Research graph
References from Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies. Local targets link to admitted publications; unresolved targets remain external evidence.
Metastasis
10.1016/j.cell.2023.03.003 · 2023 · External reference
10.1016/b978-0-323-90195-6.00002-4
10.1016/b978-0-323-90195-6.00002-4 · 2022 · External reference
Multi‐Stage Mechanisms of Tumor Metastasis and Therapeutic Strategies
10.1038/s41392-024-01955-5 · 2024 · External reference
A Recipe for Successful Metastasis: Transition and Migratory Modes of Ovarian Cancer Cells
10.3390/cancers16040783 · 2024 · External reference
The Distribution of Secondary Growths in Cancer of THE Breast
10.1016/s0140-6736(00)49915-0 · 1889 · External reference
Tumors: Wounds That Do Not Heal. Similarities Between Tumor Stroma Generation and Wound Healing
10.1056/nejm198612253152606 · 1986 · External reference
VEGFR1‐Positive Haematopoietic Bone Marrow Progenitors Initiate the Pre‐Metastatic Niche
10.1038/nature04186 · 2005 · External reference
Multistep Nature of Metastatic Inefficiency: Dormancy of Solitary Cells After Successful Extravasation and Limited Survival of Early Micrometastases
10.1016/s0002-9440(10)65628-3 · 1998 · External reference
Real‐time Imaging Reveals the Single Steps of Brain Metastasis Formation
10.1038/nm.2072 · 2010 · External reference
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
10.1016/j.cell.2014.07.013 · 2014 · External reference
Identification of the Tumour Transition States Occurring During EMT
10.1038/s41586-018-0040-3 · 2018 · External reference
Decoding the Interplay Between Genetic and Non‐Genetic Drivers of Metastasis
10.1038/s41586-024-07302-6 · 2024 · External reference
A Multi‐Modal Single‐Cell and Spatial Expression Map of Metastatic Breast Cancer Biopsies Across Clinicopathological Features
10.1038/s41591-024-03215-z · 2024 · External reference
Pan‐Cancer Whole‐Genome Analyses of Metastatic Solid Tumours
10.1038/s41586-019-1689-y · 2019 · External reference
Pan‐Cancer Whole‐Genome Comparison of Primary and Metastatic Solid Tumours
10.1038/s41586-023-06054-z · 2023 · External reference
Immune Checkpoint HLA‐E:CD94‐NKG2A Mediates Evasion of Circulating Tumor Cells From NK Cell Surveillance
10.1016/j.ccell.2023.01.001 · 2023 · External reference
Single‐Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma
10.1002/advs.202204565 · 2023 · External reference
Integrating Model Systems and Genomic Insights to Decipher Mechanisms of Cancer Metastasis
10.1038/s41576-025-00825-2 · 2025 · External reference
Early Dissemination Seeds Metastasis in Breast Cancer
10.1038/nature20785 · 2016 · External reference
Single‐cell Lineages Reveal the Rates, Routes, and Drivers of Metastasis in Cancer Xenografts
10.1126/science.abc1944 · 2021 · External reference
The Evolution of Non‐Small Cell Lung Cancer Metastases in TRACERx
10.1038/s41586-023-05729-x · 2023 · External reference
Cancer Genome Evolutionary Trajectories in Metastasis
10.1016/j.ccell.2019.12.004 · 2020 · External reference
Genomic Evolution of Breast Cancer Metastasis and Relapse
10.1016/j.ccell.2017.07.005 · 2017 · External reference
Rare Subclonal Sequencing of Breast Cancers Indicates Putative Metastatic Driver Mutations Are Predominately Acquired After Dissemination
10.1186/s13073-024-01293-9 · 2024 · External reference
Loss of Kmt2c or Kmt2d Drives Brain Metastasis via KDM6A‐Dependent Upregulation of MMP3
10.1038/s41556-024-01446-3 · 2024 · External reference
Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness
10.1016/j.gastha.2024.04.005 · 2024 · External reference
Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis
10.1016/j.cell.2017.07.007 · 2017 · External reference
Genomic Characterization of Metastatic Patterns From Prospective Clinical Sequencing of 25,000 Patients
