Research graph
References from Information‐Theoretic Framework for Allosteric Communication Pathway Prediction From Protein Structure. Local targets link to admitted publications; unresolved targets remain external evidence.
The Ensemble Nature of Allostery
10.1038/nature13001 · 2014 · External reference
An Ensemble View of Allostery
10.1126/science.1186121 · 2010 · External reference
Protein Allostery and Conformational Dynamics
10.1021/acs.chemrev.5b00590 · 2016 · External reference
Global Dynamics of Proteins: Bridging Between Structure and Function
10.1146/annurev.biophys.093008.131258 · 2010 · External reference
Bridging Protein Structure, Dynamics, and Function Using Hydrogen/Deuterium‐Exchange Mass Spectrometry
10.1002/pro.3790 · 2020 · External reference
Double Mutant Cycles as a Tool to Address Folding, Binding, and Allostery
10.3390/ijms22020828 · 2021 · External reference
Solution NMR Spectroscopy for the Study of Enzyme Allostery
10.1021/acs.chemrev.5b00541 · 2016 · External reference
Detection of Allosteric Signal Transmission by Information‐Theoretic Analysis of Protein Dynamics
10.1016/j.bpj.2011.11.1237 · 2012 · External reference
Exploring Residue Component Contributions to Dynamical Network Models of Allostery
10.1021/ct300377a · 2012 · External reference
Molecular Dynamics Simulations Provide Further Insights Into the Allosteric Regulation of the Kinesin‐5 Motor Domain by Loop 5
10.1021/acs.jcim.5c02999 · 2026 · External reference
Unresolved reference
2009 · External reference
Causality, Transfer Entropy, and Allosteric Communication Landscapes in Proteins With Harmonic Interactions
10.1002/prot.25272 · 2017 · External reference
Transfer Entropy and Protein Allostery: Promise, Limits, and Applications
10.1016/j.bpj.2021.11.2049 · 2022 · External reference
Signal Propagation in Proteins and Relation to Equilibrium Fluctuations
10.1371/journal.pcbi.0030172 · 2007 · External reference
Computational Analysis of Long‐Range Allosteric Communications in CFTR
10.7554/elife.88659.3 · 2023 · External reference
Distinct Allosteric Networks Underlie Mechanistic Speciation of ABC Transporters
10.1016/j.str.2020.03.014 · 2020 · External reference
Calculating Transfer Entropy From Variance–Covariance Matrices Provides Insight Into Allosteric Communication in ERK2
10.1021/acs.jctc.1c00004 · 2021 · External reference
Measuring Information Transfer
10.1103/physrevlett.85.461 · 2000 · External reference
10.1073/pnas.0904492106
10.1073/pnas.0904492106 · External reference
MCPath: Monte Carlo Path Generation Approach to Predict Likely Allosteric Pathways and Functional Residues
10.1093/nar/gkt284 · 2013 · External reference
10.21203/rs.3.rs-8958159/v1
10.21203/rs.3.rs-8958159/v1 · External reference
Kinesin‐5 Allosteric Inhibitors Uncouple the Dynamics of Nucleotide, Microtubule, and Neck‐Linker Binding Sites
10.1016/j.bpj.2014.09.019 · 2014 · External reference
Crystal Structures of a Complexed and Peptide‐Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
10.1016/s0092-8674(00)81307-0 · 1996 · External reference
Crystal Structure of p38 Mitogen‐Activated Protein Kinase
10.1074/jbc.271.44.27696 · 1996 · External reference
Structure‐Based Development of New RAS‐Effector Inhibitors From a Combination of Active and Inactive RAS‐Binding Compounds
10.1073/pnas.1811360116 · 2019 · External reference
ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two‐Water Mechanism
10.1016/j.bpj.2009.12.3344 · 2010 · External reference
Crystal Structure of the Mitotic Spindle Kinesin Eg5 Reveals a Novel Conformation of the Neck‐Linker
10.1074/jbc.m100395200 · 2001 · External reference
Functional Interplay Between Protein Domains in a Supramodular Structure Involving the Postsynaptic Density Protein PSD‐95
10.1074/jbc.ra119.011050 · 2020 · External reference
Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I
10.1074/jbc.m111.242362 · 2011 · External reference
Peptide Binding to the PDZ3 Domain by Conformational Selection
10.1002/prot.24137 · 2012 · External reference
Phosphorylation of a PDZ Domain Extension Modulates Binding Affinity and Interdomain Interactions in Postsynaptic Density‐95 (PSD‐95) Protein, a Membrane‐Associated Guanylate Kinase (MAGUK)
10.1074/jbc.m111.272583 · 2011 · External reference
An Overview of Mammalian p38 Mitogen‐Activated Protein Kinases, Central Regulators of Cell Stress and Receptor Signaling
2020 · External reference
p38MAPK: Stress Responses From Molecular Mechanisms to Therapeutics
10.1016/j.molmed.2009.06.005 · 2009 · External reference
p38α MAP Kinase C‐Terminal Domain Binding Pocket Characterized by Crystallographic and Computational Analyses
10.1016/j.jmb.2009.06.005 · 2009 · External reference
KRAS Mutation: From Undruggable to Druggable in Cancer
10.1038/s41392-021-00780-4 · 2021 · External reference
Targeting KRAS G12D: Advances in Inhibitor Design
10.1111/1759-7714.70203 · 2025 · External reference
G12 Mutations Rewire Allosteric Communication at the Ras–RalGDS Interface
10.1016/j.bpj.2026.01.053 · 2026 · External reference
Oncogenic G12D Mutation Alters Local Conformations and Dynamics of K‐Ras
10.1038/s41598-019-48029-z · 2019 · External reference
Assessment of Mutation Probabilities of KRAS G12 Missense Mutants and Their Long‐Timescale Dynamics by Atomistic Molecular Simulations and Markov State Modeling
10.1371/journal.pcbi.1006458 · 2018 · External reference
Insight Into Structural Dynamics Involved in Activation Mechanism of Full Length KRAS Wild Type and P‐Loop Mutants
10.1016/j.heliyon.2024.e36161 · 2024 · External reference
Identifying Causality in Mutant KRas Residue Pairs From Molecular Dynamics Data Analysis
10.1016/j.bpj.2017.11.2199 · 2018 · External reference
Intrinsic K‐Ras Dynamics: A Novel Molecular Dynamics Data Analysis Method Shows Causality Between Residue Pair Motions
10.1038/srep37012 · 2016 · External reference
Decrypting Allostery in Membrane‐Bound K‐Ras4B Using Complementary in Silico Approaches Based on Unbiased Molecular Dynamics Simulations
10.1021/jacs.3c11396 · 2023 · External reference
The Energetic and Allosteric Landscape for KRAS Inhibition
10.1038/s41586-023-06954-0 · 2024 · External reference
Novel Allosteric Sites on Ras for Lead Generation
10.1371/journal.pone.0025711 · 2011 · External reference
Oncogenic and RASopathy‐Associated K‐RAS Mutations Relieve Membrane‐Dependent Occlusion of the Effector‐Binding Site
10.1073/pnas.1419895112 · 2015 · External reference
Probing the Conformational and Energy Landscapes of KRAS Membrane Orientation
10.1021/acs.jpcb.9b05796 · 2019 · External reference
The Bipolar Mitotic Kinesin Eg5 Moves on Both Microtubules That It Crosslinks
10.1038/nature03503 · 2005 · External reference
Kinesin‐5: Cross‐Bridging Mechanism to Targeted Clinical Therapy
10.1016/j.gene.2013.08.004 · 2013 · External reference
