Research graph
References from Serum Metabolomic Profiles Unveil Biomarkers and Core Metabolic Pathways in Multiple System Atrophy Patients. Local targets link to admitted publications; unresolved targets remain external evidence.
Multiple‐system atrophy
10.1056/nejmra1311488 · 2015 · External reference
Multiple system atrophy
10.1038/s41572-022-00382-6 · 2022 · External reference
Multiple system atrophy: recent developments and future perspectives
10.1002/mds.27894 · 2019 · External reference
The Movement Disorder Society criteria for the diagnosis of multiple system atrophy
10.1002/mds.29005 · 2022 · External reference
Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy
10.1136/jnnp-2017-315813 · 2018 · External reference
Artificial intelligence‐based multi‐omics analysis fuels cancer precision medicine
10.1016/j.semcancer.2022.12.009 · 2023 · External reference
Metabolomics for investigating physiological and pathophysiological processes
10.1152/physrev.00035.2018 · 2019 · External reference
Small molecule metabolites: discovery of biomarkers and therapeutic targets
10.1038/s41392-023-01399-3 · 2023 · External reference
Identification of blood metabolites associated with risk of Alzheimer's disease by integrating genomics and metabolomics data
10.1038/s41380-023-02400-9 · 2024 · External reference
Untargeted serum metabolomics reveals novel metabolite associations and disruptions in amino acid and lipid metabolism in Parkinson's disease
10.1186/s13024-023-00694-5 · 2023 · External reference
MDS clinical diagnostic criteria for Parkinson's disease
10.1002/mds.26424 · 2015 · External reference
No correlation between plasma GPNMB levels and multiple system atrophy in Chinese cohorts
10.1002/mds.29566 · 2023 · External reference
Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction
10.1093/brain/awaa110 · 2020 · External reference
Accurate measurement of endogenous adenosine in human blood
10.1371/journal.pone.0205707 · 2018 · External reference
Multidimensional biomarkers for multiple system atrophy: an update and future directions
10.1186/s40035-023-00370-0 · 2023 · External reference
Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy
10.1371/journal.pone.0223113 · 2019 · External reference
Plasma metabolite markers of Parkinson's disease and atypical parkinsonism
10.3390/metabo11120860 · 2021 · External reference
Riboflavin: the health benefits of a forgotten natural vitamin
10.3390/ijms21030950 · 2020 · External reference
Riboflavin in neurological diseases: a narrative review
10.1007/s40261-021-01038-1 · 2021 · External reference
Systematic genome assessment of B‐vitamin biosynthesis suggests co‐operation among gut microbes
10.3389/fgene.2015.00148 · 2015 · External reference
Gut microbiota‐derived metabolites in the regulation of host immune responses and immune‐related inflammatory diseases
10.1038/s41423-021-00661-4 · 2021 · External reference
Alterations of the gut microbiota in multiple system atrophy patients
10.3389/fnins.2019.01102 · 2019 · External reference
Altered gut microbiome and metabolome in patients with multiple system atrophy
10.1002/mds.27203 · 2018 · External reference
Meta‐analysis of shotgun sequencing of gut microbiota in Parkinson's disease
10.1038/s41531-024-00724-z · 2024 · External reference
High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients
10.1590/s0100-879x2003001000019 · 2003 · External reference
Serum vitamin levels in multiple system atrophy: a case‐control study
10.3389/fnagi.2022.1105019 · 2022 · External reference
Mucosal‐associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function
10.1038/s41590-022-01349-1 · 2022 · External reference
Avoidance of MAIT cells is an essential determinant of listeria monocytogenes pathogenesis
10.1073/pnas.2601925123 · 2026 · External reference
Synergistic TCR‐independent action of IL‐33 and IL‐12 drive a potent IFNγ secretory program in human circulating MAIT cells with immunomodulatory properties
