Research graph
References from Unraveling protein function with structural biology approaches. Local targets link to admitted publications; unresolved targets remain external evidence.
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
10.1038/s41592-023-01807-0 · 2023 · External reference
Combined NMR and molecular dynamics conformational filter identifies unambiguously dynamic ensembles of Dengue protease NS2B/NS3pro
10.1038/s42003-023-05584-6 · 2023 · External reference
Implications of a multiscale structure of the yeast nuclear pore complex
10.1016/j.molcel.2023.08.025 · 2023 · External reference
Analyzing protein structure and function
2002 · External reference
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways
10.1038/s41467-025-57034-y · 2025 · External reference
Structural features of the protein kinase domain and targeted binding by small-molecule inhibitors
10.1016/j.jbc.2022.102247 · 2022 · External reference
Advancing time-resolved structural biology: latest strategies in cryo-EM and X-ray crystallography
10.1038/s41592-025-02659-6 · 2025 · External reference
Before and after AlphaFold2: an overview of protein structure prediction
10.3389/fbinf.2023.1120370 · 2023 · External reference
The fine art of integral membrane protein crystallisation
10.1016/j.ymeth.2018.05.014 · 2018 · External reference
A structural perspective on enzymes and their catalytic mechanisms
10.1016/j.sbi.2025.103040 · 2025 · External reference
Structural biology: a golden era
10.1371/journal.pbio.3002187 · 2023 · External reference
CryoEM-based hybrid modeling approaches for structure determination
10.1016/j.mib.2017.10.002 · 2018 · External reference
Structural characterization of an intrinsically disordered protein complex using integrated small-angle neutron scattering and computing
10.1002/pro.4772 · 2023 · External reference
Antibody structure and function: the basis for engineering therapeutics
10.3390/antib8040055 · 2019 · External reference
Engineering robust cellulases for tailored lignocellulosic degradation cocktails
10.3390/ijms21051589 · 2020 · External reference
Cryo-EM: the resolution revolution and drug discovery
10.1177/2472555220960401 · 2021 · External reference
Insights into protein–ligand interactions: mechanisms, models, and methods
10.3390/ijms17020144 · 2016 · External reference
Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance
10.1021/jm060561m · 2006 · External reference
Structural biology of RNA and protein-RNA complexes after AlphaFold3
10.1002/cbic.202401047 · 2025 · External reference
Role of receptor tyrosine kinases mediated signal transduction pathways in tumor growth and angiogenesis—New insight and futuristic vision
10.1016/j.ijbiomac.2021.03.075 · 2021 · External reference
Accelerators for classical molecular dynamics simulations of biomolecules
10.1021/acs.jctc.1c01214 · 2022 · External reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · 2021 · External reference
Physiology, proteins
2022 · External reference
Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy
10.1113/jp274888 · 2018 · External reference
AlphaFold 2 and NMR spectroscopy: partners to understand protein structure, Dynamics and Function
10.3389/fmolb.2022.906437 · 2022 · External reference
Mathematical models describing oxygen binding by hemoglobin
10.1007/s12551-023-01110-4 · 2023 · External reference
Impact of novel detergents on membrane protein studies
10.1016/j.chempr.2022.02.007 · 2022 · External reference
Integrating genetic structural variations and whole-genome sequencing into clinical neurology
2022 · External reference
Structural dynamics: review of time-resolved cryo-EM
10.1107/s2059798322006155 · 2022 · External reference
Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis
10.1038/s42003-025-08597-5 · 2025 · External reference
Experimental methods to study the structure and dynamics of intrinsically disordered regions in proteins
10.1016/j.crstbi.2024.100138 · 2024 · External reference
Dynamics-based drug discovery by time-resolved cryo-EM
10.1016/j.sbi.2025.103001 · 2025 · External reference
Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis
10.1021/acs.chemrev.8b00532 · 2019 · External reference
Protein structure prediction via deep learning: an in-depth review
10.3389/fphar.2025.1498662 · 2025 · External reference
Hybrid computational methods combining experimental information with molecular dynamics
10.1016/j.sbi.2023.102609 · 2023 · External reference
Applications of NMR and computational methodologies to study protein dynamics
10.1016/j.abb.2017.05.002 · 2017 · External reference
Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy
10.1002/prot.25452 · 2018 · External reference
Unresolved reference
External reference
Biochemistry, tertiary protein structure
2025 · External reference
Biochemistry, secondary protein structure
2025 · External reference
Structural variants in the Epb41l4a locus: TAD disruption and Nrep gene misregulation as hypothetical drivers of neurodevelopmental outcomes
10.1038/s41598-024-52545-y · 2024 · External reference
Biochemistry, primary protein structure
2025 · External reference
Hybrid methods for combined experimental and computational determination of protein structure
