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References from Has GAD a Central Role in Type 1 Diabetes?. Local targets link to admitted publications; unresolved targets remain external evidence.
Immune phenomena and events in the islets in insulin-dependent diabetes mellitus
1997 · External reference
Insulin-dependent diabetes mellitus
1998 · External reference
Immunopathogenesis of diabetes mellitus
1993 · External reference
The pathogenesis of insulin-dependent diabetes mellitus
10.1056/nejm199411243312107 · 1994 · External reference
Insulin-dependent diabetes mellitus as a β cell targeted disease of immunoregulation
10.1016/0896-8411(95)90001-2 · 1995 · External reference
Prediction of type I diabetes: the natural history of the prediabetic period
1996 · External reference
Insulin-dependent diabetes mellitus
10.1016/s0092-8674(00)81106-x · 1996 · External reference
The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD
10.1016/s1074-7613(00)80392-1 · 1997 · External reference
Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM: Therapeutic intervention by immunostimulation?
10.2337/diab.43.5.613 · 1994 · External reference
Genetic and pathogenic basis of autoimmune diabetes in NOD mice
10.1016/0952-7915(94)90011-6 · 1994 · External reference
Immunology in diabetes: an update
10.1002/(sici)1099-0895(199803)14:1<3::aid-dmr206>3.0.co;2-t · 1998 · External reference
Mechanisms of pancreatic beta cell destruction in type I diabetes
1988 · External reference
The role of CD4+and CD8+T cells in Type 1 diabetes in the NOD mouse
10.1016/s0923-2494(97)87242-2 · 1997 · External reference
Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
10.1016/s0140-6736(74)90140-8 · 1974 · External reference
Antibodies to pancreatic islet cells in insulin-dependent diabetics with coexistent autoimmune disease
10.1016/s0140-6736(74)90281-5 · 1974 · External reference
Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes
10.1016/0140-6736(90)90013-u · 1990 · External reference
Islet cell autoantigens in insulin-dependent diabetes
10.1172/jci116745 · 1993 · External reference
Autoantibodies in newly diagnosed diabeic children immunoprecipitate specific human islet cell proteins
10.1038/298167a0 · 1992 · External reference
Antibodies to a 64,000Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes
10.1172/jci112903 · 1987 · External reference
64,000Mr autoantibodies as predictors of insulin-dependent diabetes
10.1016/0140-6736(90)91241-2 · 1990 · External reference
Autoantibodies to a 64-kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat
10.1126/science.6374896 · 1984 · External reference
Autoantibodies in nonobese diabetic mice immunoprecipitate 64,000-Mr islet antigen
10.2337/diab.37.11.1587 · 1988 · External reference
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase
10.1038/347151a0 · 1990 · External reference
Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus
10.1056/nejm198804213181602 · 1988 · External reference
Autoantibodies to GABA-ergic neurons and pancreatic beta cells in stiff-man syndrome
10.1056/nejm199005313222202 · 1990 · External reference
Two genes encode distinct glutamate decarboxylases
10.1016/0896-6273(91)90077-d · 1991 · External reference
Gamma-aminobutyric acid outside the mammalian brain
10.1111/j.1471-4159.1990.tb01882.x · 1990 · External reference
Glutamate decarboxylase in nonneural cells of rat testis and oviduct: differential expression of GAD65and GAD67
10.1111/j.1471-4159.1992.tb09763.x · 1992 · External reference
Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat
10.1210/endo.133.6.8243324 · 1993 · External reference
Differential expression of glutamic acid decarboxylase in rat and human islets
10.2337/diab.42.3.484 · 1993 · External reference
Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets
10.2337/diab.42.12.1799 · 1993 · External reference
Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-M(r) autoantibodies
10.2337/diab.41.10.1355 · 1992 · External reference
Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus
10.1172/jci115573 · 1992 · External reference
Persistent GAD 65 antibodies in longstanding IDDM are not associated with residual beta-cell function, neuropathy or HLA-DR status
10.1055/s-2007-979091 · 1997 · External reference
Autoantibodies in IDDM primarily recognize the 65,000-M(r) rather than the 67,000-M(r) isoform of glutamic acid decarboxylase
10.2337/diab.42.4.631 · 1993 · External reference
Autoantibodies to glutamic acid decarboxylase in patients with IDDM and autoimmune thyroid disease
10.2337/diab.43.1.80 · 1994 · External reference
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
10.1038/366072a0 · 1993 · External reference
Response of peripheral blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes
10.1016/0140-6736(92)91061-c · 1992 · External reference
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients
10.1172/jci119423 · 1997 · External reference
Glutamic acid decarboxylase 67-reactive T cells: a maker of insulin-dependent diabetes
10.1084/jem.177.2.535 · 1993 · External reference
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
10.1084/jem.181.5.1923 · 1995 · External reference
Induction of insulitis by glutamic acid decarboxylase peptide-specific and CD4(+) T cells from human DQ transgenic mice
10.1172/jci2723 · 1998 · External reference
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
10.1038/366069a0 · 1993 · External reference
Role of Coxsackie B4 viruses in the pathogenesis of diabetes mellitus
1996 · External reference
Antibodies to glutamic acid decarboxylase and P2-C peptides in sera from Coxsackie virus B4-infected mice and IDDM patients
10.2337/diab.43.10.1260 · 1994 · External reference
Cellular immunity to a determinant common to glutamate decarboxylase and Coxsackie virus in insulin-dependent diabetes
10.1172/jci117567 · 1994 · External reference
Sequence homology of the diabetes-associated autoantigen glutamate decarboxylase with Coxsackie B4-2C protein and heat shock protein 60 mediates no molecular mimicry of autoantibodies
10.1084/jem.180.2.721 · 1994 · External reference
Immunodominant epitopes of glutamic acid decarboxylase 65 and 67 in insulin-dependent diabetes mellitus
10.1016/s0140-6736(94)93061-9 · 1994 · External reference
Epitopes of GAD65 in insulin-dependent diabetes mellitus
10.1016/s0140-6736(94)91432-x · 1994 · External reference
T cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects
10.1007/s001250050683 · 1997 · External reference
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients
10.1172/jci119423 · 1997 · External reference
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401
10.1172/jci119079 · 1996 · External reference
Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice
10.2337/diabetes.48.3.469 · 1999 · External reference
Immunization with the larger isoform of mouse glutamic acid decarboxylase (GAD67) prevents autoimmune diabetes in NOD mice
10.2337/diab.43.12.1494 · 1994 · External reference
Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance
10.1038/nm0797-793 · 1997 · External reference
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
10.1084/jem.183.4.1561 · 1996 · External reference
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice
10.1038/nm1296-1348 · 1996 · External reference
Retardation or acceleration of diabetes in NOD/Lt mice mediated by intrathymic administration of candidate beta-cell antigens
10.2337/diab.46.12.1975 · 1997 · External reference
GAD-reactive CD4+Th1 cells induce diabetes in NOD/SCID mice
10.1172/jci119878 · 1998 · External reference
Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells
10.1126/science.284.5417.1183 · 1999 · External reference
Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide
10.1006/jaut.1994.1048 · 1994 · External reference
Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice
10.2337/diab.43.12.1478 · 1994 · External reference
Peripheral T cell clones from NOD mice specific for GAD65 peptides: lack of islet responsiveness or diabetogenicity
10.1006/jaut.1996.0048 · 1996 · External reference
Glutamate decarboxylase and GABA in pancreatic islets: lessons from knock-out mice
10.1055/s-2007-978750 · 1999 · External reference
Control of autoimmune diabetes
10.1126/science.287.5451.191a · 2000 · External reference
