Research graph
References from Alveolar Macrophages: Development, Respiratory Homeostasis, Signal Pathways, Diseases, and Therapeutic Opportunities. Local targets link to admitted publications; unresolved targets remain external evidence.
Scavenger Receptors in Homeostasis and Immunity
10.1038/nri3515 · 2013 · External reference
The Role of Pattern‐Recognition Receptors in Innate Immunity: Update on Toll‐Like Receptors
10.1038/ni.1863 · 2010 · External reference
Innate Immunity: Current Understandings and Future Perspectives
10.1038/s41392-026-02920-0 · 2026 · External reference
Efferocytosis Signaling in the Regulation of Macrophage Inflammatory Responses
10.4049/jimmunol.1601520 · 2017 · External reference
Macrophages in Tissue Repair, Regeneration, and Fibrosis
10.1016/j.immuni.2016.02.015 · 2016 · External reference
Alveolar Macrophages Develop From Fetal Monocytes That Differentiate Into Long‐lived Cells in the First Week of Life via GM‐CSF
10.1084/jem.20131199 · 2013 · External reference
Deletion of c‐FLIP From CD11bhi Macrophages Prevents Development of Bleomycin‐induced Lung Fibrosis
10.1165/rcmb.2017-0154oc · 2018 · External reference
Reference‐Based Analysis of Lung Single‐Cell Sequencing Reveals a Transitional Profibrotic Macrophage
10.1038/s41590-018-0276-y · 2019 · External reference
Monocyte‐Derived Alveolar Macrophages Autonomously Determine Severe Outcome of Respiratory Viral Infection
10.1126/sciimmunol.abj5761 · 2022 · External reference
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
10.1016/j.immuni.2014.06.008 · 2014 · External reference
Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release
10.1002/advs.202500376 · 2026 · External reference
Alveolar Macrophage Immunometabolism and Lung Function Impairment in Smoking and Chronic Obstructive Pulmonary Disease
10.1164/rccm.201908-1683le · 2020 · External reference
Pulmonary Alveolar Proteinosis
10.1038/s41572-019-0066-3 · 2019 · External reference
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
10.1164/rccm.202203-0482oc · 2023 · External reference
Molecular Mechanisms and Emerging Therapeutics in Pulmonary Fibrosis: A Recent Update
10.1016/j.ejphar.2025.178159 · 2025 · External reference
Corticosteroid Suppression of Antiviral Immunity Increases Bacterial Loads and Mucus Production in COPD Exacerbations
10.1038/s41467-018-04574-1 · 2018 · External reference
Erratum: Emerging Therapies for Idiopathic Pulmonary Fibrosis, a Progressive Age‐Related Disease
10.1038/nrd.2017.225 · 2017 · External reference
Nanoparticle Targeting of De Novo Profibrotic Macrophages Mitigates Lung Fibrosis
10.1073/pnas.2121098119 · 2022 · External reference
Origin, Kinetics, and Characteristics of Pulmonary Macrophages in the Normal Steady State
10.1084/jem.149.6.1504 · 1979 · External reference
The Origin of Macrophages from Bone Marrow in THE Rat
1965 · External reference
Evidence for the Pulmonary Origin of Alveolar Macrophages
1982 · External reference
Cellular Chimerism of the Lung after Transplantation
10.1309/gafn-5mpa-ly8e-dtpq · 2001 · External reference
Dynamics of human Monocytes and Airway Macrophages During Healthy Aging and After Transplant
10.1084/jem.20191236 · 2020 · External reference
Long‐term Persistence of human Donor Alveolar Macrophages in Lung Transplant Recipients
10.1136/thoraxjnl-2016-208292 · 2016 · External reference
