Research graph
References from Structural biology approaches in neurodegeneration and aging. Local targets link to admitted publications; unresolved targets remain external evidence.
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Unresolved reference
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External reference
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External reference
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Unresolved reference
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Navigating α-synuclein aggregation inhibition: methods, mechanisms, and molecular targets
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Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease
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Protein misfolding and dysregulated protein homeostasis in autoinflammatory diseases and beyond
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Consequences of variability in α-synuclein fibril structure on strain biology
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Tafamidis for autonomic neuropathy in hereditary transthyretin (ATTR) amyloidosis: a review
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Neurodegenerative disorders of Alzheimer, Parkinsonism, amyotrophic lateral sclerosis and multiple sclerosis: an early diagnostic approach for precision treatment
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Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric diseases
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The role of ubiquitin–proteasome system and mitophagy in the pathogenesis of Parkinson’s disease
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An overview on glycation: molecular mechanisms, impact on proteins, pathogenesis, and inhibition
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Redox events in interleukin-1 signaling
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Protein homeostasis and aging: the importance of exquisite quality control
10.1016/j.arr.2010.02.001 · ExternalCitation · doi-reference
“STRESSED OUT”: the role of FUS and TDP-43 in amyotrophic lateral sclerosis
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β-Sheet interfering molecules acting against β-amyloid aggregation and fibrillogenesis
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The current revolution in cryo-EM
10.1016/j.bpj.2016.02.001 · ExternalCitation · doi-reference
A glimpse of structural biology through X-ray crystallography
10.1016/j.cell.2014.10.051 · ExternalCitation · doi-reference
New insights on the structure of alpha-synuclein fibrils using cryo-electron microscopy
10.1016/j.conb.2020.01.014 · ExternalCitation · doi-reference
Probing protein aggregation through spectroscopic insights and multimodal approaches: a comprehensive review for counteracting neurodegenerative disorders
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Ageing-oxidative stress, PTMs and disease
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Mitochondrial dysfunction and oxidative stress in Alzheimer’s disease, and Parkinson’s disease, Huntington’s disease and Amyotrophic Lateral Sclerosis -An updated review
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Activation of NLRP3-Caspase-1 pathway contributes to age-related impairments in cognitive function and synaptic plasticity
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Targeted protein degradation by PROTACs
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Apolipoprotein E: from lipid transport to neurobiology
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