10.3389/fimmu.2026.1852383 · 2026 · External reference
From purines to purinergic signalling: molecular functions and human diseases
10.1038/s41392-021-00553-z · 2021 · External reference
Purinergic signalling and neurological diseases: an update
10.2174/1871527315666160922104848 · 2017 · External reference
Purinergic receptors in neurological diseases with motor symptoms: targets for therapy
10.3389/fphar.2018.00325 · 2018 · External reference
Stress‐induced metabolic disorder in peripheral CD4(+) T cells leads to anxiety‐like behavior
10.1016/j.cell.2019.10.001 · 2019 · External reference
The pentose phosphate pathway in health and disease
10.1038/s42255-023-00863-2 · 2023 · External reference
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
10.1111/brv.12140 · 2015 · External reference
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
10.1186/s12974-019-1659-1 · 2019 · External reference
Branched chain amino acids: beyond nutrition metabolism
10.3390/ijms19040954 · 2018 · External reference
Insulin resistance and impaired branched‐chain amino acid metabolism in Alzheimer's disease
10.3233/jad-221147 · 2023 · External reference
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria
10.1073/pnas.2009838117 · 2020 · External reference
Proline metabolic reprogramming modulates cardiac remodeling induced by pressure overload in the heart
10.1126/sciadv.adl3549 · 2024 · External reference
L‐Arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut
10.1080/19490976.2023.2222961 · 2023 · External reference
Arginine‐dependent immune responses
10.1007/s00018-021-03828-4 · 2021 · External reference
L‐Arginine inhibited inflammatory response and oxidative stress induced by lipopolysaccharide via arginase‐1 signaling in IPEC‐J2 cells
10.3390/ijms20071800 · 2019 · External reference
MDS clinical diagnostic criteria for Parkinson's disease
10.1002/mds.26424 · ExternalCitation · doi-reference
Altered gut microbiome and metabolome in patients with multiple system atrophy
10.1002/mds.27203 · ExternalCitation · doi-reference
Multiple system atrophy: recent developments and future perspectives
10.1002/mds.27894 · ExternalCitation · doi-reference
The Movement Disorder Society criteria for the diagnosis of multiple system atrophy
10.1002/mds.29005 · ExternalCitation · doi-reference
No correlation between plasma GPNMB levels and multiple system atrophy in Chinese cohorts
10.1002/mds.29566 · ExternalCitation · doi-reference
Arginine‐dependent immune responses
10.1007/s00018-021-03828-4 · ExternalCitation · doi-reference
Riboflavin in neurological diseases: a narrative review
10.1007/s40261-021-01038-1 · ExternalCitation · doi-reference
Stress‐induced metabolic disorder in peripheral CD4(+) T cells leads to anxiety‐like behavior
10.1016/j.cell.2019.10.001 · ExternalCitation · doi-reference
Artificial intelligence‐based multi‐omics analysis fuels cancer precision medicine
10.1016/j.semcancer.2022.12.009 · ExternalCitation · doi-reference
Identification of blood metabolites associated with risk of Alzheimer's disease by integrating genomics and metabolomics data
10.1038/s41380-023-02400-9 · ExternalCitation · doi-reference
From purines to purinergic signalling: molecular functions and human diseases
10.1038/s41392-021-00553-z · ExternalCitation · doi-reference
Small molecule metabolites: discovery of biomarkers and therapeutic targets
10.1038/s41392-023-01399-3 · ExternalCitation · doi-reference
Gut microbiota‐derived metabolites in the regulation of host immune responses and immune‐related inflammatory diseases
10.1038/s41423-021-00661-4 · ExternalCitation · doi-reference
Meta‐analysis of shotgun sequencing of gut microbiota in Parkinson's disease
10.1038/s41531-024-00724-z · ExternalCitation · doi-reference
Multiple system atrophy
10.1038/s41572-022-00382-6 · ExternalCitation · doi-reference
Mucosal‐associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function