The Origin of Alveolar Macrophages in THE Transplanted Lung
10.1097/00007890-200005150-00046 · 2000 · External reference
Long‐Term Persistence of Donor Alveolar Macrophages in Human Lung Transplant Recipients That Influences Donor‐Specific Immune Responses
10.1111/ajt.13819 · 2016 · External reference
CD116+ Fetal Precursors Migrate to the Perinatal Lung and Give Rise to human Alveolar Macrophages
10.1084/jem.20210987 · 2022 · External reference
Tissue‐Resident Macrophages Originate From Yolk‐Sac‐Derived Erythro‐Myeloid Progenitors
10.1038/nature13989 · 2014 · External reference
Fate Mapping via Ms4a3‐Expression History Traces Monocyte‐Derived Cells
10.1016/j.cell.2019.08.009 · 2019 · External reference
Influenza‐Induced Monocyte‐Derived Alveolar Macrophages Confer Prolonged Antibacterial Protection
10.1038/s41590-019-0568-x · 2020 · External reference
Single Cell RNA Sequencing Identifies Unique Inflammatory Airspace Macrophage Subsets
10.1172/jci.insight.126556 · 2019 · External reference
Cell Origin Dictates Programming of Resident versus Recruited Macrophages During Acute Lung Injury
10.1165/rcmb.2017-0061oc · 2017 · External reference
A Spatially Restricted Fibrotic Niche in Pulmonary Fibrosis Is Sustained by M‐CSF/M‐CSFR Signalling in Monocyte‐Derived Alveolar Macrophages
10.1183/13993003.00646-2019 · 2020 · External reference
Monocyte‐Derived Alveolar Macrophages Drive Lung Fibrosis and Persist in the Lung Over the Life Span
10.1084/jem.20162152 · 2017 · External reference
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration Following Pneumonectomy
10.1016/j.stem.2017.03.024 · 2017 · External reference
Tissue‐Resident Macrophages Self‐Maintain Locally throughout Adult Life With Minimal Contribution From Circulating Monocytes
10.1016/j.immuni.2013.04.004 · 2013 · External reference
The Prolonged Life‐Span of Alveolar Macrophages
10.1165/rcmb.2007-0224rc · 2008 · External reference
Distinct Developmental Pathways From Blood Monocytes Generate Human Lung Macrophage Diversity
10.1016/j.immuni.2020.12.003 · 2021 · External reference
Cross‐Tissue Single‐Cell Landscape of Human Monocytes and Macrophages in Health and Disease
10.1016/j.immuni.2021.07.007 · 2021 · External reference
Host‐Viral Infection Maps Reveal Signatures of Severe COVID‐19 Patients
10.1016/j.cell.2020.05.006 · 2020 · External reference
Single‐Cell Landscape of Bronchoalveolar Immune Cells in Patients With COVID‐19
10.1038/s41591-020-0901-9 · 2020 · External reference
Discriminating Mild From Critical COVID‐19 by Innate and Adaptive Immune Single‐cell Profiling of Bronchoalveolar Lavages
10.1038/s41422-020-00455-9 · 2021 · External reference
Macrophage Regulation in Vascularization Upon Regeneration and Repair of Tissue Injury and Engineered Organ Transplantation
10.1016/j.fmre.2023.12.015 · 2025 · External reference
A Human Cell Atlas of Fetal Gene Expression
10.1126/science.aba7721 · 2020 · External reference
A Molecular Cell Atlas of the Human Lung From Single‐Cell RNA Sequencing
10.1038/s41586-020-2922-4 · 2020 · External reference
The Cytokine TGF‐β Promotes the Development and Homeostasis of Alveolar Macrophages
10.1016/j.immuni.2017.10.007 · 2017 · External reference
M1 and M2 Macrophages: Oracles of Health and Disease
10.1615/critrevimmunol.v32.i6.10 · 2012 · External reference
