Research graph
References from The thyroid–brain axis in hyperthyroidism: Neurotoxic mechanisms and nutraceutical interventions. Local targets link to admitted publications; unresolved targets remain external evidence.
The association of thyroid disease with risk of dementia and cognitive impairment: A systematic review
10.3390/medicina60121917 · 2024 · External reference
How thyroid hormone disorder affect the expression of genes related to neurodegeneration in the hippocampus tissue of rats: An experimental study
10.4103/jcls.jcls_34_24 · 2024 · External reference
Neuroprotective efficacy and complementary treatment with medicinal herbs: A comprehensive review of recent therapeutic approaches in epilepsy management
10.2174/0118715273332140240724093837 · 2025 · External reference
Antioxidant metabolism pathways in vitamins, polyphenols, and selenium: Parallels and divergences
10.3390/ijms25052600 · 2024 · External reference
The potency of ginkgo biloba in treating tinnitus: A review
10.37275/ehi.v3i2.34 · 2021 · External reference
Involvement of integrin αvβ3 in thyroid hormone-induced dendritogenesis
10.3389/fendo.2022.938596 · 2022 · External reference
Interaction of mitochondrial calcium and ROS in neurodegeneration
10.3390/cells11040706 · 2022 · External reference
Neuroprotective effects of coenzyme Q10 on neurological diseases: A review article
2023 · External reference
Attenuation of hypothyroidism-induced cognitive impairment by modulating serotonin mediation
10.3390/vetsci10020122 · 2023 · External reference
Relationship between mood disorders and thyroid changes
10.36557/2674-8169.2024v6n2p2241-2256 · 2024 · External reference
Exploring the role of phytoconstituents for endocrine disorder: A review
10.5530/pres.20252070 · 2025 · External reference
Association between small intestine bacterial overgrowth and psychiatric disorders
10.3389/fendo.2024.1438066 · 2024 · External reference
Effects of trace elements on endocrine function and pathogenesis of thyroid diseases—A literature review
10.3390/nu17030398 · 2025 · External reference
Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction
10.1111/jnc.16124 · 2024 · External reference
Association between thyroid hormones and insulin resistance indices based on the Korean national health and nutrition examination survey
2021 · External reference
Essentiality, relevance, and efficacy of adjuvant/combinational therapy in the management of thyroid dysfunctions
10.1016/j.biopha.2022.112613 · 2022 · External reference
Vulnerability of the hippocampus to insults: Links to blood–brain barrier dysfunction
10.3390/ijms25041991 · 2024 · External reference
Association between subclinical thyroid dysfunction and fracture risk
10.1001/jamanetworkopen.2022.40823 · 2022 · External reference
Neonatal thyrotoxicosis with tricuspid valve regurgitation and hydrops in a preterm infant born to a mother with graves' disease
10.1055/s-0038-1645879 · 2018 · External reference
The impact of hypoxia on blood-brain, blood-CSF, and CSF-brain barriers
10.1152/japplphysiol.00108.2020 · 2021 · External reference
Postischemic neuroprotection of aminoethoxydiphenyl borate associates shortening of peri-infarct depolarizations
10.3390/ijms23137449 · 2022 · External reference
Thyroid hormone receptors function in GABAergic neurons during development and in adults
10.1210/endocr/bqae101 · 2024 · External reference
Curcumin and ferroptosis: A promising target for disease prevention and treatment
10.1007/s12013-023-01212-6 · 2024 · External reference
How do intestinal probiotics restore the intestinal barrier?
