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References from Development of Paquinimod‐Loaded Implants to Modulate the Foreign Body Response. Local targets link to admitted publications; unresolved targets remain external evidence.
Don't Judge an Implant by Its Cover: How the Foreign Body Response and Fibrotic Capsule Might Be Harnessed for Good
10.1038/s44385-025-00053-7 · 2026 · External reference
Foreign Body Reaction to Biomaterials
10.1016/j.smim.2007.11.004 · 2008 · External reference
Unresolved reference
2011 · External reference
Engineering Physical Microenvironments to Study Innate Immune Cell Biophysics
10.1063/5.0098578 · 2022 · External reference
Unresolved reference
External reference
Implantable Medical Devices, Biomaterials, and the Foreign Body Response: A Surgical Perspective
10.1002/jbm.a.37983 · 2025 · External reference
Macrophages, Foreign Body Giant Cells and Their Response to Implantable Biomaterials
10.3390/ma8095269 · 2015 · External reference
Capsular Contractures: A Systematic Review
10.1097/prs.0b013e3181bf7f26 · 2009 · External reference
In Vitro and In Vivo Models for Assessing the Host Response to Biomaterials
2017 · External reference
Glucose Sensor Membranes for Mitigating the Foreign Body Response
10.1177/193229681100500505 · 2011 · External reference
Successful Treatment of Cutaneous Foreign Body Granuloma With JAK Inhibitor Abrocitinib and Prednisone: A Case Report
10.2147/ccid.s522469 · 2025 · External reference
Nanopatterned Bulk Metallic Glass‐Based Biomaterials Modulate Macrophage Polarization
10.1016/j.actbio.2018.05.051 · 2018 · External reference
Dexamethasone/PLGA Microspheres for Continuous Delivery of an Anti‐Inflammatory Drug for Implantable Medical Devices
10.1016/s0142-9612(01)00291-5 · 2002 · External reference
Shifts in Macrophage Phenotype at the Biomaterial Interface via IL‐4 Eluting Coatings Are Associated With Improved Implant Integration
10.1016/j.biomaterials.2016.10.019 · 2017 · External reference
Multicompartment Drug Release System for Dynamic Modulation of Tissue Responses
10.1002/adhm.201700370 · 2017 · External reference
Vascular Endothelial Growth Factor and Dexamethasone Release From Nonfouling Sensor Coatings Affect the Foreign Body Response
10.1002/jbm.a.31088 · 2007 · External reference
Assessing the Effects of VEGF Releasing Microspheres on the Angiogenic and Foreign Body Response to a 3D Printed Silicone‐Based Macroencapsulation Device
10.3390/pharmaceutics13122077 · 2021 · External reference
Overcoming Roadblocks to Anti‐Inflammatory NLRP3 Inhibitors
10.1038/d41573-025-00156-1 · 2025 · External reference
Prevention of the Foreign Body Response to Implantable Medical Devices by Inflammasome Inhibition
10.1073/pnas.2115857119 · 2022 · External reference
A Review of the Foreign‐Body Response to Subcutaneously‐Implanted Devices: The Role of Macrophages and Cytokines in Biofouling and Fibrosis
10.1177/193229680800200504 · 2008 · External reference
Localized Immunomodulation With Cytokine‐Producing Cells to Mitigate Foreign Body Responses in Rodents and a Nonhuman Primate
10.1126/sciadv.aec7053 · 2026 · External reference
The Effect of the Foreign Body Response on Drug Elution From Subdermal Delivery Systems
10.1016/j.biomaterials.2025.123110 · 2025 · External reference
Implantable Drug Delivery Systems and Foreign Body Reaction: Traversing the Current Clinical Landscape
2021 · External reference
Domesticating the Foreign Body Response: Recent Advances and Applications
10.1016/j.addr.2019.08.010 · 2019 · External reference
Biomedical and Tissue Engineering Strategies to Control Foreign Body Reaction to Invasive Neural Electrodes
10.3389/fbioe.2021.659033 · 2021 · External reference
TLR4 Signaling Pathway Modulators as Potential Therapeutics in Inflammation and Sepsis
10.3390/vaccines5040034 · 2017 · External reference
Immunocompatible Elastomer With Increased Resistance to the Foreign Body Response
10.1038/s41467-024-52023-z · 2024 · External reference
Amelioration of Experimental Autoimmune Encephalomyelitis by the Quinoline‐3‐Carboxamide Paquinimod: Reduced Priming of Proinflammatory Effector CD4+ T Cells
10.1016/j.ajpath.2013.01.032 · 2013 · External reference
The Immunomodulatory Quinoline‐3‐Carboxamide Paquinimod Reverses Established Fibrosis in a Novel Mouse Model for Liver Fibrosis
10.1371/journal.pone.0203228 · 2018 · External reference
Paquinimod Reduces Skin Fibrosis in Tight Skin 1 Mice, an Experimental Model of Systemic Sclerosis
10.1016/j.jdermsci.2016.04.006 · 2016 · External reference
Pharmacokinetics, Tolerability, and Preliminary Efficacy of Paquinimod (ABR‐215757), a New Quinoline‐3‐Carboxamide Derivative: Studies in Lupus‐Prone Mice and a Multicenter, Randomized, Double‐Blind, Placebo‐Controlled, Repeat‐Dose, Dose‐Ranging Study in Patients With Systemic Lupus Erythematosus
10.1002/art.33493 · 2012 · External reference
Local Delivery Strategies to Restore Immune Homeostasis in the Context of Inflammation
10.1016/j.addr.2021.113971 · 2021 · External reference
Unresolved reference
External reference
