Research graph
References from Physical activity and combinations with modifiable factors and risk of cognitive impairment: the Whitehall II study. Local targets link to admitted publications; unresolved targets remain external evidence.
Physical activity as a protective factor for dementia and Alzheimer's disease: systematic review, meta‐analysis and quality assessment of cohort and case–control studies
10.1136/bjsports-2021-104981 · 2022 · External reference
Effect of a 24‐Month Physical Activity Intervention vs Health Education on Cognitive Outcomes in Sedentary Older Adults: The LIFE Randomized Trial
10.1001/jama.2015.9617 · 2015 · External reference
The age‐dependent relation of blood pressure to cognitive function and dementia
10.1016/s1474-4422(05)70141-1 · 2005 · External reference
Midlife and late‐life obesity and the risk of dementia: cardiovascular health study
10.1001/archneurol.2008.582 · 2009 · External reference
Serum cholesterol changes after midlife and late‐life cognition: twenty‐one‐year follow‐up study
10.1212/01.wnl.0000256368.57375.b7 · 2007 · External reference
Diabetes in midlife and cognitive change over 20 years: a cohort study
10.7326/m14-0737 · 2014 · External reference
Smoking is associated with an increased risk of dementia: a meta‐analysis of prospective cohort studies with investigation of potential effect modifiers
10.1371/journal.pone.0118333 · 2015 · External reference
MIND diet slows cognitive decline with aging
10.1016/j.jalz.2015.04.011 · 2015 · External reference
MIND not Mediterranean diet related to 12‐year incidence of cognitive impairment in an Australian longitudinal cohort study
10.1016/j.jalz.2018.12.011 · 2019 · External reference
MIND diet associated with reduced incidence of Alzheimer's disease
10.1016/j.jalz.2014.11.009 · 2015 · External reference
Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission
10.1016/s0140-6736(24)01296-0 · 2024 · External reference
Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons
10.1056/nejmoa2302368 · 2023 · External reference
Target Trial Emulation: A Framework for Causal Inference From Observational Data
10.1001/jama.2022.21383 · 2022 · External reference
Dementia and cognitive impairment: epidemiology, diagnosis, and treatment
10.1016/j.cger.2014.04.001 · 2014 · External reference
Cohort Profile: the Whitehall II study
10.1093/ije/dyh372 · 2005 · External reference
Comprehensive evaluation of the Minnesota Leisure Time Physical Activity Questionnaire
10.1016/0895-4356(94)90008-6 · 1994 · External reference
2011 Compendium of Physical Activities: a second update of codes and MET values
10.1249/mss.0b013e31821ece12 · 2011 · External reference
Physical activity, cognitive decline, and risk of dementia: 28 year follow‐up of Whitehall II cohort study
10.1136/bmj.j2709 · 2017 · External reference
Association between questionnaire‐ and accelerometer‐assessed physical activity: the role of sociodemographic factors
10.1093/aje/kwt330 · 2014 · External reference
Dietary pattern, inflammation and cognitive decline: The Whitehall II prospective cohort study
10.1016/j.clnu.2016.01.013 · 2017 · External reference
Reproducibility and validity of a semiquantitative food frequency questionnaire
10.1093/oxfordjournals.aje.a114086 · 1985 · External reference
Validation of dietary assessment methods in the UK arm of EPIC using weighed records, and 24‐hour urinary nitrogen and potassium and serum vitamin C and carotenoids as biomarkers
10.1093/ije/26.suppl_1.s137 · 1997 · External reference
Dietary assessment in Whitehall II: comparison of 7 d diet diary and food‐frequency questionnaire and validity against biomarkers
10.1079/bjn2001414 · 2001 · External reference
Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension
10.1093/eurheartj/ehy288 · 2018 · External reference
Obesity trajectories and risk of dementia: 28 years of follow‐up in the Whitehall II Study
10.1016/j.jalz.2017.06.2637 · 2018 · External reference
Timing of onset of cognitive decline: results from Whitehall II prospective cohort study
10.1136/bmj.d7622 · 2012 · External reference
Body mass index over the adult life course and cognition in late midlife: the Whitehall II Cohort Study
10.3945/ajcn.2008.26482 · 2009 · External reference
Unresolved reference
1970 · External reference
Word fluency and brain damage
10.1016/0028-3932(67)90015-2 · 1967 · External reference
Unresolved reference
1958 · External reference
Longitudinal Standards for Mid‐life Cognitive Performance: Identifying Abnormal Within‐Person Changes in the Wisconsin Registry for Alzheimer's Prevention
10.1017/s1355617718000929 · 2019 · External reference
10.1002/0470846410.ch27(ii)
10.1002/0470846410.ch27(ii) · 2002 · External reference
Physical activity initiated from midlife on risk of dementia and cognitive impairment: The Health and Retirement Study
10.1111/jgs.19109 · 2024 · External reference
Effects of exercise training on the cognitive function of older adults with different types of dementia: a systematic review and meta‐analysis
10.1136/bjsports-2021-104955 · 2022 · External reference
view and meta‐meta‐analysis
2025 · External reference
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at‐risk elderly people (FINGER): a randomised controlled trial
10.1016/s0140-6736(15)60461-5 · 2015 · External reference
Structured vs Self‐Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial
10.1001/jama.2025.12923 · 2025 · External reference
An online multidomain lifestyle intervention to prevent cognitive decline in at‐risk older adults: a randomized controlled trial
10.1038/s41591-024-03351-6 · 2025 · External reference
A multidomain intervention against cognitive decline in an at‐risk‐population in Germany: Results from the cluster‐randomized AgeWell.de trial
10.1002/alz.13486 · 2024 · External reference
Effect of long‐term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo‐controlled trial
10.1016/s1474-4422(17)30040-6 · 2017 · External reference
Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial
10.1016/s2589-7500(19)30153-0 · 2019 · External reference
Dementia prevention: The potential long‐term cost‐effectiveness of the FINGER prevention program
10.1002/alz.12698 · 2023 · External reference
The Effects of Social Interaction Intervention on Cognitive Functions Among Older Adults Without Dementia: A Systematic Review and Meta‐Analysis
10.1093/geroni/igae084 · 2024 · External reference
Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions
10.1001/jama.2019.10551 · 2019 · External reference
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging
10.1016/s1474-4422(13)70060-7 · 2013 · External reference
Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia
2012 · External reference
The anti‐inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
10.1038/nri3041 · 2011 · External reference
Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment
10.2174/156720507780362137 · 2007 · External reference
Cost‐Effectiveness of Prevention for People at Risk for Dementia: A Scoping Review and Qualitative Synthesis
10.14283/jpad.2024.12 · 2024 · External reference
Association between questionnaire‐ and accelerometer‐assessed physical activity: the role of sociodemographic factors
10.1093/aje/kwt330 · 2014 · External reference