Research graph
References from Overview: ribonucleases, a family of multifaceted proteins. Local targets link to admitted publications; unresolved targets remain external evidence.
Polymorphisms in the RNASE3 gene are associated with susceptibility to cerebral malaria in Ghanaian children
10.1371/journal.pone.0029465 · 2011 · External reference
In lysate RNA digestion provides insights into the angiogenin’s specificity towards transfer RNAs
10.1080/15476286.2021.1930758 · 2021 · External reference
Ribonucleases of mice and men: unveiling the roles of the rnase a superfamily in host defence
10.1155/jimr/3940139 · 2025 · External reference
A common polymorphism in RNASE6 impacts its antimicrobial activity toward uropathogenic Escherichia coli
10.3390/ijms25010604 · 2024 · External reference
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway
10.1016/j.molimm.2021.11.002 · 2022 · External reference
A natural classification of ribonucleases
10.1016/s0076-6879(01)41142-6 · 2001 · External reference
Ribonucleases as potential modalities in anticancer therapy
10.1016/j.ejphar.2009.06.067 · 2009 · External reference
Changes in the repertoire of tRNA-derived fragments in different blood cell populations
2024 · External reference
Myeloid cells protect intestinal epithelial barrier integrity through the angiogenin/plexin-B2 axis
10.15252/embj.2019103325 · 2020 · External reference
Eosinophil associated genes in the inflammatory bowel disease 4 region: correlation to inflammatory bowel disease revealed
10.3748/wjg.v18.i44.6409 · 2012 · External reference
Nucleotide binding architecture for secreted cytotoxic endoribonucleases
10.1016/j.biochi.2012.12.015 · 2013 · External reference
Role of the N terminus in RNase a homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity
10.1006/jmbi.1996.0218 · 1996 · External reference
The antipathogen activities of eosinophil cationic protein
10.2174/138920108784567353 · 2008 · External reference
Mammalian antimicrobial proteins and peptides: overview on the RNase A superfamily members involved in innate host defence
10.1039/b617527a · 2007 · External reference
Ancestral ribonucleases back in motion for evolutionary-dynamics guided protein design
10.1016/j.tibs.2024.06.005 · 2024 · External reference
Structural insights into human angiogenin variants implicated in Parkinson's disease and amyotrophic lateral sclerosis
10.1038/srep41996 · 2017 · External reference
RNase1 prevents the damaging interplay between extracellular RNA and tumour necrosis factor-α in cardiac ischaemia/reperfusion injury
10.1160/th14-08-0703 · 2014 · External reference
Angiogenin-mediated tsRNAs control inflammation and metabolic disorder by regulating NLRP3 inflammasome
10.1038/s41418-024-01311-8 · 2024 · External reference
Ribonucleases as drug targets
10.1016/j.tips.2018.07.005 · 2018 · External reference
Both aromatic and cationic residues contribute to the membrane-lytic and bactericidal activity of eosinophil cationic protein
10.1021/bi0273011 · 2003 · External reference
RNA Crossing Membranes: Systems and Mechanisms Contextualizing Extracellular RNA and Cell Surface GlycoRNAs.
10.1146/annurev-genom-101722-101224 · 2023 · External reference
Human ribonuclease 9, a member of ribonuclease A superfamily, specifically expressed in epididymis, is a novel sperm-binding protein
10.1038/aja.2008.30 · 2009 · External reference
The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories
10.1016/j.ygeno.2004.10.008 · 2005 · External reference
Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism
10.1021/bi201075b · 2011 · External reference
An old friend with a new face: tRNA-derived small RNAs with big regulatory potential in cancer biology
2023 · External reference
Genetic variants of RNASE3 (ECP) and susceptibility to severe malaria in Senegalese population
10.1186/s12936-018-2205-9 · 2018 · External reference
Recombinant human eosinophii-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus
10.1086/515322 · 1998 · External reference
The making and breaking of tRNAs by ribonucleases
10.1016/j.tig.2024.03.007 · 2024 · External reference
Comparison of the structural and functional properties of RNase a and BS-RNase: a stepwise mutagenesis approach
10.1002/bip.21176 · 2009 · External reference
The 434(G>C) polymorphism within the coding sequence of eosinophil cationic protein (ECP) correlates with the natural course of Schistosoma mansoni infection
10.1016/j.ijpara.2007.04.001 · 2007 · External reference
Influenza virus inactivated by artificial ribonucleases as a prospective killed virus vaccine
10.1016/j.vaccine.2012.02.051 · 2012 · External reference
Exploring the RNase a scaffold to combine catalytic and antimicrobial activities. Structural characterization of RNase 3/1 chimeras
10.3389/fmolb.2022.964717 · 2022 · External reference
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells
10.1016/j.bbamcr.2014.01.025 · 2014 · External reference
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
10.1016/j.bbamcr.2014.12.016 · 2015 · External reference
Small RNAs are modified with N-glycans and displayed on the surface of living cells
10.1016/j.cell.2021.04.023 · 2021 · External reference
Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition
10.1016/s0021-9258(17)31836-7 · 1994 · External reference
Viral genome cleavage with artificial ribonucleases: a new method to inactivate RNA-containing viruses
10.1134/s1607672909040140 · 2009 · External reference
Genetic signatures of positive selection in human populations adapted to high altitude in papua new Guinea
10.1093/gbe/evae161 · 2024 · External reference
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty
10.1093/gbe/evt161 · 2013 · External reference
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species.
