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References from CNOT4 Suppresses Bladder Cancer Progression by Promoting Ubiquitination‐Mediated Degradation of EIF2AK2 and Inhibiting Autophagy. Local targets link to admitted publications; unresolved targets remain external evidence.
The Global Landscape of Bladder Cancer Incidence and Mortality in 2020 and Projections to 2040
10.7189/jogh.13.04109 · 2023 · External reference
Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2024 · External reference
European Association of Urology Guidelines on Muscle‐Invasive and Metastatic Bladder Cancer: Summary of the 2025 Guidelines
10.1016/j.eururo.2025.02.019 · 2025 · External reference
Management of Clinical Stage T3/T4 Bladder Cancer: A Review
10.1007/s00345-025-05960-3 · 2025 · External reference
Patients With Metastatic or Locally Advanced Bladder Cancer Not Undergoing Systemic Oncological Treatment‐Characteristics and Long‐Term Outcome in a Single‐Center Danish Cohort
10.3390/cancers17071105 · 2025 · External reference
Ubiquitination and Deubiquitination in Cancer: From Mechanisms to Novel Therapeutic Approaches
10.1186/s12943-024-02046-3 · 2024 · External reference
Ubiquitin‐Regulated Cell Proliferation and Cancer
10.1007/978-3-030-38266-7_1 · 2020 · External reference
Deubiquitinating Enzymes (DUBs): Regulation, Homeostasis, and Oxidative Stress Response
10.1016/j.jbc.2021.101077 · 2021 · External reference
Structural Diversity of Ubiquitin E3 Ligase
10.3390/molecules26216682 · 2021 · External reference
E3 Ubiquitin Ligases and Deubiquitinases in Bladder Cancer Tumorigenesis and Implications for Immunotherapies
10.3389/fimmu.2023.1226057 · 2023 · External reference
RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer
10.1002/advs.202408311 · 2025 · External reference
TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling
10.1158/1541-7786.mcr-20-1029 · 2022 · External reference
Regulated Cell Death (RCD) in Cancer: Key Pathways and Targeted Therapies
10.1038/s41392-022-01110-y · 2022 · External reference
Autophagy‐Dependent Cell Death ‐ Where, How and Why a Cell Eats Itself to Death
10.1242/jcs.215152 · 2018 · External reference
Autophagy as a Decisive Process for Cell Death
10.1038/s12276-020-0455-4 · 2020 · External reference
Autophagy Flux in Bladder Cancer: Cell Death Crosstalk, Drug and Nanotherapeutics
10.1016/j.canlet.2024.216867 · 2024 · External reference
EIF2AK2 Selectively Regulates the Gene Transcription in Immune Response and Histones Associated With Systemic Lupus Erythematosus
10.1016/j.molimm.2021.01.030 · 2021 · External reference
EIF2A Promotes Cell Survival During Paclitaxel Treatment in Vitro and In Vivo
10.1111/jcmm.14469 · 2019 · External reference
Discovery and Identification of EIF2AK2 as a Direct Key Target of Berberine for Anti‐Inflammatory Effects
10.1016/j.apsb.2022.12.009 · 2023 · External reference
Direct Interaction Between STAT3 and EIF2AK2 Controls Fatty Acid‐Induced Autophagy
10.4161/auto.22910 · 2013 · External reference
10.1007/s10266-025-01298-9
10.1007/s10266-025-01298-9 · External reference
Double Stranded RNA‐Dependent Protein Kinase Promotes the Tumorigenic Phenotype in HepG2 Hepatocellular Carcinoma Cells by Activating STAT3
10.3892/ol.2014.2560 · 2014 · External reference
Eukaryotic Translation Initiation Factor 2α Kinase 2 in Pancreatic Cancer: An Approach Towards Managing Clinical Prognosis and Molecular Immunological Characterization
10.3892/ol.2023.14066 · 2023 · External reference
Characterization of an Autophagy‐Immune Related Genes Score Signature and Prognostic Model and Its Correlation With Immune Response for Bladder Cancer
10.2147/cmar.s346240 · 2022 · External reference
JNK Signaling Mediates Acute Rejection via Activating Autophagy of CD8(+) T Cells After Liver Transplantation in Rats
10.3389/fimmu.2024.1359859 · 2024 · External reference
ERK and Cell Death: Mechanisms of Erk‐Induced Cell Death‐‐Apoptosis, Autophagy and Senescence
10.1111/j.1742-4658.2009.07366.x · 2010 · External reference
Oncogenic RAS Induces a Distinctive Form of Non‐Canonical Autophagy Mediated by the p38‐ULK1‐PI4KB Axis
10.1038/s41422-025-01085-9 · 2025 · External reference
Insights into the Structure and Architecture of the CCR4‐NOT Complex
2014 · External reference
CNOT4 Suppresses Nonsmall Cell Lung Cancer Progression by Promoting the Degradation of PAF1
10.1002/mc.23599 · 2023 · External reference
CNOT4 Suppresses Non‐Small Cell Lung Cancer Progression and Is Required for Effector Cytolytic T Lymphocytes Cell Responses to Lung Cancer Cells
10.1016/j.molimm.2020.12.020 · 2021 · External reference
CNOT4 Enhances the Efficacy of Anti‐PD‐1 Immunotherapy in a Model of Non‐Small Cell Lung Cancer
10.1002/2211-5463.12998 · 2020 · External reference
Depletion of CNOT4 Modulates the DNA Damage Responses Following Ionizing Radiation (IR)
10.4103/jcrt.jcrt_1723_22 · 2024 · External reference
Interferon and Interferon‐Inducible Gene Activation in Patients With Type 1 Diabetes
10.1111/sji.12204 · 2014 · External reference