10.3389/fmicb.2022.929346 · 2022 · External reference
Neurodevelopmental Follow-Up of children born to mothers with graves' disease and neonatal hyperthyroidism
2024 · External reference
The role of glutamate and blood–brain barrier disruption as a mechanistic link between epilepsy and depression
10.3390/cells13141228 · 2024 · External reference
Breaking the barrier: The role of proinflammatory cytokines in BBB dysfunction
10.3390/ijms26083532 · 2025 · External reference
Beyond the GFAP-astrocyte protein markers in the brain
10.3390/biom11091361 · 2021 · External reference
Beyond thyroid dysfunction: The systemic impact of iodine excess
10.3389/fendo.2025.1568807 · 2025 · External reference
Congenital hypothyroidism in preterm newborns – The challenges of diagnostics and treatment: A review
10.3389/fendo.2022.860862 · 2022 · External reference
The influence of oxidative stress on thyroid diseases
10.3390/antiox10091442 · 2021 · External reference
Synthesis and significance of arachidonic acid, a substrate for cyclooxygenases, lipoxygenases, and cytochrome P450 pathways in the tumorigenesis of glioblastoma multiforme, including a pan-cancer comparative analysis
10.3390/cancers15030946 · 2023 · External reference
Oxidative stress, mitochondrial dysfunction, and neuroprotection of polyphenols with respect to resveratrol in parkinson's disease
10.3390/biomedicines9080918 · 2021 · External reference
Thyroid dysfunction and alzheimer's disease, a vicious circle
2024 · External reference
Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: A resting-state functional MRI study
10.18632/oncotarget.14060 · 2017 · External reference
High prevalence of erectile dysfunction in men with hyperthyroidism: A meta-analysis
10.1186/s12902-024-01585-6 · 2024 · External reference
The effect of hyperthyroidism on cognitive function, neuroinflammation, and necroptosis in APP/PS1 mice
10.1186/s12967-023-04511-x · 2023 · External reference
Application progress of artificial intelligence in managing thyroid disease
10.3389/fendo.2025.1578455 · 2025 · External reference
The protective role of nutritional antioxidants against oxidative stress in thyroid disorders
10.3389/fendo.2022.1092837 · 2023 · External reference
Melatonin and vitamin C modulate cassava diet-induced alteration in reproductive and thyroid functions
10.4103/njecp.njecp_9_21 · 2021 · External reference
Coenzyme Q10 and endocrine disorders: An overview
10.3390/antiox12020514 · 2023 · External reference
Ketamine and zinc: Treatment of anorexia nervosa via dual NMDA receptor modulation
10.1007/s40263-022-00984-4 · 2023 · External reference
Hyperthyroidism masquerading as an anxiety disorder: A report on a misdiagnosed case
2023 · External reference
Thyrotoxic periodic paralysis: A presentation of hyperthyroidism increasing in frequency around the world
10.1080/16089677.2023.2170955 · 2023 · External reference
Thyroid hormone action controls multiple components of cell junctions at the ventricular zone in the newborn rat brain
2023 · External reference
Neuroprotective effects of magnesium: Implications for neuroinflammation and cognitive decline
10.3389/fendo.2024.1406455 · 2024 · External reference
Coenzyme Q10 a mitochondrial restorer for various brain disorders
10.1007/s00210-021-02161-8 · 2021 · External reference
An integrative approach to HPA axis dysfunction: From recognition to recovery
10.1016/j.amjmed.2025.05.044 · 2025 · External reference
Autoimmune thyroid disorders: The mediterranean diet as a protective choice
10.3390/nu15183953 · 2023 · External reference
The potential role of thyroid hormone therapy in neural progenitor cell differentiation and its impact on neurodevelopmental disorders
10.1007/s12035-023-03751-8 · 2024 · External reference
Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions
10.1007/s43440-022-00377-w · 2022 · External reference
Insights into the molecular aspects of neuroprotective bacoside A and bacopaside I
10.2174/1570159x16666180419123022 · 2019 · External reference
Thyroid hormone supplementation restores cognitive deficit, insulin signaling, and neuroinflammation in the hippocampus of a sporadic alzheimer’s-like disease rat model
10.3390/cells13211793 · 2024 · External reference
