Research graph
References from From monomers to multimers. Local targets link to admitted publications; unresolved targets remain external evidence.
Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease
10.1073/pnas.91.8.2915 · 1994 · External reference
BS-RNase tetramers: an example of domain-swapped oligomers
10.1016/s0014-5793(96)01034-4 · 1996 · External reference
Principles that govern the folding of protein chains
10.1126/science.181.4096.223 · 1973 · External reference
Amino acid sequence of an anti-tumor protein from Rana pipiens oocytes and early embryos. Homology to pancreatic ribonucleases
10.1016/s0021-9258(18)52427-3 · 1991 · External reference
Human pancreatic ribonuclease
10.1111/j.1432-1033.1997.t01-1-00465.x · 1997 · External reference
Biological function of pancreatic ribonuclease
10.1038/221340a0 · 1969 · External reference
Inhibition of tumor cell proliferation by dimerized ribonuclease
10.1073/pnas.73.2.573 · 1976 · External reference
Pancreatic ribonuclease: enzymic and physiological properties of a cross-linked dimer
10.1126/science.186.4162.444 · 1974 · External reference
The amino acid sequence of human pancreatic ribonuclease
10.1016/0003-2697(84)90306-3 · 1984 · External reference
Domain swapping: entangling alliances between proteins
10.1073/pnas.91.8.3127 · 1994 · External reference
Deposition diseases and 3D domain swapping
10.1016/j.str.2006.03.011 · 2006 · External reference
3D domain swapping: a mechanism for oligomer assembly
10.1002/pro.5560041202 · 1995 · External reference
Crystal structure of eosinophil cationic protein at 2.4A resolution
10.1021/bi9919145 · 1999 · External reference
Reverse transphosphorylation by ribonuclease a needs an intact p2-binding site. Point mutations at Lys-7 and Arg-10 alter the catalytic properties of the enzyme
10.1016/s0021-9258(17)41977-6 · 1994 · External reference
The antipathogen activities of eosinophil cationic protein
10.2174/138920108784567353 · 2008 · External reference
New muteins of RNase A with enhanced antitumor action
10.1016/s0014-5793(98)01221-6 · 1998 · External reference
The antitumor action of seminal ribonuclease and its quaternary conformations
10.1016/0014-5793(94)01450-f · 1995 · External reference
The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization
10.1016/s0969-2126(01)00659-1 · 2001 · External reference
Both aromatic and cationic residues contribute to the membrane-lytic and bactericidal activity of eosinophil cationic protein
10.1021/bi0273011 · 2003 · External reference
Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation
10.1007/s11010-005-4777-2 · 2005 · External reference
Cellular uptake of ribonuclease a relies on anionic glycans
10.1021/bi1013485 · 2010 · External reference
Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnase
10.1080/07357900500283143 · 2005 · External reference
Elucidation of the ribonuclease a aggregation process mediated by 3D domain swapping: a computational approach reveals possible new multimeric structures
10.1002/bip.20833 · 2008 · External reference
On the aggregation of bovine pancreatic ribonuclease
1962 · External reference
On the preparation of bovine pancreatic ribonuclease A
10.1016/s0021-9258(18)81307-2 · 1963 · External reference
Bull semen ribonucleases: 1. Purification and physico-chemical properties of the major component
10.1111/j.1432-1033.1972.tb01751.x · 1972 · External reference
Dimeric structure of seminal ribonuclease
10.1016/0014-5793(72)80642-2 · 1972 · External reference
Upregulation of miR-34a-5p, miR-20a-3p and miR-29a-3p by Onconase in A375 melanoma cells correlates with the downregulation of specific onco-proteins
10.3390/ijms23031647 · 2022 · External reference
Structural determinants of enzymic processivity
10.1021/bi00186a001 · 1994 · External reference
A residue to residue hydrogen bond mediates the nucleotide specificity of ribonuclease A
10.1006/jmbi.1995.0500 · 1995 · External reference
Ribonuclease A can be transformed into a dimeric ribonuclease with antitumor activity
10.1016/s0021-9258(17)32451-1 · 1994 · External reference