10.1016/j.cell.2022.01.003 · 2022 · External reference
Longitudinal and Multisite Sampling Reveals Mutational and Copy Number Evolution in Tumors During Metastatic Dissemination
10.1038/s41588-025-02204-3 · 2025 · External reference
Genomic and Evolutionary Characteristics of Metastatic Gastric Cancer by Routes
10.1038/s41416-023-02338-3 · 2023 · External reference
Evolutionary Characterization of Lung Cancer Metastasis
10.1038/s41586-026-10428-4 · 2026 · External reference
Mapping Extrachromosomal DNA Amplifications During Cancer Progression
10.1038/s41588-024-01949-7 · 2024 · External reference
Origins and Impact of Extrachromosomal DNA
10.1038/s41586-024-08107-3 · 2024 · External reference
Epigenetic Regulation During Cancer Transitions Across 11 Tumour Types
10.1038/s41586-023-06682-5 · 2023 · External reference
The Chromatin Accessibility Landscape of Primary Human Cancers
10.1126/science.aav1898 · 2018 · External reference
Nfib Promotes Metastasis Through a Widespread Increase in Chromatin Accessibility
10.1016/j.cell.2016.05.052 · 2016 · External reference
Epigenomic Reprogramming During Pancreatic Cancer Progression Links Anabolic Glucose Metabolism to Distant Metastasis
10.1038/ng.3753 · 2017 · External reference
Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
10.1016/j.ccell.2020.06.006 · 2020 · External reference
TGF‐β and RAS Jointly Unmask Primed Enhancers to Drive Metastasis
10.1016/j.cell.2024.08.014 · 2024 · External reference
Temporal Chromatin Accessibility Changes Define Transcriptional States Essential for Osteosarcoma Metastasis
10.1038/s41467-023-42656-x · 2023 · External reference
The Evolving Tumor Microenvironment: From Cancer Initiation to Metastatic Outgrowth
10.1016/j.ccell.2023.02.016 · 2023 · External reference
Metabolic Heterogeneity in Cancer
10.1038/s42255-023-00963-z · 2024 · External reference
Spatial Single‐Cell Isotope Tracing Reveals Heterogeneity of De Novo Fatty Acid Synthesis in Cancer
10.1038/s42255-024-01118-4 · 2024 · External reference
Hypoxia‐inducible Factor‐Dependent ADAM12 Expression Mediates Breast Cancer Invasion and Metastasis
10.1073/pnas.2020490118 · 2021 · External reference
Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells
10.1016/j.celrep.2020.108105 · 2020 · External reference
Hypoxic Colorectal Cancer Cells Promote Metastasis of Normoxic Cancer Cells Depending on IL‐8/p65 Signaling Pathway
10.1038/s41419-020-02797-z · 2020 · External reference
Fate‐Mapping Post‐Hypoxic Tumor Cells Reveals a ROS‐resistant Phenotype That Promotes Metastasis
10.1038/s41467-019-12412-1 · 2019 · External reference
Hypoxia Induces ROS‐Resistant Memory Upon Reoxygenation in Vivo Promoting Metastasis in Part via MUC1‐C
10.1038/s41467-024-51995-2 · 2024 · External reference
Lactate Promotes Metastasis of Normoxic Colorectal Cancer Stem Cells Through PGC‐1α‐Mediated Oxidative Phosphorylation
10.1038/s41419-022-05111-1 · 2022 · External reference
Lactate Controls Cancer Stemness and Plasticity Through Epigenetic Regulation
10.1016/j.cmet.2025.01.002 · 2025 · External reference
Snail Reprograms Glucose Metabolism by Repressing Phosphofructokinase PFKP Allowing Cancer Cell Survival Under Metabolic Stress
10.1038/ncomms14374 · 2017 · External reference
mTOR Repression in Response to Amino Acid Starvation Promotes ECM Degradation Through MT1‐MMP Endocytosis Arrest
10.1002/advs.202101614 · 2021 · External reference
TFEB Triggers a Matrix Degradation and Invasion Program in Triple‐Negative Breast Cancer Cells Upon mTORC1 Repression
10.1016/j.devcel.2024.12.005 · 2025 · External reference
10.1371/journal.pbio.3002406 · 2024 · Admitted local publication
Matrix Stiffness Drives Epithelial‐Mesenchymal Transition and Tumour Metastasis Through a TWIST1‐G3BP2 Mechanotransduction Pathway
