Research graph
References from Ribonucleases in evolution. Local targets link to admitted publications; unresolved targets remain external evidence.
Hydrogen exchange and proteolytic degradation of ribonuclease A. The local splitting of the native structure and the conformation of loop segments
10.1134/s0006350912010022 · 2012 · External reference
The brilliance of Borrelia: mechanisms of host immune evasion by lyme disease-causing spirochetes
10.3390/pathogens10030281 · 2021 · External reference
Crystalline pancreatic ribonuclease. Introductory remarks
10.1111/j.1749-6632.1959.tb49332.x · 1959 · External reference
A common polymorphism in RNASE6 impacts its antimicrobial activity toward uropathogenic Escherichia coli
10.3390/ijms25010604 · 2024 · External reference
Cytostatic and cytotoxic properties of amphinase: a novel cytotoxic ribonuclease from Rana pipiens oocytes
10.4161/cc.6.24.5045 · 2007 · External reference
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases
10.1016/s0021-9258(18)52427-3 · 1991 · External reference
Stability and folding of amphibian ribonuclease a superfamily members in comparison with mammalian homologues
10.1111/febs.12891 · 2014 · External reference
Mouse eosinophil associated ribonucleases: mechanism of cytotoxic, antibacterial and antiparasitic activities
10.1016/j.ijbiomac.2016.10.041 · 2017 · External reference
Serum eosinophil-derived neurotoxin: a new promising biomarker for cow’s milk allergy diagnosis
10.1038/s41390-024-03260-x · 2024 · External reference
Biological function of pancreatic ribonuclease
10.1038/221340a0 · 1969 · External reference
The central role of translation elongation in response to stress
10.1042/bst20220584 · 2023 · External reference
The responses of the ribonuclease a superfamily to urinary tract infection
10.3389/fimmu.2019.02786 · 2019 · External reference
Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract
10.1038/ki.2014.268 · 2015 · External reference
Endothelial ribonuclease 1 in cardiovascular and systemic inflammation
10.3389/fcell.2020.576491 · 2020 · External reference
The molecular evolution of pancreatic ribonuclease.
10.1007/bf01796134 · 1977 · External reference
10.1016/b978-012588945-2/50009-1
10.1016/b978-012588945-2/50009-1 · External reference
10.1007/bf01796134
10.1007/bf01796134 · External reference
Evolutionary role of posttranslational modifications of proteins, as illustrated by the glycosylation characteristics of the digestive enzyme pancreatic ribonuclease
10.1007/bf02099959 · 1986 · External reference
The ribonuclease a superfamily: General discussion
10.1007/s000180050211 · 1998 · External reference
The metabolism of nucleic acids during embryonic development
10.1101/sqb.1947.012.01.005 · 1947 · External reference
Conformational studies of a series of overlapping peptides from ribonuclease and their relationship to the protein structure
10.1021/bi00835a027 · 1969 · External reference
Eukaryotic stress granules: the ins and outs of translation
10.1016/j.molcel.2009.11.020 · 2009 · External reference
Classical angiogenic signaling pathways and novel anti-angiogenic strategies for colorectal cancer
10.3390/cimb44100305 · 2022 · External reference
Human ribonuclease 9, a member of ribonuclease a superfamily, specifically expressed in epididymis, is a novel sperm-binding protein
10.1038/aja.2008.30 · 2009 · External reference
The ribonuclease a superfamily of mammals and birds: identifying new members and tracing evolutionary histories
10.1016/j.ygeno.2004.10.008 · 2005 · External reference
Zebrafish ribonucleases are bactericidal: implications for the origin of the vertebrate RNase a superfamily
10.1093/molbev/msm047 · 2007 · External reference
Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis
10.1007/s003350020007 · 2001 · External reference
T(H)2-mediated pulmonary inflammation leads to the differential expression of ribonuclease genes by alveolar macrophages
10.1165/rcmb.4882 · 2002 · External reference
Protective effects of recombinant human angiogenin in keratinocytes: new insights on oxidative stress response mediated by RNases
