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References from Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals. Local targets link to admitted publications; unresolved targets remain external evidence.
Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator uhrf1
10.1002/mnfr.201100307 · 2011 · External reference
Dietary protein restriction and excess of pregnant german landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring
10.1016/j.jnutbio.2012.01.011 · 2013 · External reference
Somatic cytochrome c (CYCS) gene expression and promoter-specific DNA methylation in a porcine model of prenatal exposure to maternal dietary protein excess and restriction
10.1017/s0007114511003667 · 2012 · External reference
Genome-wide DNA methylation profiling identifies a folate-sensitive region of differential methylation upstream of ZFP57-imprinting regulator in humans
10.1096/fj.13-249029 · 2014 · External reference
Epigenetic and genetic mechanisms contribute to telomerase inhibition by EGCG
10.1002/jcb.21417 · 2008 · External reference
Glucocorticoid effects on the programming of AT1B angiotensin receptor gene methylation and expression in the rat
10.1371/journal.pone.0009237 · 2010 · External reference
Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension
10.1161/01.res.0000258855.60637.58 · 2007 · External reference
Quantitative allele-specific expression and DNA methylation analysis of H19, IGF2 and IGF2R in the human placenta across gestation reveals H19 imprinting plasticity
10.1371/journal.pone.0051210 · 2012 · External reference
Nutrition, epigenetics, and developmental plasticity: implications for understanding human disease
10.1146/annurev.nutr.012809.104751 · 2010 · External reference
Maternal nutrition induces pervasive gene expression changes but no detectable DNA methylation differences in the liver of adult offspring
10.1371/journal.pone.0090335 · 2014 · External reference
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals
10.1016/j.cell.2010.12.008 · 2010 · External reference
Sirtuins mediate mammalian metabolic responses to nutrient availability
10.1038/nrendo.2011.225 · 2012 · External reference
Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
10.1371/journal.pgen.1000602 · 2009 · External reference
Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams
10.3390/ijms141224422 · 2013 · External reference
Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet
10.1017/s204017441400035x · 2014 · External reference
Nutritional programming affects hypothalamic organization and early response to leptin
10.1210/en.2009-0893 · 2010 · External reference
Dietary choline reverses some, but not all, effects of folate deficiency on neurogenesis and apoptosis in fetal mouse brain
10.3945/jn.110.122044 · 2010 · External reference
DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation
10.1097/00008469-199411000-00004 · 1994 · External reference
Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake
10.1016/s0261-5614(98)80304-x · 1998 · External reference
DNA methylation and its implications and accessibility for neuropsychiatric therapeutics
10.1146/annurev-pharmtox-010814-124527 · 2015 · External reference
DNA methylation and memory formation
10.1038/nn.2666 · 2010 · External reference
Epigenetic mechanisms in cognition
10.1016/j.neuron.2011.05.019 · 2011 · External reference
Genistein alters methylation patterns in mice
10.1093/jn/132.8.2419s · 2002 · External reference
Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: diet–gene interactions and promoter CpG island hypermethylation in colorectal cancer
10.1007/s10552-010-9659-6 · 2011 · External reference
Metabolic effects of different protein intakes after short term undernutrition in artificially reared infant rats
10.1016/j.earlhumdev.2008.06.009 · 2009 · External reference
Placental-specific IGF2 knockout mice exhibit hypocalcemia and adaptive changes in placental calcium transport
10.1073/pnas.0911710107 · 2010 · External reference
Theoretical analysis of epigenetic cell memory by nucleosome modification
10.1016/j.cell.2007.02.053 · 2007 · External reference
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome
10.1289/ehp.8700 · 2006 · External reference
Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
10.1038/ncomms4746 · 2014 · External reference
Offspring of mothers fed a high fat diet display hepatic cell cycle inhibition and associated changes in gene expression and DNA methylation
10.1371/journal.pone.0021662 · 2011 · External reference
Dietary polyphenols may affect DNA methylation
10.1093/jn/137.1.223s · 2007 · External reference
Reversal of hypermethylation and reactivation of p16INK4a, RARβ, and MGMT genes by genistein and other isoflavones from soy
10.1158/1078-0432.ccr-05-0406 · 2005 · External reference
The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines
