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References from Helicobacter pylori Outer Membrane Vesicles Engage TLR2 Through NapA to Promote Epithelial Association and Inflammatory Signalling. Local targets link to admitted publications; unresolved targets remain external evidence.
Activation of Human Neutrophils With Helicobacter pylori and the Role of Toll‐Like Receptors 2 and 4 in the Response
10.1111/j.1574-695x.2007.00327.x · 2007 · External reference
The Neutrophil‐Activating Protein of Helicobacter pylori Promotes Th1 Immune Responses
10.1172/jci27177 · 2006 · External reference
Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1‐Mediated Innate Immune Responses
10.1158/0008-5472.can-15-2272 · 2016 · External reference
Coadaptation of Helicobacter pylori and Humans: Ancient History, Modern Implications
10.1172/jci38605 · 2009 · External reference
Deficiency of the Myeloid Differentiation Primary Response Molecule MyD88 Leads to an Early and Rapid Development of Helicobacter‐Induced Gastric Malignancy
10.1128/iai.01344-13 · 2014 · External reference
Helicobacter pylori in Human Health and Disease: Mechanisms for Local Gastric and Systemic Effects
10.3748/wjg.v24.i28.3071 · 2018 · External reference
Pattern‐Recognition Receptors and Gastric Cancer
2014 · External reference
Helicobacter pylori‐Derived Outer Membrane Vesicles: Pathogenic Roles, Microbiota Interactions, and Biomedical Applications
10.1016/j.jare.2025.09.055 · 2026 · External reference
Helicobacter pylori Outer Membrane Vesicles Involvement in the Infection Development and Helicobacter pylori‐Related Diseases
10.1186/s12929-018-0480-y · 2018 · External reference
Helicobacter pylori‐Derived Outer Membrane Vesicles Stimulate Interleukin 8 Secretion Through Nuclear Factor Kappa B Activation
10.3904/kjim.2019.432 · 2021 · External reference
The Role of Carbohydrates in the Lipopolysaccharide (LPS)/Toll‐Like Receptor 4 (TLR4) Signalling
10.3390/ijms18112318 · 2017 · External reference
HP‐NAP of Helicobacter pylori: The Power of the Immunomodulation
10.3389/fimmu.2022.944139 · 2022 · External reference
The Hypothesis That Helicobacter pylori Predisposes to Alzheimer's Disease Is Biologically Plausible
10.1038/s41598-017-07532-x · 2017 · External reference
The Gastric Precancerous Cascade
10.1111/j.1751-2980.2011.00550.x · 2012 · External reference
The Neutrophil‐Activating Protein of Helicobacter pylori (HP‐NAP) as an Immune Modulating Agent
10.1111/j.1574-695x.2007.00258.x · 2007 · External reference
TLR2 Regulates Moraxella catarrhalis Adhesion to and Invasion Into Alveolar Epithelial Cells and Mediates Inflammatory Responses
10.1080/21505594.2023.2298548 · 2024 · External reference
Review: Impact of Helicobacter pylori on Alzheimer's Disease: What Do We Know So Far?
10.1111/hel.12454 · 2018 · External reference
Inflammation in Gastric Cancer: Interplay of the COX‐2/Prostaglandin E2 and Toll‐Like Receptor/MyD88 Pathways
10.1111/cas.12901 · 2016 · External reference
Release of Helicobacter pylori Vacuolating Cytotoxin by Both a Specific Secretion Pathway and Budding of Outer Membrane Vesicles. Uptake of Released Toxin and Vesicles by Gastric Epithelium
10.1002/(sici)1096-9896(199906)188:2<220::aid-path307>3.0.co;2-c · 1999 · External reference
TLR10 and Its Unique Anti‐Inflammatory Properties and Potential Use as a Target in Therapeutics
10.4110/in.2020.20.e21 · 2020 · External reference
Helicobacter pylori Neutrophil‐Activating Protein: From Molecular Pathogenesis to Clinical Applications
10.3748/wjg.v20.i18.5294 · 2014 · External reference
The Role of Helicobacter pylori Neutrophil‐Activating Protein in the Pathogenesis of H. pylori and Beyond: From a Virulence Factor to Therapeutic Targets and Therapeutic Agents
10.3390/ijms24010091 · 2022 · External reference
Introduction to NF‐kappaB: Players, Pathways, Perspectives
10.1038/sj.onc.1209954 · 2006 · External reference
Helicobacter pylori Secretes the Chaperonin GroEL (HSP60), Which Binds Iron
10.1016/j.febslet.2013.04.048 · 2013 · External reference
Fucose‐Specific DC‐SIGN Signalling Directs T Helper Cell Type‐2 Responses via IKKε‐ and CYLD‐Dependent Bcl3 Activation
10.1038/ncomms4898 · 2014 · External reference
Anti‐Inflammatory Therapeutic Mechanisms of Isothiocyanates: Insights From Sulforaphane
10.3390/biomedicines12061169 · 2024 · External reference
Cell Surface Trafficking of TLR1 Is Differentially Regulated by the Chaperones PRAT4A and PRAT4B
10.1074/jbc.m112.342717 · 2012 · External reference
Gastric Cancer Originating From Bone Marrow‐Derived Cells
10.1126/science.1099513 · 2004 · External reference
Characterization of Interleukin‐1β in Helicobacter pylori‐Induced Gastric Inflammation and DNA Methylation in Interleukin‐1 Receptor Type 1 Knockout (IL‐1R1(‐/‐)) Mice
10.1016/j.ejca.2013.03.031 · 2013 · External reference
Unresolved reference
External reference
Helicobacter pylori‐Derived Outer Membrane Vesicles (OMVs): Role in Bacterial Pathogenesis?