10.3390/ijms23158781 · 2022 · External reference
Tailoring the stress response of human skin cells by substantially limiting the nuclear localization of angiogenin
10.1016/j.heliyon.2024.e24556 · 2024 · External reference
Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease
10.1016/j.bbamem.2011.08.009 · 2011 · External reference
Cytostatic and cytotoxic effects of Pannon (P-30 protein), a novel anticancer agent
1988 · External reference
Recombinant human eosinophil-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus
10.1086/515322 · 1998 · External reference
Skin barrier-inflammatory pathway is a driver of the psoriasis-atopic dermatitis transition
2024 · External reference
The decomposition of yeast nucleic acid by a heat resistant enzyme
10.1126/science.85.2214.549 · 1937 · External reference
The decomposition of yeast nucleic acid by a heat-resistant enzyme
10.1016/s0021-9258(18)74055-6 · 1938 · External reference
Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly
10.1074/jbc.m109.077560 · 2010 · External reference
The catalytic activity and secretion of zebrafish RNases are essential for their in vivo function in motor neurons and vasculature
10.1038/s41598-018-37140-2 · 2019 · External reference
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells
10.1021/bi00341a030 · 1985 · External reference
A study of ribonuclease and desoxyribonuclease during the early developmental stages of Rana pipiens
10.1016/0014-4827(55)90129-4 · 1955 · External reference
The active site and mechanism of action of bovine pancreatic ribonuclease
10.1038/190781a0 · 1961 · External reference
10.1160/th10-06-0345
10.1160/th10-06-0345 · External reference
Tissue-specific expression of pancreatic-type RNases and RNase inhibitor in humans
10.1089/dna.1997.16.413 · 1997 · External reference
Identification and characterization of follistatin as a novel angiogenin-binding protein
10.1016/j.febslet.2007.10.059 · 2007 · External reference
Phenotype of ribonuclease 1 deficiency in mice
10.1261/rna.070433.119 · 2019 · External reference
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo
10.1016/j.jaci.2009.01.043 · 2009 · External reference
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty
10.1093/gbe/evt161 · 2013 · External reference
Onconase mediated NFKbeta downregulation in malignant pleural mesothelioma
10.1038/onc.2010.643 · 2011 · External reference
On the information expressed in enzyme structure: more lessons from ribonuclease A
10.1007/s11030-011-9307-4 · 2011 · External reference
Crystalline ribonuclease from bovine milk
10.3168/jds.s0022-0302(66)87829-3 · 1966 · External reference
Consequences of proline-to-alanine substitutions for the stability and refolding of onconase
10.1111/febs.12406 · 2013 · External reference
Ribonuclease inhibitor as an intracellular sentry
10.1093/nar/gkg163 · 2003 · External reference
Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs
10.1016/j.nbd.2019.104562 · 2019 · External reference
Pathways of folding of reduced bovine pancreatic ribonuclease
10.1021/bi00714a001 · 1974 · External reference
Characterization of poly-C-preferential ribonuclease from chicken liver
10.1093/oxfordjournals.jbchem.a124132 · 1993 · External reference
A human ribonuclease variant and ERK-pathway inhibitors exhibit highly synergistic toxicity for cancer cells
10.1158/1535-7163.mct-18-0724 · 2018 · External reference
Preparation of recombinant rat eosinophil-associated ribonuclease-1 and -2 and analysis of their biological activities
10.1016/s0925-4439(03)00077-2 · 2003 · External reference
Angiogenin-induced tRNA fragments inhibit translation initiation
10.1016/j.molcel.2011.06.022 · 2011 · External reference
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein
10.1016/j.jmb.2007.02.005 · 2007 · External reference
The action of boiled pancreas extract on yeast nucleic acid
10.1152/ajplegacy.1920.52.1.203 · 1920 · External reference
Synergy of interleukin (IL)-5 and IL-18 in eosinophil mediated pathogenesis of allergic diseases
