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References from Gas phase charge reduction for improved protein characterization by mass spectrometry. Local targets link to admitted publications; unresolved targets remain external evidence.
Extracting charge and mass information from highly congested mass spectra using fourier-domain harmonics
10.1007/s13361-018-2018-7 · 2018 · External reference
Fourier analysis method for analyzing highly congested mass spectra of ion populations with repeated subunits
10.1021/acs.analchem.6b01088 · 2016 · External reference
From protein complexes to subunit backbone fragments: a multi-stage approach to native mass spectrometry
10.1021/ac4029328 · 2013 · External reference
Native Top-down analysis of membrane protein complexes directly from in vitro and native membranes
10.1016/j.mcpro.2025.100993 · 2025 · External reference
Ribosome heterogeneity revealed by Complex-Up native mass spectrometry and top-down proteomics
10.1021/jacs.5c21227 · 2026 · External reference
Native mass spectrometry: recent progress and remaining challenges
10.1146/annurev-biophys-092721-085421 · 2022 · External reference
Mechanistic aspects of electrospray ionization
10.1016/s0021-9673(97)01110-2 · 1998 · External reference
Electrospray ionization for mass spectrometry of large biomolecules
10.1126/science.2675315 · 1989 · External reference
Unresolved reference
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Features of the ESI mechanism that affect the observation of multiply charged noncovalent protein complexes and the determination of the association constant by the titration method
10.1016/j.jasms.2004.05.005 · 2004 · External reference
Electrospray: from ions in solution to ions in the gas phase, what we know now
10.1002/mas.20247 · 2009 · External reference
Estimates of protein surface areas in solution by electrospray ionization mass spectrometry
10.1021/ac050511+ · 2005 · External reference
Charge-surface correlation in electrospray ionization of folded and unfolded proteins
10.1021/ac201740z · 2011 · External reference
Analysis of native-like proteins and protein complexes using cation to anion proton transfer reactions (CAPTR)
10.1007/s13361-015-1245-4 · 2015 · External reference
Electrospray ionization mass spectrometry of highly heterogeneous protein systems: protein ion charge state assignment via incomplete charge reduction
10.1021/ac101848z · 2010 · External reference
Coupling charge reduction mass spectrometry to liquid chromatography for complex mixture analysis
10.1021/acs.analchem.6b00485 · 2016 · External reference
Electron transfer dissociation of oligonucleotide cations
10.1016/j.ijms.2009.02.012 · 2009 · External reference
Recent developments in the ion/ion chemistry of high‐mass multiply charged ions
10.1002/mas.20048 · 2005 · External reference
Unresolved reference
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A new approach for the study of gas-phase ion-ion reactions using electrospray ionization
10.1016/1044-0305(92)87082-a · 1992 · External reference
Implementation of ion/ion reactions in a quadrupole/time-Of-flight tandem mass spectrometer
10.1021/ac0606296 · 2006 · External reference
Ion-ion proton transfer and parallel ion parking for the analysis of mixtures of intact proteins on a modified orbitrap mass analyzer
10.1007/s13361-019-02290-8 · 2019 · External reference
Mutual storage mode ion/ion reactions in a hybrid linear ion trap
10.1016/j.jasms.2004.09.017 · 2005 · External reference
Fragmentation of oligoribonucleotides from gas-phase ion-electron reactions
10.1016/j.jasms.2006.05.006 · 2006 · External reference
Nonergodic and conformational control of the electron capture dissociation of protein cations
10.1073/pnas.0406095101 · 2004 · External reference
The role of electron transfer dissociation in modern proteomics
10.1021/acs.analchem.7b04810 · 2018 · External reference
Native electrospray and electron-capture dissociation FTICR mass spectrometry for top-down studies of protein assemblies
10.1021/ac200695d · 2011 · External reference
Phosphopeptide/phosphoprotein mapping by electron capture dissociation mass spectrometry
10.1021/ac000703z · 2001 · External reference
Moment theory of ion-neutral reactions in traps and similar devices
10.1021/jp066096m · 2007 · External reference
Ion/neutral, ion/electron, ion/photon, and ion/ion interactions in tandem mass spectrometry: do we need them all? Are they enough?