10.1038/ncb3157 · 2015 · External reference
Matrix Stiffening Facilitates Stemness of Liver Cancer Stem Cells by YAP Activation and BMF Inhibition
10.1016/j.bioadv.2024.213936 · 2024 · External reference
Niche Stiffness Sustains Cancer Stemness via TAZ and NANOG Phase Separation
10.1038/s41467-023-35856-y · 2023 · External reference
Confined Migration Promotes Cancer Metastasis Through Resistance to Anoikis and Increased Invasiveness
10.7554/elife.73150 · 2022 · External reference
Extracellular Matrix‐Derived Mechanical Force Governs Breast Cancer Cell Stemness and Quiescence Transition Through Integrin‐DDR Signaling
10.1038/s41392-023-01453-0 · 2023 · External reference
Matrix Mechano‐sensing at the Invasive front Induces a Cytoskeletal and Transcriptional Memory Supporting Metastasis
10.1038/s41467-025-56299-7 · 2025 · External reference
A Mechanosensitive Caveolae‐Invadosome Interplay Drives Matrix Remodelling for Cancer Cell Invasion
10.1038/s41556-023-01272-z · 2023 · External reference
Cancer‐Associated Fibroblast‐Derived SOD3 Enhances Lymphangiogenesis to Drive Metastasis in Lung Adenocarcinoma
10.1007/s10456-025-10005-9 · 2025 · External reference
Cancer‐Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA‐Dependent Microenvironmental Remodeling to Support Colorectal Cancer
10.1158/0008-5472.can-23-3987 · 2024 · External reference
PDGFRα(+)ITGA11(+) Fibroblasts Foster Early‐Stage Cancer Lymphovascular Invasion and Lymphatic Metastasis via ITGA11‐SELE Interplay
10.1016/j.ccell.2024.02.002 · 2024 · External reference
An HGF‐Dependent Positive Feedback Loop Between Bladder Cancer Cells and Fibroblasts Mediates Lymphangiogenesis and Lymphatic Metastasis
10.1002/cac2.12470 · 2023 · External reference
Pancreatic Stellate Cells Support Tumour Metabolism Through Autophagic Alanine Secretion
10.1038/nature19084 · 2016 · External reference
Axon Guidance Molecules Promote Perineural Invasion and Metastasis of Orthotopic Pancreatic Tumors in Mice
10.1053/j.gastro.2019.05.065 · 2019 · External reference
Nociceptive Neurons Promote Gastric Tumour Progression via a CGRP‐RAMP1 Axis
10.1038/s41586-025-08591-1 · 2025 · External reference
Neuronal Substance P Drives Metastasis Through an Extracellular RNA‐TLR7 Axis
10.1038/s41586-024-07767-5 · 2024 · External reference
Nerve‐to‐Cancer Transfer of Mitochondria During Cancer Metastasis
10.1038/s41586-025-09176-8 · 2025 · External reference
Schwann Cells Regulate Tumor Cells and Cancer‐Associated Fibroblasts in the Pancreatic Ductal Adenocarcinoma Microenvironment
10.1038/s41467-023-40314-w · 2023 · External reference
Schwann Cells Augment Cell Spreading and Metastasis of Lung Cancer
10.1158/0008-5472.can-18-1702 · 2018 · External reference
Autophagic Schwann Cells Promote Perineural Invasion Mediated by the NGF/ATG7 Paracrine Pathway in Pancreatic Cancer
10.1186/s13046-021-02198-w · 2022 · External reference
Dietary Palmitic Acid Promotes a Prometastatic Memory via Schwann Cells
10.1038/s41586-021-04075-0 · 2021 · External reference
Neoantigen‐directed Immune Escape in Lung Cancer Evolution
10.1038/s41586-019-1032-7 · 2019 · External reference
Neoantigen Quality Predicts Immunoediting in Survivors of Pancreatic Cancer
10.1038/s41586-022-04735-9 · 2022 · External reference
The Hippo‐YAP Signaling Pathway Drives CD24‐Mediated Immune Evasion in Esophageal Squamous Cell Carcinoma via Macrophage Phagocytosis
10.1038/s41388-023-02923-z · 2024 · External reference
Lymphatic‐Localized Treg‐mregDC Crosstalk Limits Antigen Trafficking and Restrains Anti‐Tumor Immunity
10.1016/j.ccell.2024.06.014 · 2024 · External reference
VEGF‐C Promotes Immune Tolerance in B16 Melanomas and Cross‐Presentation of Tumor Antigen by Lymph Node Lymphatics
