Research graph
References from Age-dependent brain mechanics are linked to microstructural changes. Local targets link to admitted publications; unresolved targets remain external evidence.
The human brain in numbers: a linearly scaled-up primate brain
10.3389/neuro.09.031.2009 · 2009 · External reference
Unresolved reference
2000 · External reference
Diffuse axonal injury and traumatic coma in the primate
10.1002/ana.410120611 · 1982 · External reference
Modified bilston nonlinear viscoelastic model for finite element head injury studies
10.1115/1.2264393 · 2006 · External reference
Biomechanics of traumatic brain injury
10.1016/j.cma.2008.06.006 · 2008 · External reference
Actomyosin-mediated cellular tension drives increased tissue stiffness and beta-catenin activation to induce epidermal hyperplasia and tumor growth
10.1016/j.ccr.2011.05.008 · 2011 · External reference
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
10.1038/onc.2012.202 · 2013 · External reference
Compression stiffening of brain and its effect on mechanosensing by glioma cells
10.1088/1367-2630/16/7/075002 · 2014 · External reference
Bioengineered 3D brain tumor model to elucidate the effects of matrix stiffness on glioblastoma cell behavior using PEG-based hydrogels
10.1021/mp5000828 · 2014 · External reference
Material–modeling and structural–mechanics aspects of the traumatic brain injury problem
10.1108/15736101011080097 · 2010 · External reference
Computation of axonal elongation in head trauma finite element simulation
10.1016/j.jmbbm.2011.06.007 · 2011 · External reference
A tissue-level anisotropic criterion for brain injury based on microstructural axonal deformation
10.1016/j.jmbbm.2011.09.012 · 2012 · External reference
The influence of anisotropy on brain injury prediction
10.1016/j.jbiomech.2013.12.036 · 2014 · External reference
The mechanics of decompressive craniectomy: Personalized simulations
10.1016/j.cma.2016.08.011 · 2017 · External reference
Biomechanical modeling and computer simulation of the brain during neurosurgery
10.1002/cnm.3250 · 2019 · External reference
Fifty years of brain tissue mechanical testing: from in vitro to in vivo investigations
2010 · External reference
Fifty shades of brain: A review on the mechanical testing and modeling of brain tissue
10.1007/s11831-019-09352-w · 2020 · External reference
A comprehensive analysis of inconsistencies in the brain’s conventional ex vivo mechanical experiments
10.1007/s10439-025-03765-4 · 2025 · External reference
Constitutive modelling of brain tissue: Experiment and theory
10.1016/s0021-9290(97)00092-4 · 1997 · External reference
Mechanical properties of brain tissue in tension
10.1016/s0021-9290(01)00234-2 · 2002 · External reference
Biomechanics of brain tissue
10.1016/j.actbio.2010.06.035 · 2011 · External reference
Mechanical characterization of brain tissue in compression at dynamic strain rates
10.1016/j.jmbbm.2012.01.022 · 2012 · External reference
A comprehensive experimental study on material properties of human brain tissue
10.1016/j.jbiomech.2013.09.001 · 2013 · External reference
Compressive properties and constitutive modeling of different regions of 8-week-old pediatric porcine brain under large strain and wide strain rates
10.1016/j.jmbbm.2018.09.010 · 2019 · External reference
Mechanical characterization of brain tissue in tension at dynamic strain rates
10.1016/j.jmbbm.2012.07.015 · 2014 · External reference
Mechanical characterization of human brain tissue
10.1016/j.actbio.2016.10.036 · 2017 · External reference
Biphasic analysis of rat brain slices under creep indentation shows nonlinear tension-compression behavior
10.1016/j.jmbbm.2018.08.043 · 2019 · External reference
Tension strain-softening and compression strain-stiffening behavior of brain white matter
10.1007/s10439-020-02541-w · 2021 · External reference
Correlating the microstructural architecture and macrostructural behaviour of the brain
10.1016/j.actbio.2022.08.034 · 2022 · External reference
Regional, directional, and age-dependent properties of the brain undergoing large deformation
10.1115/1.1449907 · 2002 · External reference
Towards child versus adult brain mechanical properties
10.1016/j.jmbbm.2011.09.013 · 2012 · External reference
Viscoelastic properties of the rat brain in the sagittal plane: Effects of anatomical structure and age
10.1007/s10439-011-0394-2 · 2012 · External reference
CNS cell distribution and axon orientation determine local spinal cord mechanical properties
10.1016/j.bpj.2015.03.039 · 2015 · External reference
Do human brain white matter and brain stem structures show direction-dependent mechanical behavior?