10.1007/s13361-010-0004-9 · 2011 · External reference
Boundaries of mass resolution in native mass spectrometry
10.1007/s13361-014-0874-3 · 2014 · External reference
Ion/ion reactions: new chemistry for analytical MS
10.1021/ac9014935 · 2009 · External reference
Structures of fluoranthene reagent anions used in electron transfer dissociation and proton transfer reaction tandem mass spectrometry
10.1021/acs.analchem.6b01483 · 2016 · External reference
Ion activation methods for peptides and proteins
10.1021/acs.analchem.9b04859 · 2020 · External reference
Recent developments in gas-phase ion/ion reactions for analytical mass spectrometry
10.1021/acs.analchem.9b05014 · 2020 · External reference
Ion/ion reactions in the gas phase: proton transfer reactions involving multiply-charged proteins
10.1021/ja9611755 · 1996 · External reference
Optimization of electron transfer dissociation via informed selection of reagents and operating parameters
10.1021/ac202807h · 2012 · External reference
Ion–ion charge reduction addresses multiple challenges common to denaturing intact mass analysis
10.1021/acs.analchem.1c04973 · 2022 · External reference
Proton transfer reagent cations for ion–ion charge state manipulation of high mass negatively-charged analytes in an electrodynamic ion trap
2026 · External reference
Ion/ion proton transfer reactions for protein mixture analysis
10.1021/ac9605657 · 1996 · External reference
Reactions of poly(ethylene glycol) cations with iodide and perfluorocarbon anions
10.1016/s1044-0305(98)00066-x · 1998 · External reference
Ion parking in native mass spectrometry
10.1039/d4an00242c · 2024 · External reference
Ion parking during ion/ion reactions in electrodynamic ion traps
10.1021/ac0109671 · 2002 · External reference
Parallel ion parking of protein mixtures
10.1021/ac0515778 · 2006 · External reference
Proton transfer charge reduction enables high-throughput top-down analysis of large proteoforms
10.1021/acs.analchem.9b03925 · 2019 · External reference
Effects of charge on protein ion structure: lessons from cation-to-anion, proton-transfer reactions
10.1002/mas.21847 · 2024 · External reference
Native-like and denatured cytochrome c ions yield cation-to-anion proton transfer reaction products with similar collision cross-sections
10.1007/s13361-017-1620-4 · 2017 · External reference
Charge reduction electrospray mass spectrometry
10.1021/ac990878c · 2000 · External reference
Coupling electrospray Corona discharge, charge reduction and ion mobility mass spectrometry: from peptides to large macromolecular protein complexes
10.1007/s12127-013-0120-x · 2013 · External reference
Corona discharge in charge reduction electrospray mass spectrometry
10.1021/ac000559h · 2000 · External reference
A cylindrical capacitor ionization source: droplet generation and controlled charge reduction for mass spectrometry
10.1002/rcm.245 · 2001 · External reference
From congestion to clarity: on the complementarity of resolving power and spectral simplification for intact protein characterization
10.1021/jasms.6c00016 · 2026 · External reference
Electron transfer dissociation of milk oligosaccharides
10.1007/s13361-011-0117-9 · 2011 · External reference
Improving accuracy in mass spectrometry-based mass determination of intact heterogeneous protein utilizing the universal benefits of charge reduction and alternative gas-phase reactions
10.1021/acs.analchem.2c02586 · 2022 · External reference
Electron transfer with no dissociation ion mobility–mass spectrometry (ETnoD IM-MS). The effect of charge reduction on protein conformation
10.1016/j.ijms.2016.08.006 · 2017 · External reference
Direct identification of intact proteins using a low-resolution mass spectrometer with CIDn/ETnoD
10.1021/jasms.4c00108 · 2024 · External reference
Extensive charge reduction and dissociation of intact protein complexes following electron transfer on a quadrupole-ion mobility-time-of-flight MS
10.1007/s13361-015-1124-z · 2015 · External reference
Dipolar DC induced collisional activation of non‐dissociated electron‐transfer products
10.1002/jms.4352 · 2019 · External reference
Probing asymmetric charge partitioning of protein oligomers during tandem mass spectrometry
10.1016/j.ijms.2015.08.021 · 2015 · External reference
Multiply charged cation attachment to facilitate mass measurement in negative-mode native mass spectrometry
10.1021/acs.analchem.1c04875 · 2022 · External reference
Digital ion trap isolation and mass analysis of macromolecular analytes with multiply charged ion attachment
10.1021/jasms.4c00292 · 2024 · External reference
Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation
10.1021/acscentsci.4c00461 · 2024 · External reference
Electron capture-induced charge reduction benefits the recording of ultralong transients in orbitrap-based individual-ion mass spectrometry
