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References from Highly sensitive detection of exosomal miR-122 with CRISPR-Dx for precise HCC diagnosis. Local targets link to admitted publications; unresolved targets remain external evidence.
Global burden of primary liver cancer in 2020 and predictions to 2040
10.1016/j.jhep.2022.08.021 · 2022 · External reference
A dual-locked hepatic-targeting fluorescent probe for hepatocellular carcinoma imaging with HClO and β-galactosidase activation
10.1016/j.snb.2025.138417 · 2025 · External reference
Dual-function CRISPR/Cas12a assisted strand displacement reaction with RuHex-loaded DNA condensates for ultrasensitive electrochemical detection of hepatocellular carcinoma mRNA
10.1016/j.bios.2026.118610 · 2026 · External reference
10.3390/genes15101313
10.3390/genes15101313 · External reference
Feasibility of terahertz imaging for discrimination of human hepatocellular carcinoma
10.4251/wjgo.v11.i2.153 · 2019 · External reference
MiR-122 inhibits epithelial-mesenchymal transition in hepatocellular carcinoma by targeting Snail1 and Snail2 and suppressing WNT/β-cadherin signaling pathway
10.1016/j.yexcr.2017.09.010 · 2017 · External reference
The evolving epidemiology of hepatocellular carcinoma: a global perspective
10.1586/17474124.2015.1028363 · 2015 · External reference
Serum and exosome long non coding RNAs as potential biomarkers for hepatocellular carcinoma
10.7150/jca.24978 · 2018 · External reference
Diagnostic utility of plasma lncRNA small nucleolar RNA host gene 1 in patients with hepatocellular carcinoma
2018 · External reference
miR-122 – a key factor and therapeutic target in liver disease
10.1016/j.jhep.2014.10.004 · 2015 · External reference
Dual catalytic hairpin assembly-powered DNA walker activation of CRISPR/Cas12a for label-free electrochemical detection of hepatocellular carcinoma biomarkers
10.1016/j.snb.2025.138462 · 2025 · External reference
Circulating microRNAs (miR‐16, miR‐22, miR‐122) expression and early diagnosis of hepatocellular carcinoma
10.1002/jcla.24541 · 2022 · External reference
Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma
10.1016/j.ejca.2013.06.002 · 2013 · External reference
Early diagnostic evaluation of miR-122 and miR-224 as biomarkers for hepatocellular carcinoma
10.1016/j.gendis.2017.10.003 · 2017 · External reference
Antitumor function of microRNA-122 against hepatocellular carcinoma
10.1007/s00535-014-0932-4 · 2014 · External reference
Breaking barriers: overcoming low abundance of miR-122 with E-DDM for precise detection in HCC patients
10.1016/j.snb.2024.135372 · 2024 · External reference
Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
10.1186/s13045-015-0220-7 · 2015 · External reference
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
10.1038/onc.2009.211 · 2009 · External reference
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
10.1172/jci63455 · 2012 · External reference
An entropy-driven autocatalysis-regulated Signal-On CRISPR/Cas12a biosensor supported by DNA triangular prism scaffold
10.1021/acs.analchem.6c01471 · 2026 · External reference
DNA triangular prism nanostructure and CRISPR/Cas12a empowered electrochemical biosensor for dual detection of alpha-fetoprotein and microRNA 122
10.1016/j.bios.2025.117697 · 2025 · External reference
Electrochemical biosensor based on a tetrahedral DNA nanostructure and an “AND” logic gate-regulated Cascade amplification system for parallel detection of dual disease biomarkers
10.1021/acssensors.5c02167 · 2025 · External reference
Proximity-induced amplification cascade for accurate and sensitive colorimetric detection of tumor-derived exosomes
10.1016/j.snb.2025.137832 · 2025 · External reference
High-throughput screening of bladder cancer exosome biomarkers by barcodes integrated herringbone microfluidics
10.1016/j.bios.2026.118545 · 2026 · External reference
Early cancer detection based on exosome biosensors in biological samples
10.1016/j.snb.2023.134886 · 2024 · External reference
Biosensor-based methods for exosome detection with applications to disease diagnosis
10.1016/j.bios.2025.117362 · 2025 · External reference
CRISPR/Cas13a triggered-DNA walker amplified SERS sensor for ultrasensitive detection of cancer-related exosomal miRNA
10.1016/j.bios.2025.117924 · 2025 · External reference
The role of Exosomal miRNAs in cancer
10.1186/s12967-021-03215-4 · 2022 · External reference
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
10.3402/jev.v3.23743 · 2014 · External reference
Colorimetric PCR based on pyrophosphate displacement
10.1021/acs.analchem.6c01682 · 2026 · External reference
Quantitative analysis of zeptomole microRNAs based on isothermal ramification amplification
10.1261/rna.1555209 · 2009 · External reference
Advancements of CRISPR technology in public health-related analysis
10.1016/j.bios.2024.116449 · 2024 · External reference
The CRISPR–Cas toolbox for analytical and diagnostic assay development
10.1039/d1cs00098e · 2021 · External reference
Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
10.1039/d2cs00594h · 2023 · External reference
CRISPR-Cas based virus detection: recent advances and perspectives
10.1016/j.bios.2021.113541 · 2021 · External reference
