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References from Phytochemical profiling and bioactivity of <scp> <i>Rhaponticoides mykalea</i> </scp> : <i>α</i> ‐glucosidase inhibition, apoptosis‐associated cytotoxicity, and <scp> <i>in silico</i> </scp> molecular insights. Local targets link to admitted publications; unresolved targets remain external evidence.
Endometrial cancer
10.1016/s0140-6736(22)00323-3 · 2022 · External reference
Drug resistance in cancer: molecular mechanisms and emerging treatment strategies
10.1186/s43556-025-00352-w · 2025 · External reference
Targeting apoptosis in cancer therapy
10.1038/s41571-020-0341-y · 2020 · External reference
Cancer and apoptosis: the apoptotic activity of plant and marine natural products and their potential as targeted cancer therapeutics
10.3389/fphar.2022.842376 · 2022 · External reference
Oxidative stress in metabolic diseases: current scenario and therapeutic relevance
10.1007/s11010-022-04496-z · 2023 · External reference
Recent updates on phytoconstituent alpha‐glucosidase inhibitors: an approach towards the treatment of type two diabetes
2022 · External reference
Unresolved reference
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1988 · External reference
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2012 · External reference
Evaluation of the chemical composition, antioxidant and antidiabetic activity of Rhaponticoides iconiensis flowers: effects on key enzymes linked to type 2 diabetes in vitro, in silico and on alloxan‐induced diabetic rats in vivo
10.3390/antiox11112284 · 2022 · External reference
Chemical composition, in vitro antioxidant, and antidiabetic potential of essential oil from flowers of Rhaponticoides iconiensis
10.1080/0972060x.2022.2158761 · 2022 · External reference
Hypoglycemic, antioxidant, antimicrobial activities and phytochemical analyses of Rhaponticoides iconiensis leafy stem extracts
10.1007/s42535-021-00250-w · 2021 · External reference
Identification of bioactive compounds from Rhaponticoides iconiensis extracts and their bioactivities: an endemic plant to Turkey flora
10.1016/j.jpba.2020.113537 · 2020 · External reference
Phytochemical composition, in vitro antimicrobial, antioxidant, and enzyme inhibition activities, and in silico molecular docking and dynamics simulations of Centaurea lycaonica: a computational and experimental approach
10.1021/acsomega.3c01819 · 2023 · External reference
10.1016/j.fbio.2025.105923
10.1016/j.fbio.2025.105923 · External reference
Assessment of the antioxidant and enzyme inhibition activities of Cousinia iconica with focus on phytochemical investigation by LC‐MS/MS
2021 · External reference
Chemical composition and biological activity of the essential oil from Eryngium kotschyi Boiss
10.1080/0972060x.2023.2265959 · 2023 · External reference
Comprehensive evaluation of Pulicaria dysenterica subsp. dysenterica decoction: phenolic profile by UHPLC‐HESI‐orbitrap®‐HRMS2, in vitro gastrointestinal stability of biological activities, acute oral toxicity, and antihemorrhoidal potential
10.1016/j.jep.2026.121700 · 2026 · External reference
Phytochemical profiling and molecular insights of Centaurea lycaonica: apoptosis induction via the intrinsic pathway in endometrial cancer cells
10.3390/ph18101558 · 2025 · External reference
Inhibitory effects of syringic acid on endometrial cancer cell growth and migration and its synergistic suppression with doxorubicin
10.3390/ph18111596 · 2025 · External reference
Unresolved reference
2025 · External reference
Flavonoids from the Turkish endemic plant Rhaponticoides mykalea (Hub.‐Mor.) MV Agab. & Greuter (Asteraceae)
10.1016/j.bse.2021.104288 · 2021 · External reference
Natural products as α‐amylase and α‐glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update
10.2174/138955710791331007 · 2010 · External reference
Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α‐amylase and α‐glucosidase activity: a review
10.1080/10408398.2020.1862755 · 2022 · External reference
Chemical profile, antioxidant and cytotoxic activity of a phenolic‐rich fraction from the leaves of Brassica fruticulosa subsp. fruticulosa (Brassicaceae) growing wild in Sicily (Italy)
10.3390/molecules28052281 · 2023 · External reference
BAX‐dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis
10.1007/s10495-020-01627-z · 2020 · External reference
Comparative evaluation of cytotoxicity and phytochemical composition of Centaurea iconiensis (Rhaponticoides iconiensis)
10.1007/s40995-020-01030-y · 2021 · External reference
Redox activity of flavonoids: impact on human health, therapeutics, and chemical safety
10.1021/acs.chemrestox.1c00348 · 2022 · External reference
Active compounds, antioxidant activity and α‐glucosidase inhibitory activity of different varieties of Chaenomeles fruits
10.1016/j.foodchem.2017.12.018 · 2018 · External reference
Flavonoids as alpha‐glucosidase inhibitors: mechanistic approaches merged with enzyme kinetics and molecular modelling
10.1007/s11101-019-09610-6 · 2020 · External reference
Inhibition mechanism of ferulic acid against α‐amylase and α‐glucosidase
10.1016/j.foodchem.2020.126346 · 2020 · External reference
Chlorogenic acid ameliorates mice clinical endometritis by activating Keap1/Nrf2 and inhibiting NFκB signalling pathway
10.1093/jpp/rgab020 · 2021 · External reference
Chlorogenic acid alleviates hepatic ischemia–reperfusion injury by inhibiting oxidative stress, inflammation, and mitochondria‐mediated apoptosis in vivo and in vitro
10.1007/s10753-023-01792-8 · 2023 · External reference
Centaurea lycaonica extracts induce apoptosis in HeLa human cervical cancer cells via Bax/Bcl‐2 modulation and caspase activation: an LC‐HRMS‐based study
10.1002/fsn3.70528 · 2025 · External reference
Bcl‐2 modulation in p53 signaling pathway by flavonoids: a potential strategy towards the treatment of cancer
10.3390/ijms222111315 · 2021 · External reference
Induction of apoptosis by luteolin through cleavage of Bcl‐2 family in human leukemia HL‐60 cells
10.1016/j.ejphar.2004.12.026 · 2005 · External reference
Direct plant regeneration from different explants through micropropagation and determination of secondary metabolites in the critically endangered endemic Rhaponticoides mykalea
2017 · External reference
Mechanisms of BCL‐2 family proteins in mitochondrial apoptosis
10.1038/s41580-023-00629-4 · 2023 · External reference
A hierarchical approach to all‐atom protein loop prediction
10.1002/prot.10613 · 2004 · External reference
Essential oils from Salvia marashica and Salvia multicaulis as natural ingredients: phytochemical composition, antioxidant activity, enzyme inhibition, and molecular docking studies
10.1007/s11694-026-04563-9 · 2026 · External reference