Research graph
References from The thyroid hormone drives bidirectional communication along the brain-gut axis in vertebrate models. Local targets link to admitted publications; unresolved targets remain external evidence.
Effects of experimentally induced hypothyroidism and hyperthyroidism on the development of the rat cerebellar cortex
2008 · External reference
The gut-brain axis: Influence of microbiota on mood and mental health
2018 · External reference
Cortisol inhibits thyroidal activity and modifies hydromineral balance in the freshwater fish Clarias gariepinus
2010 · External reference
The thyroid–brain interaction in thyroid disorders and mood disorders
10.1111/j.1365-2826.2008.01774.x · 2008 · External reference
Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota
2016 · External reference
Thyroid hormones, serotonin and mood: Of synergy and significance in the adult brain
10.1038/sj.mp.4000963 · 2002 · External reference
Thyroid hormone transporters—Functions and clinical implications
10.1038/nrendo.2015.66 · 2015 · External reference
Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression
10.1371/journal.pgen.0030188 · 2007 · External reference
Deiodinases: Implications of the local control of thyroid hormone action
10.1172/jci29812 · 2006 · External reference
The vagus nerve at the interface of the microbiota-gut-brain axis
10.3389/fnins.2018.00049 · 2018 · External reference
Microbiota and neurodevelopmental windows: Implications for brain disorders
10.1016/j.molmed.2014.05.002 · 2014 · External reference
Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders
10.3389/fpsyt.2018.00044 · 2018 · External reference
Unresolved reference
2005 · External reference
The gut–brain axis: Interactions between enteric microbiota, central and enteric nervous systems
2015 · External reference
Musings on the wanderer: What's new in our understanding of vago-vagal reflex? IV. Current concepts of vagal efferent projections to the gut
10.1152/ajpgi.00478.2002 · 2003 · External reference
Thyroid hormone action in cerebellum and cerebral cortex development
10.4061/2011/145762 · 2011 · External reference
Molecular aspects of thyroid hormone actions
10.1210/er.2009-0007 · 2010 · External reference
Iodothyronine deiodinase structure and function: From ascidians to humans
10.1530/joe-12-0204 · 2012 · External reference
Thyroid function and serotonin transporter binding in the human hypothalamus and midbrain: A PET study
2015 · External reference
The role of the thyroid axis in fish
10.3389/fendo.2020.596585 · 2020 · External reference
Transport of iodothyronines from bloodstream to brain: Contributions by blood-brain and choroid plexus–cerebrospinal fluid barriers
10.1016/0006-8993(91)90194-z · 1991 · External reference
Negative feedback regulation of hypophysiotropic thyrotropin-releasing hormone (TRH) neurons: Role of neuronal afferents and type 2 deiodinase
2014 · External reference
Stress & the gut–brain axis: Regulation by the microbiome
10.1016/j.ynstr.2017.03.001 · 2017 · External reference
Thyroid hormones and cholinergic function
1989 · External reference
Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10
10.1210/me.2007-0112 · 2008 · External reference
The enteric nervous system and neurogastroenterology
10.1038/nrgastro.2012.32 · 2012 · External reference
The hypothalamic-pituitary-thyroid axis
2019 · External reference
Environmental and endocrinological control of osmoregulation in teleosts
1988 · External reference
Thyroid hormone transporters
10.1210/endrev/bnz008 · 2019 · External reference
Expression of type 2 iodothyronine deiodinase in hypothyroid rat brain indicates an important role of thyroid hormone in the development of specific primary sensory systems
10.1523/jneurosci.19-09-03430.1999 · 1999 · External reference
Unresolved reference
2009 · External reference
Localization of human thyroxine absorption
1999 · External reference
The xenoestrogen bisphenol a inhibits postembryonic development by antagonizing gene regulation by thyroid hormone
10.1210/en.2008-1503 · 2010 · External reference
Paraventricular hypothalamic mechanisms of chronic stress adaptation
10.3389/fendo.2016.00137 · 2016 · External reference
The importance of thyroid hormone transporters for brain development and function
10.1016/j.beem.2007.03.003 · 2007 · External reference
Neuropeptides and the microbiota–gut–brain axis
10.1007/978-1-4939-0897-4_9 · 2014 · External reference
The neuro-symphony of stress
10.1038/nrn2632 · 2009 · External reference
Unresolved reference
2013 · External reference
cDNA cloning of thyroid hormone receptor betas from the conger eel, Conger myriaster
10.1016/s0016-6480(02)00638-x · 2003 · External reference
Thyroid-gut-axis: How does the microbiota influence thyroid function?
