroxide in Animal Tissues by Thiobarbituric Acid Reaction
10.1016/0003-2697(79)90738-3 · 1979 · External reference
Reporting Animal Research: Explantation and Elaboration for the ARRIVE Guidelines 2.0
10.1371/journal.pbio.3000411 · 2020 · External reference
Cholinergic Anti‐Inflammatory Pathway and Vagus Nerve Stimulation in Rheumatoid Arthritis
10.1097/bor.0000000000001170 · 2026 · External reference
Bromuconazole Caused Genotoxicity and Hepatic and Renal Damage via Oxidative Stress Process in Wistar Rats
10.1007/s11356-021-16091-8 · 2022 · External reference
Potential Involvement of Oxidative Stress, Apoptosis and Proinflammation in Ipconazole‐Induced Cytotoxicity in Human Endothelial‐Like Cells
10.3390/toxics11100839 · 2023 · External reference
Effects of Zinc Supplementation on Oxidant/Antioxidant and Lipids Status of Pesticides Sprayers
10.1515/jcim-2019-0001 · 2019 · External reference
Inflammasomes and Signaling Pathways: Key Mechanisms in the Pathophysiology of Sepsis
10.3390/cells14120930 · 2025 · External reference
Neuroprotective Role of Carvacrol via Nrf2/HO‐1/NLRP3 Axis in Rotenone‐Induced PD Mice Model
10.1016/j.brainres.2024.148954 · 2024 · External reference
A Simple Technique for Quantitation of Low Levels of DNA Damage in Individual Cells
10.1016/0014-4827(88)90265-0 · 1988 · External reference
Effects of the Fungicide Prothioconazole on Lipid Metabolism in Mice: Whitening Alterations of Brown Adipose Tissue
10.1021/acs.est.4c05666 · 2024 · External reference
Mitochondrial and Transcriptome Responses in Rat Dopaminergic Neuronal Cells Following Exposure to the Insecticide Fipronil
10.1016/j.neuro.2021.05.011 · 2021 · External reference
10.1016/j.pestbp.2023.105646
10.1016/j.pestbp.2023.105646 · External reference
Endocrine‐Disrupting Activities in Vivo of the Fungicides Tebuconazole and Epoxiconazole
10.1093/toxsci/kfm227 · 2007 · External reference
Pentachlorophenol Mediated Regulation of DAMPs and Inflammation: In Vitro Study
10.1016/j.tiv.2022.105378 · 2022 · External reference
The Single Cell Gel/ Comet Assay: Guidelines for in Vitro and in Vivo Genetic Toxicology Testing
10.1002/(sici)1098-2280(2000)35:3<206::aid-em8>3.0.co;2-j · 2000 · External reference
Trends in Agricltural Triazole Fungicide Use in the United States, 1992‐2016 and Possible Implication for Antifungal Resistant Fungi in Human Disease
10.1289/ehp7484 · 2021 · External reference
NLRP3 Inflammasome Activation: The Convergence of Multiple Signalling Pathways on ROS Production
10.1038/nri2725 · 2010 · External reference
A Case Study With Triazole Fungicides to Explore Practical Application of Next‐Generation Hazard Assessment Methods for Human Health
10.1021/acs.chemrestox.9b00484 · 2020 · External reference
Difenoconazole Causes Cardiotoxicity in Common Carp (Cyprinus carpio): Involvement of Oxidative Stress, Inflammation, Apoptosis and Autophagy
10.1016/j.chemosphere.2022.135562 · 2022 · External reference
Amphibian (Rana nigromaculata) Exposed to Cyproconazole: Changes in Growth Index, Behavioral Endpoints, Antioxidant Biomarkers, Thyroid and Gonad Development
10.1016/j.aquatox.2018.12.015 · 2019 · External reference
Enantioselective Toxic Effects of Cyproconazole Enantiomers Against Rana nigromaculata
10.1016/j.envpol.2018.09.060 · 2018 · External reference
Thioredoxin‐Interacting Protein Links Oxidative Stress to Inflammasome Activation
10.1038/ni.1831 · 2010 · External reference
The Single Cell Gel/ Comet Assay: Guidelines for in Vitro and in Vivo Genetic Toxicology Testing
10.1002/(sici)1098-2280(2000)35:3<206::aid-em8>3.0.co;2-j · ExternalCitation · doi-reference
The Ameliorative Effect of N‐Acetylcysteine Against Penconazole Induced Neurodegenerative and Neuroinflammatory Disorders in Rats
10.1002/jbt.22884 · ExternalCitation · doi-reference
AutoDck4 and AutoDockTools4: Automated Docking With Selective Receptor Flexibilty
10.1002/jcc.21256 · ExternalCitation · doi-reference
Analysis of Relative Gene Expression Data Using Real Time Quantitative PCR and the 2‐DDCT Methods