10.1038/s41590-022-01349-1 · ExternalCitation · doi-reference
The pentose phosphate pathway in health and disease
10.1038/s42255-023-00863-2 · ExternalCitation · doi-reference
Multiple‐system atrophy
10.1056/nejmra1311488 · ExternalCitation · doi-reference
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria
10.1073/pnas.2009838117 · ExternalCitation · doi-reference
Avoidance of MAIT cells is an essential determinant of listeria monocytogenes pathogenesis
10.1073/pnas.2601925123 · ExternalCitation · doi-reference
L‐Arginine metabolism as pivotal interface of mutual host–microbe interactions in the gut
10.1080/19490976.2023.2222961 · ExternalCitation · doi-reference
Reduced oligodendrocyte exosome secretion in multiple system atrophy involves SNARE dysfunction
10.1093/brain/awaa110 · ExternalCitation · doi-reference
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
10.1111/brv.12140 · ExternalCitation · doi-reference
Proline metabolic reprogramming modulates cardiac remodeling induced by pressure overload in the heart
10.1126/sciadv.adl3549 · ExternalCitation · doi-reference
Recent advances in neuropathology, biomarkers and therapeutic approach of multiple system atrophy
10.1136/jnnp-2017-315813 · ExternalCitation · doi-reference
Metabolomics for investigating physiological and pathophysiological processes
10.1152/physrev.00035.2018 · ExternalCitation · doi-reference
The pentose phosphate pathway regulates chronic neuroinflammation and dopaminergic neurodegeneration
10.1186/s12974-019-1659-1 · ExternalCitation · doi-reference
Untargeted serum metabolomics reveals novel metabolite associations and disruptions in amino acid and lipid metabolism in Parkinson's disease
10.1186/s13024-023-00694-5 · ExternalCitation · doi-reference
Multidimensional biomarkers for multiple system atrophy: an update and future directions
10.1186/s40035-023-00370-0 · ExternalCitation · doi-reference
Accurate measurement of endogenous adenosine in human blood
10.1371/journal.pone.0205707 · ExternalCitation · doi-reference
Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy
10.1371/journal.pone.0223113 · ExternalCitation · doi-reference
High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients
10.1590/s0100-879x2003001000019 · ExternalCitation · doi-reference
Purinergic signalling and neurological diseases: an update
10.2174/1871527315666160922104848 · ExternalCitation · doi-reference
Insulin resistance and impaired branched‐chain amino acid metabolism in Alzheimer's disease
10.3233/jad-221147 · ExternalCitation · doi-reference
Systematic genome assessment of B‐vitamin biosynthesis suggests co‐operation among gut microbes
10.3389/fgene.2015.00148 · ExternalCitation · doi-reference
Synergistic TCR‐independent action of IL‐33 and IL‐12 drive a potent IFNγ secretory program in human circulating MAIT cells with immunomodulatory properties
10.3389/fimmu.2026.1852383 · ExternalCitation · doi-reference
Serum vitamin levels in multiple system atrophy: a case‐control study
10.3389/fnagi.2022.1105019 · ExternalCitation · doi-reference
Alterations of the gut microbiota in multiple system atrophy patients
10.3389/fnins.2019.01102 · ExternalCitation · doi-reference
Purinergic receptors in neurological diseases with motor symptoms: targets for therapy
10.3389/fphar.2018.00325 · ExternalCitation · doi-reference
Branched chain amino acids: beyond nutrition metabolism
10.3390/ijms19040954 · ExternalCitation · doi-reference
L‐Arginine inhibited inflammatory response and oxidative stress induced by lipopolysaccharide via arginase‐1 signaling in IPEC‐J2 cells
10.3390/ijms20071800 · ExternalCitation · doi-reference
Riboflavin: the health benefits of a forgotten natural vitamin
10.3390/ijms21030950 · ExternalCitation · doi-reference
Plasma metabolite markers of Parkinson's disease and atypical parkinsonism
10.3390/metabo11120860 · ExternalCitation · doi-reference