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References from Structural and systems biology in cancer therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.3390/ijms22062822
10.3390/ijms22062822 · External reference
Allosteric modulators: an emerging concept in drug discovery
10.1021/ml5005365 · 2015 · External reference
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Molecular dynamic simulations and molecular docking as a potential way for designed new inhibitor drug without resistance
2022 · External reference
Biomarkers as biomedical bioindicators: approaches and techniques for the detection, analysis, and validation of novel biomarkers of diseases
10.3390/pharmaceutics15061630 · 2023 · External reference
The evolution of cancer immunotherapy: a comprehensive review of its history and current perspectives
10.14216/kjco.24009 · 2024 · External reference
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Network medicine: a network-based approach to human disease
10.1038/nrg2918 · 2011 · External reference
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XThe dynamics of signaling as a pharmacological target
10.1016/j.cell.2013.09.018 · 2013 · External reference
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10.1002/1878-0261.13277
10.1002/1878-0261.13277 · External reference
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The difficulties in cancer treatment
2012 · External reference
Applications of multi-omics analysis in human diseases
10.1002/mco2.315 · 2023 · External reference
Using artificial intelligence to develop clinical decision support systems—the evolving road of personalized oncologic therapy
10.3390/diagnostics15182391 · 2025 · External reference
Antibody structure and function: The basis for engineering therapeutics
10.3390/antib8040055 · 2019 · External reference
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10.3390/life15081248
10.3390/life15081248 · External reference
Molecular basis of BRAF inhibitor resistance in melanoma: a systematic review
10.3390/ph18081235 · 2025 · External reference
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Integration of multi-omics approaches in exploring intra-tumoral heterogeneity
10.1186/s12935-025-03944-2 · 2025 · External reference
Advances in tumor microenvironment: applications and challenges of 3D bioprinting
10.1016/j.bbrc.2024.150339 · 2024 · External reference
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Next-generation sequencing in cancer diagnosis and treatment: clinical applications and future directions
10.1007/s12672-025-01816-9 · 2025 · External reference
Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problem
10.1016/j.drudis.2012.06.018 · 2012 · External reference
The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
10.1016/j.molonc.2011.07.001 · 2011 · External reference
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Antibody–drug conjugates in cancer therapy: mechanisms and clinical studies
10.1002/mco2.671 · 2024 · External reference
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10.3390/ijms17020144
10.3390/ijms17020144 · External reference
Accurate prediction of synergistic drug combination using a multi-source information fusion framework
10.1186/s12915-025-02302-y · 2025 · External reference
The rising burden of cancer in the developing world
10.1093/annonc/mdl983 · 2006 · External reference
Gene regulatory network reconstruction: harnessing the power of single-cell multi-omic data
10.1038/s41540-023-00312-6 · 2023 · External reference
An introduction to NMR-based approaches for measuring protein dynamics
10.1016/j.bbapap.2010.10.012 · 2011 · External reference
From “omics” to complex disease: a systems biology approach to gene-environment interactions in cancer
10.1186/1475-2867-10-11 · 2010 · External reference
Complexity in cancer biology: is systems biology the answer?