A new mutant of bovine seminal ribonuclease with a reversed swapping propensity
10.1021/bi0613630 · 2007 · External reference
Comparison of the structural and functional properties of RNase A and BS-RNase: a stepwise mutagenesis approach
10.1002/bip.21176 · 2009 · External reference
Acidity generated by the tumor microenvironment drives local invasion
10.1158/0008-5472.can-12-2796 · 2013 · External reference
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping
10.1016/j.bbapap.2016.10.008 · 2017 · External reference
Onconase dimerization through 3D domain swapping: structural investigations and increase in the apoptotic effect in cancer cells*
10.1042/bcj20170541 · 2017 · External reference
Dimerization of human angiogenin and of variants involved in neurodegenerative diseases
10.3390/ijms221810068 · 2021 · External reference
The Destabilizing Effect Of Ribonuclease On The Helical Dna Structure
10.1073/pnas.50.4.644 · 1963 · External reference
Interaction of platinum-based drugs with proteins: an overview of representative crystallographic studies
10.2174/18734294mta3bnjea5 · 2021 · External reference
Cytotoxicity and binding to DNA, lysozyme, ribonuclease a, and human serum albumin of the diiodido analog of picoplatin
10.1021/acs.inorgchem.4c05424 · 2025 · External reference
Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells
10.1021/bi00341a030 · 1985 · External reference
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells
10.1016/j.bbamcr.2014.01.025 · 2014 · External reference
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
10.1016/j.bbamcr.2014.12.016 · 2015 · External reference
Preparation and properties of two active forms of ribonuclease dimer
10.1016/s0021-9258(18)97123-1 · 1965 · External reference
Intracellular delivery of proteins into mammalian living cells by polyethylenimine-cationization
10.1263/jbb.99.95 · 2005 · External reference
Emerging biological functions of ribonuclease 1 and angiogenin
10.1080/10409238.2021.2004577 · 2022 · External reference
Biochemical and functional similarities between human eosinophil-derived neurotoxin and eosinophil cationic protein: homology with ribonuclease
10.1073/pnas.83.10.3146 · 1986 · External reference
Identifying the amylome, proteins capable of forming amyloid-like fibrils
10.1073/pnas.0915166107 · 2010 · External reference
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action
10.1016/s0014-5793(97)01147-2 · 1997 · External reference
Two different forms of aggregated dimers of ribonuclease A
10.1016/s0167-4838(98)00087-9 · 1998 · External reference
Structural versatility of bovine ribonuclease A. Distinct conformers of trimeric and tetrameric aggregates of the enzyme
10.1046/j.1432-1327.1999.00761.x · 1999 · External reference
Thermal aggregation of ribonuclease A. A contribution to the understanding of the role of 3D domain swapping in protein aggregation
10.1074/jbc.m213146200 · 2003 · External reference
Glycosylation and specific deamidation of ribonuclease B affect the formation of three-dimensional domain-swapped oligomers
10.1074/jbc.m308470200 · 2003 · External reference
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species
10.1016/j.bbapap.2005.10.011 · 2006 · External reference
Increase of RNase A N-terminus polarity or C-terminus apolarity changes the two domains' propensity to swap and form the two dimeric conformers of the protein
10.1021/bi060933t · 2006 · External reference
Double domain swapping in bovine seminal RNase: formation of distinct N- and C-swapped tetramers and multimers with increasing biological activities
10.1371/journal.pone.0046804 · 2012 · External reference
Biological activities of secretory RNases: focus on their oligomerization to design antitumor drugs
10.3389/fimmu.2019.02626 · 2019 · External reference
The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme
10.1016/j.ijbiomac.2021.09.095 · 2021 · External reference
Slow evolution toward “super-aggregation” of the oligomers formed through the swapping of RNase A N-termini: a wish for amyloidosis?