10.1063/5.0026025 · 2020 · External reference
Applications of molecular dynamics simulation in protein study
10.3390/membranes12090844 · 2022 · External reference
Utilizing molecular dynamics simulations, machine learning, Cryo-EM, and NMR spectroscopy to predict and validate protein dynamics
10.3390/ijms25179725 · 2024 · External reference
Cell–cell communication: new insights and clinical implications
10.1038/s41392-024-01888-z · 2024 · External reference
Single-molecule dynamic structural biology with vertically arranged DNA on a fluorescence microscope
10.1038/s41592-024-02498-x · 2025 · External reference
Irreversible alterations in the hemoglobin structure affect oxygen binding in human packed red blood cells
10.1016/j.bbamcr.2020.118803 · 2020 · External reference
α-Synuclein aggregation is triggered by oligomeric amyloid-β 42 via heterogeneous primary nucleation
10.1021/jacs.3c03212 · 2023 · External reference
Classification of intrinsically disordered regions and proteins
10.1021/cr400525m · 2014 · External reference
AlphaFold protein structure database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
10.1093/nar/gkab1061 · 2022 · External reference
Design, synthesis and biological evaluation of potent epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors against resistance mutation for lung cancer treatment
10.1016/j.bioorg.2023.107004 · 2024 · External reference
Integrative structure modeling with the integrative modeling platform
10.1002/pro.3311 · 2018 · External reference
High-throughput crystallization pipeline at the crystallography core facility of the institut pasteur
10.3390/molecules24244451 · 2019 · External reference
Conformational basis of g protein-coupled receptor signaling versatility
10.1016/j.tcb.2020.06.002 · 2020 · External reference
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography
10.1038/s41557-023-01329-4 · 2023 · External reference
Recent technical advances in sample preparation for single-particle Cryo-EM
10.3389/fmolb.2022.892459 · 2022 · External reference
AlphaFold2 and its applications in the fields of biology and medicine
10.1038/s41392-023-01381-z · 2023 · External reference
TROSY-based NMR experiments for NMR studies of large biomolecules
10.1016/j.pnmrs.2007.10.001 · 2008 · External reference
Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials
10.1186/s13045-022-01314-3 · 2022 · External reference
Advances in integrative structural biology: towards understanding protein complexes in their cellular context
10.1016/j.csbj.2020.11.052 · 2021 · External reference
Structural biology of RNA and protein-RNA complexes after AlphaFold3
10.1002/cbic.202401047 · ExternalCitation · doi-reference
Integrative structure modeling with the integrative modeling platform
10.1002/pro.3311 · ExternalCitation · doi-reference
Structural characterization of an intrinsically disordered protein complex using integrated small-angle neutron scattering and computing
10.1002/pro.4772 · ExternalCitation · doi-reference
Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy
10.1002/prot.25452 · ExternalCitation · doi-reference
Mathematical models describing oxygen binding by hemoglobin
10.1007/s12551-023-01110-4 · ExternalCitation · doi-reference
Applications of NMR and computational methodologies to study protein dynamics
10.1016/j.abb.2017.05.002 · ExternalCitation · doi-reference
Irreversible alterations in the hemoglobin structure affect oxygen binding in human packed red blood cells
10.1016/j.bbamcr.2020.118803 · ExternalCitation · doi-reference
Design, synthesis and biological evaluation of potent epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors against resistance mutation for lung cancer treatment
10.1016/j.bioorg.2023.107004 · ExternalCitation · doi-reference
Impact of novel detergents on membrane protein studies
10.1016/j.chempr.2022.02.007 · ExternalCitation · doi-reference
Experimental methods to study the structure and dynamics of intrinsically disordered regions in proteins
10.1016/j.crstbi.2024.100138 · ExternalCitation · doi-reference
Advances in integrative structural biology: towards understanding protein complexes in their cellular context
10.1016/j.csbj.2020.11.052 · ExternalCitation · doi-reference
Role of receptor tyrosine kinases mediated signal transduction pathways in tumor growth and angiogenesis—New insight and futuristic vision
10.1016/j.ijbiomac.2021.03.075 · ExternalCitation · doi-reference
Structural features of the protein kinase domain and targeted binding by small-molecule inhibitors
10.1016/j.jbc.2022.102247 · ExternalCitation · doi-reference
CryoEM-based hybrid modeling approaches for structure determination
10.1016/j.mib.2017.10.002 · ExternalCitation · doi-reference
Implications of a multiscale structure of the yeast nuclear pore complex
10.1016/j.molcel.2023.08.025 · ExternalCitation · doi-reference
TROSY-based NMR experiments for NMR studies of large biomolecules
10.1016/j.pnmrs.2007.10.001 · ExternalCitation · doi-reference
Hybrid computational methods combining experimental information with molecular dynamics
10.1016/j.sbi.2023.102609 · ExternalCitation · doi-reference
Dynamics-based drug discovery by time-resolved cryo-EM