10.1002/cam4.62 · 2013 · External reference
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Cancer systems biology: a network modeling perspective
10.1093/carcin/bgp261 · 2010 · External reference
A systems biology view of cancer
10.1016/j.bbcan.2009.06.001 · 2009 · External reference
Trends in the cost of cancer care: Beyond drugs
10.1200/jco.19.01963 · 2020 · External reference
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Application of fragment-based drug discovery to versatile targets
10.3389/fmolb.2020.00180 · 2020 · External reference
Structure-based virtual screening for drug discovery: principles, applications and recent advances
10.2174/1568026614666140929124445 · 2014 · External reference
The role of multi-omics in biomarker discovery, diagnosis, prognosis, and therapeutic monitoring of tissue repair and regeneration processes
10.1016/j.jot.2025.07.006 · 2025 · External reference
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Managing Resistance to EFGR- and ALK-targeted therapies
10.1200/edbk_176251 · 2017 · External reference
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10.3390/genes14020429
10.3390/genes14020429 · External reference
10.3390/membranes12020227
10.3390/membranes12020227 · External reference
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Emerging landscape of molecular interaction networks: opportunities, challenges and prospects
10.1007/s12038-022-00253-y · 2022 · External reference
10.1002/pro.3774
10.1002/pro.3774 · External reference
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment
10.1016/j.cell.2024.02.041 · 2024 · External reference
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Editorial: structural studies of protein complexes in signaling pathways
10.3389/fmolb.2021.641932 · 2021 · External reference
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Mathematical oncology: how modeling is transforming clinical decision-making
10.1158/0008-5472.can-25-0750 · 2025 · External reference
Population-based screening for cancer: hope and hype
10.1038/nrclinonc.2016.50 · 2016 · External reference
RAS proteins and their regulators in human disease
10.1016/j.cell.2017.06.009 · 2017 · External reference
x Ray crystallography
10.1136/mp.53.1.8 · 2000 · External reference
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
10.1016/j.molcel.2016.06.022 · 2016 · External reference
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Multi-omics data integration, interpretation, and its application
10.1177/1177932219899051 · 2020 · External reference
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TCR recognition of peptide–MHC-I: rule makers and breakers
10.3390/ijms22010068 · 2021 · External reference
Extracellular vesicles as a promising biomarker resource in liquid biopsy for cancer
2021 · External reference
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10.1371/journal.pntd.0012985
10.1371/journal.pntd.0012985 · External reference
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RNA-Seq: a revolutionary tool for transcriptomics
10.1038/nrg2484 · 2009 · External reference
Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures
10.1111/j.1742-4658.2007.06178.x · 2008 · External reference
AlphaFold2 and its applications in the fields of biology and medicine
10.1038/s41392-023-01381-z · 2023 · External reference
Proteomics appending a complementary dimension to precision oncotherapy
10.1016/j.csbj.2024.04.044 · 2024 · External reference
10.1002/1878-0261.13277
10.1002/1878-0261.13277 · ExternalCitation · doi-reference
Complexity in cancer biology: is systems biology the answer?
10.1002/cam4.62 · ExternalCitation · doi-reference
Applications of multi-omics analysis in human diseases
10.1002/mco2.315 · ExternalCitation · doi-reference
Antibody–drug conjugates in cancer therapy: mechanisms and clinical studies
10.1002/mco2.671 · ExternalCitation · doi-reference
10.1002/pro.3774
10.1002/pro.3774 · ExternalCitation · doi-reference
Emerging landscape of molecular interaction networks: opportunities, challenges and prospects
10.1007/s12038-022-00253-y · ExternalCitation · doi-reference
Next-generation sequencing in cancer diagnosis and treatment: clinical applications and future directions
10.1007/s12672-025-01816-9 · ExternalCitation · doi-reference
An introduction to NMR-based approaches for measuring protein dynamics
10.1016/j.bbapap.2010.10.012 · ExternalCitation · doi-reference
A systems biology view of cancer
10.1016/j.bbcan.2009.06.001 · ExternalCitation · doi-reference
Advances in tumor microenvironment: applications and challenges of 3D bioprinting
10.1016/j.bbrc.2024.150339 · ExternalCitation · doi-reference
XThe dynamics of signaling as a pharmacological target
10.1016/j.cell.2013.09.018 · ExternalCitation · doi-reference
RAS proteins and their regulators in human disease
10.1016/j.cell.2017.06.009 · ExternalCitation · doi-reference