10.1016/j.cytogfr.2019.05.003 · 2019 · External reference
Structure of the newly found green turtle egg-white ribonuclease
10.1107/s1744309110016751 · 2010 · External reference
Targeting angiogenin in therapy of amyotropic lateral sclerosis
10.1517/14728222.12.10.1229 · 2008 · External reference
Ribonuclease (RNase) prolongs survival of grafts in experimental heart transplantation
10.1161/jaha.116.003429 · 2016 · External reference
Isolation of a cDNA clone encoding the RNasesuperfamily-related gene highly expressed in chicken bone-marrow cells
10.1016/s0006-291x(05)80980-5 · 1992 · External reference
RNase 7 downregulates TH2 cytokine production by activated human T cells
10.1111/all.13173 · 2017 · External reference
RNase 7 promotes sensing of self-DNA by human keratinocytes and activates an antiviral immune response
10.1016/j.jid.2019.09.029 · 2020 · External reference
Selective activity of BS-RNase against anaplastic thyroid cancer
2001 · External reference
Epididymal protein Rnase10 is required for post-testicular sperm maturation and male fertility
10.1096/fj.12-205211 · 2012 · External reference
Crystalline ribonuclease
10.1085/jgp.24.1.15 · 1940 · External reference
Tight-binding inhibition of angiogenin and ribonuclease a by placental ribonuclease inhibitor
10.1021/bi00427a031 · 1989 · External reference
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
10.1038/s41467-021-23075-2 · 2021 · External reference
Functional roles of the human ribonuclease a superfamily in RNA metabolism and membrane receptor biology
10.1016/j.mam.2019.03.003 · 2019 · External reference
Cytotoxicity of bovine seminal ribonuclease: monomer versus dimer
10.1021/bi051668z · 2005 · External reference
Angiogenin reduces immune inflammation via inhibition of TANK-binding kinase 1 expression in human corneal fibroblast cells
10.1155/2014/861435 · 2014 · External reference
Ribonuclease a variants with potent cytotoxic activity
10.1073/pnas.95.18.10407 · 1998 · External reference
The purification and properties of chicken liver RNase: an enzyme which is useful in distinguishing between cytidylic and uridylic acid residues
10.1016/s0021-9258(19)86006-4 · 1980 · External reference
Ribonuclease 4 protects neuron degeneration by promoting angiogenesis, neurogenesis, and neuronal survival under stress
10.1007/s10456-012-9322-9 · 2013 · External reference
Cloning, expression and location of RNase9 in human epididymis
10.1186/1756-0500-1-111 · 2008 · External reference
Partial purification and some properties of a liver alkaline ribonuclease from the frog Rana esculenta
1979 · External reference
Research progress on the structure, function, and use of angiogenin in malignant tumours
10.1016/j.heliyon.2024.e30654 · 2024 · External reference
Alteration of human serum ribonuclease activity in malignancy
10.3109/10408367909149733 · 1978 · External reference
Phase II trial of a single weekly intravenous dose of ranpirnase in patients with unresectable malignant mesothelioma
10.1200/jco.2002.20.1.274 · 2002 · External reference
Angiogenin promotes tumoral growth and angiogenesis by regulating matrix metallopeptidase-2 expression via the ERK1/2 pathway
10.1038/onc.2014.2 · 2015 · External reference
Bovine pancreatic RNase A: an insight into the mechanism of antitumor activity in vitro and in vivo
10.3390/pharmaceutics14061173 · 2022 · External reference
Characterization of the angiogenic activity of zebrafish ribonucleases
10.1111/j.1742-4658.2009.07115.x · 2009 · External reference
Diminished expression of an antiviral ribonuclease in response to pneumovirus infection in vivo
10.1016/s0166-3542(03)00111-6 · 2003 · External reference
Brain-derived neurotrophic factor induces angiogenin secretion and nuclear translocation in human umbilical vein endothelial cells
10.1016/j.prp.2018.02.013 · 2018 · External reference
Refined 1.7A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity
10.1016/0022-2836(94)90017-5 · 1994 · External reference
Purification and properties of an alkaline ribonuclease from the hepatic cytosol fraction of bullfrog, Rana catesbeiana