10.1016/j.bbapap.2005.10.011 · 2006 · External reference
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.
10.1074/jbc.m207587200 · 2002 · External reference
Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia
10.1038/s41431-023-01327-7 · 2023 · External reference
Nucleases: from primitive immune defenders to modern biotechnology tools
10.1111/imm.13884 · 2025 · External reference
Evolutionary relationships among self-incompatibility RNases.
10.1073/pnas.231386798 · 2001 · External reference
Reconstructing the evolutionary history of the artiodactyl ribonuclease superfamily
10.1038/374057a0 · 1995 · External reference
Novel insight into mechanisms of ROS1 catalytic activation via loss of the extracellular domain
10.1038/s41598-024-71687-7 · 2024 · External reference
The RNA modification landscape in human disease
10.1261/rna.063503.117 · 2017 · External reference
The ribonuclease a superfamily in humans: canonical RNases as the buttress of innate immunity
10.3390/ijms17081278 · 2016 · External reference
Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation
2021 · External reference
Host defence RNases as antiviral agents against enveloped single stranded RNA viruses
10.1080/21505594.2021.1871823 · 2021 · External reference
Eosinophil degranulation: an evolutionary vestige or a universally destructive effector function?
10.1111/j.1365-2222.2005.02302.x · 2005 · External reference
A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy
10.1126/science.adp5384 · 2025 · External reference
Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs
2022 · External reference
Structural determinants for tRNA selective cleavage by RNase 2/EDN
10.1016/j.str.2023.12.012 · 2024 · External reference
Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma
10.1016/j.jhep.2020.09.030 · 2021 · External reference
Functional evolution of ribonuclease inhibitor: insights from birds and reptiles
10.1016/j.jmb.2014.06.007 · 2014 · External reference
Structural mechanism of angiogenin activation by the ribosome
10.1038/s41586-024-07508-8 · 2024 · External reference
Human antimicrobial RNases inhibit intracellular bacterial growth and induce autophagy in mycobacteria-infected macrophages
10.3389/fimmu.2019.01500 · 2019 · External reference
Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model
10.1007/s00018-020-03695-5 · 2021 · External reference
Immune modulation by human secreted RNases at the extracellular space
2018 · External reference
Selective cleavage of ncRNA and antiviral activity by RNase2/EDN in THP1-induced macrophages
10.1007/s00018-022-04229-x · 2022 · External reference
The human host defense ribonucleases 1, 3 and 7 are elevated in patients with sepsis after major surgery—a pilot study
10.3390/ijms17030294 · 2016 · External reference
The emerging role of GlycoRNAs in immune regulation and recognition
10.1016/j.imlet.2025.107048 · 2025 · External reference
The role of non-catalytic binding subsites in the endonuclease activity of bovine pancreatic ribonuclease A
10.1074/jbc.271.9.4687 · 1996 · External reference
The case of oxidative folding of ribonuclease A: factors impacting fold maturation of ER-processed proteins
2011 · External reference
Eosinophil-induced neurotoxicity: the role of eosinophil cationic protein/RNase 3
10.1016/j.jneuroim.2010.06.012 · 2010 · External reference
A study of ribonuclease activity in venom of vietnam cobra
10.1186/s40781-017-0145-5 · 2017 · External reference
The contribution of noncatalytic phosphate-binding subsites to the mechanism of bovine pancreatic ribonuclease A
10.1007/s000180050205 · 1998 · External reference
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus
10.1016/j.ijbiomac.2023.126110 · 2023 · External reference
Bacterial RNA sensing by TLR8 requires RNase 6 processing and is inhibited by RNA 2’O-methylation
10.1038/s44319-024-00281-9 · 2024 · External reference
Exploring the role of eosinophil cationic protein (ECP) in schizophrenia: insights and implications
2024 · External reference
RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication
10.1016/j.medj.2023.04.001 · 2023 · External reference
Origin of the catalytic activity of bovine seminal ribonuclease against double-stranded RNA
10.1021/bi9722047 · 1998 · External reference
