Research graph
References from Differential effects of stearic, palmitic and oleic acid enriched diets on gut microbiome, bile acid and cholesterol metabolism in mildly hypercholesterolemic post-menopausal females: A secondary analysis of a randomized controlled trial. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Dietary Fats and Cardiovascular Disease: A Presidential Advisory From the American Heart Association
10.1161/cir.0000000000000510 · 2017 · External reference
2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2026 · External reference
Saturated Fats and Health: A Reassessment and Proposal for Food-Based Recommendations: JACC State-of-the-Art Review
10.1016/j.jacc.2020.05.077 · 2020 · External reference
Impact of Replacement of Individual Dietary SFAs on Circulating Lipids and Other Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials in Humans
10.1093/advances/nmab143 · 2022 · External reference
Dietary Fat and Risk of Cardiovascular Disease: Recent Controversies and Advances
10.1146/annurev-nutr-071816-064614 · 2017 · External reference
Saturated Fatty Acid Chain Length and Risk of Cardiovascular Disease: A Systematic Review
10.3390/nu15010030 · 2023 · External reference
Comparison of diets enriched in stearic, oleic, and palmitic acids on inflammation, immune response, cardiometabolic risk factors, and fecal bile acid concentrations in mildly hypercholesterolemic postmenopausal women-randomized crossover trial
10.1093/ajcn/nqz095 · 2019 · External reference
Dietary stearic acid and risk of cardiovascular disease: intake, sources, digestion, and absorption
10.1007/s11745-005-1485-y · 2005 · External reference
Palmitic Acid Versus Stearic Acid: Effects of Interesterification and Intakes on Cardiometabolic Risk Markers—A Systematic Review
10.3390/nu12030615 · 2020 · External reference
Cardiovascular disease risk of dietary stearic acid compared with trans, other saturated, and unsaturated fatty acids: a systematic review
10.3945/ajcn.2009.27661 · 2010 · External reference
Effects of stearic acid on plasma lipid and lipoproteins in humans
10.1007/s11745-005-1486-x · 2005 · External reference
Stearic acid metabolism in human health and disease
10.1016/j.clnu.2024.12.012 · 2025 · External reference
Metabolism of dietary stearic acid relative to other fatty acids in human subjects
1994 · External reference
Influence of stearic acid on cholesterol metabolism relative to other long-chain fatty acids
10.1093/ajcn/60.6.986s · 1994 · External reference
Effect of dietary stearic acid on plasma cholesterol and lipoprotein levels
10.1056/nejm198805123181905 · 1988 · External reference
Influence of linoleic acid on desaturation and uptake of deuterium-labeled palmitic and stearic acids in humans
10.1016/0005-2760(93)90068-k · 1993 · External reference
Stearic acid absorption and its metabolizable energy value are minimally lower than those of other fatty acids in healthy men fed mixed diets
10.1093/jn/133.12.4129 · 2003 · External reference
Comparison of the Postprandial Metabolic Fate of U-(13)C Stearic Acid and U-(13)C Oleic Acid in Postmenopausal Women
10.1161/atvbaha.120.315260 · 2020 · External reference
Dietary Lipids, Gut Microbiota, and Their Metabolites: Insights from Recent Studies
10.3390/nu17040639 · 2025 · External reference
Omega-3 fatty acids and the gut microbiome: a new frontier in cardiovascular disease prevention
10.1007/s44337-025-00212-0 · 2025 · External reference
Bile acid metabolism and signaling: Emerging pharmacological targets of dietary polyphenols
10.1016/j.pharmthera.2023.108457 · 2023 · External reference
Review: microbial transformations of human bile acids
10.1186/s40168-021-01101-1 · 2021 · External reference
Gut microbiota derived bile acid metabolites maintain the homeostasis of gut and systemic immunity
10.3389/fimmu.2023.1127743 · 2023 · External reference
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets
10.1038/s41392-024-01811-6 · 2024 · External reference
Bile acids and their receptors in metabolic disorders
