Research graph
References from Comparison of Gene Enrichment Between Prostate Tissue and Urine for Non‐Invasive Biomarker Development. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Standardization of Gleason Grading among 337 European Pathologists
10.1111/his.12008 · 2013 · External reference
Biopsy Criteria for Determining Appropriateness for Active Surveillance in the Modern Era
10.1016/j.urology.2013.12.054 · 2014 · External reference
Overdiagnosis and Overtreatment of Prostate Cancer
10.1016/j.eururo.2013.12.062 · 2014 · External reference
Optimizing Active Surveillance Strategies to Balance the Competing Goals of Early Detection of Grade Progression and Minimizing Harm from Biopsies
10.1002/cncr.31101 · 2018 · External reference
Systematic Review of Complications of Prostate Biopsy
10.1016/j.eururo.2013.05.049 · 2013 · External reference
Development and Preliminary Clinical Application of Circulating Tumor Cell Detection System for Prostate Cancer
10.1166/jbn.2019.2706 · 2019 · External reference
A Novel Urine Exosome Gene Expression Assay to Predict High‐Grade Prostate Cancer at Initial Biopsy
10.1001/jamaoncol.2016.0097 · 2016 · External reference
Unravelling the Proteomic Landscape of Extracellular Vesicles in Prostate Cancer by Density‐Based Fractionation of Urine
10.1080/20013078.2020.1736935 · 2020 · External reference
TMPRSS2‐ERG Fusion Transcripts in Matched Urine and Needle Rinse Material After Biopsy for the Detection of Prostate Cancer
10.1373/clinchem.2012.192260 · 2013 · External reference
Stromal Gene Expression Is Predictive for Metastatic Primary Prostate Cancer
10.1016/j.eururo.2017.02.038 · 2018 · External reference
The Relationship between T‐Lymphocyte Subset Infiltration and Survival in Patients with Prostate Cancer
10.1038/sj.bjc.6601943 · 2004 · External reference
Expression Changes in the Stroma of Prostate Cancer Predict Subsequent Relapse
10.1371/journal.pone.0041371 · 2012 · External reference
Cellular Constituents of the Prostate Stroma: Key Contributors to Prostate Cancer Progression and Therapy Resistance
10.1101/cshperspect.a030510 · 2018 · External reference
Hallmarks of Cancer: The Next Generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
Regulation of Prostate Cancer Progression by the Tumor Microenvironment
10.1016/j.canlet.2015.12.022 · 2016 · External reference
Distribution of 15 Human Kallikreins in Tissues and Biological Fluids
10.1373/clinchem.2007.088104 · 2007 · External reference
Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer
10.1097/ju.0000000000001066 · 2020 · External reference
Identification of Prostate Cancer Biomarkers in Urinary Exosomes
10.18632/oncotarget.4851 · 2015 · External reference
Identification of a Candidate Gene Panel for the Early Diagnosis of Prostate Cancer
10.1158/1078-0432.ccr-14-3334 · 2015 · External reference
CD90/THY1 Is Overexpressed in Prostate Cancer‐Associated Fibroblasts and Could Serve as a Cancer Biomarker
10.1038/modpathol.2010.122 · 2010 · External reference
SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor
10.1158/1078-0432.ccr-14-3308 · 2015 · External reference
CellMarker 2.0: An Updated Database of Manually Curated Cell Markers in Human/Mouse and Web Tools Based on scRNA‐Seq Data
10.1093/nar/gkac947 · 2023 · External reference
The Proteogenomic Landscape of Curable Prostate Cancer
10.1016/j.ccell.2019.02.005 · 2019 · External reference
Identification of Stromally Expressed Molecules in the Prostate by Tag‐Profiling of Cancer‐Associated Fibroblasts, Normal Fibroblasts and Fetal Prostate
10.1038/onc.2011.312 · 2012 · External reference
Integrative Metabolic and Transcriptomic Profiling of Prostate Cancer Tissue Containing Reactive Stroma
10.1038/s41598-018-32549-1 · 2018 · External reference
Spatial Maps of Prostate Cancer Transcriptomes Reveal an Unexplored Landscape of Heterogeneity
10.1038/s41467-018-04724-5 · 2018 · External reference
Stromal and Epithelial Transcriptional Map of Initiation Progression and Metastatic Potential of Human Prostate Cancer
10.1038/s41467-017-00460-4 · 2017 · External reference
In Silico Dissection of Cell‐Type‐Associated Patterns of Gene Expression in Prostate Cancer
10.1073/pnas.2536479100 · 2004 · External reference