10.1021/acs.analchem.5c01000 · 2025 · External reference
To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes
10.1021/acscentsci.4c00462 · 2024 · External reference
Streamlining the analysis of proteins from snake venom
10.1021/acs.jproteome.4c00013 · 2024 · External reference
Exposing the molecular heterogeneity of glycosylated biotherapeutics
10.1038/s41467-024-47693-8 · 2024 · External reference
Analytical applications of ion-molecule reactions
10.1002/(sici)1098-2787(1997)16:2<91::aid-mas3>3.0.co;2-4 · 1997 · External reference
Investigation of the gas-phase structure of electrosprayed proteins using ion-molecule reactions
10.1016/1044-0305(94)85011-9 · 1994 · External reference
Reactions of dimethylamine with multiply charged ions of cytochrome c
10.1021/ja00170a057 · 1990 · External reference
Protein structural effects in gas phase ion/molecule reactions with diethylamine
10.1002/rcm.1290060302 · 1992 · External reference
Probing qualitative conformation differences of multiply protonated gas-phase proteins via hydrogen/deuterium isotopic exchange with water-d2
10.1021/ja00040a084 · 1992 · External reference
Protons are fast and smart; proteins are slow and dumb: on the relationship of electrospray ionization charge states and conformations
10.1021/jasms.1c00100 · 2021 · External reference
Enhancing top-down analysis of proteins by combining ultraviolet photodissociation (UVPD), proton-transfer charge reduction (PTCR), and gas-phase fractionation to alleviate the impact of nondissociated precursor ions
10.1021/jasms.3c00351 · 2024 · External reference
Ion/ion proton-transfer kinetics: implications for analysis of ions derived from electrospray of protein mixtures
10.1021/ac9710137 · 1998 · External reference
Simplification of product ion spectra derived from multiply charged parent ions via ion/ion chemistry
10.1021/ac9802832 · 1998 · External reference
Improved characterization of trastuzumab deruxtecan with PTCR and internal fragments implemented in middle-down MS workflows
10.1007/s00216-023-05059-x · 2024 · External reference
Advanced strategies for proton-transfer reactions coupled with parallel ion parking on a 21 T FT-ICR MS for intact protein analysis
10.1021/acs.analchem.1c00847 · 2021 · External reference
Integration of ultraviolet photodissociation with proton transfer reactions and ion parking for analysis of intact proteins
10.1021/acs.analchem.5b03911 · 2016 · External reference
Analysis of proteins and peptides on a chromatographic timescale by electron‐transfer dissociation MS
10.1111/j.1742-4658.2007.06148.x · 2007 · External reference
Ion activation methods for peptides and proteins
10.1021/acs.analchem.5b04563 · 2016 · External reference
193 nm ultraviolet photodissociation mass spectrometry of tetrameric protein complexes provides insight into Quaternary and secondary protein topology
10.1021/jacs.6b03905 · 2016 · External reference
Top-down analysis of supercharged proteins using Collision-, Electron-, and photon-based activation methods
10.1021/jasms.3c00138 · 2023 · External reference
Enhanced sequence coverage of large proteins by combining ultraviolet photodissociation with proton transfer reactions
10.1021/acs.analchem.9b04026 · 2020 · External reference
Enhanced characterization of histones using 193 nm ultraviolet photodissociation and proton transfer charge reduction
10.1021/acs.analchem.2c05765 · 2023 · External reference
Impact of charge reduction on sequence coverage of proteins by 193 nm ultraviolet photodissociation
10.1021/jasms.5c00230 · 2025 · External reference
Characterization of unbranched ubiquitin tetramers by combining ultraviolet photodissociation with proton transfer charge reduction reactions
10.1021/acs.analchem.3c02618 · 2023 · External reference
Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD)
10.1073/pnas.1321458111 · 2014 · External reference
Facilitating protein disulfide mapping by a combination of pepsin digestion, electron transfer higher energy dissociation (EThcD), and a dedicated search algorithm SlinkS
10.1074/mcp.o114.039057 · 2014 · External reference
Leveraging ion–ion and ion–photon activation to improve the sequencing of proteins carrying multiple disulfide bonds: the human serum albumin case study
10.1021/jasms.4c00391 · 2024 · External reference
Sequential ion–ion reactions for enhanced gas-phase sequencing of large intact proteins in a tribrid orbitrap mass spectrometer
10.1021/jasms.1c00062 · 2021 · External reference
Enhanced payload localization in antibody–drug conjugates using a middle-down mass spectrometry approach with proton transfer charge reduction
10.1021/acs.analchem.4c03872 · 2024 · External reference
Unresolved reference
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