N-Acetylcysteine and safranal prevented the brain damage induced by hyperthyroidism in adult male rats
10.1080/1028415x.2020.1743917 · 2022 · External reference
Cellular and molecular mechanisms of curcumin in thyroid gland disorders
10.2174/0929867329666220210145033 · 2022 · External reference
Effect of probiotics or prebiotics on thyroid function: A meta-analysis of eight randomized controlled trials
10.1371/journal.pone.0296733 · 2024 · External reference
Association of antioxidants in thyroid dysfunction
2024 · External reference
The hypothalamic–pituitary–adrenal and -thyroid axes activation lasting one year after an earthquake swarm: Results from a big data analysis
10.1007/s40618-020-01457-5 · 2021 · External reference
Measurement of oxidative stress and total antioxidant capacity in hyperthyroid patients following treatment with carbimazole and antioxidant
10.1016/j.heliyon.2021.e08651 · 2022 · External reference
Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury
10.1016/j.neuint.2023.105642 · 2024 · External reference
The therapeutic potential of propranolol and other beta-blockers in hyperthyroidism
10.3390/ijms26178322 · 2025 · External reference
Effect of L-thyroxine administration on long-term potentiation and accompanying mitogen-activated protein kinases in rats
10.1002/jdn.10097 · 2021 · External reference
Brain functional connectivity in hyperthyroid patients: Systematic review
10.3389/fnins.2024.1383355 · 2024 · External reference
Aquaporins as targets of dietary bioactive phytocompounds
10.3389/fmolb.2018.00030 · 2018 · External reference
Dietary sources of omega 3 fatty acids: Public health risks and benefits
10.1017/s0007114512001456 · 2012 · External reference
Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage
10.1530/etj-24-0143 · 2025 · External reference
Thyroid hormones and brain development: A focus on the role of mitochondria as regulators of developmental time
10.3390/cells14030150 · 2025 · External reference
Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway
10.1080/21655979.2022.2060626 · 2022 · External reference
Hyperthyroidism and liver dysfunction: A review of a common comorbidity
2022 · External reference
Pharmacological effects of polyphenol phytochemicals on the intestinal inflammation via targeting TLR4/NF-κB signaling pathway
10.3390/ijms23136939 · 2022 · External reference
Are probiotics, prebiotics, and synbiotics beneficial in primary thyroid diseases? A systematic review with meta-analysis
10.26444/aaem/162732 · 2023 · External reference
Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function
10.1016/j.nbd.2022.105807 · 2022 · External reference
Association between subclinical thyroid dysfunction and fracture risk
10.1001/jamanetworkopen.2022.40823 · ExternalCitation · doi-reference
Effect of L-thyroxine administration on long-term potentiation and accompanying mitogen-activated protein kinases in rats
10.1002/jdn.10097 · ExternalCitation · doi-reference
Coenzyme Q10 a mitochondrial restorer for various brain disorders
10.1007/s00210-021-02161-8 · ExternalCitation · doi-reference
Curcumin and ferroptosis: A promising target for disease prevention and treatment
10.1007/s12013-023-01212-6 · ExternalCitation · doi-reference
The potential role of thyroid hormone therapy in neural progenitor cell differentiation and its impact on neurodevelopmental disorders
10.1007/s12035-023-03751-8 · ExternalCitation · doi-reference
Ketamine and zinc: Treatment of anorexia nervosa via dual NMDA receptor modulation
10.1007/s40263-022-00984-4 · ExternalCitation · doi-reference
The hypothalamic–pituitary–adrenal and -thyroid axes activation lasting one year after an earthquake swarm: Results from a big data analysis
10.1007/s40618-020-01457-5 · ExternalCitation · doi-reference
Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions
10.1007/s43440-022-00377-w · ExternalCitation · doi-reference
An integrative approach to HPA axis dysfunction: From recognition to recovery
10.1016/j.amjmed.2025.05.044 · ExternalCitation · doi-reference
Essentiality, relevance, and efficacy of adjuvant/combinational therapy in the management of thyroid dysfunctions
10.1016/j.biopha.2022.112613 · ExternalCitation · doi-reference
Measurement of oxidative stress and total antioxidant capacity in hyperthyroid patients following treatment with carbimazole and antioxidant