10.3390/nu12061769 · 2020 · External reference
Thyroid hormone action in the central nervous system
2005 · External reference
Stress and the gut: Pathophysiology, clinical consequences, diagnostic approach and treatment options
2011 · External reference
The thyroid hormone receptor α1 directly controls transcription of the β-catenin gene in intestinal epithelial cells
2009 · External reference
Thyroid hormone receptors: Multiple forms, multiple possibilities
1993 · External reference
Stress at the intestinal surface: Catecholamines and mucosa–bacteria interactions
10.1007/s00441-010-1050-0 · 2011 · External reference
The neurobiology of anxiety disorders: Brain imaging, genetics, and psychoneuroendocrinology
10.1016/j.psc.2009.05.004 · 2018 · External reference
The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction
10.1002/glia.20990 · 2010 · External reference
Gut feelings: The emerging biology of gut-brain communication
10.1038/nrn3071 · 2011 · External reference
Gut microbes and the brain: Paradigm shift in neuroscience
10.1523/jneurosci.3299-14.2014 · 2014 · External reference
Thyroid hormone signaling in energy homeostasis and energy metabolism
10.1111/nyas.12374 · 2014 · External reference
Physiology and neurobiology of stress and adaptation: Central role of the brain
10.1152/physrev.00041.2006 · 2007 · External reference
Metamorphosis in teleosts
10.1016/b978-0-12-385979-2.00005-8 · 2013 · External reference
Thyroid hormone–induced swim bladder and eye maturation are transduced by IGF-1 in zebrafish embryos
10.1111/are.14305 · 2019 · External reference
Influence of thyroid status on nitric oxide synthase activity and protein nitration in rat gastric mucosa
2011 · External reference
Brain–gut–microbiota axis in Parkinson's disease
10.3748/wjg.v21.i37.10609 · 2015 · External reference
Intermittent restraint stress and recovery on GPCR expression in brain/gut axis of mice: Activation of adrenergic, dopamine, serotonin and melatonin receptors during stress and ease response
2024 · External reference
Thyroid receptor subtypes: Structure and function in fish
10.1016/j.ygcen.2008.09.006 · 2009 · External reference
Binding of thyroxine and triiodothyronine by intestinal bacteria
1993 · External reference
5′- and 5-deiodinase activities in adult rat cecum and large bowel contents inhibited by intestinal microflora
10.1152/ajpendo.1993.265.3.e521 · 1993 · External reference
The development and general morphology of the telencephalon of actinopterygian fishes: Synopsis, documentation and commentary
10.1007/s00429-010-0285-6 · 2011 · External reference
Understanding vertebrate brain evolution
10.1093/icb/42.4.743 · 2002 · External reference
Thyroid hormone deiodination in fish
10.1089/thy.2005.15.799 · 2005 · External reference
Thyroid hormone and estrogen regulate brain region–specific messenger ribonucleic acids encoding three gonadotropin–releasing hormone genes in sexually immature male fish, Oreochromis niloticus
10.1210/endo.141.5.7460 · 2000 · External reference
Unresolved reference
2007 · External reference
Stress response in Mozambique tilapia (Oreochromis mossambicus): Temporal and inverse interaction of cortisol and thyroid hormone when confined to net
2009 · External reference
The role of thyroid hormones in stress response of fish
10.1016/j.ygcen.2011.02.023 · 2011 · External reference
Metabolic and thyroidal response in air-breathing perch (Anabas testudineus) to water-borne kerosene
10.1016/j.ygcen.2007.05.015 · 2007 · External reference
Evidence for an osmoregulatory role of thyroid hormones in the freshwater mozambique tilapia Oreochromis mossambicus
10.1006/gcen.2000.7542 · 2000 · External reference
Ionoregulatory and interrenal responses in hyper- and hypothyroid tilapia (Oreochromis mossambicus) to thyroid hormones