Immunohistochemical Localization of Zn‐Alpha 2‐glycoprotein in Normal Human Tissues
10.1177/39.9.1918940 · 1991 · External reference
The Comprehensive Role of E‐Cadherin in Maintaining Prostatic Epithelial Integrity during Oncogenic Transformation and Tumor Progression
10.1371/journal.pgen.1008451 · 2019 · External reference
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
10.1016/j.celrep.2018.11.086 · 2018 · External reference
Adjusting Batch Effects in Microarray Expression Data Using Empirical Bayes Methods
10.1093/biostatistics/kxj037 · 2007 · External reference
The Sva Package for Removing Batch Effects and Other Unwanted Variation in High‐Throughput Experiments
10.1093/bioinformatics/bts034 · 2012 · External reference
Comprehensive Analysis of RNA Expression Correlations between Biofluids and Human Tissues
10.3390/genes12060935 · 2021 · External reference
Gene Expression Studies in Prostate Cancer Tissue: Which Reference Gene Should Be Selected for Normalization?
10.1007/s00109-005-0703-z · 2005 · External reference
Analytical Validation of an mRNA‐Based Urine Test to Predict the Presence of High‐Grade Prostate Cancer
10.1186/s41231-017-0014-8 · 2017 · External reference
Urinary Biomarkers for the Detection of Prostate Cancer in Patients with High‐Grade Prostatic Intraepithelial Neoplasia
10.1002/pros.22995 · 2015 · External reference
Unresolved reference
External reference
CD4+CD25high T Cells Are Enriched in the Tumor and Peripheral Blood of Prostate Cancer Patients
10.4049/jimmunol.177.10.7398 · 2006 · External reference
Integrated Urinary and Tissue Proteomic Signatures Reveal Core and Progression Biomarkers in MRI‐Visible and MRI‐Non‐Visible Prostate Cancer
10.3390/life16030383 · 2026 · External reference
Urinary Extracellular Vesicles Contain Mature Transcriptome Enriched in Circular and Long Noncoding RNAs with Functional Significance in Prostate Cancer
10.1002/jev2.12210 · 2022 · External reference
Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes
10.1038/s41467-024-49424-5 · 2024 · External reference
Gross Hematuria in Patients with Prostate Cancer: Etiology and Management
10.1155/2013/685327 · 2013 · External reference
Hematuria Following Post‐Prostatectomy Radiotherapy: Incidence Increases with Long‐Term Followup
10.1097/ju.0000000000002443 · 2022 · External reference
Conventional and PD‐L1‐expressing Regulatory T Cells Are Enriched during BCG Therapy and May Limit Its Efficacy
10.1016/j.eururo.2018.06.045 · 2018 · External reference
Roles of Regulatory T Cell‐Derived Extracellular Vesicles in Human Diseases
10.3390/ijms231911206 · 2022 · External reference
The Controversial Relationship between Benign Prostatic Hyperplasia and Prostate Cancer: The Role of Inflammation
10.1016/j.eururo.2011.03.055 · 2011 · External reference
Prognostic Value of Inflammation in Prostate Cancer Progression and Response to Therapeutic: A Critical Review
10.1186/s12950-016-0143-2 · 2016 · External reference
Identification of Prostate‐Enriched Proteins by In‐Depth Proteomic Analyses of Expressed Prostatic Secretions in Urine
10.1021/pr2011236 · 2012 · External reference
Inhibition of STAT3 Augments Antitumor Efficacy of anti‐CTLA‐4 Treatment against Prostate Cancer
10.1007/s00262-021-02915-6 · 2021 · External reference
Multimodal Biomarkers that Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance
10.1097/ju.0000000000003507 · 2023 · External reference
A Novel Urine Exosome Gene Expression Assay to Predict High‐Grade Prostate Cancer at Initial Biopsy
10.1001/jamaoncol.2016.0097 · ExternalCitation · doi-reference
Optimizing Active Surveillance Strategies to Balance the Competing Goals of Early Detection of Grade Progression and Minimizing Harm from Biopsies
10.1002/cncr.31101 · ExternalCitation · doi-reference
Urinary Extracellular Vesicles Contain Mature Transcriptome Enriched in Circular and Long Noncoding RNAs with Functional Significance in Prostate Cancer
10.1002/jev2.12210 · ExternalCitation · doi-reference
Urinary Biomarkers for the Detection of Prostate Cancer in Patients with High‐Grade Prostatic Intraepithelial Neoplasia
10.1002/pros.22995 · ExternalCitation · doi-reference
Gene Expression Studies in Prostate Cancer Tissue: Which Reference Gene Should Be Selected for Normalization?