10.1016/j.celrep.2012.01.005 · 2012 · External reference
A Paracrine Loop Between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors
10.1158/0008-5472.can-04-1449 · 2004 · External reference
Macrophage‐Dependent Tumor Cell Transendothelial Migration Is Mediated by Notch1/Mena(INV)‐initiated Invadopodium Formation
10.1038/srep37874 · 2016 · External reference
Mesothelin Secretion by Pancreatic Cancer Cells Co‐Opts Macrophages and Promotes Metastasis
10.1158/0008-5472.can-23-1542 · 2024 · External reference
Necroptosis Enhances 'Don't Eat Me' Signal and Induces Macrophage Extracellular Traps to Promote Pancreatic Cancer Liver Metastasis
10.1038/s41467-024-50450-6 · 2024 · External reference
Real‐Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage‐Derived VEGFA
10.1158/2159-8290.cd-15-0012 · 2015 · External reference
Targeting CSF‐1 Signaling Between Tumor Cells and Macrophages at TMEM Doorways Inhibits Breast Cancer Dissemination
10.1038/s41388-025-03485-y · 2025 · External reference
ETV4 Mediated Tumor‐Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer
10.1002/advs.202205613 · 2023 · External reference
Regulatory T Cells Crosstalk With Tumor Cells and Endothelium Through Lymphotoxin Signaling
10.1038/s41467-024-54874-y · 2024 · External reference
Preexisting Commensal Dysbiosis Is a Host‐Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor‐Positive Breast Cancer
10.1158/0008-5472.can-18-3464 · 2019 · External reference
A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β‐Catenin Axes
10.1158/2159-8290.cd-20-0537 · 2021 · External reference
Fusobacterium Nucleatum Host‐Cell Binding and Invasion Induces IL‐8 and CXCL1 Secretion That Drives Colorectal Cancer Cell Migration
10.1126/scisignal.aba9157 · 2020 · External reference
Fusobacterium Nucleatum Reduces METTL3‐mediated M(6)A Modification and Contributes to Colorectal Cancer Metastasis
10.1038/s41467-022-28913-5 · 2022 · External reference
Colibactin‐Producing Escherichia Coli Enhance Resistance to Chemotherapeutic Drugs by Promoting Epithelial to Mesenchymal Transition and Cancer Stem Cell Emergence
10.1080/19490976.2024.2310215 · 2024 · External reference
Microbiota Enterotoxigenic Bacteroides Fragilis‐Secreted BFT‐1 Promotes Breast Cancer Cell Stemness and Chemoresistance Through Its Functional Receptor NOD1
10.1093/procel/pwae005 · 2024 · External reference
The Colibactin‐Producing Escherichia coli Alters the Tumor Microenvironment to Immunosuppressive Lipid Overload Facilitating Colorectal Cancer Progression and Chemoresistance
10.1080/19490976.2024.2320291 · 2024 · External reference
Breast Cancer Colonization by Fusobacterium Nucleatum Accelerates Tumor Growth and Metastatic Progression
10.1038/s41467-020-16967-2 · 2020 · External reference
Intratumoral Fusobacterium Nucleatum Recruits Tumor‐Associated Neutrophils to Promote Gastric Cancer Progression and Immune Evasion
10.1158/0008-5472.can-24-2580 · 2025 · External reference
Intracellular Fusobacterium Nucleatum Infection Attenuates Antitumor Immunity in Esophageal Squamous Cell Carcinoma
10.1038/s41467-023-40987-3 · 2023 · External reference
Tumor‐resident Intracellular Microbiota Promotes Metastatic Colonization in Breast Cancer
10.1016/j.cell.2022.02.027 · 2022 · External reference
Fusobacterium Nucleatum Promotes Tumor Extravasation and Metastasis in Head and Neck Cancer via TLR4/MYB/ESPN Axis
10.1038/s42003-026-09913-3 · 2026 · External reference
Gut Vascular Barrier Impairment Leads to Intestinal Bacteria Dissemination and Colorectal Cancer Metastasis to Liver
10.1016/j.ccell.2021.03.004 · 2021 · External reference
Lactate Production by Tumor‐Resident Staphylococcus Promotes Metastatic Colonization in Lung Adenocarcinoma
10.1016/j.chom.2025.06.013 · 2025 · External reference