10.3390/ijms231911192 · 2022 · External reference
Effects of pathogenic mutants of the neuroprotective RNase 5-angiogenin in amyotrophic lateral sclerosis (ALS)
10.3390/genes15060738 · 2024 · External reference
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
10.1038/ng1742 · 2006 · External reference
Mild hyperthermia predisposes tumor cells to undergo apoptosis upon treatment with onconase
2007 · External reference
Cross-linking of bovine pancreatic ribonuclease a with dimethyl adipimidate
10.1021/bi00860a021 · 1967 · External reference
Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress
10.1074/jbc.ra119.008491 · 2019 · External reference
G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments
10.1073/pnas.1407361111 · 2014 · External reference
Cross-linking of α-chymotrypsin and other proteins by reaction with glutaraldehyde
10.1016/0003-9861(71)90492-9 · 1971 · External reference
Effects of glycosylation on protein structure and dynamics in ribonuclease B and some of its individual glycoforms
10.1111/j.1432-1033.1993.tb18370.x · 1993 · External reference
Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein
10.1016/j.jmb.2007.02.005 · 2007 · External reference
Tertiary structure of ribonuclease
10.1038/213862a0 · 1967 · External reference
Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures
10.1021/bi00164a004 · 1992 · External reference
Mechanism of ribonuclease cytotoxicity
10.1074/jbc.270.52.31097 · 1995 · External reference
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
10.1038/366751a0 · 1993 · External reference
Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A
10.1006/jmbi.1996.0694 · 1996 · External reference
Action of ribonuclease on certain ascites tumours
10.1038/175258b0 · 1955 · External reference
Endocytotic internalization as a crucial factor for the cytotoxicity of ribonucleases
10.1074/jbc.m702240200 · 2007 · External reference
A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease
10.1016/s0014-5793(00)01804-4 · 2000 · External reference
The ribonucleolytic activity of angiogenin
10.1021/bi0117899 · 2002 · External reference
Structural study of the carbohydrate moiety of bovine pancreatic ribonuclease B1
1980 · External reference
Breakdown of double-stranded RNA by bull semen ribonuclease
10.1111/j.1432-1033.1969.tb00498.x · 1969 · External reference
Oligomerization of bovine ribonuclease A: structural and functional features of its multimers
10.1042/bj20031922 · 2004 · External reference
Revisiting the action of bovine ribonuclease A and pancreatic-type ribonucleases on double-stranded RNA
10.1007/bf00230753 · 1992 · External reference
The crystal structure of a 3D domain-swapped dimer of RNase A at a 2.1-Å resolution
10.1073/pnas.95.7.3437 · 1998 · External reference
A domain-swapped RNase A dimer with implications for amyloid formation
10.1038/84941 · 2001 · External reference
Structures of the two 3D domain-swapped RNase A trimers
10.1110/ps.36602 · 2002 · External reference
3D domain swapping: as domains continue to swap
10.1110/ps.0201402 · 2002 · External reference
Formation, structure, and dissociation of the ribonuclease S three-dimensional domain-swapped dimer
10.1074/jbc.m510491200 · 2006 · External reference
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation
10.1016/j.abb.2009.07.013 · 2009 · External reference
Carbodiimide EDC induces cross-links that stabilize RNase a C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity
10.1021/bc9001486 · 2009 · External reference
Unravelling the amyloid aggregation mechanism of the sweet protein Monellin: insights from circular permutated mutants
10.1016/j.ijbiomac.2025.142239 · 2025 · External reference
Key extracellular and intracellular steps in the antitumor action of seminal ribonuclease
10.1111/j.1432-1033.1995.tb20557.x · 1995 · External reference
Specific effect of bull seminal ribonuclease (AS RNase) on cell systems in mice
10.1016/0300-9629(73)90415-5 · 1973 · External reference
Antitumor activity and other biological actions of oligomers of ribonuclease A
10.1074/jbc.m302711200 · 2003 · External reference