10.1007/s00109-005-0703-z · ExternalCitation · doi-reference
Inhibition of STAT3 Augments Antitumor Efficacy of anti‐CTLA‐4 Treatment against Prostate Cancer
10.1007/s00262-021-02915-6 · ExternalCitation · doi-reference
Regulation of Prostate Cancer Progression by the Tumor Microenvironment
10.1016/j.canlet.2015.12.022 · ExternalCitation · doi-reference
The Proteogenomic Landscape of Curable Prostate Cancer
10.1016/j.ccell.2019.02.005 · ExternalCitation · doi-reference
Hallmarks of Cancer: The Next Generation
10.1016/j.cell.2011.02.013 · ExternalCitation · doi-reference
A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra
10.1016/j.celrep.2018.11.086 · ExternalCitation · doi-reference
The Controversial Relationship between Benign Prostatic Hyperplasia and Prostate Cancer: The Role of Inflammation
10.1016/j.eururo.2011.03.055 · ExternalCitation · doi-reference
Systematic Review of Complications of Prostate Biopsy
10.1016/j.eururo.2013.05.049 · ExternalCitation · doi-reference
Overdiagnosis and Overtreatment of Prostate Cancer
10.1016/j.eururo.2013.12.062 · ExternalCitation · doi-reference
Stromal Gene Expression Is Predictive for Metastatic Primary Prostate Cancer
10.1016/j.eururo.2017.02.038 · ExternalCitation · doi-reference
Conventional and PD‐L1‐expressing Regulatory T Cells Are Enriched during BCG Therapy and May Limit Its Efficacy
10.1016/j.eururo.2018.06.045 · ExternalCitation · doi-reference
Biopsy Criteria for Determining Appropriateness for Active Surveillance in the Modern Era
10.1016/j.urology.2013.12.054 · ExternalCitation · doi-reference
Identification of Prostate‐Enriched Proteins by In‐Depth Proteomic Analyses of Expressed Prostatic Secretions in Urine
10.1021/pr2011236 · ExternalCitation · doi-reference
CD90/THY1 Is Overexpressed in Prostate Cancer‐Associated Fibroblasts and Could Serve as a Cancer Biomarker
10.1038/modpathol.2010.122 · ExternalCitation · doi-reference
Identification of Stromally Expressed Molecules in the Prostate by Tag‐Profiling of Cancer‐Associated Fibroblasts, Normal Fibroblasts and Fetal Prostate
10.1038/onc.2011.312 · ExternalCitation · doi-reference
Stromal and Epithelial Transcriptional Map of Initiation Progression and Metastatic Potential of Human Prostate Cancer
10.1038/s41467-017-00460-4 · ExternalCitation · doi-reference
Spatial Maps of Prostate Cancer Transcriptomes Reveal an Unexplored Landscape of Heterogeneity
10.1038/s41467-018-04724-5 · ExternalCitation · doi-reference
Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes
10.1038/s41467-024-49424-5 · ExternalCitation · doi-reference
Integrative Metabolic and Transcriptomic Profiling of Prostate Cancer Tissue Containing Reactive Stroma
10.1038/s41598-018-32549-1 · ExternalCitation · doi-reference
The Relationship between T‐Lymphocyte Subset Infiltration and Survival in Patients with Prostate Cancer
10.1038/sj.bjc.6601943 · ExternalCitation · doi-reference
In Silico Dissection of Cell‐Type‐Associated Patterns of Gene Expression in Prostate Cancer
10.1073/pnas.2536479100 · ExternalCitation · doi-reference
Unravelling the Proteomic Landscape of Extracellular Vesicles in Prostate Cancer by Density‐Based Fractionation of Urine
10.1080/20013078.2020.1736935 · ExternalCitation · doi-reference
The Sva Package for Removing Batch Effects and Other Unwanted Variation in High‐Throughput Experiments
10.1093/bioinformatics/bts034 · ExternalCitation · doi-reference
Adjusting Batch Effects in Microarray Expression Data Using Empirical Bayes Methods