10.1016/j.heliyon.2021.e08651 · ExternalCitation · doi-reference
Impaired learning and memory generated by hyperthyroidism is rescued by restoration of AMPA and NMDA receptors function
10.1016/j.nbd.2022.105807 · ExternalCitation · doi-reference
Matrix Metalloproteinase-9 inhibitors as therapeutic drugs for traumatic brain injury
10.1016/j.neuint.2023.105642 · ExternalCitation · doi-reference
Dietary sources of omega 3 fatty acids: Public health risks and benefits
10.1017/s0007114512001456 · ExternalCitation · doi-reference
Neonatal thyrotoxicosis with tricuspid valve regurgitation and hydrops in a preterm infant born to a mother with graves' disease
10.1055/s-0038-1645879 · ExternalCitation · doi-reference
N-Acetylcysteine and safranal prevented the brain damage induced by hyperthyroidism in adult male rats
10.1080/1028415x.2020.1743917 · ExternalCitation · doi-reference
Thyrotoxic periodic paralysis: A presentation of hyperthyroidism increasing in frequency around the world
10.1080/16089677.2023.2170955 · ExternalCitation · doi-reference
Role of sirtuin 1 in the brain development in congenital hypothyroidism rats via the regulation of p53 signaling pathway
10.1080/21655979.2022.2060626 · ExternalCitation · doi-reference
Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction
10.1111/jnc.16124 · ExternalCitation · doi-reference
The impact of hypoxia on blood-brain, blood-CSF, and CSF-brain barriers
10.1152/japplphysiol.00108.2020 · ExternalCitation · doi-reference
High prevalence of erectile dysfunction in men with hyperthyroidism: A meta-analysis
10.1186/s12902-024-01585-6 · ExternalCitation · doi-reference
The effect of hyperthyroidism on cognitive function, neuroinflammation, and necroptosis in APP/PS1 mice
10.1186/s12967-023-04511-x · ExternalCitation · doi-reference
Thyroid hormone receptors function in GABAergic neurons during development and in adults
10.1210/endocr/bqae101 · ExternalCitation · doi-reference
Effect of probiotics or prebiotics on thyroid function: A meta-analysis of eight randomized controlled trials
10.1371/journal.pone.0296733 · ExternalCitation · doi-reference
Triiodothyronine treatment in mice improves stroke outcome and reduces blood–brain barrier damage
10.1530/etj-24-0143 · ExternalCitation · doi-reference
Abnormal brain functional connectivity leads to impaired mood and cognition in hyperthyroidism: A resting-state functional MRI study
10.18632/oncotarget.14060 · ExternalCitation · doi-reference
Neuroprotective efficacy and complementary treatment with medicinal herbs: A comprehensive review of recent therapeutic approaches in epilepsy management
10.2174/0118715273332140240724093837 · ExternalCitation · doi-reference
Cellular and molecular mechanisms of curcumin in thyroid gland disorders
10.2174/0929867329666220210145033 · ExternalCitation · doi-reference
Insights into the molecular aspects of neuroprotective bacoside A and bacopaside I
10.2174/1570159x16666180419123022 · ExternalCitation · doi-reference
Are probiotics, prebiotics, and synbiotics beneficial in primary thyroid diseases? A systematic review with meta-analysis
10.26444/aaem/162732 · ExternalCitation · doi-reference
The protective role of nutritional antioxidants against oxidative stress in thyroid disorders
10.3389/fendo.2022.1092837 · ExternalCitation · doi-reference
Congenital hypothyroidism in preterm newborns – The challenges of diagnostics and treatment: A review
10.3389/fendo.2022.860862 · ExternalCitation · doi-reference
Involvement of integrin αvβ3 in thyroid hormone-induced dendritogenesis
10.3389/fendo.2022.938596 · ExternalCitation · doi-reference
Neuroprotective effects of magnesium: Implications for neuroinflammation and cognitive decline
10.3389/fendo.2024.1406455 · ExternalCitation · doi-reference
Association between small intestine bacterial overgrowth and psychiatric disorders
10.3389/fendo.2024.1438066 · ExternalCitation · doi-reference
Beyond thyroid dysfunction: The systemic impact of iodine excess
10.3389/fendo.2025.1568807 · ExternalCitation · doi-reference
Application progress of artificial intelligence in managing thyroid disease
10.3389/fendo.2025.1578455 · ExternalCitation · doi-reference
How do intestinal probiotics restore the intestinal barrier?