10.1016/j.jnutbio.2015.02.002 · 2015 · External reference
DNA methylation and expression of the folate transporter genes in colorectal cancer
10.1007/s13277-015-3228-2 · 2015 · External reference
Epigenetics and the environment: emerging patterns and implications
10.1038/nrg3142 · 2012 · External reference
You are what your dad ate
10.1016/j.cmet.2011.01.011 · 2011 · External reference
Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene
10.1096/fj.08-124768 · 2009 · External reference
Nutritional epigenomics of metabolic syndrome: new perspective against the epidemic
10.2337/diabetes.54.7.1899 · 2005 · External reference
DNA methylation in oocytes and liver of female mice and their offspring: effects of high-fat-diet-induced obesity
10.1289/ehp.1307047 · 2014 · External reference
Epigenetics: understanding how our choices lead to our diseases
2014 · External reference
EGCG inhibits growth and induces apoptosis in renal cell carcinoma through TFPI-2 overexpression
2009 · External reference
Epigenetic and phenotypic changes result from a continuous pre and post natal dietary exposure to phytoestrogens in an experimental population of mice
10.1186/1472-6793-8-17 · 2008 · External reference
Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae
10.1016/j.ydbio.2008.04.025 · 2008 · External reference
Persistent epigenetic differences associated with prenatal exposure to famine in humans
10.1073/pnas.0806560105 · 2008 · External reference
Tissue-specific DNA methylation profiles in newborns
10.1186/1868-7083-5-8 · 2013 · External reference
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways
10.1158/1078-0432.ccr-09-0558 · 2009 · External reference
Genistein downregulates onco-miR-1260b and upregulates sFRP1 and Smad4 via demethylation and histone modification in prostate cancer cells
10.1038/bjc.2014.48 · 2014 · External reference
Tissue-specific insulator function at H19/igf2 revealed by deletions at the imprinting control region
10.1093/hmg/ddu344 · 2014 · External reference
A novel CpG island set identifies Tissue-Specific methylation at developmental gene loci
10.1371/journal.pbio.0060022 · 2008 · External reference
Tet proteins can convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
10.1126/science.1210597 · 2011 · External reference
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
10.1038/ng1089 · 2003 · External reference
The role of nutrition on epigenetic modifications and their implications on health
10.1016/j.biochi.2012.06.012 · 2012 · External reference
Rethinking how DNA methylation patterns are maintained
10.1038/nrg2651 · 2009 · External reference
Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome
10.1096/fj.11-181792 · 2011 · External reference
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells
10.1038/sj.bjc.6604521 · 2008 · External reference
Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
10.1002/ijc.23590 · 2008 · External reference
Nutritional control of reproductive status in honeybees via DNA methylation
10.1126/science.1153069 · 2008 · External reference
Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids
10.1124/mol.104.008367 · 2005 · External reference
A sustained dietary change increases epigenetic variation in isogenic mice
10.1371/journal.pgen.1001380 · 2011 · External reference
Folic acid inhibits tau phosphorylation through regulation of PP2A methylation in SH-SY5Y cells
10.1007/s12603-014-0514-4 · 2015 · External reference
Epigenetic regulation of caloric restriction in aging
10.1186/1741-7015-9-98 · 2011 · External reference
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
10.1093/jn/135.6.1382 · 2005 · External reference
Feeding pregnant rats a protein-restricted diet persistently alters the methylation of specific cytosines in the hepatic PPARa promoter of the offspring
10.1017/s0007114507894438 · 2008 · External reference
10.1017/s000711450769196x
10.1017/s000711450769196x · 2007 · External reference
Curcumin is a potent DNA hypomethylation agent
10.1016/j.bmcl.2008.12.041 · 2009 · External reference
Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissues
10.1093/carcin/bgu219 · 2015 · External reference
S-adenosylmethionine: jack of all trades and master of everything?
10.1042/bst0340330 · 2006 · External reference
The dutch famine birth cohort study: design, validation of exposure, and selected characteristics of subjects after 43 years follow-up
10.1111/j.1365-3016.1993.tb00415.x · 1993 · External reference
Widespread and tissue specific age-related DNA methylation changes in mice
10.1101/gr.096826.109 · 2010 · External reference
Overweight and CpG methylation of the pomc promoter in offspring of high-fat-diet-fed dams are not “reprogrammed” by regular chow diet in rats
10.1096/fj.14-255620 · 2014 · External reference
Session 2: personalised nutrition. Epigenomics: a basis for understanding individual differences?