10.1006/meth.2001.1262 · ExternalCitation · doi-reference
Development Toxicity of Cyproconazole, an Inhibitor of Fungal Ergosterol Biosynthesis in the Rat
10.1007/bf00195106 · ExternalCitation · doi-reference
Hepatotoxic Effects of Cyproconazole and Prochloraz in Wild‐Type and hCAR/hPXR Mice
10.1007/s00204-016-1925-2 · ExternalCitation · doi-reference
Neuroprotective Effect of Withania somnifera Leaves Extract Nanoemulsion Against Penconazole‐Induced Neurotoxicity in Albino Rats via Modulating TGF‐β1/Smad2 Signaling Pathway
10.1007/s10787-024-01461-8 · ExternalCitation · doi-reference
Bromuconazole Caused Genotoxicity and Hepatic and Renal Damage via Oxidative Stress Process in Wistar Rats
10.1007/s11356-021-16091-8 · ExternalCitation · doi-reference
A Rapid and Sensitive Method for the Quantification of Microgram Quantities of Protein Utilizing the Principle of Protein‐Dye Binding
10.1016/0003-2697(76)90527-3 · ExternalCitation · doi-reference
Assay for Lipid Peroxide in Animal Tissues by Thiobarbituric Acid Reaction
10.1016/0003-2697(79)90738-3 · ExternalCitation · doi-reference
A New and Rapid Coloremtric Determination of Acethylcholinesterase Activity
10.1016/0006-2952(61)90145-9 · ExternalCitation · doi-reference
A Simple Technique for Quantitation of Low Levels of DNA Damage in Individual Cells
10.1016/0014-4827(88)90265-0 · ExternalCitation · doi-reference
Amphibian (Rana nigromaculata) Exposed to Cyproconazole: Changes in Growth Index, Behavioral Endpoints, Antioxidant Biomarkers, Thyroid and Gonad Development
10.1016/j.aquatox.2018.12.015 · ExternalCitation · doi-reference
Neuroprotective Role of Carvacrol via Nrf2/HO‐1/NLRP3 Axis in Rotenone‐Induced PD Mice Model
10.1016/j.brainres.2024.148954 · ExternalCitation · doi-reference
Thiobencarb Induces Phenotypic Abnormalities, Apoptosis, and Cardiovascular Toxicity in Zebrafish Embryos Through Oxidative Stress and Inflammation
10.1016/j.cbpc.2022.109440 · ExternalCitation · doi-reference
10.1016/j.chemosphere
10.1016/j.chemosphere · ExternalCitation · doi-reference
Difenoconazole Causes Cardiotoxicity in Common Carp (Cyprinus carpio): Involvement of Oxidative Stress, Inflammation, Apoptosis and Autophagy
10.1016/j.chemosphere.2022.135562 · ExternalCitation · doi-reference
Difenoconazole Disrupts the Blood‐Brain Barrier and Results in Neurotoxicity in Carp by Inhibiting the Nrf2 Pathway Mediated ROS Accumulation
10.1016/j.ecoenv.2022.114081 · ExternalCitation · doi-reference
Rationale for LDH‐Targeted Cancer Immunotherapy
10.1016/j.ejca.2022.11.032 · ExternalCitation · doi-reference
Enantioselective Toxic Effects of Cyproconazole Enantiomers Against Rana nigromaculata
10.1016/j.envpol.2018.09.060 · ExternalCitation · doi-reference
Targeted and Untargeted Analysis of Triazole Fungicides and Their Metabolites in Fruits and Vegetables by UHPLC‐Orbitrap‐MS (2)
10.1016/j.foodchem.2021.130860 · ExternalCitation · doi-reference
Stereostructure‐Activity Mechanism of Cyproconazole by Cytochrome P450 in Rat Liver Microsomes: A Combined Experimental and Computational Study
10.1016/j.jhazmat.2021.125764 · ExternalCitation · doi-reference
The Lymphotic Cholinergic System and Its Contribution to the Regulation of Immune Activity
10.1016/j.lfs.2003.09.037 · ExternalCitation · doi-reference
Mitochondrial and Transcriptome Responses in Rat Dopaminergic Neuronal Cells Following Exposure to the Insecticide Fipronil
10.1016/j.neuro.2021.05.011 · ExternalCitation · doi-reference
Mechanisms Regarding Respiratory Toxicity Triggered by Accumulation of ROS in Carp Exposed to Difenoconazole
10.1016/j.pestbp.2023.105343 · ExternalCitation · doi-reference
10.1016/j.pestbp.2023.105646
10.1016/j.pestbp.2023.105646 · ExternalCitation · doi-reference
Pentachlorophenol Mediated Regulation of DAMPs and Inflammation: In Vitro Study
10.1016/j.tiv.2022.105378 · ExternalCitation · doi-reference
Assays of Glutathione Peroxidase
10.1016/s0076-6879(84)05015-1 · ExternalCitation · doi-reference