Single‐Cell Insights into Macrophage Subtypes in Pulmonary Infections
10.1002/advs.202510758 · 2026 · External reference
Alveolar Macrophage Metabolic Programming via a C‐Type Lectin Receptor Protects Against Lipo‐Toxicity and Cell Death
10.1038/s41467-022-34935-w · 2022 · External reference
Bacterial Pneumonia Induces Senescence in Resident Alveolar Macrophages That Are Outcompeted by Monocytes
10.1016/j.celrep.2025.115571 · 2025 · External reference
Single‐Cell Spatiotemporal Analysis of the Lungs Reveals Slamf9+ Macrophages Involved in Viral Clearance and Inflammation Resolution
10.1038/s41421-024-00734-4 · 2024 · External reference
Apolipoprotein E Controls Dectin‐1‐Dependent Development of Monocyte‐derived Alveolar Macrophages Upon Pulmonary β‐Glucan‐Induced Inflammatory Adaptation
10.1038/s41590-024-01830-z · 2024 · External reference
Lineage Tracing Reveals the Origins and Dynamics of Macrophages in Lung Injury and Repair
10.1038/s41421-025-00859-0 · 2026 · External reference
Single Cell Analysis of M. Tuberculosis Phenotype and Macrophage Lineages in the Infected Lung
10.1084/jem.20210615 · 2021 · External reference
Neonatal Imprinting of Alveolar Macrophages via Neutrophil‐Derived 12‐HETE
10.1038/s41586-022-05660-7 · 2023 · External reference
Human Rhinovirus Impairs the Innate Immune Response to Bacteria in Alveolar Macrophages in Chronic Obstructive Pulmonary Disease
10.1164/rccm.201806-1095oc · 2019 · External reference
The Lung Microenvironment Shapes a Dysfunctional Response of Alveolar Macrophages in Aging
10.1172/jci140299 · 2021 · External reference
Identification of an Increased Alveolar Macrophage Subpopulation in Old Mice That Displays Unique Inflammatory Characteristics and Is Permissive to Mycobacterium Tuberculosis Infection
10.4049/jimmunol.1900495 · 2019 · External reference
Biology of Lung Macrophages in Health and Disease
10.1016/j.immuni.2022.08.010 · 2022 · External reference
Tissue‐Resident Macrophage Ontogeny and Homeostasis
10.1016/j.immuni.2016.02.024 · 2016 · External reference
Growth of Mycobacterium Tuberculosis in Vivo Segregates With Host Macrophage Metabolism and Ontogeny
10.1084/jem.20172020 · 2018 · External reference
Innate Type 2 Lymphocytes Trigger an Inflammatory Switch in Alveolar Macrophages
10.1016/j.immuni.2025.11.015 · 2026 · External reference
Targeting Lp‐PLA2 Inhibits Profibrotic Monocyte‐Derived Macrophages in Silicosis Through Restoring Cardiolipin‐Mediated Mitophagy
10.1038/s41423-025-01288-5 · 2025 · External reference
TREM2 Promotes Lung Fibrosis via Controlling Alveolar Macrophage Survival and Pro‐Fibrotic Activity
10.1038/s41467-025-57024-0 · 2025 · External reference
Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity
10.1016/j.cell.2018.09.042 · 2018 · External reference
Parenteral BCG Vaccine Induces Lung‐Resident Memory Macrophages and Trained Immunity via the Gut‐lung Axis
10.1038/s41590-022-01354-4 · 2022 · External reference
Alveolar Macrophages Are Epigenetically Altered After Inflammation, Leading to Long‐Term Lung Immunoparalysis
10.1038/s41590-020-0673-x · 2020 · External reference
Epigenetic Reprogramming of Airway Macrophages Promotes Polarization and Inflammation in Muco‐Obstructive Lung Disease
10.1038/s41467-021-26777-9 · 2021 · External reference
Lineage‐specific Enhancers Activate Self‐Renewal Genes in Macrophages and Embryonic Stem Cells