Bovine seminal ribonuclease: structure at 1.9Å resolution
10.1107/s0907444993003403 · 1993 · External reference
Role of the ribonuclease ONCONASE in miRNA biogenesis and tRNA processing: focus on cancer and viral infections
10.3390/ijms23126556 · 2022 · External reference
The buried diversity of bovine seminal ribonuclease: shape and cytotoxicity of the swapped non-covalent form of the enzyme
10.1016/j.jmb.2007.11.008 · 2008 · External reference
Solid phase synthesis
10.1126/science.3961484 · 1986 · External reference
Protein metalation by metal-based drugs: X-ray crystallography and mass spectrometry studies
10.1039/c7cc06442j · 2017 · External reference
Invitro synergism between a novel amphibian oocytic ribonuclease (onconase(r)) and tamoxifen, lovastatin and Cisplatin, in human ovcar-3 ovarian-carcinoma cell-line
10.3892/ijo.1.7.779 · 1992 · External reference
Phase I human clinical trial of ONCONASE® (P-30 protein) administered intravenously on a weekly schedule in cancer patients with solid tumors
1993 · External reference
Relationship between response rate and median survival in patients with advanced non-small cell lung cancer: comparison of ONCONASE(®) with other anticancer agents
1995 · External reference
Purification and characterization of three ribonucleases from human kidney: comparison with urine ribonucleases
10.1016/0003-9861(90)90424-w · 1990 · External reference
Rnase a domain-swapped dimers produced through different methods: structure–catalytic properties and antitumor activity
2021 · External reference
Identification of the nucleolar targeting signal of human angiogenin
10.1006/bbrc.1994.2391 · 1994 · External reference
Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor
10.1016/j.febslet.2005.03.087 · 2005 · External reference
Different susceptibility of the two dimers of ribonuclease A to subtilisin. Implications for their structure
10.1016/s0167-4838(00)00287-9 · 2001 · External reference
Structural properties of trimers and tetramers of ribonuclease A
10.1110/ps.14101 · 2001 · External reference
Ribonuclease inhibitor 1 emerges as a potential biomarker and modulates inflammation and iron homeostasis in sepsis
10.1038/s41598-024-65778-8 · 2024 · External reference
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
10.1126/science.1134108 · 2006 · External reference
Bovine pancreatic ribonuclease A as a model of an enzyme with multiple substrate binding sites
10.1016/0167-4838(95)00138-k · 1995 · External reference
Breakdown of supersaturation barrier links protein folding to amyloid formation
10.1038/s42003-020-01641-6 · 2021 · External reference
Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus
10.1016/j.ijbiomac.2023.126110 · 2023 · External reference
Onconase induces apoptosis in dabrafenib-resistant melanoma cell lines through dysregulation of ROS homeostasis, antioxidant protein expression, and mitochondrial dynamics.
10.3390/ijms27041638 · 2026 · External reference
Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
10.1107/s0907444913020507 · 2013 · External reference
A dimeric mutant of human pancreatic ribonuclease with selective cytotoxicity toward malignant cells
10.1073/pnas.96.14.7768 · 1999 · External reference
The dual-mode quaternary structure of seminal RNase
1992 · External reference
A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin
10.1016/j.jinorgbio.2017.05.005 · 2017 · External reference
Platinated oligomers of bovine pancreatic ribonuclease: structure and stability
10.1016/j.jinorgbio.2015.02.011 · 2015 · External reference
Platinum-based drugs and proteins: reactivity and relevance to DNA adduct formation
10.1016/j.jinorgbio.2013.01.007 · 2013 · External reference
Glycoproteins of bovine pancreatic juice
1968 · External reference
The isolation of ribounclease B, a glycoprotein, from bovine pancreatic juice
10.1016/s0021-9258(18)81195-4 · 1963 · External reference
Mutation in the α-synuclein gene identified in families with Parkinson's disease
10.1126/science.276.5321.2045 · 1997 · External reference
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells
10.1016/j.bcp.2019.06.006 · 2019 · External reference