10.1093/oxfordjournals.jbchem.a131251 · 1976 · External reference
Extracellular RNA induces neutrophil recruitment via toll-like receptor 3 during venous thrombosis after vascular injury
10.1161/jaha.124.034492 · 2024 · External reference
Identification of genes differentially expressed in two types of v-myb-transformed avian myelomonocytic cells
1992 · External reference
Single amino acid substitutions at the N-terminus of a recombinant cytotoxic ribonuclease markedly influence biochemical and biological properties
10.1021/bi972147h · 1998 · External reference
Oxidative stress in neurodegenerative diseases
10.1007/s12035-015-9337-5 · 2016 · External reference
Characterization of a ribonuclease gene and encoded protein from the reptile, Iguana iguana
10.1016/j.gene.2005.03.002 · 2005 · External reference
Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo
10.1038/sj.gene.6364143 · 2004 · External reference
Evolution and function of leukocyte RNase A ribonucleases of the avian species, Gallus gallus
10.1074/jbc.m604313200 · 2006 · External reference
Exploring the role of eosinophil cationic protein (ECP) in schizophrenia: insights and implications
10.1097/md.0000000000038380 · 2024 · External reference
Eosinophils contribute to innate antiviral immunity and promote clearance of respiratory syncytial virus
10.1182/blood-2007-01-071340 · 2007 · External reference
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish
10.1042/bj20100892 · 2011 · External reference
Ribonucleases with angiogenic and bactericidal activities from the Atlantic salmon
10.1111/j.1742-4658.2008.06289.x · 2008 · External reference
Ribonucleases and angiogenins from fish
10.1074/jbc.m605505200 · 2006 · External reference
The success of the RNase scaffold in the advance of biosciences and in evolution
10.1016/j.gene.2007.05.006 · 2007 · External reference
Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin to control growth and survival
2013 · External reference
A novel RNase 3/ECP peptide for pseudomonas aeruginosa biofilm eradication that combines antimicrobial, lipopolysaccharide binding, and cell-agglutinating activities
10.1128/aac.00830-16 · 2016 · External reference
New insights into the role of angiogenin in actin polymerization
10.1016/b978-0-12-394306-4.00011-3 · 2012 · External reference
Onconase downregulates microRNA expression through targeting microRNA precursors
10.1038/cr.2012.67 · 2012 · External reference
Antimicrobial peptides and proteins: interaction with the skin microbiota
10.1111/exd.14433 · 2021 · External reference
The antimicrobial and immunomodulatory function of RNase 7 in skin
10.3389/fimmu.2019.02553 · 2019 · External reference
et. RNase 7 in cutaneous defense
10.3390/ijms17040560 · 2016 · External reference
Ribonuclease A
10.1021/cr960427h · 1998 · External reference
Eosinophil-derived neurotoxin / RNase 2: connecting the past, the present and the future
10.2174/138920108784567236 · 2008 · External reference
Eosinophil-derived neurotoxin (EDN/RNase 2) and the mouse eosinophil-associated RNases (mEars): expanding roles in promoting host defense
10.3390/ijms160715442 · 2015 · External reference
Diversity among the primate eosinophil-derived neurotoxin genes: a specific C-terminal sequence is necessary for enhanced ribonuclease activity
10.1093/nar/25.17.3532 · 1997 · External reference
Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues
10.1093/nar/23.21.4290 · 1995 · External reference
Human ribonuclease 6 has a protective role during experimental urinary tract infection
10.1159/000534736 · 2023 · External reference
Angiogenin functionally interacts with p53 and regulates p53 mediated apoptosis and cell survival
10.1038/onc.2011.648 · 2012 · External reference
Angiogenin-cleaved tRNA halves interact with cytochrome c, protecting cells from apoptosis during osmotic stress
10.1128/mcb.00136-14 · 2014 · External reference
Exploring the mechanisms of action of human secretory RNase 3 and RNase 7 against Candida albicans
10.1002/mbo3.373 · 2016 · External reference
