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References from IL-12 Enhances Lymphoaccumulation by Suppressing Cell Death of T Cells in MRL- Mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Fas and Fas ligand: lpr and gld mutations
10.1016/0167-5699(95)80069-7 · 1995 · External reference
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
10.1038/356314a0 · 1992 · External reference
Liver is a possible site for the proliferation of abnormal CD3+4−8−double negative lymphocytes in autoimmune MRL- lpr /lpr mice
10.1084/jem.172.1.7 · 1990 · External reference
MRL- lpr / lpr disease: theories meet Fas
10.1006/smim.1994.1009 · 1994 · External reference
Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte mutation factor)
10.4049/jimmunol.147.3.874 · 1991 · External reference
Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo
10.1093/intimm/6.1.157 · 1994 · External reference
Differential effects of IL-12 receptor blockade with IL-12p40 homodimer on the induction of CD4+ and CD8+ IFN-γ-producing cells
10.4049/jimmunol.158.2.643 · 1997 · External reference
Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection
10.1073/pnas.93.17.9085 · 1996 · External reference
Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo
10.1111/j.1749-6632.1996.tb52650.x · 1996 · External reference
A novel function of IL-12p40 as a chemotactic molecule for macrophages
10.4049/jimmunol.163.5.2902 · 1999 · External reference
TCR ligation on CD8+T cells creates double-negative cells in vivo
10.4049/jimmunol.161.4.1686 · 1998 · External reference
The abnormal T lymphocytes in lpr mice transcribe interferon-γ and tumor necrosis factor-α genes spontaneously in vivo
10.1002/eji.1830190325 · 1989 · External reference
Accelerated programmed cell death of MRL- lpr / lpr T lymphocytes
10.4049/jimmunol.149.7.2513 · 1992 · External reference
Intranasal immunization of a DNA vaccine with IL-12 and granulocyte-macrophage colony-stimulating factor (GM-CSF)-expressing plasmids in liposomes induces strong mucosal and cell-mediated immune responses against HIV-1 antigens
10.4049/jimmunol.159.7.3638 · 1997 · External reference
Efficient selection for high-expression transfectants with a novel eukaryotic vector
10.1016/0378-1119(91)90434-d · 1991 · External reference
10.4049/jimmunol.158.8.4008
10.4049/jimmunol.158.8.4008 · External reference
T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+T cells from human immunodeficiency virus-infected persons
10.1084/jem.182.6.1759 · 1995 · External reference
IL-12 inhibits apoptosis induced in a human Th1 clone by gp120/CD4 cross-linking and CD3/TCR activation or by IL-2 deprivation
10.1006/cimm.1995.1003 · 1995 · External reference
High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-β secretion and T cell apoptosis
10.4049/jimmunol.157.6.2348 · 1996 · External reference
Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice
10.1016/s0016-5085(99)70392-6 · 1999 · External reference
IL-12 in conjunction with dendritic cells enhances antiviral CD8+ CTL responses in vitro
10.1172/jci118843 · 1996 · External reference
The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL Mp- lpr / lpr mice
10.1084/jem.183.4.1447 · 1996 · External reference
Intrinsic defects in macrophage IL-12 production associated with immune dysfunction in the MRL/++ and New Zealand Black/White F1 lupus-prone mice and the Leishmania major-susceptible BALB/c strain
10.4049/jimmunol.161.12.6878 · 1998 · External reference
IFN-γ receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL- Fas(lpr) mice
10.4049/jimmunol.161.1.494 · 1998 · External reference
Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
10.1172/jci750 · 1998 · External reference
IFN-γ is essential for the development of autoimmune glomerulonephritis in MRL/lpr mice
10.4049/jimmunol.158.11.5484 · 1997 · External reference
Upregulation of lymphoid and renal interferon-γ mRNA in autoimmune MRL-Fas(lpr) mice with lupus nephritis
10.1023/a:1027399027170 · 1997 · External reference