Onconase restores cytotoxicity in dabrafenib-resistant A375 human melanoma cells and affects cell migration, invasion and colony formation capability
10.3390/ijms20235980 · 2019 · External reference
Ribonuclease A
10.1021/cr960427h · 1998 · External reference
Consequences of the endogenous N-glycosylation of human ribonuclease 1
10.1021/acs.biochem.8b01246 · 2019 · External reference
Glutaraldehyde as a protein cross-linking reagent
10.1016/0022-2836(68)90086-7 · 1968 · External reference
The preparation of subtilisn-modified ribonuclease and the separation of the peptide and protein components
10.1016/s0021-9258(18)70031-8 · 1959 · External reference
Intracellular pathway of onconase that enables its delivery to the cytosol
10.1242/jcs.03427 · 2007 · External reference
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
10.1038/362059a0 · 1993 · External reference
Recombinant human eosinophil cationic protein: ribonuclease activity is not essential for cytotoxicity
10.1074/jbc.270.14.7876 · 1995 · External reference
In vitro evolution of a dimeric variant of human pancreatic ribonuclease
10.1021/bi992367q · 2000 · External reference
Antitumor activity of ribonuclease multimers created by site-specific covalent tethering
10.1021/bc100292x · 2010 · External reference
Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity
10.2174/138920108784567344 · 2008 · External reference
Enhancement of vincristine cytotoxicity in drug-resistant cells by simultaneous treatment with onconase, an antitumor ribonuclease
10.1093/jnci/88.11.747 · 1996 · External reference
Amyloid-like fibrils of ribonuclease a with three-dimensional domain-swapped and native-like structure
10.1038/nature03916 · 2005 · External reference
Atomic structures of amyloid cross-β spines reveal varied steric zippers
10.1038/nature05695 · 2007 · External reference
Angiogenin is a cytotoxic, tRNA-specific ribonuclease in the RNase A superfamily
10.1016/s0021-9258(19)36710-9 · 1992 · External reference
Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. alanine derivatives inhibit angiogenin-induced angiogenesis
10.1021/bi00444a038 · 1989 · External reference
Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small-cell lung carcinoma and malignant mesothelioma
10.1093/abbs/gmw082 · 2016 · External reference
The multiple forms of bovine seminal ribonuclease: structure and stability of a C-terminal swapped dimer
10.1016/j.febslet.2013.10.003 · 2013 · External reference
Structure of angiogenin dimer bound to double-stranded RNA
10.1107/s2053230x22008317 · 2022 · External reference
A novel cross-linked RNase A dimer with enhanced enzymatic properties
10.1002/prot.21144 · 2007 · External reference
Sugar osmolyte inhibits and attenuates the fibrillogenesis in RNase A: an in vitro and in silico characterizations
2023 · External reference
Motoneurons secrete angiogenin to induce RNA cleavage in astroglia
10.1523/jneurosci.6366-11.2012 · 2012 · External reference
Genetic selection for critical residues in ribonucleases
10.1016/j.jmb.2006.07.020 · 2006 · External reference
The sequence of amino acid residues in bovine pancreatic ribonuclease: revisions and confirmations
10.1016/s0021-9258(19)83984-4 · 1963 · External reference
Carrier protein-modulated presentation and recognition of an N-glycan: observations on the interactions of Man8 glycoform of ribonuclease B with conglutinin
10.1093/glycob/11.1.31 · 2001 · External reference
Human pancreatic-type and nonpancreatic-type ribonucleases: a direct side-by-side comparison of their catalytic properties
10.1006/abbi.1994.1318 · 1994 · External reference
Human extracellular ribonucleases: multiplicity, molecular diversity and catalytic properties of the major RNase types
10.1007/s000180050207 · 1998 · External reference
The eight human "canonical" ribonucleases: molecular diversity, catalytic properties, and special biological actions of the enzyme proteins
10.1016/j.febslet.2010.04.018 · 2010 · External reference
The angiogenins
10.1007/s000180050210 · 1998 · External reference
Onconase action on tRNALys3, the primer for HIV-1 reverse transcription