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase a family
10.1074/jbc.m108115200 · 2002 · External reference
Structural studies of pancreatic ribonuclease
1967 · External reference
Prenatal human skin expresses the antimicrobial peptide RNase 7
10.1007/s00403-013-1340-y · 2013 · External reference
The immunomodulatory and antimicrobial properties of the vertebrate ribonuclease a superfamily
10.3390/vaccines6040076 · 2018 · External reference
Epididymis-specific RNase a family genes regulate fertility and small RNA processing
10.1016/j.jbc.2024.107933 · 2024 · External reference
Three decades of research on angiogenin: a review and perspective
10.1093/abbs/gmv131 · 2015 · External reference
The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition
10.1016/j.ijbiomac.2021.04.041 · 2021 · External reference
IL-17A and IFN-γ synergistically induce RNase 7 expression via STAT3 in primary keratinocytes
10.1371/journal.pone.0059531 · 2013 · External reference
Bovine seminal RNase induces apoptosis in normal proliferating lymphocytes
10.1007/s005990070006 · 2000 · External reference
Enzymatic and structural characterisation of amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes
10.1016/j.jmb.2007.04.071 · 2007 · External reference
The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations
10.1016/s0021-9258(19)83984-4 · 1963 · External reference
Human pancreatic-type and nonpancreatic-type ribonucleases: a direct side-by-side comparison of their catalytic properties
10.1006/abbi.1994.1318 · 1994 · External reference
The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · 2010 · External reference
Immunosuppressive activity of bovine seminal ribonuclease and its mode of action
10.1016/s0171-2985(96)80045-3 · 1996 · External reference
An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract
10.1038/ki.2013.395 · 2014 · External reference
Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract
10.1038/ki.2012.410 · 2013 · External reference
A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis
10.1093/hmg/ddm095 · 2007 · External reference
The role of human ribonuclease a family in health and diseases: A systematic review
10.1016/j.isci.2022.105284 · 2022 · External reference
Ribonuclease 4 functions as an intestinal antimicrobial protein to maintain gut microbiota and metabolite homeostasis
10.1038/s41467-024-50223-1 · 2024 · External reference
The role of eosinophil-derived neurotoxin and vascular endothelial growth factor in the pathogenesis of eosinophilic asthma
10.3390/cells12091326 · 2023 · External reference
Interaction of onconase with the human ribonuclease inhibitor protein
10.1016/j.bbrc.2008.10.032 · 2008 · External reference
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
10.1002/ana.22611 · 2011 · External reference
A study of ribonuclease activity in venom of vietnam cobra
10.1186/s40781-017-0145-5 · 2017 · External reference
Eosinophil cationic protein (ECP)
10.1016/s1357-2725(97)00127-1 · 1998 · External reference
RNase 7 participates in cutaneous innate control of Corynebacterium amycolatum
10.1038/s41598-017-14383-z · 2017 · External reference
Translation dysregulation in neurodegenerative diseases: a focus on ALS
10.1186/s13024-023-00642-3 · 2023 · External reference
Angiogenin/ribonuclease 5 Is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer
10.1016/j.ccell.2018.02.012 · 2018 · External reference
Immunological assay of pancreatic ribonuclease in serum as an indicator of pancreatic cancer
1984 · External reference
Impaired sperm maturation in RNASE9 knockout mice
10.1095/biolreprod.113.116863 · 2014 · External reference
Structure of phosphate-free ribonuclease A refined at 1.26 A
10.1021/bi00408a010 · 1988 · External reference
Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis
10.1002/ana.21221 · 2007 · External reference
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
10.1016/s0021-9258(18)82252-9 · 1993 · External reference
Eosinophil-associated ribonuclease 11 Is a macrophage chemoattractant
10.1074/jbc.m114.626648 · 2015 · External reference
