Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Dynamics and Specificities of T Cells in Cancer Immunotherapy
10.1038/s41568-023-00560-y · 2023 · External reference
The Where, the When, and the How of Immune Monitoring for Cancer Immunotherapies in the Era of Checkpoint Inhibition
10.1158/1078-0432.ccr-15-1507 · 2016 · External reference
Spatially Resolved Multi‐Omics Single‐Cell Analyses Inform Mechanisms of Immune Dysfunction in Pancreatic Cancer
10.1053/j.gastro.2023.05.036 · 2023 · External reference
Nivolumab Plus Ipilimumab in Advanced Salivary Gland Cancer: A Phase 2 Trial
10.1038/s41591-023-02518-x · 2023 · External reference
Decoding the Metabolic Dialogue in the Tumor Microenvironment: From Immune Suppression to Precision Cancer Therapies
10.1186/s40164-025-00689-6 · 2025 · External reference
Understanding the Tumor Immune Microenvironment (TIME) for Effective Therapy
10.1038/s41591-018-0014-x · 2018 · External reference
Tumor‐Associated Monocytes Promote Mesenchymal Transformation Through EGFR Signaling in Glioma
10.1016/j.xcrm.2023.101177 · 2023 · External reference
A Distinct Tumor Microenvironment Makes Anaplastic Thyroid Cancer More Lethal but Immunotherapy Sensitive Than Papillary Thyroid Cancer
10.1172/jci.insight.173712 · 2024 · External reference
CD4 T Cell Dynamics Shape the Immune Response to Combination Oncolytic Herpes Virus and BRAF Inhibitor Therapy for Melanoma
10.1136/jitc-2021-004410 · 2022 · External reference
The Mathematics of Cancer: Integrating Quantitative Models
10.1038/nrc4029 · 2015 · External reference
Characterization of a Pathogenic Subpopulation of Human Glioma Associated Macrophages Linked to Glioma Progression
10.1016/j.ccell.2025.12.010 · 2026 · External reference
AP‐1: A Double‐Edged Sword in Tumorigenesis
10.1038/nrc1209 · 2003 · External reference
Isolation and Characterization of fra‐2, an Additional Member of the fos Gene Family
10.1073/pnas.87.9.3619 · 1990 · External reference
AP‐1 as a Regulator of Cell Life and Death
10.1038/ncb0502-e131 · 2002 · External reference
The Fra‐1/AP‐1 Oncoprotein: From the “Undruggable” Transcription Factor to Therapeutic Targeting
10.3390/cancers14061480 · 2022 · External reference
The Potential of Activator Protein 1 (AP‐1) in Cancer Targeted Therapy
10.3389/fimmu.2023.1224892 · 2023 · External reference
Difference in Transcriptional Regulatory Function Between c‐Fos and Fra‐2
10.1093/nar/19.20.5537 · 1991 · External reference
Transformation by Fos Proteins Requires a C‐Terminal Transactivation Domain
1993 · External reference
Fos Family Members: Regulation, Structure and Role in Oncogenic Transformation
2000 · External reference
Role of Fra‐2 in Cancer
10.1038/s41418-023-01248-4 · 2024 · External reference
Osteoclast Size Is Controlled by Fra‐2 Through LIF/LIF‐Receptor Signalling and Hypoxia
10.1038/nature07019 · 2008 · External reference
The AP1 Transcription Factor Fra2 Is Required for Efficient Cartilage Development
10.1242/dev.01414 · 2004 · External reference
Fra‐2/AP‐1 Regulates Melanoma Cell Metastasis by Downregulating Fam212b
10.1038/s41418-020-00660-4 · 2021 · External reference
Fra‐2 Is a Dominant Negative Regulator of Natural Killer Cell Development
10.3389/fimmu.2022.909270 · 2022 · External reference
Fra‐2 Regulates B Cell Development by Enhancing IRF4 and Foxo1 Transcription
10.1084/jem.20160514 · 2017 · External reference
A Validated Regulatory Network for Th17 Cell Specification
10.1016/j.cell.2012.09.016 · 2012 · External reference
Transcription Factor Fra‐2 and Its Emerging Role in Matrix Deposition, Proliferation and Inflammation in Chronic Lung Diseases
10.1016/j.cellsig.2019.109408 · 2019 · External reference
Liver Cancer Development Driven by the AP‐1/c‐Jun∼Fra‐2 Dimer Through c‐Myc
2024 · External reference
FOSL2 Promotes VEGF‐Independent Angiogenesis by Transcriptionnally Activating Wnt5a in Breast Cancer‐Associated Fibroblasts
10.7150/thno.55074 · 2021 · External reference
SOX2 Dosage Sustains Tumor‐Promoting Inflammation to Drive Disease Aggressiveness by Modulating the FOSL2/IL6 Axis
10.1186/s12943-023-01734-w · 2023 · External reference
FOSL2 Promotes Intertumoral Infiltration of T Cells and Increases Pathological Complete Response Rates in Locally Advanced Rectal Cancer Patients
10.1016/j.canlet.2023.216145 · 2023 · External reference
Alterations in Activating Protein 1 Composition Correlate With Phenotypic Differentiation Changes Induced by Resveratrol in Human Melanoma
10.1124/mol.104.006023 · 2005 · External reference
CXCL9, CXCL10, CXCL11/CXCR3 Axis for Immune Activation—A Target for Novel Cancer Therapy
10.1016/j.ctrv.2017.11.007 · 2018 · External reference
Chemokines and the Immune Response to Cancer
10.1016/j.immuni.2021.01.012 · 2021 · External reference
TGFβ Attenuates Tumour Response to PD‐L1 Blockade by Contributing to Exclusion of T Cells
10.1038/nature25501 · 2018 · External reference
Hypoxia‐/HIF‐1α‐Driven Factors of the Tumor Microenvironment Impeding Antitumor Immune Responses and Promoting Malignant Progression
10.1007/978-3-319-91287-5_27 · 2018 · External reference
Cancer Associated Fibroblasts—An Impediment to Effective Anti‐Cancer T Cell Immunity
10.3389/fimmu.2022.887380 · 2022 · External reference
Control of CD8 T‐Cell Infiltration Into Tumors by Vasculature and Microenvironment
10.1016/bs.acr.2015.05.001 · 2015 · External reference
Tumour‐Associated Vasculature in T Cell Homing and Immunity: Opportunities for Cancer Therapy
10.1038/s41577-025-01187-w · 2025 · External reference
T Cell Exclusion, Immune Privilege, and the Tumor Microenvironment
10.1126/science.aaa6204 · 2015 · External reference
Regulation of the Cell Biology of Antigen Cross‐Presentation
10.1146/annurev-immunol-041015-055523 · 2018 · External reference
Tumor Immune Evasion Through Loss of MHC Class‐I Antigen Presentation
10.1016/j.coi.2023.102329 · 2023 · External reference
Immune Evasion in Cancer: Mechanisms and Cutting‐Edge Therapeutic Approaches
10.1038/s41392-025-02280-1 · 2025 · External reference
Intratumoral Hypoxia Reduces IFN‐γ–Mediated Immunity and MHC Class I Induction in a Preclinical Tumor Model
10.4049/immunohorizons.1900017 · 2019 · External reference
