Research graph
References from Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer Statistics 2022: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2024 · External reference
Isolation of a Human Prostate Carcinoma Cell Line (DU 145)
10.1002/ijc.2910210305 · 1978 · External reference
Establishment and Characterization of a Human Prostatic Carcinoma Cell Line (PC‐3)
1979 · External reference
LNCaP Model of Human Prostatic Carcinoma
1983 · External reference
Cellular and Molecular Progression of Prostate Cancer: Models for Basic and Preclinical Research
10.3390/cancers12092651 · 2020 · External reference
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
10.1126/science.1117679 · 2005 · External reference
Differential Expression of 5α‐reductase Isoenzymes in the Human Prostate and Prostatic Carcinomas
10.1002/(sici)1097-0045(199610)29:4<261::aid-pros7>3.0.co;2-e · 1996 · External reference
Molecular Characterization of Human Prostate Carcinoma Cell Lines
10.1002/pros.10290 · 2003 · External reference
Cell Lines Used in Prostate Cancer Research: A Compendium of Old and New Lines, Part 1
10.1097/01.ju.0000141580.30910.57 · 2005 · External reference
Cell Lines Used in Prostate Cancer Research: A Compendium of Old and New Lines, Part 2
10.1097/01.ju.0000149989.01263.dc · 2005 · External reference
In Vitro and In Vivo Model Systems Used in Prostate Cancer Research
10.14440/jbm.2015.63 · 2015 · External reference
Application of Prostate Cancer Models for Preclinical Study: Advantages and Limitations of Cell Lines, Patient‐Derived Xenografts, and Three‐Dimensional Culture of Patient‐Derived Cells
10.3390/cells8010074 · 2019 · External reference
Immortalized and Tumorigenic Adult Human Prostatic Epithelial Cell Lines: Characteristics and Applications Part I. Cell Markers and Immortalized Nontumorigenic Cell Lines
10.1002/(sici)1097-0045(199612)29:6<386::aid-pros7>3.0.co;2-6 · 1996 · External reference
Immortalized and Tumorigenic Adult Human Prostatic Epithelial Cell Lines: Characteristics and Applications. Part 2. Tumorigenic Cell Lines
10.1002/(sici)1097-0045(19970101)30:1<58::aid-pros9>3.0.co;2-h · 1997 · External reference
Organoid Cultures Derived From Patients With Advanced Prostate Cancer
10.1016/j.cell.2014.08.016 · 2014 · External reference
Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures
10.1016/j.cell.2014.08.017 · 2014 · External reference
Check Your Cultures! A List of Cross‐Contaminated or Misidentified Cell Lines
10.1002/ijc.25242 · 2010 · External reference
Recombinant Origin of the Retrovirus XMRV
10.1126/science.1205292 · 2011 · External reference
Molecular Characterization of TMPRSS2‐ERG Gene Fusion in the NCI‐H660 Prostate Cancer Cell Line: A New Perspective for an Old Model
10.1593/neo.07103 · 2007 · External reference
Widely Used Prostate Carcinoma Cell Lines Share Common Origins
10.1002/pros.1045 · 2001 · External reference
Immortalization of Human Adult Normal Prostatic Epithelial Cells by Liposomes Containing Large T‐SV40 Gene
10.1016/s0022-5347(17)37953-3 · 1991 · External reference
Functional Expression of SV40 in Normal Human Prostatic Epithelial and Fibroblastic Cells: Differentiation Pattern of Nontumorigenic Cell Lines
1995 · External reference
Human Prostatic Cell Line PNT1A, a Useful Tool for Studying Androgen Receptor Transcriptional Activity and Its Differential Subnuclear Localization in the Presence of Androgens and Antiandrogens
10.1016/s0303-7207(01)00669-4 · 2001 · External reference
Androgen Responsive Adult Human Prostatic Epithelial Cell Lines Immortalized by Human Papillomavirus 18
10.1093/carcin/18.6.1215 · 1997 · External reference