10.1016/j.plipres.2021.101094 · 2021 · External reference
Microbial impact on cholesterol and bile acid metabolism: current status and future prospects
10.1194/jlr.r088989 · 2019 · External reference
Metabolism of cholesterol and bile acids by the gut microbiota
10.3390/pathogens3010014 · 2013 · External reference
Effect of Gut Microbiota on Blood Cholesterol: A Review on Mechanisms
10.3390/foods12234308 · 2023 · External reference
The bile acid-gut microbiota axis: A central hub for physiological regulation and a novel therapeutic target for metabolic diseases
10.1016/j.biopha.2025.118182 · 2025 · External reference
The intestinal microbiota regulates host cholesterol homeostasis
10.1186/s12915-019-0715-8 · 2019 · External reference
High stearic acid diet modulates gut microbiota and aggravates acute graft-versus-host disease
10.1038/s41392-021-00600-9 · 2021 · External reference
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis
10.1038/s41467-023-41074-3 · 2023 · External reference
Stearic acid prevent alcohol-induced liver damage by regulating the gut microbiota
10.1016/j.foodres.2022.111095 · 2022 · External reference
Dietary stearic acid alters gallbladder bile acid composition in hamsters fed cereal-based diets
10.1093/jn/131.10.3119 · 2002 · External reference
Different typical dietary lipid consumption affects the bile acid metabolism and the gut microbiota structure: an animal trial using Sprague-Dawley rats
10.1002/jsfa.11661 · 2022 · External reference
Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
10.1038/s41575-021-00566-7 · 2022 · External reference
Insulin and Bile Acids in Cholesterol Homeostasis: New Players in Diabetes-Associated Atherosclerosis
10.1161/circulationaha.122.058883 · 2022 · External reference
The microbiome modulating activity of bile acids
10.1080/19490976.2020.1732268 · 2020 · External reference
Bile acids as modulators of gut microbiota composition and function
10.1080/19490976.2023.2172671 · 2023 · External reference
Cholestyramine, a Bile Acid Sequestrant, Increases Cecal Short Chain Fatty Acids and Intestinal Immunoglobulin A in Mice
10.1248/bpb.b19-00923 · 2020 · External reference
Unresolved reference
External reference
Cranberries attenuate animal-based diet-induced changes in microbiota composition and functionality: a randomized crossover controlled feeding trial
10.1016/j.jnutbio.2018.08.019 · 2018 · External reference
Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions
10.1016/s0022-2275(20)38331-0 · 1989 · External reference
An isotope-labeled chemical derivatization method for the quantitation of short-chain fatty acids in human feces by liquid chromatography-tandem mass spectrometry
10.1016/j.aca.2014.11.015 · 2015 · External reference
Deuterium uptake and plasma cholesterol precursor levels correspond as methods for measurement of endogenous cholesterol synthesis in hypercholesterolemic women
10.1007/s11745-000-0616-9 · 2000 · External reference
Hydrogenated fat consumption affects cholesterol synthesis in moderately hypercholesterolemic women
10.1016/s0022-2275(20)32392-0 · 2000 · External reference
Alterations in cholesterol absorption/synthesis markers characterize Framingham offspring study participants with CHD
10.1194/jlr.p900039-jlr200 · 2009 · External reference
DIABLO: an integrative approach for identifying key molecular drivers from multi-omics assays
10.1093/bioinformatics/bty1054 · 2019 · External reference
Microbiota-derived bile acid metabolic enzymes and their impacts on host health
10.1016/j.cellin.2025.100265 · 2025 · External reference
Interactions between Obesity Status and Dietary Intake of Monounsaturated and Polyunsaturated Oils on Human Gut Microbiome Profiles in the Canola Oil Multicenter Intervention Trial (COMIT)
10.3389/fmicb.2016.01612 · 2016 · External reference
Replacing saturated fatty acids with polyunsaturated fatty acids increases the abundance of Lachnospiraceae and is associated with reduced total cholesterol levels-a randomized controlled trial in healthy individuals