10.1016/j.actbio.2025.04.004 · 2025 · External reference
Anisotropic constitutive equations and experimental tensile behavior of brain tissue
10.1007/s10237-005-0007-9 · 2006 · External reference
Dynamic mechanical response of bovine gray matter and white matter brain tissues under compression
10.1016/j.jbiomech.2009.01.023 · 2009 · External reference
Region and species dependent mechanical properties of adolescent and young adult brain tissue
10.1038/s41598-017-13727-z · 2017 · External reference
Measurements of mechanical anisotropy in brain tissue and implications for transversely isotropic material models of white matter
10.1016/j.jmbbm.2013.04.007 · 2013 · External reference
Characterizing white matter tissue in large strain via asymmetric indentation and inverse finite element modeling
10.1016/j.jmbbm.2016.09.020 · 2017 · External reference
Topological turning points across the human lifespan
10.1038/s41467-025-65974-8 · 2025 · External reference
Prenatal and postnatal growth and development of the central nervous system of the pig
10.1098/rspb.1967.0002 · 1967 · External reference
Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights
10.1002/ana.410040410 · 1978 · External reference
Physical biology of human brain development
10.3389/fncel.2015.00257 · 2015 · External reference
Modeling the life cycle of the human brain
10.1016/j.cobme.2019.12.009 · 2020 · External reference
Ageing and the brain: This article is part of a series on ageing edited by professor chris bulpitt
10.1136/pgmj.2005.036665 · 2006 · External reference
The influence of physiological aging and atrophy on brain viscoelastic properties in humans
10.1371/journal.pone.0023451 · 2011 · External reference
Brain elastography in aging relates to fluid/solid trendlines
10.1088/1361-6560/ad4446 · 2024 · External reference
Average biomechanical responses of the human brain grouped by age and sex
10.1007/s10439-025-03725-y · 2025 · External reference
Data-driven depiction of aging related physiological volume shrinkage in brain white matter: An image processing based three-dimensional micromechanical model
2025 · External reference
High-resolution magnetic resonance elastography reveals differences in subcortical gray matter viscoelasticity between young and healthy older adults
10.1016/j.neurobiolaging.2018.01.010 · 2018 · External reference
Magnetic resonance elastography of brain: Comparison between anisotropic and isotropic stiffness and its correlation to age
10.1002/mrm.27757 · 2019 · External reference
Measuring the effects of aging and sex on regional brain stiffness with MR elastography in healthy older adults
10.1016/j.neuroimage.2015.02.016 · 2015 · External reference
Mouse brain elastography changes with sleep/wake cycles, aging, and Alzheimer’s disease
10.1016/j.neuroimage.2024.120662 · 2024 · External reference
In vivo wideband MR elastography for assessing age-related viscoelasticity changes of the human brain
10.1016/j.actbio.2026.02.002 · 2026 · External reference
Microstructural changes in locus coeruleus-cortical projections in aged bonnet macaques are independent of myelin loss
10.1016/j.neurobiolaging.2025.09.009 · 2026 · External reference
Microstructural maturation of the human brain from childhood to adulthood
10.1016/j.neuroimage.2007.12.053 · 2008 · External reference
Maturation along white matter tracts in human brain using a diffusion tensor surface model tract-specific analysis
10.3389/fnana.2016.00009 · 2016 · External reference
White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction
10.1016/j.neuroimage.2020.117441 · 2021 · External reference
Diffusion MRI microstructure markers of changes in the human brain across the lifespan using constrained spherical deconvolution and fixel-based techniques
10.1002/hbm.70403 · 2025 · External reference
Maturation-dependent response of the piglet brain to scaled cortical impact