Immune sensing of synthetic, bacterial, and protozoan RNA by toll-like receptor 8 requires coordinated processing by RNase T2 and RNase 2
10.1016/j.immuni.2020.03.009 · 2020 · External reference
Structure and function of ribonuclease A binding subsites
1991 · External reference
Bertrand, Infection-induced 5′-half molecules of tRNAHisGUG activate Toll-like receptor 7
10.1371/journal.pbio.3000982 · 2020 · External reference
The tRNA Val half: A strong endogenous Toll-like receptor 7 ligand with a 5′-terminal universal sequence signature
10.1073/pnas.2319569121 · 2024 · External reference
Ribonuclease 7 polymorphism rs1263872 reduces antimicrobial activity and associates with pediatric urinary tract infections
10.1172/jci149807 · 2021 · External reference
Ribonucleases with angiogenic and bactericidal activities from the Atlantic salmon
10.1111/j.1742-4658.2008.06289.x · 2008 · External reference
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish
10.1042/bj20100892 · 2010 · External reference
The success of the RNase scaffold in the advance of biosciences and in evolution
10.1016/j.gene.2007.05.006 · 2007 · External reference
Structure-based design of an rnase chimera for antimicrobial therapy
10.3390/ijms23010095 · 2022 · External reference
Testing a human antimicrobial RNase chimera against bacterial resistance
10.3389/fmicb.2019.01357 · 2019 · External reference
Insights into the antimicrobial mechanism of action of human RNase6: structural determinants for bacterial cell agglutination and membrane permeation
10.3390/ijms17040552 · 2016 · External reference
Towards the rational design of antimicrobial proteins: single point mutations can switch on bactericidal and agglutinating activities on the RNase A superfamily lineage
10.1111/febs.12506 · 2013 · External reference
Two human host defense ribonucleases against mycobacteria, the eosinophil cationic protein (RNase 3) and RNase 7
10.1128/aac.00428-13 · 2013 · External reference
Ribonuclease A
10.1021/cr960427h · 1998 · External reference
Eosinophil-derived neurotoxin / RNase 2: connecting the past, the present and the future
10.2174/138920108784567236 · 2008 · External reference
10.1006/excr.1999.4718
10.1006/excr.1999.4718 · External reference
Fecal eosinophil granule-derived proteins reflect disease activity in inflammatory bowel disease
10.1111/j.1572-0241.1999.01640.x · 1999 · External reference
Mapping the eosinophil cationic protein antimicrobial activity by chemical and enzymatic cleavage
10.1016/j.biochi.2010.10.005 · 2011 · External reference
Rationally modified antimicrobial peptides from the N-Terminal domain of human RNase 3 show exceptional serum stability
10.1021/acs.jmedchem.1c00795 · 2021 · External reference
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family
10.1074/jbc.m108115200 · 2002 · External reference
Epididymis-specific RNase A family genes regulate fertility and small RNA processing
10.1016/j.jbc.2024.107933 · 2024 · External reference
Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals
10.1126/science.aad6780 · 2016 · External reference
Nucleoside tetra- and pentaphosphates prepared using a tetraphosphorylation reagent are potent inhibitors of ribonuclease A
10.1021/jacs.9b09760 · 2019 · External reference
The dual role of ribonucleases in tumor-host relationship
10.32471/exp-oncology.2312-8852.vol-41-no-3.13456 · 2019 · External reference
Assay for ribosome stimulation of angiogenin nuclease activity
2025 · External reference
The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · 2010 · External reference
Ribonuclease inhibitor and angiogenin system regulates cell type–specific global translation
10.1126/sciadv.adl0320 · 2024 · External reference
Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing
10.1074/jbc.ra119.009272 · 2019 · External reference
Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction
10.1038/7010 · 1999 · External reference
Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity
10.1016/j.bmc.2016.02.007 · 2016 · External reference
Eosinophil cationic protein aggregation: identification of an N-terminus amyloid prone region
10.1021/bm100334u · 2010 · External reference
Eosinophil cationic protein high-affinity binding to bacteria-wall lipopolysaccharides and peptidoglycans
10.1021/bi702065b · 2008 · External reference
Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment.