Stepwise Immortalization and Transformation of Adult Human Prostate Epithelial Cells by a Combination of HPV‐18 and v‐Ki‐ras
10.1073/pnas.91.25.11874 · 1994 · External reference
Establishment and Characterization of an Immortalized but Non‐Transformed Human Prostate Epithelial Cell Line: BPH‐1
10.1007/bf02631333 · 1995 · External reference
Characterization of Adult Human Prostatic Epithelial Cells Immortalized by Polybrene‐Induced DNA Transfection with a Plasmid Containing an Origin‐Defective SV40 Genome
1994 · External reference
The Oncogenic Potential of a Prostate Cancer‐Derived Androgen Receptor Mutant
10.1002/pros.20544 · 2007 · External reference
Establishment and Characterization of a Pair of Non‐Malignant and Malignant Tumor Derived Cell Lines from an African American Prostate Cancer Patient
2010 · External reference
Proteomic Characterization of Paired Non‐Malignant and Malignant African‐American Prostate Epithelial Cell Lines Distinguishes Them by Structural Proteins
10.1186/s12885-017-3462-7 · 2017 · External reference
Differential Cytokeratin Expression in Normal, Hyperplastic and Malignant Epithelial Cells from Human Prostate
10.1016/s0022-5347(17)39903-2 · 1990 · External reference
A Human Prostatic Stromal Myofibroblast Cell Line WPMY‐1: A Model for Stromal‐Epithelial Interactions in Prostatic Neoplasia
10.1093/carcin/20.7.1185 · 1999 · External reference
Leptin Mediates Prostate Stromal Cell Proliferation, Smooth Muscle Contraction, and Mitochondrial Function in Benign Prostate Hyperplasia
10.2147/dmso.s420258 · 2023 · External reference
Effects of Androgen Receptor and Androgen on Gene Expression in Prostate Stromal Fibroblasts and Paracrine Signaling to Prostate Cancer Cells
10.1371/journal.pone.0016027 · 2011 · External reference
PC3 Is a Cell Line Characteristic of Prostatic Small Cell Carcinoma
10.1002/pros.21383 · 2011 · External reference
Characteristics of the Biphasic Action of Androgens and of the Potent Antiproliferative Effects of the New Pure Antiestrogen EM‐139 on Cell Cycle Kinetic Parameters in LNCaP Human Prostatic Cancer Cells
1991 · External reference
A Mutation in the Ligand Binding Domain of the Androgen Receptor of Human INCaP Cells Affects Steroid Binding Characteristics and Response to Anti‐Androgens
10.1016/s0006-291x(05)80067-1 · 1990 · External reference
Derivation of Androgen‐Independent Human LNCaP Prostatic Cancer Cell Sublines: Role of Bone Stromal Cells
10.1002/ijc.2910570319 · 1994 · External reference
Androgen‐Independent Cancer Progression and Bone Metastasis in the LNCaP Model of Human Prostate Cancer
1994 · External reference
VCaP, a Cell‐Based Model System of Human Prostate Cancer
2001 · External reference
Progression of Metastatic Human Prostate Cancer to Androgen Independence in Immunodeficient SCID Mice
10.1038/nm0497-402 · 1997 · External reference
Evidence for Clonal Outgrowth of Androgen‐Independent Prostate Cancer Cells From Androgen‐Dependent Tumors through a Two‐Step Process
1999 · External reference
Establishment of Two Human Prostate Cancer Cell Lines Derived From a Single Bone Metastasis
1997 · External reference
Enhanced Androgen Receptor Signaling Correlates With the Androgen‐Refractory Growth in a Newly Established MDA PCa 2b‐hr Human Prostate Cancer Cell Subline
2003 · External reference
LuCaP 35: A New Model of Prostate Cancer Progression to Androgen Independence
10.1002/pros.10198 · 2003 · External reference
LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease and Serve as Models for Evaluating Cancer Therapeutics
10.1002/pros.23313 · 2017 · External reference