10.3171/jns.2000.93.3.0455 · 2000 · External reference
Age-dependent changes in material properties of the brain and braincase of the rat
10.1089/089771503770802853 · 2003 · External reference
Age-dependent regional mechanical properties of the rat hippocampus and cortex
10.1115/1.4000164 · 2010 · External reference
A detailed viscoelastic characterization of the P17 and adult rat brain
10.1089/neu.2010.1604 · 2011 · External reference
Age-dependence of intracranial viscoelastic properties in living rats
10.1016/j.jmbbm.2010.12.012 · 2011 · External reference
Viscoelastic mapping of mouse brain tissue: Relation to structure and age
10.1016/j.jmbbm.2020.104159 · 2021 · External reference
Machine learning reveals correlations between brain age and mechanics
10.1016/j.actbio.2024.10.003 · 2024 · External reference
Age-dependent material properties of the porcine cerebrum: effect on pediatric inertial head injury criteria
10.1016/s0021-9290(98)00122-5 · 1998 · External reference
The networking brain: How extracellular matrix, cellular networks, and vasculature shape the in vivo mechanical properties of the brain
2024 · External reference
Least squares quantization in pcm
10.1109/tit.1982.1056489 · 1982 · External reference
K-means++: the advantages of careful seeding
2007 · External reference
Large deformation isotropic elasticity – on the correlation of theory and experiment for incompressible rubberlike solids
1972 · External reference
Hyperelastic modelling of arterial layers with distributed collagen fibre orientations
10.1098/rsif.2005.0073 · 2006 · External reference
Robust statistical modeling using the t distribution
1989 · External reference
The no-u-turn sampler: adaptively setting path lengths in Hamiltonian Monte Carlo
2014 · External reference
Probabilistic programming in python using PyMC3
10.7717/peerj-cs.55 · 2016 · External reference
Unresolved reference
1988 · External reference
The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations
10.1037/0022-3514.51.6.1173 · 1986 · External reference
Mediation analysis
10.1146/annurev.psych.58.110405.085542 · 2007 · External reference
Addressing moderated mediation hypotheses: theory, methods, and prescriptions
10.1080/00273170701341316 · 2007 · External reference
Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models
10.3758/brm.40.3.879 · 2008 · External reference
Bootstrap methods: Another look at the jackknife
10.1214/aos/1176344552 · 1979 · External reference
Neocortical cell counts in normal human adult aging
10.1002/ana.410210603 · 1987 · External reference
Changes in weight and compositions of major membrane components of human brain during the span of adult human life of swedes
10.1007/s004010050717 · 1997 · External reference
Brain morphometry and cognitive performance in normal brain aging: Age- and sex-related structural and functional changes
10.3389/fnagi.2021.713680 · 2022 · External reference
Brain growth of the domestic pig (sus scrofa) from 2 to 24 weeks of age: A longitudinal MRI study
10.1159/000339311 · 2012 · External reference
Brain development in children and adolescents: Insights from anatomical magnetic resonance imaging
10.1016/j.neubiorev.2006.06.001 · 2006 · External reference
A meta-analysis of sex differences in human brain structure
10.1016/j.neubiorev.2013.12.004 · 2014 · External reference
Sexual dimorphism and asymmetries in the gray–white composition of the human cerebrum
10.1016/s1053-8119(03)00034-x · 2003 · External reference
Sexual dimorphism of brain developmental trajectories during childhood and adolescence
10.1016/j.neuroimage.2007.03.053 · 2007 · External reference
Developmental trajectories of the fronto-temporal lobes from infancy to early adulthood in healthy individuals
10.1159/000345152 · 2012 · External reference
A voxel-based morphometric study of age-and sex-related changes in white matter volume in the normal aging brain
2016 · External reference