Hypoxia Promotes Tumor Immune Evasion by Suppressing MHC‐I Expression and Antigen Presentation
10.1038/s44318-024-00319-7 · 2025 · External reference
Macrophage IL‐10 Blocks CD8+ T Cell‐Dependent Responses to Chemotherapy by Suppressing IL‐12 Expression in Intratumoral Dendritic Cells
10.1016/j.ccell.2014.09.006 · 2014 · External reference
Dendritic Cell Subsets in Cancer Immunity and Tumor Antigen Sensing
10.1038/s41423-023-00990-6 · 2023 · External reference
Dysfunction of Dendritic Cells in Tumor Microenvironment and Immunotherapy
10.1002/cac2.12596 · 2024 · External reference
Functional Role of Dendritic Cell Subsets in Cancer Progression and Clinical Implications
10.3390/ijms21113930 · 2020 · External reference
Metabolic Programming and Immune Suppression in the Tumor Microenvironment
10.1016/j.ccell.2023.01.009 · 2023 · External reference
T Cell Dysfunction in Cancer
10.1016/j.ccell.2018.03.012 · 2018 · External reference
Overcoming Barriers to Effective Immunotherapy: MDSCs, TAMs, and Tregs as Mediators of the Immunosuppressive Microenvironment in Head and Neck Cancer
10.1016/j.oraloncology.2016.05.002 · 2016 · External reference
Adenosine Signalling in T‐Cell Activation Favours Development of IL‐17 Positive Cells With Suppressive Properties
10.1111/imm.13608 · 2023 · External reference
CD8+ T Cell Differentiation and Dysfunction in Cancer
10.1038/s41577-021-00574-3 · 2022 · External reference
Stat5 Opposes the Transcription Factor Tox and Rewires Exhausted CD8+ T Cells Towards Durable Effector‐Like States During Chronic Antigen Exposure
10.1016/j.immuni.2023.11.005 · 2023 · External reference
Tumor‐Associated Tregs Obstruct Antitumor Immunity by Promoting T Cell Dysfunction and Restricting Clonal Diversity in Tumor‐Infiltrating CD8+ T Cells
10.1136/jitc-2022-004605 · 2022 · External reference
Tumor‐Specific T Cell Dysfunction Is a Dynamic Antigen‐Driven Differentiation Program Initiated Early During Tumorigenesis
10.1016/j.immuni.2016.07.011 · 2016 · External reference
Generation and Accumulation of Immunosuppressive Adenosine by Human CD4+CD25HighFOXP3+ Regulatory T Cells
10.1074/jbc.m109.047423 · 2010 · External reference
Therapy‐Induced Senescent Tumor Cells in Cancer Relapse
10.1016/j.jncc.2023.09.001 · 2023 · External reference
Cancer Immune Control Needs Senescence Induction by Interferon‐Dependent Cell Cycle Regulator Pathways in Tumours
10.1038/s41467-020-14987-6 · 2020 · External reference
Cancer‐Associated Fibroblasts in Cancer Drug Resistance and Cancer Progression: A Review
10.1038/s41420-025-02566-x · 2025 · External reference
Macrophages at the Interface of the Co‐Evolving Cancer Ecosystem
10.1016/j.cell.2023.02.020 · 2023 · External reference
The Complex Role of Tumor‐Infiltrating Macrophages
10.1038/s41590-022-01267-2 · 2022 · External reference
Real‐Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage‐Derived VEGFA
10.1158/2159-8290.cd-15-0012 · 2015 · External reference
Therapeutic Potential of Tumor‐Associated Neutrophils: Dual Role and Phenotypic Plasticity
10.1038/s41392-025-02242-7 · 2025 · External reference
DNASE1L3‐Expressing Dendritic Cells Promote CD8+ T Cell Function and Anti‐PD‐(L)1 Therapy Efficacy by Degrading Neutrophil Extracellular Traps
10.1016/j.ccell.2025.07.014 · 2025 · External reference
Neutrophil Extracellular Traps Promote T Cell Exhaustion in the Tumor Microenvironment
10.3389/fimmu.2021.785222 · 2021 · External reference
Decoding the Spatiotemporal Heterogeneity of Tumor‐Associated Macrophages
10.1186/s12943-024-02064-1 · 2024 · External reference
Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies
10.3389/fimmu.2021.766275 · 2021 · External reference
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer
10.1158/2159-8290.cd-23-1380 · 2024 · External reference
Decoding Metastatic Microenvironments Through Single‐Cell Omics Reveals New Insights Into Niche Dynamics and Tumor Evolution
10.1371/journal.pbio.3003299 · 2025 · External reference
Spatial Architecture of the Immune Microenvironment Orchestrates Tumor Immunity and Therapeutic Response
10.1186/s13045-021-01103-4 · 2021 · External reference
Spatial Dissection of Tumour Microenvironments in Gastric Cancers Reveals the Immunosuppressive Crosstalk Between CCL2+ Fibroblasts and STAT3‐Activated Macrophages
10.1136/gutjnl-2024-332901 · 2025 · External reference
Spatially Organized Multicellular Immune Hubs in Human Colorectal Cancer
10.1016/j.cell.2021.08.003 · 2021 · External reference
Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma
10.1136/jitc-2024-011380 · 2025 · External reference
Updates on the Hematologic Tumor Microenvironment and Its Therapeutic Targeting
10.3324/haematol.2018.195396 · 2019 · External reference
Dynamic Responses of the Haematopoietic Stem Cell Niche to Diverse Stresses
10.1038/s41556-019-0444-9 · 2020 · External reference
Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
10.1158/2159-8290.cd-22-0196 · 2022 · External reference
Durotaxis Is a Driver and Potential Therapeutic Target in Lung Fibrosis and Metastatic Pancreatic Cancer
10.1038/s41556-025-01697-8 · 2025 · External reference
Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML
10.1016/j.stem.2017.11.006 · 2018 · External reference
Stromal and Immune Cell Dynamics in Tumor Associated Tertiary Lymphoid Structures and Anti‐Tumor Immune Responses
10.3389/fcell.2022.933113 · 2022 · External reference
Metabolic Crossroads: Unravelling Immune Cell Dynamics in Gastrointestinal Cancer Drug Resistance
2025 · External reference
Immune Cell and Tumor Cell‐Derived CXCL10 Is Indicative of Immunotherapy Response in Metastatic Melanoma
10.1136/jitc-2021-003521 · 2021 · External reference
CXCR3 Expression in Regulatory T Cells Drives Interactions With Type I Dendritic Cells in Tumors to Restrict CD8+ T Cell Antitumor Immunity
10.1016/j.immuni.2023.06.003 · 2023 · External reference
Overexpression and Immunosuppressive Functions of Transforming Growth Factor 1, Vascular Endothelial Growth Factor and Interleukin‐10 in Epithelial Ovarian Cancer
2012 · External reference
A Balance Score Between Immune Stimulatory and Suppressive Microenvironments Identifies Mediators of Tumour Immunity and Predicts Pan‐Cancer Survival