Lipid and Protein Oxidation In Vitro, and Antioxidant Potential in Meat From Charolais Cows Finished on Pasture or Mixed Diet
10.1016/s0309-1740(03)00135-9 · ExternalCitation · doi-reference
Adverse Outcome Pathway‐Driven Analysis of Liver Steatosis in Vitro: A Case Study With Cyproconazole
10.1021/acs.chemrestox.8b00112 · ExternalCitation · doi-reference
A Case Study With Triazole Fungicides to Explore Practical Application of Next‐Generation Hazard Assessment Methods for Human Health
10.1021/acs.chemrestox.9b00484 · ExternalCitation · doi-reference
Effects of the Fungicide Prothioconazole on Lipid Metabolism in Mice: Whitening Alterations of Brown Adipose Tissue
10.1021/acs.est.4c05666 · ExternalCitation · doi-reference
Thioredoxin‐Interacting Protein Links Oxidative Stress to Inflammasome Activation
10.1038/ni.1831 · ExternalCitation · doi-reference
NLRP3 Inflammasome Activation: The Convergence of Multiple Signalling Pathways on ROS Production
10.1038/nri2725 · ExternalCitation · doi-reference
NLRP3 Inflammasome Activation and Cell Death
10.1038/s41423-021-00740-6 · ExternalCitation · doi-reference
Evaluation of Hepatotoxicity and Nephrotoxicity Induced by Fenpyroximate in Subchronic‐Orally Exposed Wistar Rats
10.1080/1354750x.2022.2096928 · ExternalCitation · doi-reference
Subchronic Exposure to Fenpyroximate Causes Multiorgan Toxicity in Wistar Rats by Disrupting Lipid Profile, Inducing Oxidative Stress and DNA Damage
10.1080/1354750x.2024.2313663 · ExternalCitation · doi-reference
Endocrine‐Disrupting Activities in Vivo of the Fungicides Tebuconazole and Epoxiconazole
10.1093/toxsci/kfm227 · ExternalCitation · doi-reference
Cholinergic Anti‐Inflammatory Pathway and Vagus Nerve Stimulation in Rheumatoid Arthritis
10.1097/bor.0000000000001170 · ExternalCitation · doi-reference
Automatic Neural Regulation of Immunity
10.1111/j.1365-2796.2004.01442.x · ExternalCitation · doi-reference
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
10.1111/j.1432-1033.1974.tb03714.x · ExternalCitation · doi-reference
α7nAChR on B Cells Directs T Cell Differentiation to Prevent Viral Myocarditis
10.1172/jci.insight.189323 · ExternalCitation · doi-reference
Oxidative Damage to DNA: Do We Have a Reliable Biomarker? Environ
10.1289/ehp.96104s3465 · ExternalCitation · doi-reference
Trends in Agricltural Triazole Fungicide Use in the United States, 1992‐2016 and Possible Implication for Antifungal Resistant Fungi in Human Disease
10.1289/ehp7484 · ExternalCitation · doi-reference
Reporting Animal Research: Explantation and Elaboration for the ARRIVE Guidelines 2.0
10.1371/journal.pbio.3000411 · ExternalCitation · doi-reference
10.1373/clinchem.2008.112797
10.1373/clinchem.2008.112797 · ExternalCitation · doi-reference
Effects of Zinc Supplementation on Oxidant/Antioxidant and Lipids Status of Pesticides Sprayers
10.1515/jcim-2019-0001 · ExternalCitation · doi-reference
Effect of Turfgrass on Soil Mobility and Dissipation of Cyproconazole
10.2135/cropsci2000.4051333x · ExternalCitation · doi-reference
Neuroimmune Communication in the Kidney
10.31662/jmaj.2020-0024 · ExternalCitation · doi-reference
Inflammasomes and Signaling Pathways: Key Mechanisms in the Pathophysiology of Sepsis
10.3390/cells14120930 · ExternalCitation · doi-reference
Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System
10.3390/ijms23042030 · ExternalCitation · doi-reference
Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin‐Induced Cell and Mouse Models of Parkinson's Disease
10.3390/ijms24032642 · ExternalCitation · doi-reference
Aggravation of TGFβ1‐Smad Pathway and Autoimmune Myocarditis by Fungicide (Tebuconazole) Exposure
10.3390/ijms241411510 · ExternalCitation · doi-reference
Potential Involvement of Oxidative Stress, Apoptosis and Proinflammation in Ipconazole‐Induced Cytotoxicity in Human Endothelial‐Like Cells
10.3390/toxics11100839 · ExternalCitation · doi-reference
Cutting Edge: NF‐Kappa Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NRLP3 Expression
10.4049/jimmunol.0901363 · ExternalCitation · doi-reference