Tumor Cell Migration in Complex Microenvironments
10.1007/s00018-012-1115-1 · 2013 · External reference
Metabolic Reprogramming and Therapeutic Resistance in Primary and Metastatic Breast Cancer
10.1186/s12943-024-02165-x · 2024 · External reference
Spatial Transcriptomic Analysis of Primary and Metastatic Pancreatic Cancers Highlights Tumor Microenvironmental Heterogeneity
10.1038/s41588-024-01914-4 · 2024 · External reference
Tumor Microenvironment Crosstalk Between Tumors and the Nervous System in Pancreatic Cancer: Molecular Mechanisms and Clinical Perspectives
2024 · External reference
Cancer‐induced Systemic Pre‐Conditioning of Distant Organs: Building a Niche for Metastatic Cells
10.1038/s41568-024-00752-0 · 2024 · External reference
Liver Metastasis in Cancer: Molecular Mechanisms and Management
10.1002/mco2.70119 · 2025 · External reference
The Temporal Progression of Lung Immune Remodeling During Breast Cancer Metastasis
10.1016/j.ccell.2024.05.004 · 2024 · External reference
Evolving Cancer‐Niche Interactions and Therapeutic Targets During Bone Metastasis
10.1038/s41568-021-00406-5 · 2022 · External reference
NFE2‐Driven Neutrophil Polarization Promotes Pancreatic Cancer Liver Metastasis Progression
10.1016/j.celrep.2024.115226 · 2025 · External reference
Spatial Immune Remodeling of the Liver Metastases: Discovering the Path to Antimetastatic Therapy
10.1136/jitc-2024-011002 · 2025 · External reference
Reprogramming Anchorage Dependency by Adherent‐to‐Suspension Transition Promotes Metastatic Dissemination
10.1186/s12943-023-01753-7 · 2023 · External reference
Brief Pulses of High‐Level Fluid Shear Stress Enhance Metastatic Potential and Rapidly Alter the Metabolism of Cancer Cells
10.1016/j.celrep.2025.116908 · 2026 · External reference
Cancer Cells Resist Mechanical Destruction in Circulation via RhoA/Actomyosin‐Dependent Mechano‐Adaptation
10.1016/j.celrep.2020.02.080 · 2020 · External reference
Metastatic Breast Cancer Cells Are Metabolically Reprogrammed to Maintain Redox Homeostasis During Metastasis
10.1016/j.redox.2024.103276 · 2024 · External reference
Neutrophils Escort Circulating Tumour Cells to Enable Cell Cycle Progression
10.1038/s41586-019-0915-y · 2019 · External reference
Oxidative Stress Inhibits Distant Metastasis by Human Melanoma Cells
10.1038/nature15726 · 2015 · External reference
Platelet‐Mediated Circulating Tumor Cell Evasion From Natural Killer Cell Killing Through Immune Checkpoint CD155‐TIGIT
10.1097/hep.0000000000000934 · 2025 · External reference
Breast Cancer Remodels Lymphatics in Sentinel Lymph Nodes
10.1038/s41467-025-64981-z · 2025 · External reference
Dynamic CD8(+) T Cell Responses to Cancer Immunotherapy in human Regional Lymph Nodes Are Disrupted in Metastatic Lymph Nodes
10.1016/j.cell.2023.02.021 · 2023 · External reference
Fatty Acid Oxidation Supports Lymph Node Metastasis of Cervical Cancer via Acetyl‐CoA‐Mediated Stemness
10.1002/advs.202308422 · 2024 · External reference
Lymph Node Colonization Induces Tissue Remodeling via Immunosuppressive Fibroblast‐Myeloid Cell Niches Supporting Metastatic Tolerance
10.1016/j.ccell.2026.01.003 · 2026 · External reference
Lymph Protects Metastasizing Melanoma Cells From Ferroptosis
10.1038/s41586-020-2623-z · 2020 · External reference
Single‐Cell Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity in Primary and Lymph Node‐Metastatic Small Cell Lung Cancer
10.1016/j.xcrm.2026.102713 · 2026 · External reference
Solid Stress Impairs Lymphocyte Infiltration Into Lymph‐Node Metastases
10.1038/s41551-021-00766-1 · 2021 · External reference
Cancer‐Associated Fibroblasts Foster a High‐Lactate Microenvironment to Drive Perineural Invasion in Pancreatic Cancer
10.1158/0008-5472.can-24-3173 · 2025 · External reference