10.3389/fmicb.2022.929346 · ExternalCitation · doi-reference
Aquaporins as targets of dietary bioactive phytocompounds
10.3389/fmolb.2018.00030 · ExternalCitation · doi-reference
Brain functional connectivity in hyperthyroid patients: Systematic review
10.3389/fnins.2024.1383355 · ExternalCitation · doi-reference
The influence of oxidative stress on thyroid diseases
10.3390/antiox10091442 · ExternalCitation · doi-reference
Coenzyme Q10 and endocrine disorders: An overview
10.3390/antiox12020514 · ExternalCitation · doi-reference
Beyond the GFAP-astrocyte protein markers in the brain
10.3390/biom11091361 · ExternalCitation · doi-reference
Oxidative stress, mitochondrial dysfunction, and neuroprotection of polyphenols with respect to resveratrol in parkinson's disease
10.3390/biomedicines9080918 · ExternalCitation · doi-reference
Synthesis and significance of arachidonic acid, a substrate for cyclooxygenases, lipoxygenases, and cytochrome P450 pathways in the tumorigenesis of glioblastoma multiforme, including a pan-cancer comparative analysis
10.3390/cancers15030946 · ExternalCitation · doi-reference
Interaction of mitochondrial calcium and ROS in neurodegeneration
10.3390/cells11040706 · ExternalCitation · doi-reference
The role of glutamate and blood–brain barrier disruption as a mechanistic link between epilepsy and depression
10.3390/cells13141228 · ExternalCitation · doi-reference
Thyroid hormone supplementation restores cognitive deficit, insulin signaling, and neuroinflammation in the hippocampus of a sporadic alzheimer’s-like disease rat model
10.3390/cells13211793 · ExternalCitation · doi-reference
Thyroid hormones and brain development: A focus on the role of mitochondria as regulators of developmental time
10.3390/cells14030150 · ExternalCitation · doi-reference
Pharmacological effects of polyphenol phytochemicals on the intestinal inflammation via targeting TLR4/NF-κB signaling pathway
10.3390/ijms23136939 · ExternalCitation · doi-reference
Postischemic neuroprotection of aminoethoxydiphenyl borate associates shortening of peri-infarct depolarizations
10.3390/ijms23137449 · ExternalCitation · doi-reference
Vulnerability of the hippocampus to insults: Links to blood–brain barrier dysfunction
10.3390/ijms25041991 · ExternalCitation · doi-reference
Antioxidant metabolism pathways in vitamins, polyphenols, and selenium: Parallels and divergences
10.3390/ijms25052600 · ExternalCitation · doi-reference
Breaking the barrier: The role of proinflammatory cytokines in BBB dysfunction
10.3390/ijms26083532 · ExternalCitation · doi-reference
The therapeutic potential of propranolol and other beta-blockers in hyperthyroidism
10.3390/ijms26178322 · ExternalCitation · doi-reference
The association of thyroid disease with risk of dementia and cognitive impairment: A systematic review
10.3390/medicina60121917 · ExternalCitation · doi-reference
Autoimmune thyroid disorders: The mediterranean diet as a protective choice
10.3390/nu15183953 · ExternalCitation · doi-reference
Effects of trace elements on endocrine function and pathogenesis of thyroid diseases—A literature review
10.3390/nu17030398 · ExternalCitation · doi-reference
Attenuation of hypothyroidism-induced cognitive impairment by modulating serotonin mediation
10.3390/vetsci10020122 · ExternalCitation · doi-reference
Relationship between mood disorders and thyroid changes
10.36557/2674-8169.2024v6n2p2241-2256 · ExternalCitation · doi-reference
The potency of ginkgo biloba in treating tinnitus: A review
10.37275/ehi.v3i2.34 · ExternalCitation · doi-reference
How thyroid hormone disorder affect the expression of genes related to neurodegeneration in the hippocampus tissue of rats: An experimental study
10.4103/jcls.jcls_34_24 · ExternalCitation · doi-reference
Melatonin and vitamin C modulate cassava diet-induced alteration in reproductive and thyroid functions
10.4103/njecp.njecp_9_21 · ExternalCitation · doi-reference
Exploring the role of phytoconstituents for endocrine disorder: A review
10.5530/pres.20252070 · ExternalCitation · doi-reference