10.1126/science.aad5510 · 2016 · External reference
A Serine/Threonine Kinase Gene Defective in Peutz‐Jeghers Syndrome
10.1038/34432 · 1998 · External reference
Macrophage Liver Kinase B1 Inhibits Foam Cell Formation and Atherosclerosis
10.1161/circresaha.117.311546 · 2017 · External reference
Critical Role of Lkb1 in the Maintenance of Alveolar Macrophage Self‐Renewal and Immune Homeostasis
10.3389/fimmu.2021.629281 · 2021 · External reference
PGE 2 Accounts for Bidirectional Changes in Alveolar Macrophage Self‐Renewal With Aging and Smoking
10.26508/lsa.202000800 · 2020 · External reference
Single Cell RNA Sequencing Unravels Mechanisms Underlying Senescence‐Like Phenotypes of Alveolar Macrophages
10.1016/j.isci.2023.107197 · 2023 · External reference
Von Hippel‐Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self‐Renewal, and Function
10.1016/j.celrep.2018.07.034 · 2018 · External reference
Alveolar Macrophages: Plasticity in a Tissue‐Specific Context
10.1038/nri3600 · 2014 · External reference
Inducible Antibacterial Responses in Macrophages
10.1038/s41577-024-01080-y · 2025 · External reference
Patrolling Alveolar Macrophages Conceal Bacteria From the Immune System to Maintain Homeostasis
10.1016/j.cell.2020.08.020 · 2020 · External reference
Information Processing During Phagocytosis
10.1038/nri3244 · 2012 · External reference
SARS‐CoV‐2 Infection Triggers Profibrotic Macrophage Responses and Lung Fibrosis
10.1016/j.cell.2021.11.033 · 2021 · External reference
Pattern Recognition Receptors
10.1016/s0092-8674(02)01201-1 · 2002 · External reference
Identification of circSlc7a11, a Novel circRNA That Functions as a Negative Regulator of Host Immune Defense Against Pulmonary Pseudomonas Aeruginosa Infection
10.1165/rcmb.2024-0295oc · 2026 · External reference
Microbiota‐Induced EI24 Improves Homeostasis but Impedes Function of Alveolar Macrophages via Metabolic Regulation
10.1038/s41467-026-69000-3 · 2026 · External reference
Circular RNA circMagi1 Regulates the Host Immune Response in Respiratory Pseudomonas Aeruginosa Infection Through G3BP2
10.1128/mbio.03617-25 · 2026 · External reference
The Pseudomonas Aeruginosa Effector Protein TesG Regulates Alternative Activation of Macrophages Through NLRC5
10.1128/msphere.00681-25 · 2025 · External reference
EGR2 is an Epigenomic Regulator of Phagocytosis and Antifungal Immunity in Alveolar Macrophages
10.1172/jci.insight.164009 · 2024 · External reference
Adiponectin Pathway Activation Dampens Inflammation and Enhances Alveolar Macrophage Fungal Killing via LC3‐Associated Phagocytosis
10.1371/journal.ppat.1012363 · 2025 · External reference
Segmented Filamentous Bacteria Reprogramming of Alveolar Macrophages Limits Postinfluenza Bacterial Pneumonia
10.1126/sciimmunol.adt8858 · 2026 · External reference
Temporo‐spatial Cellular Atlas of the Regenerating Alveolar Niche in Idiopathic Pulmonary Fibrosis
10.1038/s41467-025-61880-1 · 2025 · External reference
African Swine Fever Virus Infection Enhances CD14‐Dependent Phagocytosis of Porcine Alveolar Macrophages to Promote Bacterial Uptake and Apoptotic Body‐Mediated Viral Transmission
10.1128/jvi.00690-25 · 2025 · External reference
The Role and Phagocytic Mechanisms of Alveolar Macrophages in Inflammatory Responses Induced by Diesel Exhaust Particles
10.1021/acs.est.5c01861 · 2025 · External reference
