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References from Estradiol Promotes Tumor Progression in ERα‐Low Endometrial Cancer via the GPER/SphK1 Pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Endometrial Carcinoma: Pathology and Genetics
10.1080/00313020601136153 · 2007 · External reference
Type I and II Endometrial Cancers: Have They Different Risk Factors?
10.1200/jco.2012.48.2596 · 2013 · External reference
The Levels of the Sex Hormones Are Not Different Between Type 1 and Type 2 Endometrial Cancer
10.1038/srep39744 · 2016 · External reference
Is the Positivity of Estrogen Receptor or Progesterone Receptor Different Between Type 1 and Type 2 Endometrial Cancer?
10.18632/oncotarget.13471 · 2017 · External reference
Tumor Estrogen Content and Clinico‐Morphological and Endocrine Features of Endometrial Cancer
10.1007/s00432-003-0427-9 · 2003 · External reference
GPR30: A G Protein‐Coupled Receptor for Estrogen
10.1016/j.mce.2006.12.010 · 2007 · External reference
Estrogenic G Protein‐Coupled Receptor 30 Signaling Is Involved in Regulation of Endometrial Carcinoma by Promoting Proliferation, Invasion Potential, and interleukin‐6 Secretion via the MEK/ERK Mitogen‐Activated Protein Kinase Pathway
10.1111/j.1349-7006.2009.01148.x · 2009 · External reference
Effects of 4‐Hydroxytamoxifen, Raloxifene and ICI 182 780 on Survival of Uterine Cancer Cell Lines in the Presence and Absence of Exogenous Estrogens
10.3892/ijo.30.2.477 · 2007 · External reference
RETRACTED: 17β‐Estradiol, Genistein, and 4‐Hydroxytamoxifen Induce the Proliferation of Thyroid Cancer Cells Through the G Protein‐Coupled Receptor GPR30
10.1124/mol.106.026344 · 2006 · External reference
The Positivity of G‐Protein‐Coupled Receptor‐30 (GPR30), an Alternative Estrogen Receptor Is Not Different Between Type 1 and Type 2 Endometrial Cancer
10.18632/oncotarget.18545 · 2017 · External reference
GPR30 and Estrogen Receptor Expression: New Insights Into Hormone Dependence of Inflammatory Breast Cancer
10.1007/s10549-009-0631-7 · 2010 · External reference
Contributions of Estrogen to ER‐Negative Breast Tumor Growth
10.1016/j.jsbmb.2006.09.025 · 2006 · External reference
GPR30: A Novel Indicator of Poor Survival for Endometrial Carcinoma
10.1016/j.ajog.2007.01.004 · 2007 · External reference
High GPER Expression in Triple‐Negative Breast Cancer Is Linked to Pro‐Metastatic Pathways and Predicts Poor Patient Outcomes
10.1038/s41523-022-00472-4 · 2022 · External reference
Estrogen Promotes the Proliferation and Migration of Endometrial Cancer Through the GPER‐Mediated NOTCH Pathway
10.1002/jbt.70129 · 2025 · External reference
Comprehensive Genomic and Immunohistochemical Profiling to Predict Prognosis and Recurrence in Fertility‐Sparing Therapy Based on Progesterone for Endometrial Carcinoma
10.1177/15330338251349972 · 2025 · External reference
Prognostic Refinement of NSMP High‐Risk Endometrial Cancers Using Oestrogen Receptor Immunohistochemistry
10.1038/s41416-023-02141-0 · 2023 · External reference
G Protein‐Coupled Estrogen Receptor‐Selective Ligands Modulate Endometrial Tumor Growth
10.1155/2013/472720 · 2013 · External reference
Estradiol and Tamoxifen Induce Cell Migration Through GPR30 and Activation of Focal Adhesion Kinase (FAK) in Endometrial Cancers With Low or Without Nuclear Estrogen Receptor α (ERα)
10.1371/journal.pone.0072999 · 2013 · External reference
The G Protein‐Coupled Receptor GPR30 Mediates the Nontranscriptional Effect of Estrogen on the Activation of PI3K/Akt Pathway in Endometrial Cancer Cells
10.1097/igc.0b013e31827912b8 · 2013 · External reference
GPER Mediates Enhanced Cell Viability and Motility via Non‐Genomic Signaling Induced by 17β‐estradiol in Triple‐Negative Breast Cancer Cells
10.1016/j.jsbmb.2014.05.003 · 2014 · External reference
SPHK1 Regulates Proliferation and Survival Responses in Triple‐Negative Breast Cancer
10.18632/oncotarget.1874 · 2014 · External reference
Metastatic Triple‐Negative Breast Cancer Is Dependent on SphKs/S1P Signaling for Growth and Survival
10.1016/j.cellsig.2017.01.021 · 2017 · External reference
Sphingosine Kinase Type 1 Promotes Estrogen‐Dependent Tumorigenesis of Breast Cancer MCF‐7 Cells
10.1006/excr.2002.5658 · 2002 · External reference
GPER Acts Through the cAMP/Epac/JNK/AP‐1 Pathway to Induce Transcription of Alpha 2C Adrenoceptor in Human Microvascular Smooth Muscle Cells
10.1097/fjc.0000000000001489 · 2023 · External reference
G Protein Estrogen Receptor as a Potential Therapeutic Target in Raynaud's Phenomenon
10.3389/fphar.2022.1061374 · 2022 · External reference
GPER Deletion Triggers Inhibitory Effects in Triple Negative Breast Cancer (TNBC) Cells Through the JNK/c‐Jun/p53/Noxa Transduction Pathway
10.1038/s41420-023-01654-0 · 2023 · External reference
Sphingosine Kinase 1 Promotes Growth of Glioblastoma by Increasing Inflammation Mediated by the NF‐κB/IL‐6/STAT3 and JNK/PTX3 Pathways
10.1016/j.apsb.2022.09.012 · 2022 · External reference
Targeting SphK1/2 by SKI‐178 Inhibits Prostate Cancer Cell Growth
10.1038/s41419-023-06023-4 · 2023 · External reference
Targeting Sphingosine Kinase 1/2 by a Novel Dual Inhibitor SKI‐349 Suppresses Non‐Small Cell Lung Cancer Cell Growth
10.1038/s41419-022-05049-4 · 2022 · External reference
Comprehensive Understanding of the Role of GPER in Estrogen Receptor‐Alpha Negative Breast Cancer
10.1016/j.jsbmb.2024.106523 · 2024 · External reference
Discovery and Evaluation of Inhibitors of Human Sphingosine Kinase
2003 · External reference
Sphingosine Kinase 1 Signaling in Breast Cancer: A Potential Target to Tackle Breast Cancer Stem Cells
10.3389/fmolb.2021.748470 · 2021 · External reference
Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple‐Negative Breast Cancer
10.1158/0008-5472.can-18-3803 · 2019 · External reference