10.1038/s41416-020-01145-4 · 2021 · External reference
Research Progress of HIF‐1a on Immunotherapy Outcomes in Immune Vascular Microenvironment
10.3389/fimmu.2025.1549276 · 2025 · External reference
CD73 Immune Checkpoint Defines Regulatory NK Cells Within the Tumor Microenvironment
10.1172/jci128895 · 2020 · External reference
Hypoxia Induces HIF1α‐Dependent Epigenetic Vulnerability in Triple Negative Breast Cancer to Confer Immune Effector Dysfunction and Resistance to Anti‐PD‐1 Immunotherapy
10.1038/s41467-022-31764-9 · 2022 · External reference
The Role of Hypoxia‐Inducible Factor 1 in Tumor Immune Evasion
10.1002/med.21771 · 2021 · External reference
Ferroptosis: Principles and Significance in Health and Disease
10.1186/s13045-024-01564-3 · 2024 · External reference
Hypoxia‐Inducible Factors: A Central Link Between Inflammation and Cancer
10.1172/jci84430 · 2016 · External reference
10.48101/ujms.v126.10710
10.48101/ujms.v126.10710 · External reference
CAFs Vs. TECs: When Blood Feuds Fuel Cancer Progression, Dissemination and Therapeutic Resistance
2024 · External reference
Cellular and Extracellular Components in Tumor Microenvironment and Their Application in Early Diagnosis of Cancers
2020 · External reference
Classifying the Linkage Between Adipose Tissue Inflammation and Tumor Growth Through Cancer‐Associated Adipocytes
2020 · External reference
Role of Hypoxia in Inhibiting Dendritic Cells by VEGF Signaling in Tumor Microenvironments: Mechanism and Application
2021 · External reference
Multiplexed Imaging Mass Cytometry Analysis Characterizes the Vascular Niche in Pancreatic Cancer
10.1158/0008-5472.can-23-2352 · 2024 · External reference
Single‐Cell Atlas of Endothelial and Mural Cells Across Primary and Metastatic Brain Tumors
10.1016/j.immuni.2025.02.022 · 2025 · External reference
HIF‐2α Inhibition Disrupts Leukemia Stem Cell Metabolism and Impairs Vascular Microenvironment to Enhance Chronic Myeloid Leukemia Treatment
10.1016/j.canlet.2024.217060 · 2024 · External reference
Treatment‐Induced Arteriolar Revascularization and miR‐126 Enhancement in Bone Marrow Niche Protect Leukemic Stem Cells in AML
10.1186/s13045-021-01133-y · 2021 · External reference
Overcoming Cancer Treatment Resistance: Unraveling the Role of Cancer‐Associated Fibroblasts
10.1016/j.jncc.2025.03.002 · 2025 · External reference
Augmenting Antitumor Immune Responses With Epigenetic Modifying Agents
2015 · External reference
Epigenetics: Mechanisms, Potential Roles, and Therapeutic Strategies in Cancer Progression
10.1016/j.gendis.2023.04.040 · 2024 · External reference
Therapy‐Induced Cellular Senescence: Potentiating Tumor Elimination or Driving Cancer Resistance and Recurrence?
10.3390/cells13151281 · 2024 · External reference
Combining Epigenetic and Immune Therapy to Combat Cancer
10.1158/0008-5472.can-15-2125 · 2016 · External reference
The Emerging Role of Epigenetic Therapeutics in Immuno‐Oncology
10.1038/s41571-019-0266-5 · 2020 · External reference
Impact of Oncogenic Pathways on Evasion of Antitumour Immune Responses
10.1038/nrc.2017.117 · 2018 · External reference
Targeting Oncogenic Signal Pathway to Improve Cancer Immunotherapy: Insights and Perspectives
10.1016/j.bcp.2025.117043 · 2025 · External reference
WNT/β‐Catenin Pathway Activation Correlates With Immune Exclusion Across Human Cancers
10.1158/1078-0432.ccr-18-1942 · 2019 · External reference
Identification of a PTEN‐Regulated STAT3 Brain Tumor Suppressor Pathway
10.1101/gad.1606508 · 2008 · External reference
Bridging Innate and Adaptive Tumor Immunity: CGAS–STING Pathway Activation to Potentiate Immune Checkpoint Blockade
2025 · External reference
The cGAS‒STING Pathway in Cancer Immunity: Mechanisms, Challenges, and Therapeutic Implications
10.1186/s13045-025-01691-5 · 2025 · External reference
Spatial Tumor Immune Heterogeneity Facilitates Subtype Co‐Existence and Therapy Response in Pancreatic Cancer
10.1038/s41467-024-55330-7 · 2025 · External reference
Gut Microbial Metabolites in Cancer Immunomodulation
10.1186/s12943-025-02521-5 · 2025 · External reference
Microbiota Boost Immunotherapy? A Meta‐Analysis Dives Into Fecal Microbiota Transplantation and Immune Checkpoint Inhibitors
2025 · External reference
Microbiota‐Driven Antitumour Immunity Mediated by Dendritic Cell Migration
10.1038/s41586-025-09249-8 · 2025 · External reference
Microbiome Alteration via Fecal Microbiota Transplantation Is Effective for Refractory Immune Checkpoint Inhibitor–Induced Colitis
10.1126/scitranslmed.abq4006 · 2023 · External reference
Microbiome Modulation of Tumorigenesis and Immune Responses
10.1186/s12929-025-01208-9 · 2026 · External reference
Gut Dysbiosis in Oncology: A Risk Factor for Immunoresistance
10.1038/s41422-025-01212-6 · 2026 · External reference
A Consensus Statement on Establishing Causality, Therapeutic Applications and the Use of Preclinical Models in Microbiome Research
10.1038/s41575-025-01041-3 · 2025 · External reference
Cigarette Smoke Extract Induced Cytokine and Chemokine Gene Expression Changes in COPD Macrophages
10.1016/j.cyto.2008.02.001 · 2008 · External reference
Gene‐Expression Profiles in Gastric Epithelial Cells Stimulated With Spiral and Coccoid Helicobacter pylori
10.1099/jmm.0.46456-0 · 2006 · External reference
Helicobacter pylori Infection
10.1038/s41572-023-00431-8 · 2023 · External reference
Chromatin Accessibility Uncovers KRAS‐Driven FOSL2 Promoting Pancreatic Ductal Adenocarcinoma Progression Through Up‐Regulation of CCL28
10.1038/s41416-023-02313-y · 2023 · External reference
LncRNA ITGB2‐AS1 Promotes Cisplatin Resistance of Non‐Small Cell Lung Cancer by Inhibiting Ferroptosis via Activating the FOSL2/NAMPT Axis
10.1080/15384047.2023.2223377 · 2023 · External reference
LncRNA GUARDIN Suppresses Cellular Senescence Through a LRP130‐PGC1α‐FOXO4‐p21‐Dependent Signaling Axis
2020 · External reference
Integration of ATAC‐Seq and RNA‐Seq Reveals FOSL2 Drives Human Liver Progenitor‐Like Cell Aging by Regulating Inflammatory Factors
2023 · External reference
Hormonal Modulation of Major Histocompatibility Complex Class I Gene Expression Involves an Enhancer A‐Binding Complex Consisting of Fra‐2 and the p50 Subunit of NF‐Kappa B