Angiogenin cleaves tRNA and promotes stress-induced translational repression
10.1083/jcb.200811106 · 2009 · External reference
Activation of angiogenin expression in macrophages by lipopolysaccharide via the TLR4/NF-κB pathway in colitis
2024 · External reference
The bactericidal action on Escherichia coli of ZF-RNase-3 is triggered by the suicidal action of the bacterium OmpT protease
10.1111/j.1742-4658.2010.07614.x · 2010 · External reference
Function of angiogenin and its role in neurological diseases
2024 · External reference
Evolution of the rodent eosinophil-associated RNase gene family by rapid gene sorting and positive selection
10.1073/pnas.080071397 · 2000 · External reference
Positive Darwinian selection after gene duplication in primate ribonuclease genes
10.1073/pnas.95.7.3708 · 1998 · External reference
RNase 8, a novel RNase A superfamily ribonuclease expressed uniquely in placenta
10.1093/nar/30.5.1169 · 2002 · External reference
Phospholipid scramblase 1 functionally interacts with angiogenin and regulates angiogenin-enhanced rRNA transcription
10.1159/000356604 · 2013 · External reference
Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis
10.1002/ana.21221 · ExternalCitation · doi-reference
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
10.1002/ana.22611 · ExternalCitation · doi-reference
Exploring the mechanisms of action of human secretory RNase 3 and RNase 7 against Candida albicans
10.1002/mbo3.373 · ExternalCitation · doi-reference
Human pancreatic-type and nonpancreatic-type ribonucleases: a direct side-by-side comparison of their catalytic properties
10.1006/abbi.1994.1318 · ExternalCitation · doi-reference
10.1007/bf01796134
10.1007/bf01796134 · ExternalCitation · doi-reference
Evolutionary role of posttranslational modifications of proteins, as illustrated by the glycosylation characteristics of the digestive enzyme pancreatic ribonuclease
10.1007/bf02099959 · ExternalCitation · doi-reference
The ribonuclease a superfamily: General discussion
10.1007/s000180050211 · ExternalCitation · doi-reference
Mouse eosinophil-associated ribonucleases: a unique subfamily expressed during hematopoiesis
10.1007/s003350020007 · ExternalCitation · doi-reference
Prenatal human skin expresses the antimicrobial peptide RNase 7
10.1007/s00403-013-1340-y · ExternalCitation · doi-reference
Bovine seminal RNase induces apoptosis in normal proliferating lymphocytes
10.1007/s005990070006 · ExternalCitation · doi-reference
Ribonuclease 4 protects neuron degeneration by promoting angiogenesis, neurogenesis, and neuronal survival under stress
10.1007/s10456-012-9322-9 · ExternalCitation · doi-reference
On the information expressed in enzyme structure: more lessons from ribonuclease A
10.1007/s11030-011-9307-4 · ExternalCitation · doi-reference
Oxidative stress in neurodegenerative diseases
10.1007/s12035-015-9337-5 · ExternalCitation · doi-reference
A study of ribonuclease and desoxyribonuclease during the early developmental stages of Rana pipiens
10.1016/0014-4827(55)90129-4 · ExternalCitation · doi-reference
Refined 1.7A X-ray crystallographic structure of P-30 protein, an amphibian ribonuclease with anti-tumor activity
10.1016/0022-2836(94)90017-5 · ExternalCitation · doi-reference
New insights into the role of angiogenin in actin polymerization
10.1016/b978-0-12-394306-4.00011-3 · ExternalCitation · doi-reference
10.1016/b978-012588945-2/50009-1
10.1016/b978-012588945-2/50009-1 · ExternalCitation · doi-reference
Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease
10.1016/j.bbamem.2011.08.009 · ExternalCitation · doi-reference
Interaction of onconase with the human ribonuclease inhibitor protein
10.1016/j.bbrc.2008.10.032 · ExternalCitation · doi-reference
Angiogenin/ribonuclease 5 Is an EGFR ligand and a serum biomarker for erlotinib sensitivity in pancreatic cancer
10.1016/j.ccell.2018.02.012 · ExternalCitation · doi-reference
Synergy of interleukin (IL)-5 and IL-18 in eosinophil mediated pathogenesis of allergic diseases
10.1016/j.cytogfr.2019.05.003 · ExternalCitation · doi-reference