Pro‐Resolving Lipid Mediators and Therapeutic Innovations in Resolution of Inflammation
10.1016/j.pharmthera.2024.108753 · 2025 · External reference
Resolution of Acute Inflammation in the Lung
10.1146/annurev-physiol-021113-170408 · 2014 · External reference
Mediators of the Resolution of the Inflammatory Response
10.1016/j.it.2019.01.007 · 2019 · External reference
Lipoxins: Nature's Way to Resolve Inflammation
2015 · External reference
Resolving Inflammation: Dual Anti‐inflammatory and Pro‐Resolution Lipid Mediators
10.1038/nri2294 · 2008 · External reference
Lipoxin A4 Receptor Agonist BML‐111 Induces Autophagy in Alveolar Macrophages and Protects From Acute Lung Injury by Activating MAPK Signaling
10.1186/s12931-018-0937-2 · 2018 · External reference
Resolvin D2 Regulates Type 2 Inflammatory Responses and Promotes Resolution of Mouse Allergic Inflammation
10.1111/all.15920 · 2024 · External reference
Macrophages That Have Ingested Apoptotic Cells in Vitro Inhibit Proinflammatory Cytokine Production Through Autocrine/Paracrine Mechanisms Involving TGF‐Beta, PGE2, and PAF
10.1172/jci1112 · 1998 · External reference
Immunosuppressive Effects of Apoptotic Cells
10.1038/37022 · 1997 · External reference
Continued Clearance of Apoptotic Cells Critically Depends on the Phagocyte Ucp2 Protein
10.1038/nature10340 · 2011 · External reference
Cell Type‐Specific Efferocytosis Determines Functional Plasticity of Alveolar Macrophages
10.1126/sciimmunol.adl3852 · 2025 · External reference
Bβ15‐42 Protects Against Acid‐Induced Acute Lung Injury and Secondary Pseudomonas Pneumonia in Vivo
10.1164/rccm.200904-0626oc · 2009 · External reference
Macrophage Adaptation in Airway Inflammatory Resolution
10.1183/16000617.0030-2015 · 2015 · External reference
The Micromechanics of Lung Alveoli: Structure and Function of Surfactant and Tissue Components
10.1007/s00418-018-1747-9 · 2018 · External reference
Sessile Alveolar Macrophages Communicate With Alveolar Epithelium to Modulate Immunity
10.1038/nature12902 · 2014 · External reference
Gm‐CSF Regulates Pulmonary Surfactant Homeostasis and Alveolar Macrophage‐Mediated Innate Host Defense
10.1146/annurev.physiol.64.090601.113847 · 2002 · External reference
Peroxisome Proliferator‐Activated Receptor‐γ Is Deficient in Alveolar Macrophages From Patients With Alveolar Proteinosis
10.1165/rcmb.2003-0148oc · 2003 · External reference
Alveolar Macrophages Rely on GM‐CSF From Alveolar Epithelial Type 2 Cells Before and After Birth
10.1084/jem.20210745 · 2021 · External reference
Induction of the Nuclear Receptor PPAR‐γ by the Cytokine GM‐CSF Is Critical for the Differentiation of Fetal Monocytes Into Alveolar Macrophages
10.1038/ni.3005 · 2014 · External reference
Pulmonary Alveolar Proteinosis Syndrome
10.1055/s-0039-3402727 · 2020 · External reference
C/EBPβ Regulates Lipid Metabolism and Pparg Isoform 2 Expression in Alveolar Macrophages
10.1126/sciimmunol.abj0140 · 2022 · External reference
Targeted PPARγ Deficiency in Alveolar Macrophages Disrupts Surfactant Catabolism
10.1194/jlr.m001651 · 2010 · External reference
Surfactant Protein D Inhibits Lipid‐Laden Foamy Macrophages and Lung Inflammation in Chronic Obstructive Pulmonary Disease
10.1038/s41423-022-00946-2 · 2023 · External reference
SP‐D and GM‐CSF Regulate Surfactant Homeostasis via Distinct Mechanisms