10.1074/jbc.270.19.11453 · 1995 · External reference
Immune Correlates and Mechanisms of TIL Therapy Efficacy: Current Insights and Knowledge Gaps
10.1016/j.trecan.2025.08.002 · 2025 · External reference
Decoding and Overcoming T Cell Exhaustion: Epigenetic and Transcriptional Dynamics in CAR‐T Cells Against Solid Tumors
10.1016/j.ymthe.2024.04.004 · 2024 · External reference
Pan‐Cancer T Cell Atlas Links a Cellular Stress Response State to Immunotherapy Resistance
10.1038/s41591-023-02371-y · 2023 · External reference
Regulatory T Cells: Barriers of Immune Infiltration Into the Tumor Microenvironment
10.3389/fimmu.2021.702726 · 2021 · External reference
Regulatory T Cells in Tumor Microenvironment and Approach for Anticancer Immunotherapy
10.4110/in.2020.20.e4 · 2020 · External reference
Immunotherapy of Cancer by Targeting Regulatory T Cells
10.1016/j.intimp.2021.108469 · 2022 · External reference
Immunomodulation of T Helper Cells by Tumor Microenvironment in Oral Cancer Is Associated With CCR8 Expression and Rapid Membrane Vitamin D Signaling Pathway
10.3389/fimmu.2021.643298 · 2021 · External reference
Deciphering Regulatory T‐Cell Dynamics in Cancer Immunotherapy: Mechanisms, Implications, and Therapeutic Innovations
10.1021/acsptsci.4c00156 · 2024 · External reference
IL‐4/CCL22/CCR4 Axis Controls Regulatory T‐Cell Migration That Suppresses Inflammatory Bone Loss in Murine Experimental Periodontitis
10.1002/jbmr.2376 · 2015 · External reference
Specific Recruitment of Regulatory T Cells in Ovarian Carcinoma Fosters Immune Privilege and Predicts Reduced Survival
10.1038/nm1093 · 2004 · External reference
Dynamic CD8+ T Cell Responses to Cancer Immunotherapy in Human Regional Lymph Nodes Are Disrupted in Metastatic Lymph Nodes
10.1016/j.cell.2023.02.021 · 2023 · External reference
CCL17 and CCL22 Induce CCR4 Receptor Expression and Promote Cytokine‐Induced Killer Cells Migration
10.1097/cad.0000000000001256 · 2022 · External reference
CCR8+FOXp3+ Treg Cells as Master Drivers of Immune Regulation
10.1073/pnas.1621280114 · 2017 · External reference
Disruption of the CCL1‐CCR8 Axis Inhibits Vascular Treg Recruitment and Function and Promotes Atherosclerosis in Mice
10.1016/j.yjmcc.2019.05.009 · 2019 · External reference
Tumour Hypoxia Promotes Tolerance and Angiogenesis via CCL28 and Treg Cells
10.1038/nature10169 · 2011 · External reference
CXCL9/10‐Engineered Dendritic Cells Promote T Cell Activation and Enhance Immune Checkpoint Blockade for Lung Cancer
10.1016/j.xcrm.2024.101479 · 2024 · External reference
CXCL9 Secreted by Tumor‐Associated Dendritic Cells Up‐Regulates PD‐L1 Expression in Bladder Cancer Cells by Activating the CXCR3 Signaling
2021 · External reference
Regulatory T Cells Control Endothelial Chemokine Production and Migration of T Cells Into Intestinal Tumors of APCmin/+ Mice
10.1007/s00262-018-2161-9 · 2018 · External reference
Real‐Time Imaging of Resident T Cells in Human Lung and Ovarian Carcinomas Reveals How Different Tumor Microenvironments Control T Lymphocyte Migration
10.3389/fimmu.2015.00500 · 2015 · External reference
S1PR1 is Crucial for Accumulation of Regulatory T Cells in Tumors via STAT3
10.1016/j.celrep.2014.02.016 · 2014 · External reference
High Endothelial Venules as Potential Gateways for Therapeutics
10.1016/j.it.2022.07.002 · 2022 · External reference
VEGFA‐VEGFR Pathway Blockade Inhibits Tumor‐Induced Regulatory T‐Cell Proliferation in Colorectal Cancer
10.1158/0008-5472.can-12-2325 · 2013 · External reference
The Contribution of Vascular Endothelial Growth Factor to the Induction of Regulatory T‐Cells in Malignant Effusions
2009 · External reference
Targeting VEGFR2 With Ramucirumab Strongly Impacts Effector/Activated Regulatory T Cells and CD8+ T Cells in the Tumor Microenvironment
10.1186/s40425-018-0403-1 · 2018 · External reference
Efficient Treg Depletion Induces T‐Cell Infiltration and Rejection of Large Tumors
10.1002/eji.201041093 · 2010 · External reference
Exploring the Effect of Canine Cancer‐Associated Fibroblasts on T Cell Dynamics Through the CXCL12/CXCR4 Axis Modulated by TGF‐β1
10.1038/s41598-025-16312-x · 2025 · External reference
Cancer Associated Fibroblasts in Cancer Development and Therapy
10.1186/s13045-025-01688-0 · 2025 · External reference
Regulatory T Cells Promote Cancer Immune‐Escape Through Integrin αvβ8‐Mediated TGF‐β Activation
10.1038/s41467-021-26352-2 · 2021 · External reference
Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation During the Primary Response to Vaccination
2016 · External reference
Infiltration of CD8+ T Cells Into Tumor Cell Clusters in Triple‐Negative Breast Cancer
10.1073/pnas.1817652116 · 2019 · External reference
Stromal Cell Diversity Associated With Immune Evasion in Human Triple‐Negative Breast Cancer
2020 · External reference
Tumor‐Derived Myeloid Cell Chemoattractants and T Cell Exclusion in Pancreatic Cancer
10.3389/fimmu.2020.605619 · 2020 · External reference
Tertiary Lymphoid Structures in Cancer
10.1126/science.abf9419 · 2022 · External reference
Tumor‐Draining Lymph Nodes Are Survival Niches That Support T Cell Priming Against Lymphatic Transported Tumor Antigen and Effects of Immune Checkpoint Blockade in TNBC
10.1007/s00262-020-02792-5 · 2021 · External reference
Immune Mechanisms Orchestrate Tertiary Lymphoid Structures in Tumors via Cancer‐Associated Fibroblasts
10.1016/j.celrep.2021.109422 · 2021 · External reference
Functional Th1‐Oriented T Follicular Helper Cells That Infiltrate Human Breast Cancer Promote Effective Adaptive Immunity
10.1172/jci139905 · 2021 · External reference
T Follicular Helper Cells in Cancer
10.1016/j.trecan.2022.12.007 · 2023 · External reference
T Follicular Helper and B Cell Crosstalk in Tertiary Lymphoid Structures and Cancer Immunotherapy
10.1038/s41467-022-29753-z · 2022 · External reference
Immune Evasion Mechanisms in Early‐Stage I High‐Grade Serous Ovarian Carcinoma: Insights Into Regulatory T Cell Dynamics
10.1038/s41419-025-07557-5 · 2025 · External reference
Expansion of Tumor‐Associated Treg Cells Upon Disruption of a CTLA‐4‐Dependent Feedback Loop