10.1186/s12944-022-01702-1 · 2022 · External reference
Quantification of Human Microbiome Stability Over 6 Months: Implications for Epidemiologic Studies
10.1093/aje/kwy064 · 2018 · External reference
Microbial functional diversity and redundancy: moving forward
2024 · External reference
Investigation of Bile Salt Hydrolase Activity in Human Gut Bacteria Reveals Production of Conjugated Secondary Bile Acids
2025 · External reference
Effects of Prevotella copri on insulin, gut microbiota and bile acids
10.1080/19490976.2024.2340487 · 2024 · External reference
Prevotella: A Key Player in Ruminal Metabolism
10.3390/microorganisms11010001 · 2022 · External reference
Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota
10.3390/nu15092211 · 2023 · External reference
Butyrate-producing human gut symbiont, Clostridium butyricum, and its role in health and disease
10.1080/19490976.2021.1907272 · 2021 · External reference
Microbial Fermentation of Dietary Protein: An Important Factor in Diet-Microbe-Host Interaction
10.3390/microorganisms7010019 · 2019 · External reference
Another renaissance for bile acid gastrointestinal microbiology
10.1038/s41575-024-00896-2 · 2024 · External reference
Bile acids and the gut microbiota: metabolic interactions and impacts on disease
10.1038/s41579-022-00805-x · 2023 · External reference
Interactions between Bacteria and Bile Salts in the Gastrointestinal and Hepatobiliary Tracts
10.3389/fmed.2017.00163 · 2017 · External reference
Interactions between gut bacteria and bile in health and disease
10.1016/j.mam.2017.06.002 · 2017 · External reference
The Mechanism of Antimicrobial Activity of Conjugated Bile Acids against Lactic Acid Bacilli
10.3390/microorganisms11071823 · 2023 · External reference
Antimicrobial and healing efficacy of bile salts with insights into cytotoxic activity
10.1038/s41598-025-30294-w · 2025 · External reference
Leptin induces the hepatic high density lipoprotein receptor scavenger receptor B type I (SR-BI) but not cholesterol 7alpha-hydroxylase (Cyp7a1) in leptin-deficient (ob/ob) mice
10.1074/jbc.m302645200 · 2003 · External reference
Bile acids in glucose metabolism in health and disease
10.1084/jem.20171965 · 2018 · External reference
Acute effects of dietary fat composition on postprandial plasma bile acid and cholecystokinin concentrations in healthy premenopausal women
10.1079/bjn2001431 · 2001 · External reference
The gut microbiota-bile acid axis in cholestatic liver disease
10.1186/s10020-024-00830-x · 2024 · External reference
Bile acid-induced negative feedback regulation of the human ileal bile acid transporter
10.1002/hep.20295 · 2004 · External reference
Bile acid transporters in health and disease
10.1080/00498250802040584 · 2008 · External reference
Novel insights into the organic solute transporter alpha/beta, OSTα/β: From the bench to the bedside
10.1016/j.pharmthera.2020.107542 · 2020 · External reference
OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids
10.2741/3416 · 2009 · External reference
Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
10.1111/j.1365-2796.2006.01731.x · 2006 · External reference
Revisiting Human Cholesterol Synthesis and Absorption: The Reciprocity Paradigm and its Key Regulators
10.1007/s11745-015-4096-7 · 2016 · External reference
Cholesterol metabolism: molecular mechanisms, biological functions, diseases, and therapeutic targets
10.1186/s43556-025-00321-3 · 2025 · External reference
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways
10.7554/elife.07999 · 2015 · External reference
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses
10.1016/j.cell.2012.06.054 · 2012 · External reference
Dietary stearic acid reduces cholesterol absorption and increases endogenous cholesterol excretion in hamsters fed cereal-based diets
10.1093/jn/130.5.1232 · 2000 · External reference
Dietary stearic acid reduces plasma and hepatic cholesterol concentrations without increasing bile acid excretion in cholesterol-fed hamsters
10.1093/jn/127.6.1148 · 1997 · External reference