10.1016/j.bbrc.2007.08.157 · 2007 · External reference
Contribution of electrostatics to the binding of pancreatic-type ribonucleases to membranes
10.1021/bi400619m · 2013 · External reference
Complete amino-acid sequence of bovine seminal ribonuclease, a dimeric protein from seminal plasma
10.1515/bchm3.1987.368.2.1305 · 1987 · External reference
Comparison of antitumor activities of pancreatic ribonuclease and its cross-linked dimer
1976 · External reference
Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation
10.1002/pro.754 · 2012 · External reference
Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor
10.1261/rna.065516.117 · 2018 · External reference
Value of general acid-base catalysis to ribonuclease A
10.1021/ja00091a060 · 1994 · External reference
Amino acid sequence of sialic acid binding lectin from frog (Rana catesbeiana) eggs
10.1021/bi00382a018 · 1987 · External reference
Eosinophil cationic protein aggregation: identification of an N-terminus amyloid prone region
10.1021/bm100334u · 2010 · External reference
Interaction of onconase with the human ribonuclease inhibitor protein
10.1016/j.bbrc.2008.10.032 · 2008 · External reference
Isoelectric points and conformation of proteins
1971 · External reference
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
10.1002/ana.22611 · 2011 · External reference
Reversible nephrotoxicity of onconase and effect of lysine pH on renal onconase uptake
10.1007/s002800050962 · 1999 · External reference
Eosinophil cationic protein (ECP)
10.1016/s1357-2725(97)00127-1 · 1998 · External reference
'Alessio, In vitro studies on selective inhibition of tumor cell growth by seminal ribonuclease
1980 · External reference
A phase II trial of weekly intravenous ranpirnase (Onconase®), a novel ribonuclease in patients with metastatic kidney cancer
10.1023/a:1010633004157 · 2001 · External reference
Zero-Length dimers of ribonuclease a: further characterization and no evidence of cytotoxicity
10.1021/bc900407v · 2010 · External reference
RNase A oligomerization through 3D domain swapping is favoured by a residue located far from the swapping domains
10.1016/j.biochi.2011.07.005 · 2011 · External reference
Polyspermine-ribonuclease prepared by cross-linkage with dimethyl suberimidate
10.1021/bi00632a021 · 1977 · External reference
Preparation of cross-linked dimers of pancreatic ribonuclease
10.1021/bi00648a033 · 1976 · External reference
Rosenthal fibers, eosinophilic inclusions, and anchorage densities with desmosome-like structures in astrocytes in Alzheimer's disease
10.1007/bf00313604 · 1994 · External reference
Two distinct secretory ribonucleases from human cerebrum: purification, characterization and relationships to other ribonucleases
10.1042/bj2960617 · 1993 · External reference
Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
10.1002/ana.22611 · ExternalCitation · doi-reference
Elucidation of the ribonuclease a aggregation process mediated by 3D domain swapping: a computational approach reveals possible new multimeric structures
10.1002/bip.20833 · ExternalCitation · doi-reference
Comparison of the structural and functional properties of RNase A and BS-RNase: a stepwise mutagenesis approach
10.1002/bip.21176 · ExternalCitation · doi-reference
3D domain swapping: a mechanism for oligomer assembly
10.1002/pro.5560041202 · ExternalCitation · doi-reference
Ribonuclease A suggests how proteins self-chaperone against amyloid fiber formation
10.1002/pro.754 · ExternalCitation · doi-reference
A novel cross-linked RNase A dimer with enhanced enzymatic properties
10.1002/prot.21144 · ExternalCitation · doi-reference
Human pancreatic-type and nonpancreatic-type ribonucleases: a direct side-by-side comparison of their catalytic properties
10.1006/abbi.1994.1318 · ExternalCitation · doi-reference
Identification of the nucleolar targeting signal of human angiogenin
10.1006/bbrc.1994.2391 · ExternalCitation · doi-reference
A residue to residue hydrogen bond mediates the nucleotide specificity of ribonuclease A
10.1006/jmbi.1995.0500 · ExternalCitation · doi-reference
Mechanism of ribonuclease inhibition by ribonuclease inhibitor protein based on the crystal structure of its complex with ribonuclease A