10.1152/ajplung.2001.281.3.l697 · 2001 · External reference
The Clearance of Dead Cells by Efferocytosis
10.1038/s41580-020-0232-1 · 2020 · External reference
Phagocytosis of Apoptotic Cells in Homeostasis
10.1038/ni.3253 · 2015 · External reference
Biology of the TAM Receptors
10.1101/cshperspect.a009076 · 2013 · External reference
How Macrophages Deal With Death
10.1038/s41577-019-0167-y · 2019 · External reference
Apoptotic Cell Clearance: Basic Biology and Therapeutic Potential
10.1038/nri3607 · 2014 · External reference
Pro‐Resolving Lipid Mediators Are Leads for Resolution Physiology
10.1038/nature13479 · 2014 · External reference
Macrophage Efferocytosis in Health and Disease
10.1002/cbf.3780 · 2023 · External reference
Diverse Macrophage Populations Mediate Acute Lung Inflammation and Resolution
10.1152/ajplung.00341.2013 · 2014 · External reference
Isthmin‐1 Attenuates Allergic Asthma by Stimulating Adiponectin Expression and Alveolar Macrophage Efferocytosis in Mice
10.1186/s12931-023-02569-1 · 2023 · External reference
RvD1 Improves Resident Alveolar Macrophage Self‐Renewal via the ALX/MAPK14/S100A8/A9 Pathway in Acute Respiratory Distress Syndrome
10.1016/j.jare.2024.01.017 · 2025 · External reference
Mulberroside A Inhibits NLRP6 to Prevent Alveolar Macrophage Efferocytosis and Lung‐Derived SAA3‐Platelet Transport in High Fructose‐Induced Hippocampal Inflammation
10.1016/j.phymed.2026.157903 · 2026 · External reference
Trained Immunity of Alveolar Macrophages Enhances Injury Resolution via KLF4‐MERTK‐mediated Efferocytosis
10.1084/jem.20221388 · 2023 · External reference
Monocyte‐Derived Alveolar Macrophages in ALI / ARDS: The Core Drivers of Inflammation
10.1111/imm.70125 · 2026 · External reference
Macrophage in the Crosshairs: Chemical Inhalation and Lung Immune Defense
10.1152/ajplung.00008.2026 · 2026 · External reference
Monocyte‐Macrophage Dynamics as Key in Disparate Lung and Peripheral Immune Responses in Severe Anti‐Melanoma Differentiation‐Associated Gene 5‐Positive Dermatomyositis‐Related Interstitial Lung Disease
10.1002/ctm2.70226 · 2025 · External reference
Matrix Metalloproteinases in Emphysema
10.1016/j.matbio.2018.01.018 · 2018 · External reference
Immunometabolism Governs Dendritic Cell and Macrophage Function
10.1084/jem.20151570 · 2016 · External reference
Metabolic Adaptations of Tissue‐Resident Immune Cells
10.1038/s41590-019-0407-0 · 2019 · External reference
The Development and Function of Lung‐Resident Macrophages and Dendritic Cells
10.1038/ni.3052 · 2015 · External reference
Tissue‐Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS‐Induced Inflammation
10.1165/rcmb.2019-0244oc · 2020 · External reference
Leptin Receptor Signaling Sustains Metabolic Fitness of Alveolar Macrophages to Attenuate Pulmonary Inflammation
10.1126/sciadv.abo3064 · 2022 · External reference
mTOR Regulates Metabolic Adaptation of APCs in the Lung and Controls the Outcome of Allergic Inflammation
10.1126/science.aaj2155 · 2017 · External reference
mTOR Signaling in Growth, Metabolism, and Disease
10.1016/j.cell.2017.03.035 · 2017 · External reference
Essential Role of mTORC1 in Self‐Renewal of Murine Alveolar Macrophages
10.4049/jimmunol.1501845 · 2017 · External reference
Macrophage ABCG1 Deletion Disrupts Lipid Homeostasis in Alveolar Macrophages and Moderately Influences Atherosclerotic Lesion Development in LDL Receptor‐Deficient Mice
