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References from <scp>tsRNAs</scp> Mediate Intergenerational Inheritance by Concertedly Suppressing Wnt and <scp>PPAR</scp> Pathways. Local targets link to admitted publications; unresolved targets remain external evidence.
Origins of Lifetime Health Around the Time of Conception: Causes and Consequences
10.1016/s0140-6736(18)30312-x · 2018 · External reference
Maternal Inheritance of Glucose Intolerance via Oocyte TET3 Insufficiency
10.1038/s41586-022-04756-4 · 2022 · External reference
The Epigenetic Mechanisms Underlying Gamete Origin of Adult‐Onset Diseases
10.1016/j.scib.2022.07.030 · 2022 · External reference
Paternal Exercise Confers Endurance Capacity to Offspring Through Sperm microRNAs
10.1016/j.cmet.2025.09.003 · 2025 · External reference
Vitamin C‐Dependent Intergenerational Inheritance of Enhanced Endurance Performance Following Maternal Exercise
10.1002/advs.202408912 · 2025 · External reference
EZHIP Restricts Noncanonical PRC2 Binding and Regulates H3K27me3 Intergenerational Inheritance and Reprogramming
10.1016/j.stem.2025.09.009 · 2025 · External reference
Sperm RNA Code Programmes the Metabolic Health of Offspring
10.1038/s41574-019-0226-2 · 2019 · External reference
Origins and Evolving Functionalities of tRNA‐Derived Small RNAs
10.1016/j.tibs.2021.05.001 · 2021 · External reference
Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals
10.1016/j.cell.2010.12.008 · 2010 · External reference
Sperm tsRNAs Contribute to Intergenerational Inheritance of an Acquired Metabolic Disorder
10.1126/science.aad7977 · 2016 · External reference
Biogenesis and Function of tRNA Fragments During Sperm Maturation and Fertilization in Mammals
10.1126/science.aad6780 · 2016 · External reference
Early Life Stress in Fathers Improves Behavioural Flexibility in Their Offspring
10.1038/ncomms6466 · 2014 · External reference
Reproductive Toxicity of Low Level Bisphenol A Exposures in a Two‐Generation Zebrafish Assay: Evidence of Male‐Specific Effects
10.1016/j.aquatox.2015.10.020 · 2015 · External reference
Reproductive and Developmental F1 Toxicity Following Exposure of Pubescent F0 Male Mice to Bisphenol A Alone and in a Combination With X‐Rays Irradiation
10.1016/j.tox.2018.10.007 · 2018 · External reference
Transgenerational Effects of di‐(2‐Ethylhexyl) Phthalate on Testicular Germ Cell Associations and Spermatogonial Stem Cells in Mice
10.1095/biolreprod.112.106104 · 2013 · External reference
Cadmium: Toxic Effects on the Reproductive System and the Embryo
10.1016/j.reprotox.2008.02.001 · 2008 · External reference
Cross‐Talk Between Autophagy and Apoptosis Regulates Testicular Injury/Recovery Induced by Cadmium via PI3K With mTOR‐Independent Pathway
10.1038/s41419-020-2246-1 · 2020 · External reference
Cadmium Attenuates Testosterone Synthesis by Promoting Ferroptosis and Blocking Autophagosome‐Lysosome Fusion
10.1016/j.freeradbiomed.2021.09.028 · 2021 · External reference
Cadmium Exposure Induces Pyroptosis in Testicular Tissue by Increasing Oxidative Stress and Activating the AIM2 Inflammasome Pathway
10.1016/j.scitotenv.2022.157500 · 2022 · External reference
Sex‐Dependent Effects of Cadmium Exposure in Early Life on Gut Microbiota and Fat Accumulation in Mice
10.1289/ehp360 · 2017 · External reference
Effects of Periconception Cadmium and Mercury co‐Administration to Mice on Indices of Chronic Diseases in Male Offspring at Maturity
10.1289/ehp481 · 2017 · External reference
Paternal Cadmium Exposure Increases the Susceptibility to Diet‐Induced Testicular Injury and Spermatogenic Disorders in Mouse Offspring
10.1016/j.chemosphere.2019.125776 · 2020 · External reference
Paternal Cadmium Exposure Induces Glucolipid Metabolic Reprogramming in Offspring Mice via PPAR Signaling Pathway
10.1016/j.chemosphere.2023.139592 · 2023 · External reference
Paternal Cadmium Exposure Affects Testosterone Synthesis by Reducing the Testicular Cholesterol Pool in Offspring Mice
10.1016/j.ecoenv.2022.113947 · 2022 · External reference
Paternal Cadmium Exposure Affects Estradiol Synthesis by Impairing Intracellular Cholesterol Homeostasis and Mitochondrial Function in Offspring Female Mice
10.1016/j.ecoenv.2023.115280 · 2023 · External reference
Cancer Metabolism: Looking Forward
10.1038/s41568-021-00378-6 · 2021 · External reference
The Intersection of Epigenetics and Metabolism in Trained Immunity
10.1016/j.immuni.2020.10.011 · 2021 · External reference
Functional Role of PPARs in Ruminants: Potential Targets for Fine‐Tuning Metabolism During Growth and Lactation
10.1155/2013/684159 · 2013 · External reference
Peroxisome Proliferator‐Activated Receptor Delta Regulates Lipid Droplet Formation and Transport in Goat Mammary Epithelial Cells
10.3168/jds.2017-13543 · 2018 · External reference
A Novel Class of tRNA‐Derived Small RNAs Extremely Enriched in Mature Mouse Sperm
10.1038/cr.2012.141 · 2012 · External reference
Differential Expression Profiles and Potential Intergenerational Functions of tRNA‐Derived Small RNAs in Mice After Cadmium Exposure
10.3389/fcell.2021.791784 · 2021 · External reference
HISAT: A Fast Spliced Aligner With Low Memory Requirements
10.1038/nmeth.3317 · 2015 · External reference
RSEM: Accurate Transcript Quantification From RNA‐Seq Data With or Without a Reference Genome
10.1186/1471-2105-12-323 · 2011 · External reference
Moderated Estimation of Fold Change and Dispersion for RNA‐Seq Data With DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Limma Powers Differential Expression Analyses for RNA‐Sequencing and Microarray Studies
10.1093/nar/gkv007 · 2015 · External reference
clusterProfiler 4.0: A Universal Enrichment Tool for Interpreting Omics Data
2021 · External reference
ReactomePA: An R/Bioconductor Package for Reactome Pathway Analysis and Visualization
10.1039/c5mb00663e · 2016 · External reference
Persistent Wnt Signaling Affects IVF Embryo Implantation and Offspring Metabolism
10.1016/j.scib.2025.05.003 · 2025 · External reference
Developmental Regulation of Barrier‐ and Non‐Barrier Blood Vessels in the CNS
10.1111/joim.13263 · 2022 · External reference
Multi‐Layered Prevention and Treatment of Chronic Inflammation, Organ Fibrosis and Cancer Associated With Canonical WNT/β‐Catenin Signaling Activation (Review)
2018 · External reference
Wnt/β‐Catenin Pathway‐Mediated PPARδ Expression During Embryonic Development Differentiation and Disease
10.3390/ijms22041854 · 2021 · External reference
Interrelationship of Canonical and Non‐Canonical Wnt Signalling Pathways in Chronic Metabolic Diseases
10.1177/1479164117738442 · 2018 · External reference
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2025
10.1093/nar/gkae978 · 2025 · External reference