10.1017/s0029665108008744 · 2008 · External reference
Diet induced epigenetic changes and their implications for health
10.1111/j.1748-1716.2011.02278.x · 2011 · External reference
Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice
10.1002/mnfr.201100008 · 2011 · External reference
Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus
10.1073/pnas.0914328107 · 2010 · External reference
Genome-scale DNA methylation maps of pluripotent and differentiated cells
10.1038/nature07107 · 2008 · External reference
Ancestry dependent DNA methylation and influence of maternal nutrition
10.1371/journal.pone.0118466 · 2015 · External reference
DNA methylation and flavonoids in genitourinary cancers
10.1007/s40495-014-0004-8 · 2015 · External reference
Epigenetic regulation of the igf2/H19 gene cluster
10.1111/cpr.12106 · 2014 · External reference
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome
10.1093/hmg/ddq336 · 2010 · External reference
Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance
10.1128/mcb.24.8.3497-3504.2004 · 2004 · External reference
Curcumin causes promoter hypomethylation and increased expression of FANCF gene in SiHa cell line
10.1007/s11010-012-1240-z · 2012 · External reference
Transgenerational inheritance of glucose intolerance in a mouse model of neonatal overnutrition
10.1210/en.2010-0684 · 2010 · External reference
A long-term high-carbohydrate diet causes an altered ontogeny of pancreatic islets of langerhans in the neonatal rat
10.1203/00006450-200101000-00019 · 2001 · External reference
Changes in mu-opioid receptor expression and function in the mesolimbic system after long-term access to a palatable diet
10.1016/j.pharmthera.2015.07.005 · 2015 · External reference
Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome
10.1113/jphysiol.2009.176156 · 2009 · External reference
Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding
10.1515/jpm.2010.051 · 2010 · External reference
Epigenetic alterations in the brains of fisher 344 rats induced by long-term administration of folate/methyl-deficient diet
10.1016/j.brainres.2008.07.077 · 2008 · External reference
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency
10.1016/j.mrfmmm.2005.06.028 · 2006 · External reference
Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet
10.1016/j.jhep.2009.03.021 · 2009 · External reference
The von Hippel-Lindau tumor suppressor protein sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-κB-dependent antiapoptotic pathway
2003 · External reference
Maternal protein deficiency causes hypermethylation of DNA in the livers of rat fetuses
10.1093/jn/130.7.1821 · 2000 · External reference
Epigenetic reprogramming in mammalian development
10.1126/science.1063443 · 2001 · External reference
Stability and flexibility of epigenetic gene regulation in mammalian development
10.1038/nature05918 · 2007 · External reference
Allelic methylation of H19 and IGF2 in the beckwith – Wiedemann syndrome
10.1093/hmg/3.8.1297 · 1994 · External reference
Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets
10.1073/pnas.1019007108 · 2011 · External reference
Parental allele specific methylation of the human insulin-like growth factor || gene and Beckwith-Wiedemann syndrome
10.1136/jmg.30.5.353 · 1993 · External reference
Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns
10.1093/nar/gkq126 · 2010 · External reference
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming
10.1016/j.cell.2013.04.001 · 2013 · External reference
Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula
2000 · External reference
Molecular adaptations in islets from neonatal rats reared artificially on a high carbohydrate milk formula
10.1016/s0955-2863(01)00176-0 · 2001 · External reference
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
10.1126/science.1170116 · 2009 · External reference
Tissue-specific dysregulation of DNA methylation in aging
10.1111/j.1474-9726.2010.00577.x · 2010 · External reference
Assisted reproductive technologies do not enhance the variability of DNA methylation imprints in human
10.1136/jmg.2009.073189 · 2010 · External reference
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
10.1093/hmg/ddp353 · 2009 · External reference
Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. Delayed postnatal catch-up growth
10.1152/ajpgi.00052.2010 · 2010 · External reference
Organ and gestational age effects of maternal nutrient restriction on global methylation in fetal baboons
10.1111/j.1600-0684.2008.00320.x · 2009 · External reference
The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction
10.1152/ajpregu.00413.2009 · 2010 · External reference
Sex-dependent programming of glucose and fatty acid metabolism in mouse offspring by maternal protein restriction
10.1016/j.genm.2012.01.004 · 2012 · External reference
Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage
10.1096/fj.10-172155 · 2011 · External reference
Chronic high-fat diet drives postnatal epigenetic regulation of µ-opioid receptor in the brain
10.1038/npp.2011.4 · 2011 · External reference
Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes
10.1210/en.2010-0505 · 2010 · External reference
Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation
10.1186/s12864-015-1271-4 · 2015 · External reference
Neonatal overfeeding in female mice predisposes the development of obesity in their male offspring via altered central leptin signalling
10.1111/jne.12281 · 2015 · External reference
Effects of post-weaning diet on metabolic parameters and DNA methylation status of the cryptic promoter in the A(vy) allele of viable yellow mice
10.1016/j.jnutbio.2015.01.003 · 2015 · External reference
Assessing the effects of high methionine intake on DNA methylation
10.1093/jn/136.6.1706s · 2006 · External reference
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
10.1128/mcb.23.15.5293-5300.2003 · 2003 · External reference
Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles
10.1371/journal.pgen.1001252 · 2010 · External reference
Methyl donor supplementation prevents transgenerational amplification of obesity
10.1038/ijo.2008.100 · 2008 · External reference
Maternal epigenetics and methyl supplements affect agouti gene expression in A(vy)/a mice
10.1096/fasebj.12.11.949 · 1998 · External reference
Genistein inhibits DNA methylation and increases expression of tumor suppressor genes in human breast cancer cells
10.1002/gcc.22154 · 2014 · External reference
Global DNA methylation was changed by a maternal high-lipid, high-energy diet during gestation and lactation in male adult mice liver
10.1017/s0007114515000252 · 2015 · External reference
Reconfiguration of DNA methylation in aging
10.1016/j.mad.2015.02.002 · 2015 · External reference
Maternal and post-weaning high-fat, high-sucrose diet modulates glucose homeostasis and hypothalamic pomc promoter methylation in mouse offspring
10.1007/s11011-015-9678-9 · 2015 · External reference