10.1016/j.cell.2021.05.027 · 2021 · External reference
Unravelling the Heterogeneity and Dynamic Relationships of Tumor‐Infiltrating T Cells by Single‐Cell RNA Sequencing Analysis
10.1002/jlb.6mr0320-234r · 2020 · External reference
T Cell Dynamics With Neoadjuvant Immunotherapy in Head and Neck Cancer
10.1038/s41571-024-00969-w · 2025 · External reference
Divergent Clonal Differentiation Trajectories of T Cell Exhaustion
10.1038/s41590-022-01337-5 · 2022 · External reference
TIM‐3+ CD8 T Cells With a Terminally Exhausted Phenotype Retain Functional Capacity in Hematological Malignancies
10.1126/sciimmunol.adg1094 · 2024 · External reference
CD8+ T Cell States in Human Cancer: Insights From Single‐Cell Analysis
10.1038/s41568-019-0235-4 · 2020 · External reference
Early Precursor T Cells Establish and Propagate T Cell Exhaustion in Chronic Infection
10.1038/s41590-020-0760-z · 2020 · External reference
TOX Is a Critical Regulator of Tumour‐Specific T Cell Differentiation
10.1038/s41586-019-1324-y · 2019 · External reference
Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy
10.1016/j.cell.2019.10.029 · 2019 · External reference
Differential Regulation of Transcription Factor T‐Bet Induction During NK Cell Development and T Helper‐1 Cell Differentiation
10.1016/j.immuni.2022.03.005 · 2022 · External reference
T‐Helper‐1‐Cell Cytokines Drive Cancer Into Senescence
10.1038/nature11824 · 2013 · External reference
Genome‐Wide Analyses Reveal the IRE1a‐XBP1 Pathway Promotes T Helper Cell Differentiation by Resolving Secretory Stress and Accelerating Proliferation
10.1186/s13073-018-0589-3 · 2018 · External reference
CD4+ T Helper 2 Cells Suppress Breast Cancer by Inducing Terminal Differentiation
10.1084/jem.20201963 · 2022 · External reference
Unlocking the Complexities of Tumor‐Associated Regulatory T Cells
2018 · External reference
Sequential Induction of Effector Function, Tissue Migration and Cell Death During Polyclonal Activation of Mouse Regulatory T‐Cells
10.1371/journal.pone.0050080 · 2012 · External reference
PD‐L1–PD‐1 Interactions Limit Effector Regulatory T Cell Populations at Homeostasis and During Infection
10.1038/s41590-022-01170-w · 2022 · External reference
A Multi‐Omics Analysis of Effector and Resting Treg Cells in Pan‐Cancer
10.1016/j.compbiomed.2025.110021 · 2025 · External reference
Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic‐Derived From Peripherally Induced Foxp3+ T Regulatory Cells
2010 · External reference
Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor‐Infiltrating T Regulatory Cells
10.1016/j.immuni.2016.10.021 · 2016 · External reference
Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single‐Cell Sequencing
10.1016/j.cell.2017.05.035 · 2017 · External reference
CD74 Supports Accumulation and Function of Regulatory T Cells in Tumors
10.1038/s41467-024-47981-3 · 2024 · External reference
Dynamic Foxp3‐Chromatin Interaction Controls Tunable Treg Cell Function
10.1084/jem.20232068 · 2024 · External reference
Immune Suppression by Human Thymus‐Derived Effector Tregs Relies on Glucose/Lactate‐Fueled Fatty Acid Synthesis
10.1016/j.celrep.2024.114681 · 2024 · External reference
Fragile Treg Cells: Traitors in Immune Homeostasis?
10.1016/j.phrs.2024.107297 · 2024 · External reference
Anti‐PD‐1 Amplifies Costimulation in Melanoma‐Infiltrating Th1‐Like Foxp3+ Regulatory T Cells to Alleviate Local Immunosuppression
10.1136/jitc-2024-009435 · 2025 · External reference
CD8+ T Cell Exhaustion in the Tumor Microenvironment of Breast Cancer
10.3389/fimmu.2024.1507283 · 2024 · External reference
Functional Tumor‐Reactive CD8 + T Cells in Pancreatic Cancer
10.1186/s13046-025-03517-1 · 2025 · External reference
Hierarchical Transcriptional Network Governing Heterogeneous T Cell Exhaustion and Its Implications for Immune Checkpoint Blockade
10.3389/fimmu.2023.1198551 · 2023 · External reference
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
10.1016/j.immuni.2020.04.014 · 2020 · External reference
Cellular and Molecular Waypoints Along the Path of T Cell Exhaustion
10.1126/sciimmunol.adg3868 · 2023 · External reference
Longitudinal Immune Profiling Reveals Unique Myeloid and T‐Cell Phenotypes Associated With Spontaneous Immunoediting in a Prostate Tumor Model
10.1158/2326-6066.cir-20-0637 · 2021 · External reference
Tissue Adaptation of CD4 T Lymphocytes in Homeostasis and Cancer
10.3389/fimmu.2024.1379376 · 2024 · External reference
Tumor Glucose Metabolism and the T Cell Glycocalyx: Implication for T Cell Function
10.3389/fimmu.2024.1409238 · 2024 · External reference
De Novo Epigenetic Programs Inhibit Pd‐1 Blockade‐Mediated T‐Cell Rejuvenation
10.1016/j.cell.2017.06.007 · 2017 · External reference
The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation
2018 · External reference
TET2 Regulates Early and Late Transitions in Exhausted CD8+ T Cell Differentiation and Limits CAR T Cell Function
10.1126/sciadv.adp9371 · External reference
Epigenetic Scarring of Exhausted T Cells Hinders Memory Differentiation Upon Eliminating Chronic Antigenic Stimulation
10.1038/s41590-021-00975-5 · 2021 · External reference
Epigenetic Scars of CD8+ T Cell Exhaustion Persist After Cure of Chronic Infection in Humans
10.1038/s41590-021-00979-1 · 2021 · External reference
Trans‐Endocytosis of CD80 and CD86: A Molecular Basis for the Cell Extrinsic Function of CTLA‐4
10.1126/science.1202947 · 2011 · External reference
Treg‐Expressed CTLA‐4 Depletes CD80/CD86 by Trogocytosis, Releasing Free PD‐L1 on Antigen‐Presenting Cells
10.1073/pnas.2023739118 · 2021 · External reference
Treg and CTLA‐4: Two Intertwining Pathways to Immune Tolerance
10.1016/j.jaut.2013.06.006 · 2013 · External reference
CD25‐Treg‐Depleting Antibodies Preserving IL‐2 Signaling on Effector T Cells Enhance Effector Activation and Antitumor Immunity
10.1038/s43018-020-00133-0 · 2020 · External reference
Metabolic Pathways Involved in Regulatory T Cell Functionality
10.3389/fimmu.2019.02839 · 2019 · External reference
Metabolic Regulation of Regulatory T Cells: Mechanisms, Heterogeneity, and Implications in Disease
10.3389/fimmu.2025.1729690 · 2025 · External reference