2006 · External reference
Thyroid hormones in growth and development of fish
2000 · External reference
Thyroid hormones in growth and development of fish
2001 · External reference
Stress-induced enhancement of fear learning: An animal model of posttraumatic stress disorder
10.1016/j.neubiorev.2005.04.010 · 2005 · External reference
Epithelium-associated bacteria in the gastrointestinal tract of arctic charr (Salvelinus alpinus L.). an electron microscopical study
2003 · External reference
Thyroxine-thyroid hormone receptor interactions
10.1074/jbc.m410124200 · 2004 · External reference
Radioiodine and the treatment of hyperthyroidism: The early history
10.1089/thy.1997.7.163 · 1997 · External reference
The human enteric nervous system
10.1111/j.1743-3150.2004.00476.x · 2004 · External reference
Minireview: Defining the roles of the iodothyronine deiodinases: Current concepts and challenges
10.1210/en.2008-1588 · 2009 · External reference
Effects of L-NAME and air exposure on mitochondrial energetic markers, thyroid hormone receptor/regulator system and stress/ease-responsive receptor expression in the brain/gut axis of zebrafish
2024 · External reference
Prenatal hypothyroidism alters expression of NMDA receptor subunits and impairs long-term potentiation in rat hippocampus
2012 · External reference
Role of corticotropin-releasing factor pathways in stress-related alterations of colonic function
2009 · External reference
An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor α
10.1016/j.ygcen.2007.04.012 · 2008 · External reference
Stress responses: From physiology to disease
2023 · External reference
Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress
10.1016/s0022-3999(02)00429-4 · 2002 · External reference
Zebrafish as a model for monocarboxyl transporter 8–deficiency
10.1074/jbc.m112.413831 · 2013 · External reference
Cortisol treatment affects glucocorticoid receptor and glucocorticoid-responsive genes in the liver of rainbow trout
10.1016/s0016-6480(03)00092-3 · 2003 · External reference
Gut microbiota and thyroid interaction in health and disease
10.1007/s11154-018-9467-y · 2018 · External reference
Gut microbiota and hashimoto's thyroiditis
10.1007/s11154-018-9467-y · 2018 · External reference
Minireview: Thyroid hormone transporters: The knowns and the unknowns
10.1210/me.2010-0095 · 2011 · External reference
Thyroid hormones activate TH/E₂ receptor/regulator system and drive Na+/K+-ATPase in the ovarian wall of hypothyroid air-breathing fish (Anabas testudineus)
10.1016/j.ygcen.2024.114640 · 2025 · External reference
The neuroendocrine regulation of food intake in fish: A review of current knowledge
10.3389/fnins.2016.00540 · 2016 · External reference
The thyroid hormone receptor alpha1protein is expressed in embryonic post-mitotic neurons and persists in most adult neurons
10.1210/me.2010-0175 · 2010 · External reference
Unresolved reference
2003 · External reference
The perivascular astroglial sheath provides a complete covering of the brain microvessels: An electron microscopic 3D reconstruction
10.1002/glia.20990 · ExternalCitation · doi-reference
Evidence for an osmoregulatory role of thyroid hormones in the freshwater mozambique tilapia Oreochromis mossambicus
10.1006/gcen.2000.7542 · ExternalCitation · doi-reference
Neuropeptides and the microbiota–gut–brain axis
10.1007/978-1-4939-0897-4_9 · ExternalCitation · doi-reference
The development and general morphology of the telencephalon of actinopterygian fishes: Synopsis, documentation and commentary
10.1007/s00429-010-0285-6 · ExternalCitation · doi-reference
Stress at the intestinal surface: Catecholamines and mucosa–bacteria interactions
