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References from Intrathymic Expression of Genes Involved in Organ Specific Autoimmune Disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Cellular interactions in thymocyte development
10.1146/annurev.immunol.14.1.73 · 1996 · External reference
A nondeletional mechanism of thymic self tolerance
10.1126/science.2511629 · 1989 · External reference
Strong T cell tolerance in parent-F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy
10.1084/jem.171.4.1101 · 1990 · External reference
Tolerance induction by thymic medullary epithelium
10.1073/pnas.89.7.2526 · 1992 · External reference
Anergy induced by thymic medullary epithelium
10.1002/eji.1830220704 · 1992 · External reference
Immunological function of a defined T-cell population tolerized to low-affinity self antigens
10.1038/374068a0 · 1995 · External reference
CD4 cell tolerance to nuclear proteins induced by medullary thymic epithelium
10.1016/s1074-7613(00)80481-1 · 1996 · External reference
Lymphocytes selected in allogeneic thymic epithelium mediate dominant tolerance toward tissue grafts of the thymic epithelium haplotype
10.1073/pnas.92.16.7555 · 1995 · External reference
Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells
10.1111/j.1600-065x.1996.tb00898.x · 1996 · External reference
The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset
10.1111/j.1600-065x.1996.tb00905.x · 1996 · External reference
Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy
10.1146/annurev.iy.07.040189.002305 · 1989 · External reference
Ablation of ‘tolerance’ and induction of diabetes by virus infection in viral antigen transgenic mice
10.1016/0092-8674(91)90164-t · 1991 · External reference
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity
10.1016/0092-8674(90)90420-j · 1990 · External reference
T-cell tolerance toward a transgenic beta cell antigen and transcription of endogenous pancreatic genes in thymus
10.1073/pnas.91.14.6707 · 1994 · External reference
Autoimmune diabetes as a consequence of locally produced interleukin-2
10.1038/359547a0 · 1992 · External reference
Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters
10.1093/intimm/6.2.277 · 1994 · External reference
Mechanisms of immune tolerance induction through the thymic expression of a peripheral tissue-specific protein
10.1093/intimm/7.5.715 · 1995 · External reference
A novel transcript overlapping the myelin basic protein gene
10.1111/j.1471-4159.1992.tb10126.x · 1992 · External reference
Identification of an embryonic isoform of myelin basic protein that is expressed widely in the mouse embryo
10.1073/pnas.90.21.10125 · 1993 · External reference
The human myelin basic protein gene is included within a 179-kilobase transcription unit: expression in the immune and central nervous systems
10.1073/pnas.90.22.10695 · 1993 · External reference
The shaping of the brain-specific T lymphocyte repertoire in the thymus
10.1111/j.1600-065x.1996.tb00907.x · 1996 · External reference
Autoimmune thyroid disease: developments in our understanding
10.1210/edrv-5-2-309 · 1984 · External reference
Myelin basic protein and proteolipid protein reactivity of brain- and cerebrospinal fluid-derived T cell clones in multiple sclerosis and postinfectious encephalomyelitis
10.4049/jimmunol.139.1.68 · 1987 · External reference
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
10.1002/eji.1830240820 · 1994 · External reference
Thyroid peroxidase is the organ-specific ‘microsomal’ autoantigen involved in thyroid autoimmunity
1987 · External reference
The nucleotide sequence of the rat cytoplasmic beta-actin gene
10.1093/nar/11.6.1759 · 1983 · External reference
The structure and evolution of the two nonallelic rat preproinsulin genes
10.1016/0092-8674(79)90071-0 · 1979 · External reference
Characterization of the two nonallelic genes encoding mouse preproinsulin
10.1007/bf02100639 · 1986 · External reference
Characterization of cloned cDNA representing rat myelin basic protein: absence of expression in brain of shiverer mutant mice
10.1016/0092-8674(83)90536-6 · 1983 · External reference