Systematic Elucidation and Pharmacological Targeting of Tumor‐Infiltrating Regulatory T Cell Master Regulators
10.1016/j.ccell.2023.04.003 · 2023 · External reference
A Systematic Comparison of FOSL1, FOSL2 and BATF‐Mediated Transcriptional Regulation During Early Human Th17 Differentiation
10.1093/nar/gkac256 · 2022 · External reference
Genome‐Wide Analysis of STAT3‐Mediated Transcription During Early Human Th17 Cell Differentiation
10.1016/j.celrep.2017.05.013 · 2017 · External reference
Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells
10.1021/acsomega.1c03681 · 2021 · External reference
PSGL‐1 Is an Immune Checkpoint Regulator That Promotes T Cell Exhaustion
10.1016/j.immuni.2016.04.015 · 2016 · External reference
Long‐Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA‐155
10.1016/j.celrep.2018.04.038 · 2018 · External reference
The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development
10.1016/j.celrep.2020.107826 · 2020 · External reference
CTLA‐4‐Mediated Posttranslational Modifications Direct Cytotoxic T‐Lymphocyte Differentiation
10.1038/cdd.2017.102 · 2017 · External reference
Adenosine Promotes Foxp3 Expression in Treg Cells in Sepsis Model by Activating JNK/AP‐1 Pathway
2016 · External reference
Integrative Epigenetic Analysis Reveals AP‐1 Promotes Activation of Tumor‐Infiltrating Regulatory T Cells in HCC
10.1007/s00018-023-04746-3 · 2023 · External reference
JunB Promotes Th17 Cell Identity and Restrains Alternative CD4+ T‐Cell Programs During Inflammation
10.1038/s41467-017-00380-3 · 2017 · External reference
Genome‐Wide Identification of Novel Genes Involved in Early Th1 and Th2 Cell Differentiation
10.4049/jimmunol.178.6.3648 · 2007 · External reference
Balance Between Immunoregulatory B Cells and Plasma Cells Drives Pancreatic Tumor Immunity
10.1016/j.xcrm.2022.100744 · 2022 · External reference
B Cells in the Tumor Microenvironment: Multi‐Faceted Organizers, Regulators, and Effectors of Anti‐Tumor Immunity
10.1016/j.ccell.2023.02.017 · 2023 · External reference
A Blueprint for Tumor‐Infiltrating B Cells Across Human Cancers
10.1126/science.adj4857 · 2024 · External reference
Mature Tertiary Lymphoid Structures Predict Immune Checkpoint Inhibitor Efficacy in Solid Tumors Independently of PD‐L1 Expression
10.1038/s43018-021-00232-6 · 2021 · External reference
Tertiary Lymphoid Structures and B Cells Determine Clinically Relevant T Cell Phenotypes in Ovarian Cancer
10.1038/s41467-024-46873-w · 2024 · External reference
Dynamic Roles of Tumor‐Infiltrating B Lymphocytes in Cancer Immunotherapy
10.1007/s00262-024-03936-7 · 2025 · External reference
Cross‐Talk Between Myeloid and B Cells Shapes the Distinct Microenvironments of Primary and Secondary Liver Cancer
10.1158/0008-5472.can-23-0193 · 2023 · External reference
Tumour‐Infiltrating B Cells: Immunological Mechanisms, Clinical Impact and Therapeutic Opportunities
10.1038/s41568-022-00466-1 · 2022 · External reference
Defining HPV‐Specific B Cell Responses in Patients With Head and Neck Cancer
10.1038/s41586-020-2931-3 · 2021 · External reference
Tumor‐Reactive Antibodies Evolve From Non‐Binding and Autoreactive Precursors
10.1016/j.cell.2022.02.012 · 2022 · External reference
Chemotherapy Markedly Reduces B Cells but Not T Cells and NK Cells in Patients With Cancer
10.1007/s00262-019-02449-y · 2020 · External reference
Breaching B Cell Tolerance in the Tumor Microenvironment
10.1016/j.ccell.2022.03.011 · 2022 · External reference
Germinal Center‐Dependent and ‐Independent Immune Responses of Tumor‐Infiltrating B Cells in Human Cancers
10.1038/s41423-023-01060-7 · 2023 · External reference
B Cell Trajectories Influence Cancer Outcomes
10.1126/science.adp1865 · 2024 · External reference
Single‐Cell Landscape and Clinical Outcomes of Infiltrating B Cells in Colorectal Cancer
10.1111/imm.13568 · 2023 · External reference
B Cells, Plasma Cells and Antibody Repertoires in the Tumour Microenvironment
10.1038/s41577-019-0257-x · 2020 · External reference
Granzyme B‐Producing B Cells: A Bidirectional Relationship With Breast Cancer Cells and Implications for Immunotherapy
10.62347/ansn3150 · 2025 · External reference
Adenosine‐Producing Regulatory B Cells in Head and Neck Cancer
10.1007/s00262-020-02535-6 · 2020 · External reference
A Novel MDSC‐Induced PD‐1‐PD‐L1+ B‐Cell Subset in Breast Tumor Microenvironment Possesses Immuno‐Suppressive Properties
10.1080/2162402x.2017.1413520 · 2018 · External reference
Selective Genomic Targeting by FRA‐2/FOSL2 Transcription Factor: Regulation of the Rgs4 Gene Is Mediated by a Variant Activator Protein 1 (AP‐1) Promoter Sequence/CREB‐Binding Protein (CBP) Mechanism
2011 · External reference
FOS+ B Cells: Key Mediators of Immunotherapy Resistance in Diverse Cancer Types
10.1016/j.omton.2024.200895 · 2024 · External reference
Tumor Immunoevasion by the Conversion of Effector NK Cells Into Type 1 Innate Lymphoid Cells
10.1038/ni.3800 · 2017 · External reference
Natural Killer Cells Infiltrating human Nonsmall‐Cell Lung Cancer Are Enriched in CD56 Bright CD16(‐) Cells and Display an Impaired Capability to Kill Tumor Cells
10.1002/cncr.23239 · 2008 · External reference
Natural Killer Cell Accumulation in Tumors Is Dependent on IFN‐Gamma and CXCR3 Ligands
10.1158/0008-5472.can-08-1440 · 2008 · External reference
CXCL10‐Induced Migration of Adoptively Transferred Human Natural Killer Cells Toward Solid Tumors Causes Regression of Tumor Growth In Vivo
10.1007/s00262-014-1629-5 · 2015 · External reference
C3aR Signaling Inhibits NK‐Cell Infiltration Into the Tumor Microenvironment in Mouse Models
10.1158/2326-6066.cir-21-0435 · 2022 · External reference
NK Cells Stimulate Recruitment of cDC1 Into the Tumor Microenvironment Promoting Cancer Immune Control
10.1016/j.cell.2018.01.004 · 2018 · External reference
Distribution of DC Subtypes: CD83+, DC‐LAMP+, CD1a+, CD1c+, CD123+, and DC‐SIGN+ in the Tumor Microenvironment of Endometrial Cancers‐Correlation With Clinicopathologic Features
10.3390/ijms24031933 · 2023 · External reference
Dysregulation of DNAM‐1‐Mediated NK Cell Anti‐Cancer Responses in the Tumor Microenvironment
10.3390/cancers15184616 · 2023 · External reference