Cancer‐induced Nerve Injury Promotes Resistance to Anti‐PD‐1 Therapy
10.1038/s41586-025-09370-8 · 2025 · External reference
Inflammatory Monocytes Promote Perineural Invasion via CCL2‐Mediated Recruitment and Cathepsin B Expression
10.1158/0008-5472.can-17-1612 · 2017 · External reference
Nociceptor Neurons Promote PDAC Progression and Cancer Pain by Interaction With Cancer‐Associated Fibroblasts and Suppression of Natural Killer Cells
10.1038/s41422-025-01098-4 · 2025 · External reference
Rapid Cancer Cell Perineural Invasion Utilizes Amoeboid Migration
10.1073/pnas.2210735120 · 2023 · External reference
Reprogrammed Schwann Cells Organize Into Dynamic Tracks That Promote Pancreatic Cancer Invasion
10.1158/2159-8290.cd-21-1690 · 2022 · External reference
Molecular Mechanisms of Cell Death: Recommendations of the Nomenclature Committee on Cell Death 2018
10.1038/s41418-017-0012-4 · 2018 · External reference
MFG‐E8 Induces Epithelial‐Mesenchymal Transition and Anoikis Resistance to Promote the Metastasis of Pancreatic Cancer Cells
10.1016/j.ejphar.2024.176462 · 2024 · External reference
ATF4/CEMIP/PKCα Promotes Anoikis Resistance by Enhancing Protective Autophagy in Prostate Cancer Cells
10.1038/s41419-021-04494-x · 2022 · External reference
Drp1 Interaction With BIP Maintains Mitochondrial Dynamic Equilibrium to Promote Anoikis Resistance and Metastasis in Nasopharyngeal Carcinoma
10.1158/0008-5472.can-25-0622 · 2026 · External reference
A Noncanonical Role of SAT1 Enables Anchorage Independence and Peritoneal Metastasis in Ovarian Cancer
10.1038/s41467-025-58525-8 · 2025 · External reference
YEATS2 Promotes DNA Repair and Induces Anoikis Resistance by Enhancing Chromatin Accessibility to Drive Prostate Cancer Metastasis
10.1038/s41388-026-03696-x · 2026 · External reference
Fluid Shear Stress Enhances Natural Killer Cell's Cytotoxicity Toward Circulating Tumor Cells Through NKG2D‐Mediated Mechanosensing
10.1063/5.0156628 · 2023 · External reference
Fluids and Their Mechanics in Tumour Transit: Shaping Metastasis
10.1038/s41568-019-0221-x · 2020 · External reference
Distinguishing High‐Metastasis‐Potential Circulating Tumor Cells Through Fluidic Shear Stress in a Bloodstream‐Like Microfluidic Circulatory System
10.1038/s41388-024-03075-4 · 2024 · External reference
Shear Stress Activates ATOH8 via Autocrine VEGF Promoting Glycolysis Dependent‐Survival of Colorectal Cancer Cells in the Circulation
10.1186/s13046-020-1533-0 · 2020 · External reference
Circulating Tumor Cells With Metastasis‐Initiating Competence Survive Fluid Shear Stress During Hematogenous Dissemination Through CXCR4‐PI3K/AKT Signaling
10.1016/j.canlet.2024.216870 · 2024 · External reference
Fluid Shear Stress in a Logarithmic Microfluidic Device Enhances Cancer Cell Stemness Marker Expression
10.1039/d1lc01139a · 2022 · External reference
Extracellular Vesicle‐Mediated Modulation of Stem‐Like Phenotype in Breast Cancer Cells Under Fluid Shear Stress
10.3390/biom14070757 · 2024 · External reference
Fibrinolytic Platelet Decoys Reduce Cancer Metastasis by Dissociating Circulating Tumor Cell Clusters
10.1002/adhm.202304374 · 2024 · External reference
Interactions of Platelets With Circulating Tumor Cells Contribute to Cancer Metastasis
10.1038/s41598-021-94735-y · 2021 · External reference
Contacts With Macrophages Promote an Aggressive Nanomechanical Phenotype of Circulating Tumor Cells in Prostate Cancer
10.1158/0008-5472.can-20-3595 · 2021 · External reference
TGF‐α/EGFR‐mediated Lymphatic Metastasis Reveals a Repositionable Therapeutic Target in Breast Cancer
10.1038/s41523-026-00941-0 · 2026 · External reference
Tumour Extracellular Vesicles Induce Neutrophil Extracellular Traps to Promote Lymph Node Metastasis
10.1002/jev2.12341 · 2023 · External reference
