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References from Adeno-associated virus-mediated epithelial IL-33 silencing attenuates type 2 airway inflammation. Local targets link to admitted publications; unresolved targets remain external evidence.
Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells
10.1038/nature08636 · 2010 · External reference
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
10.1016/j.immuni.2011.12.020 · 2012 · External reference
A large-scale, consortium-based genomewide association study of asthma
10.1056/nejmoa0906312 · 2010 · External reference
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
10.1038/ng.888 · 2011 · External reference
Interleukin-33 signaling controls the development of iron-recycling macrophages
10.1016/j.immuni.2020.03.006 · 2020 · External reference
Emerging functions of IL-33 in homeostasis and immunity
10.1146/annurev-immunol-101320-124243 · 2022 · External reference
Interleukin-33 and the function of innate lymphoid cells
10.1016/j.it.2012.04.005 · 2012 · External reference
Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
10.1038/s41598-023-36642-y · 2023 · External reference
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex
10.1183/13993003.02210-2022 · 2023 · External reference
Epithelial barriers in allergy and asthma
10.1016/j.jaci.2020.04.010 · 2020 · External reference
Airway epithelial cells as drivers of severe asthma pathogenesis
10.1016/j.mucimm.2025.03.003 · 2025 · External reference
Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation
10.1038/ncomms3675 · 2013 · External reference
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: a randomized clinical trial
10.1016/j.jaci.2021.03.044 · 2021 · External reference
Efficacy and safety of Itepekimab in patients with moderate-to-severe asthma
10.1056/nejmoa2024257 · 2021 · External reference
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
10.1128/jvi.72.11.8568-8577.1998 · 1998 · External reference
Adeno-associated virus and the development of adeno-associated virus vectors: a historical perspective
10.1016/j.ymthe.2004.09.011 · 2004 · External reference
Adeno-associated virus vectors preferentially transduce cells in S phase
10.1073/pnas.91.19.8915 · 1994 · External reference
Recombinant adeno-associated virus for muscle directed gene therapy
10.1038/nm0397-306 · 1997 · External reference
A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype
10.1186/1743-422x-10-74 · 2013 · External reference
Adeno-associated viral vector integration: implications for long-term efficacy and safety
10.1016/j.jtha.2024.07.012 · 2024 · External reference
Treatment of human disease by adeno-associated viral gene transfer
10.1007/s00439-006-0165-6 · 2006 · External reference
Current clinical applications of AAV-mediated gene therapy
10.1016/j.ymthe.2025.04.045 · 2025 · External reference
Utility of microminipigs for evaluating liver-mediated gene expression in the presence of neutralizing antibody against vector capsid
10.1038/s41434-020-0125-0 · 2020 · External reference
The role of interleukin-33 in pathogenesis of bronchial asthma. New experimental data
10.1134/s0006297918010029 · 2018 · External reference
Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered
10.1073/pnas.0601433103 · 2006 · External reference
Therapeutic effects of telomerase in mice with pulmonary fibrosis induced by damage to the lungs and short telomeres
10.7554/elife.31299 · 2018 · External reference
Tropism of adeno-associated virus serotypes in mouse lungs via intratracheal instillation
10.1186/s12985-024-02575-9 · 2024 · External reference
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors
10.1128/jvi.70.5.3227-3234.1996 · 1996 · External reference
Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses
10.1038/ni.3309 · 2016 · External reference
The RNA binding protein Mex-3B is required for IL-33 induction in the development of allergic airway inflammation
10.1016/j.celrep.2016.07.062 · 2016 · External reference
Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice
10.4049/jimmunol.0713433 · 2009 · External reference
Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme
10.1016/j.jaci.2007.12.1175 · 2008 · External reference
Small interfering RNA against interleukin-5 decreases airway eosinophilia and hyper-responsiveness
10.1038/gt.2008.15 · 2008 · External reference
Synergistic therapeutic effects of combined adenovirus-mediated interleukin-10 and interleukin-12 gene therapy on airway inflammation in asthmatic mice
10.1002/jgm.1408 · 2010 · External reference
Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness
10.1038/sj.mt.6300309 · 2008 · External reference
IL-33 blockade in asthma: a story of hype, hope and hindsight
10.1183/23120541.01202-2025 · 2026 · External reference
Endothelial Sox17 promotes allergic airway inflammation
10.1016/j.jaci.2019.02.034 · 2019 · External reference
The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway
10.1016/j.immuni.2015.01.016 · 2015 · External reference
Immune responses to adenovirus and adeno-associated virus in humans
10.1038/sj.gt.3300994 · 1999 · External reference
Update on the prevalence of serum antibodies (IgG and IgM) to adeno-associated virus (AAV)
10.1002/(sici)1096-9071(199911)59:3<406::aid-jmv22>3.0.co;2-n · 1999 · External reference
The prevalence of neutralizing antibodies against adeno-associated virus capsids is reduced in young Japanese individuals
10.1002/jmv.23818 · 2014 · External reference
