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References from Homeostatic responses to amino acid insufficiency. Local targets link to admitted publications; unresolved targets remain external evidence.
Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats
10.1152/ajpendo.2001.281.3.e430 · 2001 · External reference
Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2
10.1074/jbc.m404559200 · 2004 · External reference
Remodeling of lipid metabolism by dietary restriction of essential amino acids
10.2337/db12-1613 · 2013 · External reference
Asparagine synthetase: regulation by cell stress and involvement in tumor biology
10.1152/ajpendo.00015.2013 · 2013 · External reference
The eIF2 kinase GCN2 is essential for the murine immune system to adapt to amino acid deprivation by asparaginase
2010 · External reference
Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation
10.1152/ajpendo.00256.2014 · 2014 · External reference
Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice
2013 · External reference
The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid
10.1016/j.cmet.2007.01.001 · 2007 · External reference
Amino acid dependent mTORC1 regulation by the lysosomal membrane protein SLC38A9
10.1128/mcb.00125-15 · 2015 · External reference
The transcription factor network associated with the amino acid response in mammalian cells
10.3945/an.112.001891 · 2012 · External reference
ATF4-dependent transcription mediates signaling of amino acid limitation
10.1016/j.tem.2009.05.008 · 2009 · External reference
mTOR signaling in growth control and disease
10.1016/j.cell.2012.03.017 · 2012 · External reference
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21
10.1111/acel.12238 · 2014 · External reference
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
10.1038/nature14107 · 2015 · External reference
Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase
10.1016/s0021-9258(19)84035-8 · 2006 · External reference
General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice
10.1074/jbc.m113.498469 · 2013 · External reference
Role of amino acid transporters in amino acid sensing
10.3945/ajcn.113.070086 · 2014 · External reference
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1
10.1126/science.1257132 · 2015 · External reference
The eukaryotic initiation factor 2 kinase GCN2 protects against hepatotoxicity during asparaginase treatment
10.1152/ajpendo.00080.2013 · 2013 · External reference
GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment
2014 · External reference