Research graph
References from 4-1BB (CD137) and radiation therapy: A case report and literature review. Local targets link to admitted publications; unresolved targets remain external evidence.
Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity
10.1158/2326-6066.cir-13-0031-t · 2014 · External reference
Interleukin-7 and anti-programmed cell death 1 antibody have differing effects to reverse sepsis-induced immunosuppression
10.1097/shk.0000000000000317 · 2015 · External reference
Combining radiation and immunotherapy for synergistic antitumor therapy
2009 · External reference
Combining radiotherapy and immunotherapy: A revived partnership
10.1016/j.ijrobp.2005.06.032 · 2005 · External reference
Systemic effects of local radiotherapy
10.1016/s1470-2045(09)70082-8 · 2009 · External reference
Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies
10.1158/0008-5472.can-12-0210 · 2012 · External reference
Local tumor treatment in combination with systemic ipilimumab immunotherapy prolongs overall survival in patients with advanced malignant melanoma
10.1158/2326-6066.cir-15-0156 · 2016 · External reference
Abscopal effects of radiotherapy on advanced melanoma patients who progressed after ipilimumab immunotherapy
10.4161/onci.28780 · 2014 · External reference
Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model
10.1371/journal.pone.0101764 · 2014 · External reference
4-1BB aptamer-based immunomodulation enhances the therapeutic index of radiation therapy in murine tumor models
10.1016/j.ijrobp.2016.05.013 · 2016 · External reference
Augmented antitumor effects of radiation therapy by 4-1BB antibody (BMS-469492) treatment
2006 · External reference
4-1BB agonists: Multi-potent potentiators of tumor immunity
10.3389/fonc.2015.00117 · 2015 · External reference
Combination of 4-1BB agonist and PD-1 antagonist promotes antitumor effector/memory CD8 T cells in a poorly immunogenic tumor model
10.1158/2326-6066.cir-14-0118 · 2015 · External reference
Therapeutic PD-1 pathway blockade augments with other modalities of immunotherapy T-cell function to prevent immune decline in ovarian cancer
10.1158/0008-5472.can-13-1550 · 2013 · External reference
Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma
10.1007/s00262-016-1843-4 · 2016 · External reference
Use of oligonucleotide aptamer ligands to modulate the function of immune receptors
10.1158/1078-0432.ccr-12-2067 · 2013 · External reference