Bladder Tumor ILC1s Undergo Th17‐Like Differentiation in Human Bladder Cancer
10.1002/cam4.4243 · 2021 · External reference
Targeting Lactylation Reinforces NK Cell Cytotoxicity Within the Tumor Microenvironment
10.1038/s41590-025-02178-8 · 2025 · External reference
Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells
10.1158/2159-8290.cd-23-0334 · 2024 · External reference
CD73 Promotes the Maturation of Murine NK Cells and Their Survival in the Tumor Microenvironment
10.1093/jleuko/qiaf011 · 2025 · External reference
Landscape of Innate Lymphoid Cells in Human Head and Neck Cancer Reveals Divergent NK Cell States in the Tumor Microenvironment
10.1073/pnas.2101169118 · 2021 · External reference
Interleukin‐35 Impairs Human NK Cell Effector Functions and Induces Their ILC1‐Like Conversion With Tissue Residency Features
10.1038/s41467-025-61196-0 · 2025 · External reference
TCR‐Engineered iNKT Cells Induce Robust Antitumor Response by Dual Targeting Cancer and Suppressive Myeloid Cells
10.1126/sciimmunol.abn6563 · 2022 · External reference
Charting a Killer Course to the Solid Tumor: Strategies to Recruit and Activate NK Cells in the Tumor Microenvironment
10.3389/fimmu.2023.1286750 · 2023 · External reference
TRAIL Expression by Activated Human CD4(+)V Alpha 24NKT Cells Induces In Vitro and In Vivo Apoptosis of Human Acute Myeloid Leukemia Cells
10.1182/blood.v97.7.2067 · 2001 · External reference
Innate Lymphocytes: Pathogenesis and Therapeutic Targets of Liver Diseases and Cancer
10.1038/s41423-020-00561-z · 2021 · External reference
Anti‐Vα24Jα18 TCR Antibody Tunes iNKT Cell Responses to Target and Kill CD1d‐Negative Tumors in an FcγRII (CD32)‐Dependent Manner
10.1158/2767-9764.crc-23-0203 · 2024 · External reference
Vorinostat Restores iNKT Cell Functionality in Aggressive Cholangiocarcinoma
10.1016/j.biopha.2025.117964 · 2025 · External reference
CD1d Induction in Solid Tumor Cells by Histone Deacetylase Inhibitors Through Inhibition of HDAC1/2 and Activation of Sp1
10.4161/epi.19373 · 2012 · External reference
Vam6 Reduces iNKT Cell Function in Tumor via Modulating AMPK/mTOR Pathways
10.3389/fimmu.2022.1051045 · 2022 · External reference
Antigen Priming Induces Functional Reprogramming in iNKT Cells via Metabolic and Epigenetic Regulation: An Insight Into iNKT Cell‐Based Antitumor Immunotherapy
10.1158/2326-6066.cir-23-0448 · 2023 · External reference
Regulation of the Terminal Maturation of iNKT Cells by Mediator Complex Subunit 23
10.1038/s41467-018-06372-1 · 2018 · External reference
iNKT Cells Orchestrate a Switch From Inflammation to Resolution of Sterile Liver Injury
10.1016/j.immuni.2017.09.016 · 2017 · External reference
Aberrant Selection and Function of Invariant NKT Cells in the Absence of AP‐1 Transcription Factor Fra‐2
2009 · External reference
Landscape and Dynamics of the Transcriptional Regulatory Network During Natural Killer Cell Differentiation
10.1016/j.gpb.2020.12.003 · 2020 · External reference
Single‐Cell RNA Sequencing Reveals Intra‐Tumoral Heterogeneity of Glioblastoma and a Pro‐Tumor Subset of Tumor‐Associated Macrophages Characterized by EZH2 Overexpression
10.1016/j.bbadis.2022.166534 · 2022 · External reference
Macrophage Diversity in Cancer Revisited in the Era of Single‐Cell Omics
10.1016/j.it.2022.04.008 · 2022 · External reference
Tumor Macrophage Functional Heterogeneity Can Inform the Development of Novel Cancer Therapies
10.1016/j.it.2023.10.007 · 2023 · External reference
Single‐Cell Transcriptional Atlas of Tumor‐Associated Macrophages in Breast Cancer
10.1186/s13058-024-01887-6 · 2024 · External reference
SPP1 Macrophage Polarity Identifies a Network of Cellular Programs That Control Human Cancers
10.1126/science.ade2292 · 2023 · External reference
Trajectories of Macrophage Ontogeny and Reprogramming in Cancer
10.1016/j.isci.2025.112498 · 2025 · External reference
Single‐Cell and Spatial Transcriptomics Reveal a Tumor‐Associated Macrophage Subpopulation That Mediates Prostate Cancer Progression and Metastasis
10.1158/1541-7786.mcr-24-0791 · 2025 · External reference
Tumor‐Associated Macrophage Clusters Linked to Immunotherapy in a Pan‐Cancer Census
10.1038/s41698-024-00660-4 · 2024 · External reference
Metabolic Reprogramming of Hypoxic Tumor‐Associated Macrophages Through CSF‐1R Targeting Favors Treatment Efficiency in Colorectal Cancers
10.1136/jitc-2024-009602 · 2024 · External reference
Lactic Acid Induces Transcriptional Repression of Macrophage Inflammatory Response via Histone Acetylation
10.1016/j.celrep.2024.113746 · 2024 · External reference
Lactate Supports a Metabolic‐Epigenetic Link in Macrophage Polarization
10.1126/sciadv.abi8602 · 2021 · External reference
YY1 Enhances HIF‐1α Stability in Tumor‐Associated Macrophages to Suppress Anti‐Tumor Immunity of Prostate Cancer in Mice
10.1038/s41467-025-61560-0 · 2025 · External reference
Lactate Secreted by Esophageal Cancer Cells Induces M2 Macrophage Polarization via the AKT/ERK Pathway
10.1111/1759-7714.14998 · 2023 · External reference
The Macrophage Odorant Receptor Olfr78 Mediates the Lactate‐Induced M2 Phenotype of Tumor‐Associated Macrophages
10.1073/pnas.2102434118 · 2021 · External reference
Metabolism Drives Macrophage Heterogeneity in the Tumor Microenvironment
10.1016/j.celrep.2022.110609 · 2022 · External reference
YY1 Complex in M2 Macrophage Promotes Prostate Cancer Progression by Upregulating IL‐6
10.1136/jitc-2022-006020 · 2023 · External reference
Single‐Cell and Spatial Analysis Reveals Macrophage‐T Cell Crosstalk in Non‐Small Cell Lung Cancer Immunosuppression
10.21037/tlcr-2025-912 · 2025 · External reference
Dynamic Education of Macrophages in Different Areas of Human Tumors
10.1007/s12307-012-0113-z · 2012 · External reference
Spatial Organization of Macrophages in CTL‐Rich Hepatocellular Carcinoma Influences CTL Antitumor Activity
10.1158/2326-6066.cir-24-0589 · 2025 · External reference
10.1101/2022.11.17.516850
10.1101/2022.11.17.516850 · External reference
Spatio‐Temporal Dynamics of M1 and M2 Macrophages in a Multiphase Model of Tumor Growth
10.1007/s11538-025-01466-6 · 2025 · External reference