10.1093/biostatistics/kxj037 · ExternalCitation · doi-reference
CellMarker 2.0: An Updated Database of Manually Curated Cell Markers in Human/Mouse and Web Tools Based on scRNA‐Seq Data
10.1093/nar/gkac947 · ExternalCitation · doi-reference
Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer
10.1097/ju.0000000000001066 · ExternalCitation · doi-reference
Hematuria Following Post‐Prostatectomy Radiotherapy: Incidence Increases with Long‐Term Followup
10.1097/ju.0000000000002443 · ExternalCitation · doi-reference
Multimodal Biomarkers that Predict the Presence of Gleason Pattern 4: Potential Impact for Active Surveillance
10.1097/ju.0000000000003507 · ExternalCitation · doi-reference
Cellular Constituents of the Prostate Stroma: Key Contributors to Prostate Cancer Progression and Therapy Resistance
10.1101/cshperspect.a030510 · ExternalCitation · doi-reference
Standardization of Gleason Grading among 337 European Pathologists
10.1111/his.12008 · ExternalCitation · doi-reference
Gross Hematuria in Patients with Prostate Cancer: Etiology and Management
10.1155/2013/685327 · ExternalCitation · doi-reference
SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor
10.1158/1078-0432.ccr-14-3308 · ExternalCitation · doi-reference
Identification of a Candidate Gene Panel for the Early Diagnosis of Prostate Cancer
10.1158/1078-0432.ccr-14-3334 · ExternalCitation · doi-reference
Development and Preliminary Clinical Application of Circulating Tumor Cell Detection System for Prostate Cancer
10.1166/jbn.2019.2706 · ExternalCitation · doi-reference
Immunohistochemical Localization of Zn‐Alpha 2‐glycoprotein in Normal Human Tissues
10.1177/39.9.1918940 · ExternalCitation · doi-reference
Prognostic Value of Inflammation in Prostate Cancer Progression and Response to Therapeutic: A Critical Review
10.1186/s12950-016-0143-2 · ExternalCitation · doi-reference
Analytical Validation of an mRNA‐Based Urine Test to Predict the Presence of High‐Grade Prostate Cancer
10.1186/s41231-017-0014-8 · ExternalCitation · doi-reference
The Comprehensive Role of E‐Cadherin in Maintaining Prostatic Epithelial Integrity during Oncogenic Transformation and Tumor Progression
10.1371/journal.pgen.1008451 · ExternalCitation · doi-reference
Expression Changes in the Stroma of Prostate Cancer Predict Subsequent Relapse
10.1371/journal.pone.0041371 · ExternalCitation · doi-reference
Distribution of 15 Human Kallikreins in Tissues and Biological Fluids
10.1373/clinchem.2007.088104 · ExternalCitation · doi-reference
TMPRSS2‐ERG Fusion Transcripts in Matched Urine and Needle Rinse Material After Biopsy for the Detection of Prostate Cancer
10.1373/clinchem.2012.192260 · ExternalCitation · doi-reference
Identification of Prostate Cancer Biomarkers in Urinary Exosomes
10.18632/oncotarget.4851 · ExternalCitation · doi-reference
Comprehensive Analysis of RNA Expression Correlations between Biofluids and Human Tissues
10.3390/genes12060935 · ExternalCitation · doi-reference
Roles of Regulatory T Cell‐Derived Extracellular Vesicles in Human Diseases
10.3390/ijms231911206 · ExternalCitation · doi-reference
Integrated Urinary and Tissue Proteomic Signatures Reveal Core and Progression Biomarkers in MRI‐Visible and MRI‐Non‐Visible Prostate Cancer
10.3390/life16030383 · ExternalCitation · doi-reference
CD4+CD25high T Cells Are Enriched in the Tumor and Peripheral Blood of Prostate Cancer Patients
10.4049/jimmunol.177.10.7398 · ExternalCitation · doi-reference