Mechanistic Study of Matrix Stiffness Promoting Lymph Node Metastasis in Cervical Cancer by Regulating NETs Formation via Piezo1
10.3390/ijms27125431 · 2026 · External reference
PIEZO1 enhances Pancreatic Cancer Neurotropism
10.1186/s12935-026-04244-z · 2026 · External reference
Stiffened Tumor Microenvironment Enhances Perineural Invasion in Breast Cancer via Integrin Signaling
10.1007/s13402-023-00901-x · 2024 · External reference
Pancreatic Cancer Fibrosis Activates Protumorigenic Schwann Cells Through a Nuclear Mechanosensing Mechanism
10.1136/gutjnl-2025-337316 · 2026 · External reference
Cervical Cancer‐Produced Neuromedin‐B Reprograms Schwann Cells to Initiate Perineural Invasion
10.1038/s41419-024-07030-9 · 2024 · External reference
Schwann Cells Induce Cancer Cell Dispersion and Invasion
10.1172/jci82658 · 2016 · External reference
Mitochondrial Glutathione Import Enables Breast Cancer Metastasis via Integrated Stress Response Signaling
10.1158/2159-8290.cd-24-1556 · 2025 · External reference
Functional Heterogeneity of MCT1 and MCT4 in Metabolic Reprogramming Affects Osteosarcoma Growth and Metastasis
10.1186/s13018-023-03623-w · 2023 · External reference
Metabolic Heterogeneity Confers Differences in Melanoma Metastatic Potential
10.1038/s41586-019-1847-2 · 2020 · External reference
Prognostic Significance of Serum Lactic Acid, Lactate Dehydrogenase, and Albumin Levels in Patients With Metastatic Colorectal Cancer
2018 · External reference
ASIC3‐Activated Key Enzymes of De Novo Lipid Synthesis Supports Lactate‐Driven EMT and the Metastasis of Colorectal Cancer Cells
10.1186/s12964-024-01762-z · 2024 · External reference
Breast Cancer Secretes Anti‐Ferroptotic MUFAs and Depends on Selenoprotein Synthesis for Metastasis
10.1038/s44321-024-00142-x · 2024 · External reference
The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
10.1158/2159-8290.cd-19-1500 · 2021 · External reference
ACSL4 and Polyunsaturated Lipids Support Metastatic Extravasation and Colonization
10.1016/j.cell.2024.10.047 · 2025 · External reference
BACH1‐induced Ferroptosis Drives Lymphatic Metastasis by Repressing the Biosynthesis of Monounsaturated Fatty Acids
10.1038/s41419-023-05571-z · 2023 · External reference
Lymph Node Environment Drives FSP1 Targetability in Metastasizing Melanoma
10.1038/s41586-025-09709-1 · 2026 · External reference
FAO‐Fueled OXPHOS and NRF2‐Mediated Stress Resilience in MICs Drive Lymph Node Metastasis
2025 · External reference
CAV2‐expressing Nerves Induce Metabolic Switch Toward Mitochondrial Oxidative Phosphorylation to Promote Cancer Stemness
10.1038/s41467-025-66914-2 · 2025 · External reference
Single‐Cell Analysis Reveals That GFAP(+) Dedifferentiated Schwann Cells Promote Tumor Progress in PNI‐Positive Distal Cholangiocarcinoma via Lactate/HMGB1 Axis
10.1038/s41419-025-07543-x · 2025 · External reference
Sensory Neurons Drive Pancreatic Cancer Progression Through Glutamatergic Neuron‐Cancer Pseudo‐Synapses
10.1016/j.ccell.2025.09.003 · 2025 · External reference
The Changing Role of Natural Killer Cells in Cancer Metastasis
10.1172/jci143762 · 2022 · External reference
Immune Checkpoints HLA‐E:CD94‐NKG2A and HLA‐C:KIR2DL1 Complementarily Shield Circulating Tumor Cells From NK‐mediated Immune Surveillance
10.1038/s41421-024-00646-3 · 2024 · External reference
Mesenchymal Stromal Cells Increase the Natural Killer Resistance of Circulating Tumor Cells via Intercellular Signaling of cGAS‐STING‐IFNβ‐HLA
10.1002/advs.202400888 · 2024 · External reference
Hybrid Epithelial‐Mesenchymal Status of Lung Cancer Dictates Metastatic Success Through Differential Interaction With NK Cells
10.1136/jitc-2023-007895 · 2024 · External reference
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