10.1007/s00441-010-1050-0 · ExternalCitation · doi-reference
Gut microbiota and hashimoto's thyroiditis
10.1007/s11154-018-9467-y · ExternalCitation · doi-reference
Transport of iodothyronines from bloodstream to brain: Contributions by blood-brain and choroid plexus–cerebrospinal fluid barriers
10.1016/0006-8993(91)90194-z · ExternalCitation · doi-reference
Metamorphosis in teleosts
10.1016/b978-0-12-385979-2.00005-8 · ExternalCitation · doi-reference
The importance of thyroid hormone transporters for brain development and function
10.1016/j.beem.2007.03.003 · ExternalCitation · doi-reference
Microbiota and neurodevelopmental windows: Implications for brain disorders
10.1016/j.molmed.2014.05.002 · ExternalCitation · doi-reference
Stress-induced enhancement of fear learning: An animal model of posttraumatic stress disorder
10.1016/j.neubiorev.2005.04.010 · ExternalCitation · doi-reference
The neurobiology of anxiety disorders: Brain imaging, genetics, and psychoneuroendocrinology
10.1016/j.psc.2009.05.004 · ExternalCitation · doi-reference
An F-domain introduced by alternative splicing regulates activity of the zebrafish thyroid hormone receptor α
10.1016/j.ygcen.2007.04.012 · ExternalCitation · doi-reference
Metabolic and thyroidal response in air-breathing perch (Anabas testudineus) to water-borne kerosene
10.1016/j.ygcen.2007.05.015 · ExternalCitation · doi-reference
Thyroid receptor subtypes: Structure and function in fish
10.1016/j.ygcen.2008.09.006 · ExternalCitation · doi-reference
The role of thyroid hormones in stress response of fish
10.1016/j.ygcen.2011.02.023 · ExternalCitation · doi-reference
Thyroid hormones activate TH/E₂ receptor/regulator system and drive Na+/K+-ATPase in the ovarian wall of hypothyroid air-breathing fish (Anabas testudineus)
10.1016/j.ygcen.2024.114640 · ExternalCitation · doi-reference
Stress & the gut–brain axis: Regulation by the microbiome
10.1016/j.ynstr.2017.03.001 · ExternalCitation · doi-reference
cDNA cloning of thyroid hormone receptor betas from the conger eel, Conger myriaster
10.1016/s0016-6480(02)00638-x · ExternalCitation · doi-reference
Cortisol treatment affects glucocorticoid receptor and glucocorticoid-responsive genes in the liver of rainbow trout
10.1016/s0016-6480(03)00092-3 · ExternalCitation · doi-reference
Hypothalamic–pituitary–adrenal axis, neuroendocrine factors and stress
10.1016/s0022-3999(02)00429-4 · ExternalCitation · doi-reference
Thyroid hormone transporters—Functions and clinical implications
10.1038/nrendo.2015.66 · ExternalCitation · doi-reference
The enteric nervous system and neurogastroenterology
10.1038/nrgastro.2012.32 · ExternalCitation · doi-reference
The neuro-symphony of stress
10.1038/nrn2632 · ExternalCitation · doi-reference
Gut feelings: The emerging biology of gut-brain communication
10.1038/nrn3071 · ExternalCitation · doi-reference
Thyroid hormones, serotonin and mood: Of synergy and significance in the adult brain
10.1038/sj.mp.4000963 · ExternalCitation · doi-reference
Zebrafish as a model for monocarboxyl transporter 8–deficiency
10.1074/jbc.m112.413831 · ExternalCitation · doi-reference
Thyroxine-thyroid hormone receptor interactions
10.1074/jbc.m410124200 · ExternalCitation · doi-reference
Radioiodine and the treatment of hyperthyroidism: The early history
10.1089/thy.1997.7.163 · ExternalCitation · doi-reference
Thyroid hormone deiodination in fish
10.1089/thy.2005.15.799 · ExternalCitation · doi-reference
Understanding vertebrate brain evolution
10.1093/icb/42.4.743 · ExternalCitation · doi-reference
Thyroid hormone–induced swim bladder and eye maturation are transduced by IGF-1 in zebrafish embryos
10.1111/are.14305 · ExternalCitation · doi-reference
The thyroid–brain interaction in thyroid disorders and mood disorders