10.1016/j.sbi.2025.103001 · ExternalCitation · doi-reference
A structural perspective on enzymes and their catalytic mechanisms
10.1016/j.sbi.2025.103040 · ExternalCitation · doi-reference
Conformational basis of g protein-coupled receptor signaling versatility
10.1016/j.tcb.2020.06.002 · ExternalCitation · doi-reference
The fine art of integral membrane protein crystallisation
10.1016/j.ymeth.2018.05.014 · ExternalCitation · doi-reference
Folding and misfolding of human membrane proteins in health and disease: from single molecules to cellular proteostasis
10.1021/acs.chemrev.8b00532 · ExternalCitation · doi-reference
Accelerators for classical molecular dynamics simulations of biomolecules
10.1021/acs.jctc.1c01214 · ExternalCitation · doi-reference
Classification of intrinsically disordered regions and proteins
10.1021/cr400525m · ExternalCitation · doi-reference
α-Synuclein aggregation is triggered by oligomeric amyloid-β 42 via heterogeneous primary nucleation
10.1021/jacs.3c03212 · ExternalCitation · doi-reference
Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance
10.1021/jm060561m · ExternalCitation · doi-reference
AlphaFold2 and its applications in the fields of biology and medicine
10.1038/s41392-023-01381-z · ExternalCitation · doi-reference
Cell–cell communication: new insights and clinical implications
10.1038/s41392-024-01888-z · ExternalCitation · doi-reference
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways
10.1038/s41467-025-57034-y · ExternalCitation · doi-reference
Mapping protein dynamics at high spatial resolution with temperature-jump X-ray crystallography
10.1038/s41557-023-01329-4 · ExternalCitation · doi-reference
Highly accurate protein structure prediction with AlphaFold
10.1038/s41586-021-03819-2 · ExternalCitation · doi-reference
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
10.1038/s41592-023-01807-0 · ExternalCitation · doi-reference
Single-molecule dynamic structural biology with vertically arranged DNA on a fluorescence microscope
10.1038/s41592-024-02498-x · ExternalCitation · doi-reference
Advancing time-resolved structural biology: latest strategies in cryo-EM and X-ray crystallography
10.1038/s41592-025-02659-6 · ExternalCitation · doi-reference
Structural variants in the Epb41l4a locus: TAD disruption and Nrep gene misregulation as hypothetical drivers of neurodevelopmental outcomes
10.1038/s41598-024-52545-y · ExternalCitation · doi-reference
Combined NMR and molecular dynamics conformational filter identifies unambiguously dynamic ensembles of Dengue protease NS2B/NS3pro
10.1038/s42003-023-05584-6 · ExternalCitation · doi-reference
Combined thermodynamic and time-resolved structural analysis of interactions between AP2 and biomimetic plasma membranes provides insights into clathrin-mediated endocytosis
10.1038/s42003-025-08597-5 · ExternalCitation · doi-reference
Hybrid methods for combined experimental and computational determination of protein structure
10.1063/5.0026025 · ExternalCitation · doi-reference
AlphaFold protein structure database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
10.1093/nar/gkab1061 · ExternalCitation · doi-reference
Structural dynamics: review of time-resolved cryo-EM
10.1107/s2059798322006155 · ExternalCitation · doi-reference
Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy
10.1113/jp274888 · ExternalCitation · doi-reference
Cryo-EM: the resolution revolution and drug discovery
10.1177/2472555220960401 · ExternalCitation · doi-reference
Targeting p53–MDM2 interaction by small-molecule inhibitors: learning from MDM2 inhibitors in clinical trials
10.1186/s13045-022-01314-3 · ExternalCitation · doi-reference
Structural biology: a golden era
10.1371/journal.pbio.3002187 · ExternalCitation · doi-reference
Before and after AlphaFold2: an overview of protein structure prediction
10.3389/fbinf.2023.1120370 · ExternalCitation · doi-reference
Recent technical advances in sample preparation for single-particle Cryo-EM
10.3389/fmolb.2022.892459 · ExternalCitation · doi-reference
AlphaFold 2 and NMR spectroscopy: partners to understand protein structure, Dynamics and Function
10.3389/fmolb.2022.906437 · ExternalCitation · doi-reference
Protein structure prediction via deep learning: an in-depth review
10.3389/fphar.2025.1498662 · ExternalCitation · doi-reference
Antibody structure and function: the basis for engineering therapeutics
10.3390/antib8040055 · ExternalCitation · doi-reference
Insights into protein–ligand interactions: mechanisms, models, and methods
10.3390/ijms17020144 · ExternalCitation · doi-reference
Engineering robust cellulases for tailored lignocellulosic degradation cocktails
10.3390/ijms21051589 · ExternalCitation · doi-reference
Utilizing molecular dynamics simulations, machine learning, Cryo-EM, and NMR spectroscopy to predict and validate protein dynamics
10.3390/ijms25179725 · ExternalCitation · doi-reference
Applications of molecular dynamics simulation in protein study
10.3390/membranes12090844 · ExternalCitation · doi-reference
High-throughput crystallization pipeline at the crystallography core facility of the institut pasteur
10.3390/molecules24244451 · ExternalCitation · doi-reference
