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References from Extracellular Vesicle‐Bound Bacterial Toxin Pneumolysin Triggers Membrane Engagement and Damage Beyond Canonical Pore Formation. Local targets link to admitted publications; unresolved targets remain external evidence.
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Direct Simulation of Protein‐Mediated Vesicle Fusion: Lung Surfactant Protein B
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The Cholesterol‐Dependent Cytolysin Membrane‐Binding Interface Discriminates Lipid Environments of Cholesterol to Support Beta‐Barrel Pore Insertion
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Redefining Cholesterol's Role in the Mechanism of the Cholesterol‐Dependent Cytolysins
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Global, Regional, and National Incidence and Mortality Burden of Non‐COVID‐19 Lower Respiratory Infections and Aetiologies, 1990–2021: A Systematic Analysis From the Global Burden of Disease Study 2021
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Extracellular Vesicles and Nanoparticles: Emerging Complexities
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Cholesterol‐Dependent Cytolysins: The Outstanding Questions
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Ensemble Molecular Dynamics Yields Submillisecond Kinetics and Intermediates of Membrane Fusion
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Coarse‐Grained Molecular Dynamics Study of Membrane Fusion: Curvature Effects on Free Energy Barriers Along the Stalk Mechanism
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Host‐Derived Microvesicles Carrying Bacterial Pore‐Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses
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The Global, Regional, and National Burden of Lower Respiratory Infections Caused by Streptococcus pneumoniae Between 1990 and 2021
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Bacterial Pore‐Forming Toxin Pneumolysin: Cell Membrane Structure and Microvesicle Shedding Capacity Determines Differential Survival of Cell Types
10.1096/fj.201901737rr · 2020 · External reference
Microvesicles Released From Pneumolysin‐Stimulated Lung Epithelial Cells Carry Mitochondrial Cargo and Suppress Neutrophil Oxidative Burst
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The Mechanism of Vesicle Fusion as Revealed by Molecular Dynamics Simulations
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10.1002/jcc.21787 · 2011 · External reference
Bacterial Pore‐Forming Toxin Pneumolysin Drives Pathogenicity Through Host Extracellular Vesicles Released During Infection
10.1016/j.isci.2024.110589 · 2024 · External reference
Purification and Immunogenicity of Genetically Obtained Pneumolysin Toxoids and Their Conjugation to Streptococcus pneumoniae Type 19F Polysaccharide
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Cholesterol‐Sphingomyelin Interactions: A Molecular Dynamics Simulation Study
10.1529/biophysj.106.080887 · 2006 · External reference
Cholesterol Effects on a Mixed‐Chain Phosphatidylcholine Bilayer: A Molecular Dynamics Simulation Study
10.1016/j.biochi.2005.10.005 · 2006 · External reference
Physicochemical Characterization of Liposomes That Mimic the Lipid Composition of Exosomes for Effective Intracellular Trafficking
10.1021/acs.langmuir.0c02491 · 2020 · External reference
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10.1093/nar/gkab409 · 2021 · External reference
The Cholesterol‐Dependent Cytolysins Pneumolysin and Streptolysin O Require Binding to Red Blood Cell Glycans for Hemolytic Activity
2014 · External reference
Structural Basis of Pore Formation by the Bacterial Toxin Pneumolysin
10.1016/j.cell.2005.02.033 · 2005 · External reference
CryoEM Structures of Membrane Pore and Prepore Complex Reveal Cytolytic Mechanism of Pneumolysin
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Membrane Perforation by the Pore‐Forming Toxin Pneumolysin
10.1073/pnas.1904304116 · 2019 · External reference
Active Release of Pneumolysin Prepores and Pores by Mammalian Cells Undergoing a Streptococcus pneumoniae Attack
10.1016/j.bbagen.2016.07.022 · 2016 · External reference