10.1111/j.1365-2826.2008.01774.x · ExternalCitation · doi-reference
The human enteric nervous system
10.1111/j.1743-3150.2004.00476.x · ExternalCitation · doi-reference
Thyroid hormone signaling in energy homeostasis and energy metabolism
10.1111/nyas.12374 · ExternalCitation · doi-reference
5′- and 5-deiodinase activities in adult rat cecum and large bowel contents inhibited by intestinal microflora
10.1152/ajpendo.1993.265.3.e521 · ExternalCitation · doi-reference
Musings on the wanderer: What's new in our understanding of vago-vagal reflex? IV. Current concepts of vagal efferent projections to the gut
10.1152/ajpgi.00478.2002 · ExternalCitation · doi-reference
Physiology and neurobiology of stress and adaptation: Central role of the brain
10.1152/physrev.00041.2006 · ExternalCitation · doi-reference
Deiodinases: Implications of the local control of thyroid hormone action
10.1172/jci29812 · ExternalCitation · doi-reference
The xenoestrogen bisphenol a inhibits postembryonic development by antagonizing gene regulation by thyroid hormone
10.1210/en.2008-1503 · ExternalCitation · doi-reference
Minireview: Defining the roles of the iodothyronine deiodinases: Current concepts and challenges
10.1210/en.2008-1588 · ExternalCitation · doi-reference
Thyroid hormone and estrogen regulate brain region–specific messenger ribonucleic acids encoding three gonadotropin–releasing hormone genes in sexually immature male fish, Oreochromis niloticus
10.1210/endo.141.5.7460 · ExternalCitation · doi-reference
Thyroid hormone transporters
10.1210/endrev/bnz008 · ExternalCitation · doi-reference
Molecular aspects of thyroid hormone actions
10.1210/er.2009-0007 · ExternalCitation · doi-reference
Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10
10.1210/me.2007-0112 · ExternalCitation · doi-reference
Minireview: Thyroid hormone transporters: The knowns and the unknowns
10.1210/me.2010-0095 · ExternalCitation · doi-reference
The thyroid hormone receptor alpha1protein is expressed in embryonic post-mitotic neurons and persists in most adult neurons
10.1210/me.2010-0175 · ExternalCitation · doi-reference
Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression
10.1371/journal.pgen.0030188 · ExternalCitation · doi-reference
Expression of type 2 iodothyronine deiodinase in hypothyroid rat brain indicates an important role of thyroid hormone in the development of specific primary sensory systems
10.1523/jneurosci.19-09-03430.1999 · ExternalCitation · doi-reference
Gut microbes and the brain: Paradigm shift in neuroscience
10.1523/jneurosci.3299-14.2014 · ExternalCitation · doi-reference
Iodothyronine deiodinase structure and function: From ascidians to humans
10.1530/joe-12-0204 · ExternalCitation · doi-reference
Paraventricular hypothalamic mechanisms of chronic stress adaptation
10.3389/fendo.2016.00137 · ExternalCitation · doi-reference
The role of the thyroid axis in fish
10.3389/fendo.2020.596585 · ExternalCitation · doi-reference
The neuroendocrine regulation of food intake in fish: A review of current knowledge
10.3389/fnins.2016.00540 · ExternalCitation · doi-reference
The vagus nerve at the interface of the microbiota-gut-brain axis
10.3389/fnins.2018.00049 · ExternalCitation · doi-reference
Vagus nerve as modulator of the brain–gut axis in psychiatric and inflammatory disorders
10.3389/fpsyt.2018.00044 · ExternalCitation · doi-reference
Thyroid-gut-axis: How does the microbiota influence thyroid function?
10.3390/nu12061769 · ExternalCitation · doi-reference
Brain–gut–microbiota axis in Parkinson's disease
10.3748/wjg.v21.i37.10609 · ExternalCitation · doi-reference
Thyroid hormone action in cerebellum and cerebral cortex development
10.4061/2011/145762 · ExternalCitation · doi-reference