Inactivation of the Tumor Suppressor PTEN/MMAC1 in Advanced Human Prostate Cancer through Loss of Expression
10.1073/pnas.95.9.5246 · 1998 · External reference
A New Human Prostate Carcinoma Cell Line, 22Rv1
10.1007/s11626-999-0115-4 · 1999 · External reference
Ligand‐Independent Androgen Receptor Variants Derived from Splicing of Cryptic Exons Signify Hormone‐Refractory Prostate Cancer
10.1158/0008-5472.can-08-2764 · 2009 · External reference
Splicing of a Novel Androgen Receptor Exon Generates a Constitutively Active Androgen Receptor That Mediates Prostate Cancer Therapy Resistance
10.1158/0008-5472.can-08-0594 · 2008 · External reference
Dehydroepiandrosterone Activates Mutant Androgen Receptors Expressed in the Androgen‐Dependent Human Prostate Cancer Xenograft CWR22 and LNCaP Cells
10.1210/mend.11.4.9906 · 1997 · External reference
Characterization of a Novel Androgen Receptor Mutation in a Relapsed CWR22 Prostate Cancer Xenograft and Cell Line
2002 · External reference
Androgen Receptor Stabilization in Recurrent Prostate Cancer Is Associated with Hypersensitivity to Low Androgen
2001 · External reference
Characterization of Fibroblast‐Free CWR‐R1ca Castration‐Recurrent Prostate Cancer Cell Line
10.1002/pros.23190 · 2016 · External reference
p53 Oncogene Mutations in Three Human Prostate Cancer Cell Lines
10.1002/pros.2990230206 · 1993 · External reference
The DU145 Human Prostate Carcinoma Cell Line Harbors a Temperature‐Sensitive Allele of p53
10.1002/pros.20462 · 2006 · External reference
DU‐145 and PC‐3 Human Prostate Cancer Cell Lines Express Androgen Receptor: Implications for the Androgen Receptor Functions and Regulation
10.1016/j.febslet.2006.03.041 · 2006 · External reference
Androgen Receptor Expression in Androgen‐Independent Prostate Cancer Cell Lines
10.1002/pros.1048 · 2001 · External reference
Androgen‐Repressed Phenotype in Human Prostate Cancer
10.1073/pnas.93.26.15152 · 1996 · External reference
Organoid Culture Systems for Prostate Epithelial and Cancer Tissue
10.1038/nprot.2016.006 · 2016 · External reference
Metastatic Prostate Cancer in a Transgenic Mouse
1996 · External reference
Dissociation of Epithelial and Neuroendocrine Carcinoma Lineages in the Transgenic Adenocarcinoma of Mouse Prostate Model of Prostate Cancer
10.2353/ajpath.2008.070602 · 2008 · External reference
Development, Progression, and Androgen‐Dependence of Prostate Tumors in Probasin‐Large T Antigen Transgenic Mice: A Model for Prostate Cancer
1998 · External reference
A Probasin‐Large T Antigen Transgenic Mouse Line Develops Prostate Adenocarcinoma and Neuroendocrine Carcinoma With Metastatic Potential
2001 · External reference
Prostate‐Specific Deletion of the Murine Pten Tumor Suppressor Gene Leads to Metastatic Prostate Cancer
10.1016/s1535-6108(03)00215-0 · 2003 · External reference
SMAD4‐dependent Barrier Constrains Prostate Cancer Growth and Metastatic Progression
10.1038/nature09677 · 2011 · External reference
Myc‐Driven Murine Prostate Cancer Shares Molecular Features With Human Prostate Tumors
10.1016/s1535-6108(03)00197-1 · 2003 · External reference
Prostate Intraepithelial Neoplasia Induced by Prostate Restricted Akt Activation: The MPAKT Model
10.1073/pnas.1232229100 · 2003 · External reference
The Lobund‐Wistar Rat Model of Prostate Cancer
10.1002/jcb.240501220 · 1992 · External reference
Enzalutamide Inhibits Testosterone‐Induced Growth of Human Prostate Cancer Xenografts in Zebrafish and Can Induce Bradycardia
10.1038/s41598-017-14413-w · 2017 · External reference
Genetics and Biology of Prostate Cancer
10.1101/gad.315739.118 · 2018 · External reference
