Research graph
References from Letter to the Editor: Plasma folate may not capture the intracellular steps that determine fluoropyrimidine toxicity. Local targets link to admitted publications; unresolved targets remain external evidence.
One-carbon metabolism and chemotherapy-induced toxicities in patients with stage II-III colorectal cancer: a prospective cohort study
10.1016/j.ajcnut.2026.101457 · 2026 · External reference
Folate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors
10.1016/j.mam.2012.07.006 · 2013 · External reference
Vitamin B12, folate, and the methionine remethylation cycle: biochemistry, pathways, and regulation
10.1002/jimd.12009 · 2019 · External reference
Folates as adjuvants to anticancer agents: chemical rationale and mechanism of action
10.1016/j.critrevonc.2016.08.001 · 2016 · External reference
The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates
10.1158/0008-5472.can-04-2810 · 2005 · External reference
The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites
10.1158/1535-7163.mct-04-0291 · 2005 · External reference
Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C to T polymorphism
10.1161/circulationaha.105.580332 · 2006 · External reference
Plasma deoxyuridine as a surrogate marker for toxicity and early clinical response in patients with metastatic colorectal cancer after 5-FU-based therapy in combination with arfolitixorin
10.1007/s00280-020-04173-2 · 2021 · External reference
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients
10.1111/j.1365-2125.2006.02710.x · 2007 · External reference
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for dihydropyrimidine dehydrogenase genotype and fluoropyrimidine dosing: 2017 update
10.1002/cpt.911 · 2018 · External reference