10.1161/01.atv.0000237629.29842.4c · 2006 · External reference
S100a4+ Alveolar Macrophages Accelerate the Progression of Precancerous Atypical Adenomatous Hyperplasia by Promoting the Angiogenic Function Regulated by Fatty Acid Metabolism
10.7554/elife.101731 · 2025 · External reference
TOLLIP Inhibits Lipid Accumulation and the Integrated Stress Response in Alveolar Macrophages to Control Mycobacterium Tuberculosis Infection
10.1038/s41564-024-01641-w · 2024 · External reference
Functional and Metabolic Impairment in Cigarette Smoke‐Exposed Macrophages Is Tied to Oxidative Stress
10.1038/s41598-019-46045-7 · 2019 · External reference
Oxidative Phosphorylation Selectively Orchestrates Tissue Macrophage Homeostasis
10.1016/j.immuni.2023.01.011 · 2023 · External reference
Alveolar Macrophage Transcriptomic Profiling in COPD Shows Major Lipid Metabolism Changes
10.1183/23120541.00915-2020 · 2021 · External reference
HIF‐1α Induces Glycolytic Reprograming in Tissue‐Resident Alveolar Macrophages to Promote Cell Survival During Acute Lung Injury
10.7554/elife.77457 · 2022 · External reference
Macrophage‐Epithelial Interactions in Pulmonary Alveoli
10.1007/s00281-016-0569-x · 2016 · External reference
Accumulation of Inhibitory κB‐α as a Mechanism Contributing to the Anti‐Inflammatory Effects of Surfactant Protein‐A
10.1165/rcmb.2004-0003oc · 2004 · External reference
Interaction of Alveolar Macrophages and Airway Epithelial Cells Following Exposure to Particulate Matter Produces Mediators That Stimulate the Bone Marrow
10.1165/ajrcmb.27.1.4787 · 2002 · External reference
Interleukin‐8 Gene Expression by a Pulmonary Epithelial Cell Line. A Model for Cytokine Networks in the Lung
10.1172/jci114928 · 1990 · External reference
Alveolar Type II Epithelial Cells Produce Interleukin‐6 in Vitro and in Vivo. Regulation by Alveolar Macrophage Secretory Products
10.1172/jci117392 · 1994 · External reference
Macrophage‐Derived Oncostatin M Repairs the Lung Epithelial Barrier During Inflammatory Damage
10.1126/science.adi8828 · 2025 · External reference
Alveolar Macrophage‐Expressed Plet1 Is a Driver of Lung Epithelial Repair After Viral Pneumonia
10.1038/s41467-023-44421-6 · 2024 · External reference
Innate Immune Training Initiates Efferocytosis to Protect Against Lung Injury
10.1002/advs.202308978 · 2024 · External reference
Sbno2‐Mediated Tissue‐resident Alveolar Macrophages: A Novel Therapeutic Axis for Sepsis‐Induced Acute Lung Injury
10.1038/s41420-025-02772-7 · 2026 · External reference
Macrophage‐Derived MMP12 Promotes Fibrosis Through Sustained Damage to Endothelial Cells
10.1016/j.jhazmat.2023.132733 · 2024 · External reference
Single Nuclei RNA‐sequencing Unveils Alveolar Macrophages as Drivers of Endothelial Damage in Obese HFpEF‐related Pulmonary Hypertension
10.1186/s12933-025-02772-y · 2025 · External reference
Epithelium‐ and Endothelium‐Derived Exosomes Regulate the Alveolar Macrophages by Targeting RGS1 Mediated Calcium Signaling‐Dependent Immune Response
10.1038/s41418-021-00750-x · 2021 · External reference
Resistin Secreted by Porcine Alveolar Macrophages Leads to Endothelial Cell Dysfunction During Haemophilus Parasuis Infection
10.1080/21505594.2023.2171636 · 2023 · External reference
Exosomal miR‐218 Secreted From Endothelial Progenitor Cells Mitigates Acute Lung Injury in Sepsis Mice by Inhibiting HMGA1 in Alveolar Macrophages
