Research graph
References from Endothelial Activation by aPL: A Potential Pathogenetic Mechanism for the Clinical Manifestations of the Syndrome. Local targets link to admitted publications; unresolved targets remain external evidence.
Immunology of the antiphospholipid antibody syndrome
10.1002/art.1780390903 · 1996 · External reference
Beta2-glycoprotein
10.1177/096120339400300401 · 1994 · External reference
Beta2-glycoprotein I as a ‘co-factor’ for anti-phospholipid reactivity with endothelial cells
10.1177/096120339800700211 · 1998 · External reference
Antiphospholipid antibodies affect trophoblast gonadotrophin secretion and invasiveness by binding directly and through adhered β2-glycoprotein I
10.1002/1529-0131(200001)43:1<140::aid-anr18>3.0.co;2-p · 2000 · External reference
Immune recognition at the maternal-fetal interface: overview
10.1111/j.1600-0897.1992.tb00773.x · 1992 · External reference
β2-glycoprotein I and placental anti-coagulant protein I in placentae from patients with anti-phospholipid syndrome
1994 · External reference
Relationship between anti-phospholipid and anti-endothelial antibodies III: β2-glycoprotein I mediates the antibody binding to endothelial membranes and induces the expression of adhesion molecules
1995 · External reference
Role of β2-glycoprotein I in the anti-phospholipid antibody binding to endothelial cells
10.1177/096120339500400304 · 1995 · External reference
Activation of cultured vascular endothelial cells by antiphospholipid antibodies
10.1172/jci118276 · 1995 · External reference
Endothelial cell as target for antiphospholipid antibodies
1997 · External reference
Differential effects of anti-beta 2 glycoprotein I antibodies on endothelial cells and on the manifestations of experimental antiphospholipid syndrome
10.1161/01.cir.97.9.900 · 1998 · External reference
Human β2-glycoprotein I binds to endothelial cells through a cluster of lysine residues that are critical for anionic phospholipid binding and offers epitopes for anti-β2glycoprotein I antibodies
10.4049/jimmunol.160.11.5572 · 1998 · External reference
Human β2-GPI binds to trophoblast through its fifth domain affecting human chorionic gonadotrophin release
2000 · External reference
Anti-phospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
10.1161/01.cir.99.15.1997 · 1999 · External reference
Antigenic heterogeneity of vascular endothelium
1992 · External reference
Vascular-Bed Specific hemostasis and hypercoagulable states
10.1056/nejm199905203402007 · 1990 · External reference
aPL reactivity with human brain microvascular endothelial cells (BEC)
2000 · External reference
Beta2-glycoprotein I (beta2-GPI) mRNA is expressed by several cell types involved in anti-phospholipid syndrome-related tissue damage
10.1046/j.1365-2249.1999.00770.x · 1999 · External reference
Increased soluble vascular adhesion molecule 1 concentrations in patients with primary or systemic lupus-erythematosus syndrome: correlations with the severity of thrombosis
10.1002/1529-0131(200001)43:1<55::aid-anr8>3.0.co;2-m · 2000 · External reference
The anti-phospholipid (Hughes) syndrome: a crossroads of autoimmunity and atherosclerosis
10.1177/096120339700600701 · 1997 · External reference
Atherosclerosis in SLE and Hughes syndrome
10.1177/096120339700600601 · 1997 · External reference
Molecular basis of the acute coronary syndromes
10.1161/01.cir.91.11.2844 · 1995 · External reference
Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent
10.1073/pnas.77.7.3957 · 1980 · External reference
HMG-CoA reductase inhibitors for treatment of hypercholesterolemia
10.1056/nejm198807073190105 · 1988 · External reference
Tissue selectivity of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase inhibitors
10.1016/0163-7258(93)90031-8 · 1993 · External reference
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase
10.1016/0021-9150(93)90107-6 · 1993 · External reference
HMG CoA reductase inhibitors. In vivo effects on carotid intimal thickening in normocholesterolemic rabbits
10.1161/01.atv.13.4.571 · 1993 · External reference
Vastatin inhibit cholesterol ester accumulation in human monocyte-derived macrophages
10.1161/01.atv.11.1.146 · 1991 · External reference
HMGCoA reductase inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages
10.1161/01.atv.15.9.1352 · 1995 · External reference
Chemotaxis of the monocyte cell line U937: dependence on cholesterol and early mevalonate pathway products
10.1016/0021-9150(91)90116-k · 1991 · External reference
Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells
10.1002/jlb.55.6.749 · 1994 · External reference
Reduced platelet aggregation after fluvastatin therapy is associated with altered platelet lipid composition and drug binding to the platelets
10.1046/j.1365-2125.1997.00625.x · 1997 · External reference
Interactions of platelets, macrophages, and lipoproteins in hypercholesterolemia: antiatherogenic effects of HMG-CoA reductase inhibitor therapy
10.1097/00005344-199801000-00006 · 1998 · External reference
Vastatin inhibit tissue factor in cultured human macrophages: a novel mechanism of protection against atherothrombosis
10.1161/01.atv.17.2.265 · 1997 · External reference
Hyperlipidemia and coronary disease: correction of the increased thrombogenic potential with cholesterol reduction
10.1161/01.cir.92.11.3172 · 1995 · External reference
Endothelial cells in physiology and in the pathophysiology of vascular disorders
1998 · External reference
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitrix oxide synthase in vascular endothelial cells
10.1172/jci1500 · 1998 · External reference
Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors
10.1161/01.cir.97.12.1129 · 1998 · External reference
3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors increase fibrinolytic activity in rat aortic endothelial cells. Role of geranylgeranylation and Rho proteins
10.1161/01.res.83.7.683 · 1998 · External reference
Antiendothelial cell IgG fractions from systemic lupus erythematosus patients bind to human endothelial cells and induce a pro-adhesive and a pro-inflammatory phenotype in vitro
1999 · External reference
Murine models of systemic lupus erythematosus
10.1016/s0065-2776(08)60342-9 · 1985 · External reference