10.1042/bj20082330 · 2009 · External reference
Exploring new biological functions of amyloids: bacteria cell agglutination mediated by host protein aggregation
10.1371/journal.ppat.1003005 · 2012 · External reference
AMPA: an automated web server for prediction of protein antimicrobial regions
2012 · External reference
Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus
10.1042/bj20130123 · 2013 · External reference
Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases
10.1016/j.jbc.2024.107280 · 2024 · External reference
The functional heterogeneity of eosinophil cationic protein is determined by a gene polymorphism and post-translational modifications
10.1111/j.1365-2222.2007.02644.x · 2007 · External reference
Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease
10.1046/j.1365-2222.1999.00542.x · 1999 · External reference
A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases
10.1186/s12929-018-0484-7 · 2018 · External reference
Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection
10.1186/s12981-021-00399-z · 2021 · External reference
Sensitive detection of SARS-CoV-2 main protease 3CLpro with an engineered ribonuclease zymogen
10.1002/pro.4916 · 2024 · External reference
Ribonuclease 1 induces T-cell dysfunction and impairs CD8+ T-cell cytotoxicity to benefit tumor growth through hijacking STAT1
10.1002/advs.202404961 · 2025 · External reference
Activation of angiogenin expression in macrophages by lipopolysaccharide via the TLR4/NF-κB pathway in colitis
2024 · External reference
Elucidating common pathogenic transcriptional networks in infective endocarditis and sepsis: integrated insights from biomarker discovery and single-cell RNA sequencing
2023 · External reference
Plexin-B2 mediates physiologic and pathologic functions of angiogenin
10.1016/j.cell.2017.10.005 · 2017 · External reference
Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis
10.1172/jci.insight.131571 · 2020 · External reference
The structures of rnase a complexed with 3′-CMP and d(CpA): active site conformation and conserved water molecules
10.1002/pro.5560031217 · 1994 · External reference
Extracellular ribonucleic acids (RNA) enter the stage in cardiovascular disease
10.1161/circresaha.115.307961 · 2016 · External reference
Cell surface RNAs control neutrophil function
2023 · External reference
A Neglected Gene: The Role of the ANG Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis.
10.14336/ad.2024.0107 · 2024 · External reference
Ribonuclease 1 induces T-cell dysfunction and impairs CD8+ T-cell cytotoxicity to benefit tumor growth through hijacking STAT1
10.1002/advs.202404961 · ExternalCitation · doi-reference
Comparison of the structural and functional properties of RNase a and BS-RNase: a stepwise mutagenesis approach
10.1002/bip.21176 · ExternalCitation · doi-reference
Sensitive detection of SARS-CoV-2 main protease 3CLpro with an engineered ribonuclease zymogen
10.1002/pro.4916 · ExternalCitation · doi-reference
The structures of rnase a complexed with 3′-CMP and d(CpA): active site conformation and conserved water molecules
10.1002/pro.5560031217 · ExternalCitation · doi-reference
10.1006/excr.1999.4718
10.1006/excr.1999.4718 · ExternalCitation · doi-reference
Role of the N terminus in RNase a homologues: differences in catalytic activity, ribonuclease inhibitor interaction and cytotoxicity
10.1006/jmbi.1996.0218 · ExternalCitation · doi-reference
Human RNase3 immune modulation by catalytic-dependent and independent modes in a macrophage-cell line infection model
10.1007/s00018-020-03695-5 · ExternalCitation · doi-reference
Selective cleavage of ncRNA and antiviral activity by RNase2/EDN in THP1-induced macrophages
10.1007/s00018-022-04229-x · ExternalCitation · doi-reference
The contribution of noncatalytic phosphate-binding subsites to the mechanism of bovine pancreatic ribonuclease A
10.1007/s000180050205 · ExternalCitation · doi-reference
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells
10.1016/j.bbamcr.2014.01.025 · ExternalCitation · doi-reference
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
10.1016/j.bbamcr.2014.12.016 · ExternalCitation · doi-reference
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species.