The sequence of 967 amino acids at the carboxyl-end of rat thyroglobulin. Location and surroundings of two thyroxine-forming sites
10.1111/j.1432-1033.1985.tb08799.x · 1985 · External reference
Complete nucleotide sequence of the cDNA for thyroid peroxidase in FRTL5 rat thyroid cells
10.1093/nar/17.20.8380 · 1989 · External reference
MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus
10.1038/362070a0 · 1993 · External reference
Differential expression of Mtv loci in MHC class II-positive thymic stromal cells
10.4049/jimmunol.152.10.4826 · 1994 · External reference
Studies on T cell maturation on defined thymic stromal cell populationsin vitro
10.1084/jem.176.3.845 · 1992 · External reference
Characteristics of anin vitro
10.4049/jimmunol.153.5.1915 · 1994 · External reference
Stimulation of thymocytes before and after positive selection results in the induction of different NF-kappa B/Rel protein complexes
10.4049/jimmunol.155.10.4653 · 1995 · External reference
Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction
10.1002/eji.1830230424 · 1993 · External reference
Molecular Cloning
1989 · External reference
Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway
10.1084/jem.173.1.79 · 1991 · External reference
Insulin gene expression and insulin synthesis in mammalian neuronal cells
10.1016/s0021-9258(17)37214-9 · 1994 · External reference
Structure and developmental regulation of Golli-mbp, a 105-kilobase gene that encompasses the myelin basic protein gene and is expressed in cells in the oligodendrocyte lineage in the brain
10.1016/s0021-9258(18)53485-2 · 1993 · External reference
A new family of transcripts of the myelin basic protein gene: expression in brain and in immune system
10.1111/j.1471-4159.1993.tb03325.x · 1993 · External reference
Thymic expression of myelin basic protein (MPB) Activation of MBP-specific T cells by thymic cells in the absence of exogenous MBP
10.4049/jimmunol.157.12.5249 · 1996 · External reference
Mammalian endogenous peroxidases as cellular markers and as biosynthetic endpoints of hormone-mediated activity: viewpoint from cytochemistry
1979 · External reference
Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance
10.1093/intimm/9.9.1355 · 1997 · External reference
RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon
1985 · External reference
Long interspersed repeated DNA (LINE) causes polymorphism at the rat insulin 1 locus
1985 · External reference
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
10.1002/eji.1830250430 · 1995 · External reference
Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities
10.1084/jem.171.3.935 · 1990 · External reference
Clonal deletion induced by either radioresistant thymic host cells or lymphohemopoietic donor cells at different stages of class I-restricted T cell ontogeny
10.1084/jem.175.5.1277 · 1992 · External reference
Clonal deletion of V beta 5+ T cells by transgenic I-E restricted to thymic medullary epithelium
10.4049/jimmunol.151.8.3954 · 1993 · External reference
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
10.1038/383081a0 · 1996 · External reference
Regulatory T cells in thymic epithelium-induced tolerance. I. Suppression of mature peripheral non-tolerant T. cells
10.1002/eji.1830250924 · 1995 · External reference
The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients
10.1084/jem.184.6.2393 · 1996 · External reference
Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction
10.4049/jimmunol.151.8.4098 · 1993 · External reference
Immunological consequences of T cell-specific expression of H-2Kb
10.1093/intimm/5.2.189 · 1993 · External reference
T cell tolerance by clonal elimination in the thymus
10.1016/0092-8674(87)90568-x · 1987 · External reference
How virus induces a rapid or slow onset insulin- dependent diabetes mellitus in a transgenic model
10.1016/1074-7613(94)90101-5 · 1994 · External reference
The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription
10.1038/ng0395-293 · 1995 · External reference
Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus
10.1038/ng0397-289 · 1997 · External reference
Thymic expression of autoantigen correlates with resistance to autoimmune disease
10.4049/jimmunol.159.7.3109 · 1997 · External reference