Identification and characterization of follistatin as a novel angiogenin-binding protein
10.1016/j.febslet.2007.10.059 · ExternalCitation · doi-reference
The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · ExternalCitation · doi-reference
Characterization of a ribonuclease gene and encoded protein from the reptile, Iguana iguana
10.1016/j.gene.2005.03.002 · ExternalCitation · doi-reference
The success of the RNase scaffold in the advance of biosciences and in evolution
10.1016/j.gene.2007.05.006 · ExternalCitation · doi-reference
Tailoring the stress response of human skin cells by substantially limiting the nuclear localization of angiogenin
10.1016/j.heliyon.2024.e24556 · ExternalCitation · doi-reference
Research progress on the structure, function, and use of angiogenin in malignant tumours
10.1016/j.heliyon.2024.e30654 · ExternalCitation · doi-reference
Mouse eosinophil associated ribonucleases: mechanism of cytotoxic, antibacterial and antiparasitic activities
10.1016/j.ijbiomac.2016.10.041 · ExternalCitation · doi-reference
The structural features of an ancient ribonuclease from Salmo salar reveal an intriguing case of auto-inhibition
10.1016/j.ijbiomac.2021.04.041 · ExternalCitation · doi-reference
The role of human ribonuclease a family in health and diseases: A systematic review
10.1016/j.isci.2022.105284 · ExternalCitation · doi-reference
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo
10.1016/j.jaci.2009.01.043 · ExternalCitation · doi-reference
Epididymis-specific RNase a family genes regulate fertility and small RNA processing
10.1016/j.jbc.2024.107933 · ExternalCitation · doi-reference
RNase 7 promotes sensing of self-DNA by human keratinocytes and activates an antiviral immune response
10.1016/j.jid.2019.09.029 · ExternalCitation · doi-reference
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein
10.1016/j.jmb.2007.02.005 · ExternalCitation · doi-reference
Enzymatic and structural characterisation of amphinase, a novel cytotoxic ribonuclease from Rana pipiens oocytes
10.1016/j.jmb.2007.04.071 · ExternalCitation · doi-reference
Functional roles of the human ribonuclease a superfamily in RNA metabolism and membrane receptor biology
10.1016/j.mam.2019.03.003 · ExternalCitation · doi-reference
Eukaryotic stress granules: the ins and outs of translation
10.1016/j.molcel.2009.11.020 · ExternalCitation · doi-reference
Angiogenin-induced tRNA fragments inhibit translation initiation
10.1016/j.molcel.2011.06.022 · ExternalCitation · doi-reference
Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs
10.1016/j.nbd.2019.104562 · ExternalCitation · doi-reference
Brain-derived neurotrophic factor induces angiogenin secretion and nuclear translocation in human umbilical vein endothelial cells
10.1016/j.prp.2018.02.013 · ExternalCitation · doi-reference
The ribonuclease a superfamily of mammals and birds: identifying new members and tracing evolutionary histories
10.1016/j.ygeno.2004.10.008 · ExternalCitation · doi-reference
Isolation of a cDNA clone encoding the RNasesuperfamily-related gene highly expressed in chicken bone-marrow cells
10.1016/s0006-291x(05)80980-5 · ExternalCitation · doi-reference
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases
10.1016/s0021-9258(18)52427-3 · ExternalCitation · doi-reference
The decomposition of yeast nucleic acid by a heat-resistant enzyme
10.1016/s0021-9258(18)74055-6 · ExternalCitation · doi-reference
A cytotoxic ribonuclease. Study of the mechanism of onconase cytotoxicity
10.1016/s0021-9258(18)82252-9 · ExternalCitation · doi-reference
The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations
10.1016/s0021-9258(19)83984-4 · ExternalCitation · doi-reference
The purification and properties of chicken liver RNase: an enzyme which is useful in distinguishing between cytidylic and uridylic acid residues
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Eosinophil cationic protein (ECP)
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Ribonuclease A
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