10.1016/j.bbapap.2005.10.011 · ExternalCitation · doi-reference
Mapping the eosinophil cationic protein antimicrobial activity by chemical and enzymatic cleavage
10.1016/j.biochi.2010.10.005 · ExternalCitation · doi-reference
Nucleotide binding architecture for secreted cytotoxic endoribonucleases
10.1016/j.biochi.2012.12.015 · ExternalCitation · doi-reference
Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity
10.1016/j.bmc.2016.02.007 · ExternalCitation · doi-reference
Plexin-B2 mediates physiologic and pathologic functions of angiogenin
10.1016/j.cell.2017.10.005 · ExternalCitation · doi-reference
Small RNAs are modified with N-glycans and displayed on the surface of living cells
10.1016/j.cell.2021.04.023 · ExternalCitation · doi-reference
Ribonucleases as potential modalities in anticancer therapy
10.1016/j.ejphar.2009.06.067 · ExternalCitation · doi-reference
The eight human “canonical” ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · ExternalCitation · doi-reference
The success of the RNase scaffold in the advance of biosciences and in evolution
10.1016/j.gene.2007.05.006 · ExternalCitation · doi-reference
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus
10.1016/j.ijbiomac.2023.126110 · ExternalCitation · doi-reference
The 434(G>C) polymorphism within the coding sequence of eosinophil cationic protein (ECP) correlates with the natural course of Schistosoma mansoni infection
10.1016/j.ijpara.2007.04.001 · ExternalCitation · doi-reference
The emerging role of GlycoRNAs in immune regulation and recognition
10.1016/j.imlet.2025.107048 · ExternalCitation · doi-reference
Immune sensing of synthetic, bacterial, and protozoan RNA by toll-like receptor 8 requires coordinated processing by RNase T2 and RNase 2
10.1016/j.immuni.2020.03.009 · ExternalCitation · doi-reference
Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases
10.1016/j.jbc.2024.107280 · ExternalCitation · doi-reference
Epididymis-specific RNase A family genes regulate fertility and small RNA processing
10.1016/j.jbc.2024.107933 · ExternalCitation · doi-reference
Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma
10.1016/j.jhep.2020.09.030 · ExternalCitation · doi-reference
Functional evolution of ribonuclease inhibitor: insights from birds and reptiles
10.1016/j.jmb.2014.06.007 · ExternalCitation · doi-reference
Eosinophil-induced neurotoxicity: the role of eosinophil cationic protein/RNase 3
10.1016/j.jneuroim.2010.06.012 · ExternalCitation · doi-reference
RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication
10.1016/j.medj.2023.04.001 · ExternalCitation · doi-reference
Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway
10.1016/j.molimm.2021.11.002 · ExternalCitation · doi-reference
Structural determinants for tRNA selective cleavage by RNase 2/EDN
10.1016/j.str.2023.12.012 · ExternalCitation · doi-reference
Ancestral ribonucleases back in motion for evolutionary-dynamics guided protein design
10.1016/j.tibs.2024.06.005 · ExternalCitation · doi-reference
The making and breaking of tRNAs by ribonucleases
10.1016/j.tig.2024.03.007 · ExternalCitation · doi-reference
Ribonucleases as drug targets
10.1016/j.tips.2018.07.005 · ExternalCitation · doi-reference
Influenza virus inactivated by artificial ribonucleases as a prospective killed virus vaccine
10.1016/j.vaccine.2012.02.051 · ExternalCitation · doi-reference
The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories
10.1016/j.ygeno.2004.10.008 · ExternalCitation · doi-reference
Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition
10.1016/s0021-9258(17)31836-7 · ExternalCitation · doi-reference
A natural classification of ribonucleases
10.1016/s0076-6879(01)41142-6 · ExternalCitation · doi-reference
Rationally modified antimicrobial peptides from the N-Terminal domain of human RNase 3 show exceptional serum stability
10.1021/acs.jmedchem.1c00795 · ExternalCitation · doi-reference
Both aromatic and cationic residues contribute to the membrane-lytic and bactericidal activity of eosinophil cationic protein
10.1021/bi0273011 · ExternalCitation · doi-reference
Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism
10.1021/bi201075b · ExternalCitation · doi-reference
Eosinophil cationic protein high-affinity binding to bacteria-wall lipopolysaccharides and peptidoglycans
10.1021/bi702065b · ExternalCitation · doi-reference
Origin of the catalytic activity of bovine seminal ribonuclease against double-stranded RNA