10.1186/s13287-025-04558-1 · 2025 · External reference
Transplantation of Alveolar Macrophages Improves the Efficacy of Endothelial Progenitor Cell Therapy in Mouse Model of Bronchopulmonary Dysplasia
10.1152/ajplung.00274.2023 · 2024 · External reference
Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil‐Driven Inflammatory Damage
10.1016/j.cell.2019.02.028 · 2019 · External reference
Circuit Design Features of a Stable Two‐Cell System
10.1016/j.cell.2018.01.015 · 2018 · External reference
CSF1R inhibition Prevents Radiation Pulmonary Fibrosis by Depletion of Interstitial Macrophages
10.1183/13993003.02120-2017 · 2018 · External reference
Communication Between Alveolar Macrophages and Fibroblasts via the TNFSF12‐TNFRSF12A Pathway Promotes Pulmonary Fibrosis in Severe COVID‐19 Patients
10.1186/s12967-024-05381-7 · 2024 · External reference
Lung Single‐Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
10.1016/j.cell.2018.09.009 · 2018 · External reference
Perinatal Activation of the Interleukin‐33 Pathway Promotes Type 2 Immunity in the Developing Lung
10.1016/j.immuni.2016.10.031 · 2016 · External reference
Mitochondrial Pyruvate Metabolism in Club Cells Drives Airway Inflammation
10.1016/j.stemcr.2025.102742 · 2026 · External reference
The GM‐CSF Receptor Family: Mechanism of Activation and Implications for Disease
10.3109/08977194.2011.649919 · 2012 · External reference
The Granulocyte‐Macrophage Colony‐Stimulating Factor Receptor: Linking Its Structure to Cell Signaling and Its Role in Disease
10.1182/blood-2008-12-164004 · 2009 · External reference
Frontline Science: Coincidental Null Mutation of Csf2rα in a Colony of PI3Kγ−/− Mice Causes Alveolar Macrophage Deficiency and Fatal Respiratory Viral Infection
10.1189/jlb.4hi0316-157r · 2017 · External reference
Alveolar Macrophages Are Essential for Protection From Respiratory Failure and Associated Morbidity Following Influenza Virus Infection
10.1371/journal.ppat.1004053 · 2014 · External reference
GM‐CSF in Inflammation
10.1084/jem.20190945 · 2020 · External reference
Ssu72 Regulates Alveolar Macrophage Development and Allergic Airway Inflammation by Fine‐Tuning of GM‐CSF Receptor Signaling
10.1016/j.jaci.2020.07.038 · 2021 · External reference
TGF‐β Signaling by Smad Proteins
10.1016/s1359-6101(99)00025-8 · 2000 · External reference
TGFβ Signalling in Context
10.1038/nrm3434 · 2012 · External reference
Identification of Smad7, a TGFβ‐Inducible Antagonist of TGF‐β Signalling
10.1038/39369 · 1997 · External reference
Expression of TGF‐Beta 1, PDGF and IGF‐1 mRNA in Lung of Bleomycin‐A5‐Induced Pulmonary Fibrosis in Rats
1996 · External reference
Alveolar Macrophage‐Derived TGF‐β Promotes Acute Lung Injury Recovery by Regulating Inflammatory Monocyte‐Derived Macrophages
2025 · External reference
Reprogramming Alveolar Macrophage Responses to TGF‐β Reveals CCR2+ Monocyte Activity That Promotes Bronchiolitis Obliterans Syndrome
10.1172/jci159229 · 2022 · External reference
Balance Between Alveolar Macrophage IL‐6 and TGF‐Beta in Lung‐Transplant Recipients. Marseille and Montréal Lung Transplantation Group
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The Spatial and Temporal Activation of Macrophages During Fibrosis
10.1038/s41577-025-01186-x · 2025 · External reference