Cancer biomarkers: Emerging trends and clinical implications for personalized treatment
10.1016/j.cell.2024.02.041 · ExternalCitation · doi-reference
Proteomics appending a complementary dimension to precision oncotherapy
10.1016/j.csbj.2024.04.044 · ExternalCitation · doi-reference
Structure-based methods for predicting target mutation-induced drug resistance and rational drug design to overcome the problem
10.1016/j.drudis.2012.06.018 · ExternalCitation · doi-reference
The role of multi-omics in biomarker discovery, diagnosis, prognosis, and therapeutic monitoring of tissue repair and regeneration processes
10.1016/j.jot.2025.07.006 · ExternalCitation · doi-reference
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
10.1016/j.molcel.2016.06.022 · ExternalCitation · doi-reference
The underlying mechanism for the PARP and BRCA synthetic lethality: Clearing up the misunderstandings
10.1016/j.molonc.2011.07.001 · ExternalCitation · doi-reference
Allosteric modulators: an emerging concept in drug discovery
10.1021/ml5005365 · ExternalCitation · doi-reference
Population-based screening for cancer: hope and hype
10.1038/nrclinonc.2016.50 · ExternalCitation · doi-reference
RNA-Seq: a revolutionary tool for transcriptomics
10.1038/nrg2484 · ExternalCitation · doi-reference
Network medicine: a network-based approach to human disease
10.1038/nrg2918 · ExternalCitation · doi-reference
AlphaFold2 and its applications in the fields of biology and medicine
10.1038/s41392-023-01381-z · ExternalCitation · doi-reference
Gene regulatory network reconstruction: harnessing the power of single-cell multi-omic data
10.1038/s41540-023-00312-6 · ExternalCitation · doi-reference
The rising burden of cancer in the developing world
10.1093/annonc/mdl983 · ExternalCitation · doi-reference
Cancer systems biology: a network modeling perspective
10.1093/carcin/bgp261 · ExternalCitation · doi-reference
Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures
10.1111/j.1742-4658.2007.06178.x · ExternalCitation · doi-reference
x Ray crystallography
10.1136/mp.53.1.8 · ExternalCitation · doi-reference
Mathematical oncology: how modeling is transforming clinical decision-making
10.1158/0008-5472.can-25-0750 · ExternalCitation · doi-reference
Multi-omics data integration, interpretation, and its application
10.1177/1177932219899051 · ExternalCitation · doi-reference
From “omics” to complex disease: a systems biology approach to gene-environment interactions in cancer
10.1186/1475-2867-10-11 · ExternalCitation · doi-reference
Accurate prediction of synergistic drug combination using a multi-source information fusion framework
10.1186/s12915-025-02302-y · ExternalCitation · doi-reference
Integration of multi-omics approaches in exploring intra-tumoral heterogeneity
10.1186/s12935-025-03944-2 · ExternalCitation · doi-reference
Managing Resistance to EFGR- and ALK-targeted therapies
10.1200/edbk_176251 · ExternalCitation · doi-reference
Trends in the cost of cancer care: Beyond drugs
10.1200/jco.19.01963 · ExternalCitation · doi-reference
10.1371/journal.pntd.0012985
10.1371/journal.pntd.0012985 · ExternalCitation · doi-reference
The evolution of cancer immunotherapy: a comprehensive review of its history and current perspectives
10.14216/kjco.24009 · ExternalCitation · doi-reference
Structure-based virtual screening for drug discovery: principles, applications and recent advances
10.2174/1568026614666140929124445 · ExternalCitation · doi-reference
Application of fragment-based drug discovery to versatile targets
10.3389/fmolb.2020.00180 · ExternalCitation · doi-reference
Editorial: structural studies of protein complexes in signaling pathways
10.3389/fmolb.2021.641932 · ExternalCitation · doi-reference
Antibody structure and function: The basis for engineering therapeutics
10.3390/antib8040055 · ExternalCitation · doi-reference
Using artificial intelligence to develop clinical decision support systems—the evolving road of personalized oncologic therapy
10.3390/diagnostics15182391 · ExternalCitation · doi-reference
10.3390/genes14020429
10.3390/genes14020429 · ExternalCitation · doi-reference
10.3390/ijms17020144
10.3390/ijms17020144 · ExternalCitation · doi-reference
TCR recognition of peptide–MHC-I: rule makers and breakers
10.3390/ijms22010068 · ExternalCitation · doi-reference
10.3390/ijms22062822
10.3390/ijms22062822 · ExternalCitation · doi-reference
10.3390/life15081248
10.3390/life15081248 · ExternalCitation · doi-reference
10.3390/membranes12020227
10.3390/membranes12020227 · ExternalCitation · doi-reference
Molecular basis of BRAF inhibitor resistance in melanoma: a systematic review
10.3390/ph18081235 · ExternalCitation · doi-reference
Biomarkers as biomedical bioindicators: approaches and techniques for the detection, analysis, and validation of novel biomarkers of diseases
10.3390/pharmaceutics15061630 · ExternalCitation · doi-reference