Tumor Microenvironment in Gastric Cancers
10.1111/cas.14521 · 2020 · External reference
Metabolic Interplay Between Endometrial Cancer and Tumor‐Associated Macrophages: Lactate‐Induced M2 Polarization Enhances Tumor Progression
10.1186/s12967-025-06235-6 · 2025 · External reference
The Dynamics of the T‐Cell Antitumor Response: Chemokine‐Secreting Dendritic Cells Can Prime Tumor‐Reactive T Cells Extranodally
2001 · External reference
10.1016/j.celrep.2026.118070
10.1016/j.celrep.2026.118070 · External reference
Critical Role for Skin‐Derived Migratory DCs and Langerhans Cells in TFH and GC Responses After Intradermal Immunization
10.1016/j.jid.2017.04.016 · 2017 · External reference
LXR Signaling Controls Homeostatic Dendritic Cell Maturation
10.1126/sciimmunol.add3955 · 2023 · External reference
Metabolic Guidance and Stress in Tumors Modulate Antigen‐Presenting Cells
10.1038/s41389-022-00438-y · 2022 · External reference
Human Dendritic Cells in Cancer
10.1126/sciimmunol.abm9409 · 2022 · External reference
MerTK Induces Dysfunctional Dendritic Cells by Metabolic Reprogramming
10.1158/2326-6066.cir-23-0666 · 2024 · External reference
Dendritic Cells in Shaping Anti‐Tumor T Cell Response
10.3390/cancers16122211 · 2024 · External reference
Dendritic Cell Piezo1 Directs the Differentiation of TH1 and Treg Cells in Cancer
10.7554/elife.79957 · 2022 · External reference
Intratumoral Dendritic Cell–CD4+ T Helper Cell Niches Enable CD8+ T Cell Differentiation Following PD‐1 Blockade in Hepatocellular Carcinoma
10.1038/s41591-023-02345-0 · 2023 · External reference
Specialized Dendritic Cells Induce Tumor‐Promoting IL‐10+IL‐17+ FoxP3neg Regulatory CD4+ T Cells in Pancreatic Carcinoma
10.1038/s41467-019-09416-2 · 2019 · External reference
Neutrophil Diversity and Plasticity in Tumour Progression and Therapy
10.1038/s41568-020-0281-y · 2020 · External reference
Neutrophil Dynamics in the Tumor Microenvironment
10.1172/jci143759 · 2021 · External reference
Neutrophil Profiling Illuminates Anti‐Tumor Antigen‐Presenting Potency
10.1016/j.cell.2024.02.005 · 2024 · External reference
Liver Tumour Immune Microenvironment Subtypes and Neutrophil Heterogeneity
10.1038/s41586-022-05400-x · 2022 · External reference
A Subset of Neutrophils Activates Anti‐Tumor Immunity and Inhibits Non‐Small‐Cell Lung Cancer Progression
10.1016/j.devcel.2024.10.010 · 2025 · External reference
MYO1F in Neutrophils Is Required for the Response to Immune Checkpoint Blockade Therapy
10.1084/jem.20241957 · 2025 · External reference
PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients With Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment
10.1002/advs.202507167 · 2025 · External reference
The Recruitment of Neutrophils to the Tumor Microenvironment Is Regulated by Multiple Mediators
10.3389/fimmu.2021.734188 · 2021 · External reference
Nutrient Restriction‐Activated Fra‐2 Promotes Tumor Progression via IGF1R in miR‐15a Downmodulated Pancreatic Ductal Adenocarcinoma
10.1038/s41392-024-01740-4 · 2024 · External reference
FOSL2‐Mediated Transcription of ISG20 Induces M2 Polarization of Macrophages and Enhances Tumorigenic Ability of Glioblastoma Cells
10.1007/s11060-024-04771-7 · 2024 · External reference
Reprogramming of Tumor‐Associated Macrophages by Targeting β‐Catenin/FOSL2/ARID5A Signaling: A Potential Treatment of Lung Cancer
10.1126/sciadv.aaz6105 · 2020 · External reference
Single‐Cell Resolution Characterization of Myeloid‐Derived Cell States With Implication in Cancer Outcome
10.1038/s41467-024-49916-4 · 2024 · External reference
Mapping Immune Cell Dynamics and Macrophage Plasticity in Breast Cancer Tumor Microenvironment Through Single‐Cell Analysis
10.1007/s12672-025-02419-0 · 2025 · External reference
Fra2 Overexpression in Mice Leads to Non‐Allergic Asthma Development in an IL‐13 Dependent Manner
10.3389/fimmu.2018.02018 · 2018 · External reference
Pulmonary Fibrosis in Fra‐2 Transgenic Mice Is Associated With Decreased Numbers of Alveolar Macrophages and Increased Susceptibility to Pneumococcal Pneumonia
10.1152/ajplung.00505.2020 · 2021 · External reference
Transcriptional Changes in Dendritic Cells Underlying Allergen Specific Induced Tolerance in a Mouse Model
10.1038/s41598-022-06186-8 · 2022 · External reference
Alternatively Activated Macrophages Promote Airway Inflammation Through JAK3‐STAT5‐Fra2 in Asthma
10.1007/s00011-022-01585-z · 2022 · External reference
Fosl2 Deficiency Predisposes Mice to Osteopetrosis, Leading to Bone Marrow Failure
2024 · External reference
Transcriptional Regulation of the Mouse CD11c Promoter by AP‐1 Complex With JunD and Fra2 in Dendritic Cells
10.1016/j.molimm.2012.08.004 · 2013 · External reference
ANKRD1 Is a Mesenchymal‐Specific Driver of Cancer‐Associated Fibroblast Activation Bridging Androgen Receptor Loss to AP‐1 Activation
10.1038/s41467-024-45308-w · 2024 · External reference
Antitumor Promotion by Phenolic Antioxidants: Inhibition of AP‐1 Activity Through Induction of Fra Expression
10.1073/pnas.92.11.4972 · 1995 · External reference
Induction of Major Histocompatibility Complex Class I Molecules on Human Neuroblastoma Line Cells by a Flavoid Antioxidant
10.1016/s0304-3940(00)01748-1 · 2001 · External reference
Resveratrol (RV): A Pharmacological Review and Call for Further Research
10.1016/j.biopha.2021.112164 · 2021 · External reference
Chemosensitization of Tumor Cells by Phenolic Antioxidants: The Role of the Nrf2 Transcription Factor
10.1134/s000635092006010x · 2020 · External reference
Multispecific Targeting of Glioblastoma With Tumor Microenvironment‐Responsive Multifunctional Engineered NK Cells
10.1073/pnas.2107507118 · 2021 · External reference
iNKT: A New Avenue for CAR‐Based Cancer Immunotherapy
10.1016/j.tranon.2022.101342 · 2022 · External reference
Adoptive Immunotherapy With Engineered iNKT Cells to Target Cancer Cells and the Suppressive Microenvironment
10.3389/fmed.2022.897750 · 2022 · External reference
Tumour DDR1 Promotes Collagen Fibre Alignment to Instigate Immune Exclusion
10.1038/s41586-021-04057-2 · 2021 · External reference
Cancer Cell Metabolism and Antitumour Immunity
10.1038/s41577-024-01026-4 · 2024 · External reference