10.1021/bi9722047 · ExternalCitation · doi-reference
Eosinophil cationic protein aggregation: identification of an N-terminus amyloid prone region
10.1021/bm100334u · ExternalCitation · doi-reference
Ribonuclease A
10.1021/cr960427h · ExternalCitation · doi-reference
Nucleoside tetra- and pentaphosphates prepared using a tetraphosphorylation reagent are potent inhibitors of ribonuclease A
10.1021/jacs.9b09760 · ExternalCitation · doi-reference
Reconstructing the evolutionary history of the artiodactyl ribonuclease superfamily
10.1038/374057a0 · ExternalCitation · doi-reference
Engineering receptor-mediated cytotoxicity into human ribonucleases by steric blockade of inhibitor interaction
10.1038/7010 · ExternalCitation · doi-reference
Human ribonuclease 9, a member of ribonuclease A superfamily, specifically expressed in epididymis, is a novel sperm-binding protein
10.1038/aja.2008.30 · ExternalCitation · doi-reference
Angiogenin-mediated tsRNAs control inflammation and metabolic disorder by regulating NLRP3 inflammasome
10.1038/s41418-024-01311-8 · ExternalCitation · doi-reference
Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia
10.1038/s41431-023-01327-7 · ExternalCitation · doi-reference
Structural mechanism of angiogenin activation by the ribosome
10.1038/s41586-024-07508-8 · ExternalCitation · doi-reference
Novel insight into mechanisms of ROS1 catalytic activation via loss of the extracellular domain
10.1038/s41598-024-71687-7 · ExternalCitation · doi-reference
Bacterial RNA sensing by TLR8 requires RNase 6 processing and is inhibited by RNA 2’O-methylation
10.1038/s44319-024-00281-9 · ExternalCitation · doi-reference
Structural insights into human angiogenin variants implicated in Parkinson's disease and amyotrophic lateral sclerosis
10.1038/srep41996 · ExternalCitation · doi-reference
Mammalian antimicrobial proteins and peptides: overview on the RNase A superfamily members involved in innate host defence
10.1039/b617527a · ExternalCitation · doi-reference
Bactericidal and membrane disruption activities of the eosinophil cationic protein are largely retained in an N-terminal fragment.
10.1042/bj20082330 · ExternalCitation · doi-reference
A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish
10.1042/bj20100892 · ExternalCitation · doi-reference
Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus
10.1042/bj20130123 · ExternalCitation · doi-reference
Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease
10.1046/j.1365-2222.1999.00542.x · ExternalCitation · doi-reference
Evolutionary relationships among self-incompatibility RNases.
10.1073/pnas.231386798 · ExternalCitation · doi-reference
The tRNA Val half: A strong endogenous Toll-like receptor 7 ligand with a 5′-terminal universal sequence signature
10.1073/pnas.2319569121 · ExternalCitation · doi-reference
The role of non-catalytic binding subsites in the endonuclease activity of bovine pancreatic ribonuclease A
10.1074/jbc.271.9.4687 · ExternalCitation · doi-reference
Entry into cells and selective degradation of tRNAs by a cytotoxic member of the RNase A family
10.1074/jbc.m108115200 · ExternalCitation · doi-reference
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.
10.1074/jbc.m207587200 · ExternalCitation · doi-reference
Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing
10.1074/jbc.ra119.009272 · ExternalCitation · doi-reference
In lysate RNA digestion provides insights into the angiogenin’s specificity towards transfer RNAs
10.1080/15476286.2021.1930758 · ExternalCitation · doi-reference
Host defence RNases as antiviral agents against enveloped single stranded RNA viruses
10.1080/21505594.2021.1871823 · ExternalCitation · doi-reference
Recombinant human eosinophii-derived neurotoxin/RNase 2 functions as an effective antiviral agent against respiratory syncytial virus
10.1086/515322 · ExternalCitation · doi-reference
Genetic signatures of positive selection in human populations adapted to high altitude in papua new Guinea
10.1093/gbe/evae161 · ExternalCitation · doi-reference
The expansion and functional diversification of the mammalian ribonuclease a superfamily epitomizes the efficiency of multigene families at generating biological novelty
10.1093/gbe/evt161 · ExternalCitation · doi-reference
Towards the rational design of antimicrobial proteins: single point mutations can switch on bactericidal and agglutinating activities on the RNase A superfamily lineage
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