10.1006/jmbi.1996.0694 · ExternalCitation · doi-reference
Revisiting the action of bovine ribonuclease A and pancreatic-type ribonucleases on double-stranded RNA
10.1007/bf00230753 · ExternalCitation · doi-reference
Rosenthal fibers, eosinophilic inclusions, and anchorage densities with desmosome-like structures in astrocytes in Alzheimer's disease
10.1007/bf00313604 · ExternalCitation · doi-reference
Human extracellular ribonucleases: multiplicity, molecular diversity and catalytic properties of the major RNase types
10.1007/s000180050207 · ExternalCitation · doi-reference
The angiogenins
10.1007/s000180050210 · ExternalCitation · doi-reference
Reversible nephrotoxicity of onconase and effect of lysine pH on renal onconase uptake
10.1007/s002800050962 · ExternalCitation · doi-reference
Surface-exposed amino acids of eosinophil cationic protein play a critical role in the inhibition of mammalian cell proliferation
10.1007/s11010-005-4777-2 · ExternalCitation · doi-reference
The amino acid sequence of human pancreatic ribonuclease
10.1016/0003-2697(84)90306-3 · ExternalCitation · doi-reference
Cross-linking of α-chymotrypsin and other proteins by reaction with glutaraldehyde
10.1016/0003-9861(71)90492-9 · ExternalCitation · doi-reference
Purification and characterization of three ribonucleases from human kidney: comparison with urine ribonucleases
10.1016/0003-9861(90)90424-w · ExternalCitation · doi-reference
Dimeric structure of seminal ribonuclease
10.1016/0014-5793(72)80642-2 · ExternalCitation · doi-reference
The antitumor action of seminal ribonuclease and its quaternary conformations
10.1016/0014-5793(94)01450-f · ExternalCitation · doi-reference
Glutaraldehyde as a protein cross-linking reagent
10.1016/0022-2836(68)90086-7 · ExternalCitation · doi-reference
Bovine pancreatic ribonuclease A as a model of an enzyme with multiple substrate binding sites
10.1016/0167-4838(95)00138-k · ExternalCitation · doi-reference
Specific effect of bull seminal ribonuclease (AS RNase) on cell systems in mice
10.1016/0300-9629(73)90415-5 · ExternalCitation · doi-reference
Kinetic analysis provides insight into the mechanism of Ribonuclease A oligomer formation
10.1016/j.abb.2009.07.013 · ExternalCitation · doi-reference
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells
10.1016/j.bbamcr.2014.01.025 · ExternalCitation · doi-reference
Onconase induces autophagy sensitizing pancreatic cancer cells to gemcitabine and activates Akt/mTOR pathway in a ROS-dependent manner
10.1016/j.bbamcr.2014.12.016 · ExternalCitation · doi-reference
Three-dimensional domain-swapped oligomers of ribonuclease A: identification of a fifth tetramer, pentamers and hexamers, and detection of trace heptameric, octameric and nonameric species
10.1016/j.bbapap.2005.10.011 · ExternalCitation · doi-reference
Extensive deamidation of RNase A inhibits its oligomerization through 3D domain swapping
10.1016/j.bbapap.2016.10.008 · ExternalCitation · doi-reference
Onconase action on tRNALys3, the primer for HIV-1 reverse transcription
10.1016/j.bbrc.2007.08.157 · ExternalCitation · doi-reference
Interaction of onconase with the human ribonuclease inhibitor protein
10.1016/j.bbrc.2008.10.032 · ExternalCitation · doi-reference
Influence of onconase in the therapeutic potential of PARP inhibitors in A375 malignant melanoma cells
10.1016/j.bcp.2019.06.006 · ExternalCitation · doi-reference
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Human RNase 1 can extensively oligomerize through 3D domain swapping thanks to the crucial contribution of its C-terminus
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Angiogenin is a cytotoxic, tRNA-specific ribonuclease in the RNase A superfamily
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Cytotoxicity and binding to DNA, lysozyme, ribonuclease a, and human serum albumin of the diiodido analog of picoplatin
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Polyspermine-ribonuclease prepared by cross-linkage with dimethyl suberimidate
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