Preservation of neuronal number despite age-related cortical brain atrophy in elderly subjects without alzheimer disease
10.1097/nen.0b013e31818fc72f · 2008 · External reference
Structural brain changes in aging: courses, causes and cognitive consequences
10.1515/revneuro.2010.21.3.187 · 2010 · External reference
Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits
10.1093/cercor/12.11.1171 · 2002 · External reference
Age-related changes of astorocytes, oligodendrocytes and microglia in the mouse hippocampal CA1 sector
10.1016/j.mad.2007.01.005 · 2007 · External reference
Stereological analysis of astrocyte and microglia in aging mouse hippocampus
10.1016/s0197-4580(98)00088-8 · 1998 · External reference
Age and gender effects on microglia and astrocyte numbers in brains of mice
10.1016/s0006-8993(02)03475-3 · 2002 · External reference
Age-related white matter atrophy in the human brain
10.1111/j.1749-6632.1992.tb27462.x · 1992 · External reference
Effects of aging on myelinated nerve fibers in monkey primary visual cortex
10.1002/(sici)1096-9861(20000410)419:3<364::aid-cne8>3.0.co;2-r · 2000 · External reference
Marked loss of myelinated nerve fibers in the human brain with age
10.1002/cne.10714 · 2003 · External reference
Aging and the human neocortex
10.1016/s0531-5565(02)00151-1 · 2003 · External reference
White matter loss in healthy ageing: A postmortem analysis
10.1016/j.neurobiolaging.2007.10.015 · 2009 · External reference
Maturation of white matter in the human brain: a review of magnetic resonance studies
10.1016/s0361-9230(00)00434-2 · 2001 · External reference
Embryonic development and myelination of the corpus callosum
10.1007/978-3-031-38114-0_2 · 2023 · External reference
Cognition through the lifespan: mechanisms of change
10.1016/j.tics.2006.01.007 · 2006 · External reference
Regional differences in synaptogenesis in human cerebral cortex
10.1002/(sici)1096-9861(19971020)387:2<167::aid-cne1>3.0.co;2-z · 1997 · External reference
Cellular scaling rules for rodent brains
10.1073/pnas.0604911103 · 2006 · External reference
Juvenile neurogenesis makes essential contributions to adult brain structure and plays a sex-dependent role in fear memories
2012 · External reference
Quantitative analysis of postnatal neurogenesis and neuron number in the macaque monkey dentate gyrus
10.1111/j.1460-9568.2009.07061.x · 2010 · External reference
Postnatal plasticity in the olfactory system of the juvenile swine brain
10.1007/s00429-025-03008-1 · 2025 · External reference
Brain stiffness increases with myelin content
10.1016/j.actbio.2016.07.040 · 2016 · External reference
Unraveling the local relation between tissue composition and human brain mechanics through machine learning
2021 · External reference
Brain maturation is associated with increasing tissue stiffness and decreasing tissue fluidity
10.1016/j.actbio.2019.08.036 · 2019 · External reference
Structural anisotropy vs. mechanical anisotropy: the contribution of axonal fibers to the material properties of brain white matter
10.1007/s10439-020-02643-5 · 2021 · External reference
An integrated approach to investigate age-related modifications of morphological, mechanical and structural properties of type I collagen
10.1016/j.actbio.2021.10.020 · 2022 · External reference
Age-related changes in dermal collagen physical properties in human skin
10.1371/journal.pone.0292791 · 2023 · External reference
Quantification of age-related changes in the structure and mechanical function of skin with multiscale imaging
10.1007/s11357-024-01199-9 · 2024 · External reference
Mediation analysis in psychosomatic medicine research
2011 · External reference
Mediation analysis in medical research
2023 · External reference
Modulation of metabolic, inflammatory and fibrotic pathways by semaglutide in metabolic dysfunction-associated steatohepatitis
10.1038/s41591-025-03799-0 · 2025 · External reference