Research graph
References from It's Insulin. Local targets link to admitted publications; unresolved targets remain external evidence.
Insulin antibodies in insulin-dependent diabetics before insulin treatment
10.1126/science.6362005 · 1983 · External reference
Radioassay determination of insulin autoantibodies in NOD mice: correlation with increased risk of progression to overt diabetes
10.2337/diab.38.3.358 · 1989 · External reference
Establishment of islet-specific T-cell lines and clones from islet isografts placed in spontaneously diabetic NOD mice
10.1006/jaut.1993.1043 · 1993 · External reference
Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice
10.1002/eji.1830240820 · 1994 · External reference
Analysis of the spontaneous T cell response to insulin in NOD mice
10.1006/jaut.1994.1066 · 1994 · External reference
Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice
10.1002/eji.1830250430 · 1995 · External reference
Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
10.1073/pnas.93.2.956 · 1996 · External reference
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase
10.1038/347151a0 · 1990 · External reference
Islet cell autoantigens in insulin-dependent diabetes
10.1172/jci116745 · 1993 · External reference
The pathogenesis of insulin-dependent diabetes mellitus
10.1056/nejm199411243312107 · 1994 · External reference
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
10.1038/366072a0 · 1993 · External reference
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
10.1038/366069a0 · 1993 · External reference
GM2-1 pancreatic islet ganglioside: identification and characterization of a novel islet-specific molecule
10.1007/bf00402184 · 1995 · External reference
Cloning and expression of IDDM-specific human autoantigens
10.2337/diab.41.2.183 · 1992 · External reference
Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases
10.4049/jimmunol.152.6.3183 · 1994 · External reference
Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma
10.1089/dna.1994.13.505 · 1994 · External reference
Definition of multiple ICA512/phogrin autoantibody epitopes and detection of intramolecular epitope spreading in relatives of patients with type 1 diabetes
10.2337/diabetes.47.5.733 · 1998 · External reference
Protein tyrosine phosphatase-like proteins: link with IDDM
10.2337/diacare.20.2.208 · 1997 · External reference
Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes
10.1006/bbrc.1996.1526 · 1996 · External reference
Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2
10.2337/diab.45.10.1344 · 1996 · External reference
Molecular cloning of Phogrin, a protein-tyrosine phosphatase homologue localized to insulinsecretory granule membranes
10.1074/jbc.271.30.18161 · 1996 · External reference
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein
10.1073/pnas.87.4.1576 · 1990 · External reference
10.1073/pnas.88.8.3088
10.1073/pnas.88.8.3088 · 1991 · External reference
10.2337/diabetes.44.9.1132
10.2337/diabetes.44.9.1132 · External reference
The immune response to islets in experimental diabetes and insulin-dependent diabetes mellitus
10.1016/s0952-7915(96)80016-1 · 1996 · External reference
T-lymphocyte clone specific for pancreatic islet antigen
10.2337/diab.37.10.1444 · 1988 · External reference
Pancreatic islet-specific T-cell clones from nonobese diabetic mice
10.1073/pnas.86.20.8000 · 1989 · External reference
Acceleration of diabetes in young NOD Mice with a CD4+islet-specific T cell clone
10.1126/science.2205920 · 1990 · External reference
Nasal administation of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
10.1084/jem.183.4.1561 · 1996 · External reference
Insulitis and Diabetes in NOD Mice Reduced by Prophylactic Insulin Therapy
10.2337/diab.39.8.933 · 1990 · External reference
Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin
10.1073/pnas.88.22.10252 · 1991 · External reference
Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele. The IMDIAB Group
10.1038/ng1197-350 · 1997 · External reference
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
10.1038/ng0397-293 · 1997 · External reference
Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets
10.2337/diab.42.12.1799 · 1993 · External reference
Glutamate decarboxylase and GABA in pancreatic islets: lessons from knock-out mice
10.1055/s-2007-978750 · 1999 · External reference
Induction of GAD65-specific regulatory T-cells inhibits ongoing autoimmune diabetes in nonobese diabetic mice
10.2337/diabetes.47.6.894 · 1998 · External reference
Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice [published erratum appears in Diabetes 1997 46: 924]
10.2337/diab.46.1.34 · 1997 · External reference
Control of autoimmune diabetes in NOD mice by GAD expression or suppression in beta cells [see comments]
10.1126/science.284.5417.1183 · 1999 · External reference
Early expression of anti-insulin autoantibodies of man and the NOD mouse: evidence for early determination of subsequent diabetes
10.1073/pnas.040556697 · 2000 · External reference
Natural history of humoral immunity to glutamic acid decarboxylase in non-obese diabetic (NOD) mice
10.1006/jaut.1994.1049 · 1994 · External reference
Characterization of insulin autoantibodies in relatives of patients with Type I diabetes
10.2337/diab.42.8.1202 · 1993 · External reference
Prediction and prevention of type I diabetes
1994 · External reference
Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
10.2337/diab.45.7.926 · 1996 · External reference
Immunoglobulin G insulin autoantibodies in BABYDIAB offspring appear postnatally: sensitive early detection using a protein A/G-based radiobinding assay
1999 · External reference
Concentration of insulin autoantibodies at onset of type I diabetes. Inverse loglinear correlation with age
10.2337/diacare.11.9.736 · 1988 · External reference
Insulin autoimmunity: the rate limiting factor in pre-type-I diabetes
10.1016/0896-8411(92)90039-s · 1992 · External reference
Human T cell clones with specifcity for insulinoma cell antigens
10.1002/eji.1830190136 · 1989 · External reference
T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins
10.1038/345632a0 · 1990 · External reference
Autoimmune versus inflammatory type I diabetes: a controversy?
10.1016/0167-5699(95)80115-4 · 1995 · External reference
T-cell epitope analysis using subtracted expression libraries (TEASEL): Application to a 38kDa autoantigen recognized by T cells from an insulin-dependent diabetic patient
10.1073/pnas.93.5.2014 · 1996 · External reference
Autoreactive T cell Responses in Insulin-dependent (Type 1) Diabetes Mellitus. Report of the First International Workshop for Standardization of T cell assays
10.1006/jaut.1999.0312 · 1999 · External reference
Monoclonal T cells identifiied in early NOD islet infiltrates
1996 · External reference
Cloned T cells from a recent onset IDDM patient reactive with insulin B-chain
10.1006/jaut.1997.0183 · 1998 · External reference