Decellularized Materials Derived From TSP2‐KO Mice Promote Enhanced Neovascularization and Integration in Diabetic Wounds
10.1016/j.biomaterials.2018.03.049 · 2018 · External reference
Histochemical and Biochemical Analysis of Collagen Content in Formalin‐Fixed, Paraffin Embedded Colonic Samples
10.1016/j.mex.2023.102416 · 2023 · External reference
A Guide to Modern Statistical Analysis of Immunological Data
10.1186/1471-2172-8-27 · 2007 · External reference
Samples in Many Cell‐Based Experiments Are Matched/Paired but Taking This Into Account Does Not Always Increase Power of Statistical Tests for Differences in Means
2023 · External reference
Evaluation of Phenotypic and Functional Stability of RAW 264.7 Cell Line Through Serial Passages
10.1371/journal.pone.0198943 · 2018 · External reference
F4/80 as a Major Macrophage Marker: The Case of the Peritoneum and Spleen
10.1007/978-3-319-54090-0_7 · 2017 · External reference
Unresolved reference
External reference
Device‐Based Local Delivery of siRNA Against Mammalian Target of Rapamycin (mTOR) in a Murine Subcutaneous Implant Model to Inhibit Fibrous Encapsulation
10.1016/j.jconrel.2010.08.019 · 2010 · External reference
Concurrent Delivery of Dexamethasone and VEGF for Localized Inflammation Control and Angiogenesis
10.1016/j.jconrel.2006.10.013 · 2007 · External reference
Long‐Term Implant Fibrosis Prevention in Rodents and Non‐Human Primates Using Crystallized Drug Formulations
10.1038/s41563-019-0377-5 · 2019 · External reference
ROS: Basic Concepts, Sources, Cellular Signaling, and Its Implications in Aging Pathways
10.1155/2022/1225578 · 2022 · External reference
Real‐Time In Vivo Detection of Biomaterial‐Induced Reactive Oxygen Species
10.1016/j.biomaterials.2010.11.029 · 2011 · External reference
S100A9 Induces Reactive Oxygen Species‐Dependent Formation of Neutrophil Extracellular Traps in Abdominal Sepsis
10.1016/j.yexcr.2022.113405 · 2022 · External reference
Stimulation and Priming of Human Neutrophils by IL‐1 Alpha and IL‐1 Beta: Complete Inhibition by IL‐1 Receptor Antagonist and no Interaction With Other Cytokines
1995 · External reference
Novel Role of IL (Interleukin)‐1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic Aneurysms
10.1161/atvbaha.117.309897 · 2018 · External reference
Multiple Roles for Chemokines in Neutrophil Biology
10.3389/fimmu.2020.01259 · 2020 · External reference
The CC Chemokine Ligand, CCL2/MCP1, Participates in Macrophage Fusion and Foreign Body Giant Cell Formation
10.1016/s0002-9440(10)63265-8 · 2004 · External reference
IL‐6: A Regulator of the Transition From Neutrophil to Monocyte Recruitment During Inflammation
10.1016/s1471-4906(02)00013-3 · 2003 · External reference
The Role of CXCL2‐Mediated Crosstalk Between Tumor Cells and Macrophages in Fusobacterium nucleatum ‐Promoted Oral Squamous Cell Carcinoma Progression
10.1038/s41419-024-06640-7 · 2024 · External reference
CXCL2: A Key Player in the Tumor Microenvironment and Inflammatory Diseases
10.1186/s12935-025-03765-3 · 2025 · External reference
Interleukin‐1 Beta‐A Friend or Foe in Malignancies?
10.3390/ijms19082155 · 2018 · External reference
Interleukin‐1β Triggers the Differentiation of Macrophages With Enhanced Capacity to Present Mycobacterial Antigen to T Cells
10.1111/imm.12167 · 2014 · External reference
IL‐6 in Inflammation, Immunity, and Disease
10.1101/cshperspect.a016295 · 2014 · External reference
Interleukin‐6 Signaling Drives Fibrosis in Unresolved Inflammation
10.1016/j.immuni.2013.10.022 · 2014 · External reference
Tumor Necrosis Factor‐α Signaling in Macrophages
10.1615/critreveukargeneexpr.v20.i2.10 · 2010 · External reference
The Nuclear Factor Kappa B (NF‐kB) Signaling in Cancer Development and Immune Diseases
10.1016/j.gendis.2020.06.005 · 2021 · External reference
MyD88: A Central Player in Innate Immune Signaling
10.12703/p6-97 · 2014 · External reference
Transcriptional Signaling by Double‐Stranded RNA: Role of TLR3
10.1016/j.cytogfr.2005.01.006 · 2005 · External reference
Influence of Diabetes on the Foreign Body Response to Nitric Oxide‐Releasing Implants
10.1016/j.biomaterials.2017.11.044 · 2018 · External reference
Effects of Age‐Related Shifts in Cellular Function and Local Microenvironment Upon the Innate Immune Response to Implants
10.1016/j.smim.2017.05.001 · 2017 · External reference
Upregulation of Foreign Body Response in Obese Mice
10.1002/oby.22102 · 2018 · External reference
Engineered Immunological Niches to Monitor Disease Activity and Treatment Efficacy in Relapsing Multiple Sclerosis
10.1038/s41467-020-17629-z · 2020 · External reference
Engineered Immunological Niche Directs Therapeutic Development in Models of Progressive Multiple Sclerosis
10.1073/pnas.2409852122 · 2025 · External reference
Poly(Caprolactone)‐Based Coatings on 3D‐Printed Biodegradable Implants: A Novel Strategy to Prolong Delivery of Hydrophilic Drugs
10.1021/acs.molpharmaceut.0c00515 · 2020 · External reference
Improvement of Osteogenesis by a Uniform PCL Coating on a Magnesium Screw for Biodegradable Applications
10.1038/s41598-018-31359-9 · 2018 · External reference