10.3390/microorganisms8091328 · 2020 · External reference
Bacterial Membrane Vesicles Deliver Peptidoglycan to NOD1 in Epithelial Cells
10.1111/j.1462-5822.2009.01404.x · 2010 · External reference
The Role of Pattern‐Recognition Receptors in Innate Immunity: Update on Toll‐Like Receptors
10.1038/ni.1863 · 2010 · External reference
Differential Role of MyD88 and Mal/TIRAP in TLR2‐Mediated Gastric Tumourigenesis
10.1038/onc.2013.205 · 2014 · External reference
Human Toll‐Like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide
10.1084/jem.188.11.2091 · 1998 · External reference
Correction: Induction of TLR‐2 and TLR‐5 Expression by Helicobacter pylori Switches cagPAI‐Dependent Signalling Leading to the Secretion of IL‐8 and TNF‐alpha
10.1371/journal.pone.0141721 · 2015 · External reference
LPS Quantitation Procedures
10.1007/978-1-4939-0473-0_31 · 2014 · External reference
Effects of Cyclooxygenase‐1 and ‐2 Gene Disruption on Helicobacter pylori‐Induced Gastric Inflammation
10.1086/500984 · 2006 · External reference
Analysis of Relative Gene Expression Data Using Real‐Time Quantitative PCR and the 2(‐Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
H. pylori Eradication With Antibiotic Treatment Causes Changes in Glucose Homeostasis Related to Modifications in the Gut Microbiota
10.1371/journal.pone.0213548 · 2019 · External reference
Proteomic and Functional Characterization of the Outer Membrane Vesicles From the Gastric Pathogen Helicobacter pylori
10.1002/prca.200800192 · 2009 · External reference
Low Biological Activity of Helicobacter pylori Lipopolysaccharide
10.1128/iai.60.4.1714-1716.1992 · 1992 · External reference
Intracellular, Intercellular, and Stromal Invasion of Gastric Mucosa, Preneoplastic Lesions, and Cancer by Helicobacter pylori
10.1053/j.gastro.2007.01.049 · 2007 · External reference
Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil
10.1084/jem.192.11.1601 · 2000 · External reference
MD‐2 Is Necessary for the Toll‐Like Receptor 4 Protein to Undergo Glycosylation Essential for Its Translocation to the Cell Surface
2003 · External reference
Human TLR10 Is an Anti‐Inflammatory Pattern‐Recognition Receptor
2014 · External reference
Activators and Target Genes of Rel/NF‐kappaB Transcription Factors
10.1038/sj.onc.1203239 · 1999 · External reference
Helicobacter pylori Outer Membrane Vesicles Induce Astrocyte Reactivity Through Nuclear Factor‐κappa B Activation and Cause Neuronal Damage In Vivo in a Murine Model
10.1186/s12974-023-02728-7 · 2023 · External reference
Uptake of Helicobacter pylori Outer Membrane Vesicles by Gastric Epithelial Cells
10.1128/iai.00299-10 · 2010 · External reference
Helicobacter pylori: Gastric Cancer and Beyond
10.1038/nrc2857 · 2010 · External reference
Extracellular and Intracellular Pattern Recognition Receptors Cooperate in the Recognition of Helicobacter pylori
10.1053/j.gastro.2009.02.066 · 2009 · External reference
Hyperosmolarity‐Induced AQP5 Upregulation Promotes Inflammation and Cell Death via JNK1/2 Activation in Human Corneal Epithelial Cells
10.1038/s41598-017-05145-y · 2017 · External reference
The Neutrophil‐Activating Protein (HP‐NAP) of Helicobacter pylori Is a Protective Antigen and a Major Virulence Factor
10.1084/jem.191.9.1467 · 2000 · External reference
Expression and Subcellular Distribution of Toll‐Like Receptors TLR4, TLR5 and TLR9 on the Gastric Epithelium in Helicobacter pylori Infection
10.1111/j.1365-2249.2004.02464.x · 2004 · External reference
Accumulation of Somatic Mutations in TP53 in Gastric Epithelium With Helicobacter pylori Infection
10.1053/j.gastro.2014.04.036 · 2014 · External reference
Role of Toll‐Like Receptors in Helicobacter pylori Infection and Immunity
