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References from CD74 accumulation in macrophages suppresses efferocytosis and exacerbates atherosclerosis by interfering with myosin II function. Local targets link to admitted publications; unresolved targets remain external evidence.
Atherosclerosis antigens as targets for immunotherapy
10.1038/s44161-023-00376-x · 2023 · External reference
Research Progress on the Relationship between Atherosclerosis and Inflammation
10.3390/biom8030080 · 2018 · External reference
Inflammation, infection and atherosclerosis
10.1016/j.tcm.2019.01.004 · 2019 · External reference
Microbiota-Mediated Immune Regulation in Atherosclerosis
10.3390/molecules26010179 · 2021 · External reference
Macrophages in Atherosclerosis Regression
10.1161/atvbaha.119.312802 · 2020 · External reference
Monocyte Recruitment, Specification, and Function in Atherosclerosis
10.3390/cells10010015 · 2020 · External reference
ANGPTL8 deletion attenuates abdominal aortic aneurysm formation in ApoE-/- mice
10.1042/cs20230031 · 2023 · External reference
Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages
10.1016/j.cell.2017.08.041 · 2017 · External reference
HIF-1α and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages
10.1161/atvbaha.115.305551 · 2015 · External reference
Regulation of Macrophage Apoptosis and Atherosclerosis by Lipid-Induced PKCδ Isoform Activation
10.1161/circresaha.117.311606 · 2017 · External reference
Krüppel-like factor 14 deletion in myeloid cells accelerates atherosclerotic lesion development
10.1093/cvr/cvab027 · 2022 · External reference
Targeting Efferocytosis in Inflammaging
10.1146/annurev-pharmtox-032723-110507 · 2024 · External reference
The Role of Efferocytosis in Atherosclerosis
10.1161/circulationaha.116.025684 · 2017 · External reference
Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities
2019 · External reference
Inflammation and its resolution as determinants of acute coronary syndromes
10.1161/circresaha.114.302699 · 2014 · External reference
Efferocytosis and Atherosclerosis: Regulation of Phagocyte Function by MicroRNAs
10.1016/j.tem.2019.07.006 · 2019 · External reference
Inflammatory Factors Driving Atherosclerotic Plaque Progression New Insights
10.2478/jtim-2022-0012 · 2022 · External reference
The role of CD74 in cardiovascular disease
10.3389/fcvm.2022.1077332 · 2022 · External reference
Increased Expression of CD74 in Atherosclerosis Associated with Inflammatory Responses of Endothelial Cells and Macrophages
10.1007/s10528-023-10421-w · 2024 · External reference
CD74: a prospective marker for reactive microglia?
10.4103/1673-5374.371350 · 2023 · External reference
CD74 in Apoptotic Macrophages Is Associated with Inflammation, Plaque Progression and Clinical Manifestations in Human Atherosclerotic Lesions
10.3390/metabo12010054 · 2022 · External reference
Cathepsin S are involved in human carotid atherosclerotic disease progression, mainly by mediating phagosomes: bioinformatics and in vivo and vitro experiments
2022 · External reference
Rai14 is a novel interactor of Invariant chain that regulates macropinocytosis
10.3389/fimmu.2023.1182180 · 2023 · External reference
Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain
10.1126/science.1159894 · 2008 · External reference
[The role of macrophage efferocytosis in non-infectious inflammatory diseases]
2026 · External reference
Impaired Macrophage Efferocytosis: Shared Mechanisms and Therapeutic Implications in Immune-Mediated Inflammatory Diseases
10.2147/jir.s582297 · 2026 · External reference
CD74 is a functional MIF receptor on activated CD4(+) T cells
10.1007/s00018-024-05338-5 · 2024 · External reference
Role of MIF Cytokine/CD74 Receptor Pathway in Protecting Against Injury and Promoting Repair
10.3389/fimmu.2020.01273 · 2020 · External reference
CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells
10.18632/oncotarget.11945 · 2016 · External reference
B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A
10.1084/jem.20121076 · 2013 · External reference
CCL2 is transcriptionally controlled by the lysosomal protease cathepsin S in a CD74-dependent manner
10.18632/oncotarget.5065 · 2015 · External reference
Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression
10.1016/j.jaut.2022.102810 · 2022 · External reference
Processing of CD74 by the Intramembrane Protease SPPL2a Is Critical for B Cell Receptor Signaling in Transitional B Cells
10.4049/jimmunol.1403171 · 2015 · External reference
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
10.1084/jem.20121069 · 2013 · External reference
A contractile activity that closes phagosomes in macrophages
10.1242/jcs.112.3.307 · 1999 · External reference
Phagocytosis: Our Current Understanding of a Universal Biological Process
10.3389/fimmu.2020.01066 · 2020 · External reference
Phagocytic 'teeth' and myosin-II 'jaw' power target constriction during phagocytosis
10.7554/elife.68627 · 2021 · External reference
Building the phagocytic cup on an actin scaffold
10.1016/j.ceb.2022.102112 · 2022 · External reference