10.4291/wjgp.v5.i3.133 · 2014 · External reference
Differential Modulation of Helicobacter pylori Lipopolysaccharide‐Mediated TLR2 Signaling by Individual Pellino Proteins
10.1111/hel.12325 · 2017 · External reference
NF‐kappaB Signaling in Gastric Cancer
10.3390/toxins9040119 · 2017 · External reference
Helicobacter pylori‐Induced Signaling Pathways Contribute to Intestinal Metaplasia and Gastric Carcinogenesis
2015 · External reference
Epidemiology and Role of Helicobacter pylori Virulence Factors in Gastric Cancer Carcinogenesis
10.1111/apm.13034 · 2020 · External reference
TLR2 Mediates Helicobacter pylori‐Induced Tolerogenic Immune Response in Mice
10.1371/journal.pone.0074595 · 2013 · External reference
NF‐kappaB, Inflammation, Immunity and Cancer: Coming of Age
10.1038/nri.2017.142 · 2018 · External reference
Helicobacter pylori Employs a General Protein Glycosylation System for the Modification of Outer Membrane Adhesins
10.1080/19490976.2022.2130650 · 2022 · External reference
Role of Tumor Necrosis Factor Alpha in Helicobacter pylori Gastritis in Tumor Necrosis Factor Receptor 1‐Deficient Mice
10.1128/iai.70.6.3149-3155.2002 · 2002 · External reference
Membrane Sorting of Toll‐Like Receptor (TLR)‐2/6 and TLR2/1 Heterodimers at the Cell Surface Determines Heterotypic Associations With CD36 and Intracellular Targeting
10.1074/jbc.m602794200 · 2006 · External reference
Helicobacter pylori Outer Membrane Vesicle Size Determines Their Mechanisms of Host Cell Entry and Protein Content
10.3389/fimmu.2018.01466 · 2018 · External reference
Retinoic Acid Synergizes ATO‐Mediated Cytotoxicity by Precluding Nrf2 Activity in AML Cells
10.1038/bjc.2014.380 · 2014 · External reference
Helicobacter pylori‐Induced Inflammation and Epigenetic Changes During Gastric Carcinogenesis
10.3748/wjg.v21.i45.12742 · 2015 · External reference
The Helicobacter pylori Urease Virulence Factor Is Required for the Induction of Hypoxia‐Induced Factor‐1α in Gastric Cells
10.3390/cancers11060799 · 2019 · External reference
Nod1 Responds to Peptidoglycan Delivered by the Helicobacter pylori Cag Pathogenicity Island
10.1038/ni1131 · 2004 · External reference
Phosphorylation of NF‐kappaB and IkappaB Proteins: Implications in Cancer and Inflammation
10.1016/j.tibs.2004.11.009 · 2005 · External reference
Dual Roles of Helicobacter pylori NapA in Inducing and Combating Oxidative Stress
10.1128/iai.00991-06 · 2006 · External reference
Helicobacter pylori Outer Membrane Vesicles and Infected Cell Exosomes: New Players in Host Immune Modulation and Pathogenesis
10.3389/fimmu.2024.1512935 · 2024 · External reference
Helicobacter pylori Neutrophil‐Activating Protein Directly Interacts With and Activates Toll‐Like Receptor 2 to Induce the Secretion of Interleukin‐8 From Neutrophils and ATRA‐Induced Differentiated HL‐60 Cells
10.3390/ijms222111560 · 2021 · External reference
Identification of a TLR2‐Regulated Gene Signature Associated With Tumor Cell Growth in Gastric Cancer
10.1038/onc.2017.121 · 2017 · External reference
Unresolved reference
1965 · External reference
Advances in NF‐kappaB Signaling Transduction and Transcription
2004 · External reference
Suppression of NF‐kappaB and NF‐kappaB‐Regulated Gene Expression by Sulforaphane and PEITC Through IkappaBalpha, IKK Pathway in Human Prostate Cancer PC‐3 Cells
10.1038/sj.onc.1208656 · 2005 · External reference
Highly‐Purified Helicobacter pylori LPS Preparations Induce Weak Inflammatory Reactions and Utilize Toll‐Like Receptor 2 Complex But Not Toll‐Like Receptor 4 Complex
10.1111/j.1574-695x.2007.00288.x · 2007 · External reference
MicroRNA‐3178 Ameliorates Inflammation and Gastric Carcinogenesis Promoted by Helicobacter pylori New Toxin, Tip‐α, by Targeting TRAF3
2017 · External reference